Yves Clément
@yvesclement.bsky.social
Assistant Prof @ U-Paris-Cité | Institut Jacques Monod
Molecular evolution and bioinformatics (and some other things, too)
Molecular evolution and bioinformatics (and some other things, too)
Bonjour bonjour
January 26, 2026 at 9:20 AM
Bonjour bonjour
Reposted by Yves Clément
and many more related tools here on my shiny app list for evolutionary processes
bolnicklabresources.wordpress.com/2023/08/04/s...
bolnicklabresources.wordpress.com/2023/08/04/s...
Shiny apps for teaching evolution
The following shiny apps are made by Dan Bolnick for his Evolutionary Medicine class. Each link below is to a simulation of an evolutionary process, in which users can manipulate one or more key pa…
bolnicklabresources.wordpress.com
June 26, 2025 at 2:06 PM
and many more related tools here on my shiny app list for evolutionary processes
bolnicklabresources.wordpress.com/2023/08/04/s...
bolnicklabresources.wordpress.com/2023/08/04/s...
Reposted by Yves Clément
Eukan: a fully automated nuclear genome annotation pipeline for less studied and divergent eukaryotes academic.oup.com/nargab/artic... #protists
January 23, 2026 at 8:00 AM
Eukan: a fully automated nuclear genome annotation pipeline for less studied and divergent eukaryotes academic.oup.com/nargab/artic... #protists
Reposted by Yves Clément
Comme promis, un texte où je persiste et signe : le film "Le mage du Kremlin" est dangereux, car il se met au service du pouvoir russe en diffusant une vision du pays exactement conforme à ce que le Kremlin veut nous faire penser.
colinlebedev.fr/2026/01/22/h...
colinlebedev.fr/2026/01/22/h...
(Hom)mage du Kremlin.
« ‘Le Mage du Kremlin’ (le film) est à peu près le meilleur cadeau que nous puissions faire au Kremlin (le vrai). » J’ai posté ce commentaire hier sur les réseaux sociaux, en sortant de l…
colinlebedev.fr
January 22, 2026 at 12:38 PM
Comme promis, un texte où je persiste et signe : le film "Le mage du Kremlin" est dangereux, car il se met au service du pouvoir russe en diffusant une vision du pays exactement conforme à ce que le Kremlin veut nous faire penser.
colinlebedev.fr/2026/01/22/h...
colinlebedev.fr/2026/01/22/h...
Head of the radiology department
Spin doctors
Médicalise un groupe :
LOFOFORLAX
LOFOFORLAX
January 22, 2026 at 12:06 PM
Head of the radiology department
Reposted by Yves Clément
Very interesting alternative to maximum likelihood to reconstruct ancestral sequences.
Ancestral sequence reconstruction using generative models https://www.biorxiv.org/content/10.64898/2026.01.18.700141v1
January 22, 2026 at 1:59 AM
Very interesting alternative to maximum likelihood to reconstruct ancestral sequences.
Reposted by Yves Clément
Who among us hasn’t produced five pages of crappy writing and then considered defacing the keyboard? Very relatable.
Writing something about ML and the Infinite Monkey Theorem and found this which made me laugh.
January 21, 2026 at 9:57 PM
Who among us hasn’t produced five pages of crappy writing and then considered defacing the keyboard? Very relatable.
Reposted by Yves Clément
🔔 New paper alert 🔔 www.nature.com/articles/s41...
Some regions in the genome replicate early and some late, but the why and how remain poorly understood. DNA replication and 3D genome organization appear linked, raising the question if one may regulate the other? (1/n)
Some regions in the genome replicate early and some late, but the why and how remain poorly understood. DNA replication and 3D genome organization appear linked, raising the question if one may regulate the other? (1/n)
DNA methylation and lncRNA control asynchronous DNA replication at specific imprinted gene domains - Nature Communications
It is not fully understood why genomic loci show asynchronous DNA replication. Here, the authors show that two imprinted gene domains replicate asynchronously between the parental chromosomes due to d...
www.nature.com
January 21, 2026 at 8:53 PM
🔔 New paper alert 🔔 www.nature.com/articles/s41...
Some regions in the genome replicate early and some late, but the why and how remain poorly understood. DNA replication and 3D genome organization appear linked, raising the question if one may regulate the other? (1/n)
Some regions in the genome replicate early and some late, but the why and how remain poorly understood. DNA replication and 3D genome organization appear linked, raising the question if one may regulate the other? (1/n)
Reposted by Yves Clément
January 21, 2026 at 3:45 PM
Reposted by Yves Clément
Two postdoc positions opened in my team @pasteur.fr in Paris on the development of machine learning methods for single-cell multi-omics spatiotemporal data.
See the announcement for all details emploi.cnrs.fr/Offres/CDD/U...
See the announcement for all details emploi.cnrs.fr/Offres/CDD/U...
Portail Emploi CNRS - Offre d'emploi - Two Postdoctoral (M/F) Positions in the Development of Machine Learning Methods for Single-Cell Multi-Omics Spatiotemporal Data
Assurez-vous que votre profil candidat soit correctement renseigné avant de postuler
emploi.cnrs.fr
January 21, 2026 at 3:51 PM
Two postdoc positions opened in my team @pasteur.fr in Paris on the development of machine learning methods for single-cell multi-omics spatiotemporal data.
See the announcement for all details emploi.cnrs.fr/Offres/CDD/U...
See the announcement for all details emploi.cnrs.fr/Offres/CDD/U...
Reposted by Yves Clément
Expressions of interest: Director at MPI EvolBio (f/m/d) — We invite expressions of interest from distinguished scientists in evolutionary biology with a bold, long-term research vision that complements our Institute. More information: www.evolbio.mpg.de/3856225/Dire...
Directors
www.evolbio.mpg.de
January 21, 2026 at 11:15 AM
Expressions of interest: Director at MPI EvolBio (f/m/d) — We invite expressions of interest from distinguished scientists in evolutionary biology with a bold, long-term research vision that complements our Institute. More information: www.evolbio.mpg.de/3856225/Dire...
Did you know that they have a special brand of analysis of variance in Canada.
They call it the ANOVA-Scotia
They call it the ANOVA-Scotia
a cartoon monkey wearing a pirate hat is playing drums in a band
ALT: a cartoon monkey wearing a pirate hat is playing drums in a band
media.tenor.com
January 21, 2026 at 10:50 AM
Did you know that they have a special brand of analysis of variance in Canada.
They call it the ANOVA-Scotia
They call it the ANOVA-Scotia
On a déjà la tenue qu’il va porter
January 21, 2026 at 10:09 AM
On a déjà la tenue qu’il va porter
Reposted by Yves Clément
Ce soir c'est aurores boréales. Mais chez moi c'est plein brouillard.
📷 webcam Chamonix Plan Praz
📷 webcam Chamonix Plan Praz
January 19, 2026 at 9:55 PM
Ce soir c'est aurores boréales. Mais chez moi c'est plein brouillard.
📷 webcam Chamonix Plan Praz
📷 webcam Chamonix Plan Praz
Reposted by Yves Clément
Je viens de voir des aurores boréales de mon balcon. J’ai vu plus d’aurores en 7 ans en Allemagne qu’en 10 ans en Finlande. 😅
January 19, 2026 at 10:07 PM
Je viens de voir des aurores boréales de mon balcon. J’ai vu plus d’aurores en 7 ans en Allemagne qu’en 10 ans en Finlande. 😅
Grand écart cérébral : recevoir en même temps un message de la nounou et un message d'une collègue pour l'évaluation des étudiants
January 19, 2026 at 10:04 AM
Grand écart cérébral : recevoir en même temps un message de la nounou et un message d'une collègue pour l'évaluation des étudiants
Reposted by Yves Clément
A joke for the history buffs:
Germany’s satirical newspaper @der-postillon.com titles: “Vienna Academy of the Arts offers Trump admission as a student — They don’t want to get blamed again“
Germany’s satirical newspaper @der-postillon.com titles: “Vienna Academy of the Arts offers Trump admission as a student — They don’t want to get blamed again“
January 18, 2026 at 1:56 PM
A joke for the history buffs:
Germany’s satirical newspaper @der-postillon.com titles: “Vienna Academy of the Arts offers Trump admission as a student — They don’t want to get blamed again“
Germany’s satirical newspaper @der-postillon.com titles: “Vienna Academy of the Arts offers Trump admission as a student — They don’t want to get blamed again“
Reposted by Yves Clément
There is a special Current Opinion in Genetics & Development issue about genome architecture and expression and it looks great including reviews by @lennarthilbert.bsky.social @yghavi.bsky.social and @wbickmor.bsky.social
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
Current Opinion in Genetics & Development | Genome Architecture and Expression (2026) | ScienceDirect.com by Elsevier
This collection summarizes key aspects of our current experimental and theoretical understanding of eukaryotic genome folding and its relationship with the molecular processes governing cell fate. Ove...
www.sciencedirect.com
January 16, 2026 at 8:39 AM
There is a special Current Opinion in Genetics & Development issue about genome architecture and expression and it looks great including reviews by @lennarthilbert.bsky.social @yghavi.bsky.social and @wbickmor.bsky.social
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
Reposted by Yves Clément
PCA is one of those techniques that sounds unreasonable (yeah sure we all want to fit a p-dimensional ellipsoid to our data) but turns out to be a reasonable solution to a wide range of problems.
Also: I do hope stackexchange has been archived, because it is my gen's library of alexandria
Also: I do hope stackexchange has been archived, because it is my gen's library of alexandria
still one of the best explanations of principal component analysis (pca), explained at different levels from layman to the more math inclined stats.stackexchange.com/a/140579/132...
Making sense of principal component analysis, eigenvectors & eigenvalues
In today's pattern recognition class my professor talked about PCA, eigenvectors and eigenvalues.
I understood the mathematics of it. If I'm asked to find eigenvalues etc. I'll do it correctly li...
stats.stackexchange.com
January 13, 2026 at 4:13 PM
PCA is one of those techniques that sounds unreasonable (yeah sure we all want to fit a p-dimensional ellipsoid to our data) but turns out to be a reasonable solution to a wide range of problems.
Also: I do hope stackexchange has been archived, because it is my gen's library of alexandria
Also: I do hope stackexchange has been archived, because it is my gen's library of alexandria
Reposted by Yves Clément
Just sharing new tool written by Vincent Ranwez to view and manipulate sequences and alignments directly in your terminal
github.com/ranwez-searc...
Pretty convenient!
github.com/ranwez-searc...
Pretty convenient!
GitHub - ranwez-search/SeqTUI: A fast terminal-based viewer and command-line toolkit for molecular sequences (DNA, AA). View, translate, convert (to FASTA), and combine sequences aligned or not — all ...
A fast terminal-based viewer and command-line toolkit for molecular sequences (DNA, AA). View, translate, convert (to FASTA), and combine sequences aligned or not — all from the terminal. - ranwez-...
github.com
January 13, 2026 at 12:42 PM
Just sharing new tool written by Vincent Ranwez to view and manipulate sequences and alignments directly in your terminal
github.com/ranwez-searc...
Pretty convenient!
github.com/ranwez-searc...
Pretty convenient!
Reposted by Yves Clément
Sortie ce jour du rapport en Anses sur les réseaux sociaux et les adolescents auquel j’ai participé.
Des risques identifiés, comme dans tous les rapports en Anses 😉, une demande forte de régulation des réseaux sociaux sécurisés pour tous et de l’éducation aux médias
www.anses.fr/fr/content/s...
Des risques identifiés, comme dans tous les rapports en Anses 😉, une demande forte de régulation des réseaux sociaux sécurisés pour tous et de l’éducation aux médias
www.anses.fr/fr/content/s...
Sécuriser les usages des réseaux sociaux pour protéger la santé des adolescents | Anses - Agence nationale de sécurité sanitaire de l’alimentation, de l’environnement et du travail
Le développement extrêmement rapide des usages des réseaux sociaux numériques par les adolescents suscite des préoccupations croissantes. L’Anses a mené une expertise scientifique collective approfond...
www.anses.fr
January 13, 2026 at 8:00 AM
Sortie ce jour du rapport en Anses sur les réseaux sociaux et les adolescents auquel j’ai participé.
Des risques identifiés, comme dans tous les rapports en Anses 😉, une demande forte de régulation des réseaux sociaux sécurisés pour tous et de l’éducation aux médias
www.anses.fr/fr/content/s...
Des risques identifiés, comme dans tous les rapports en Anses 😉, une demande forte de régulation des réseaux sociaux sécurisés pour tous et de l’éducation aux médias
www.anses.fr/fr/content/s...
Reposted by Yves Clément
🧬 We’re #Hiring a #Bioinformatician/ Computational Biologist!
#Single-cell genomics, #Epigenomics & #3Dgenome biology in #Zebrafish #DevBio 🐟
📍 @cabd-upo-csic.bsky.social, CABD, Seville (Spain)
🕒 Full-time, 3-year position (start March 2026)
📅 Apply by Feb 15, 2026
👉 drive.google.com/file/d/1M8rp...
#Single-cell genomics, #Epigenomics & #3Dgenome biology in #Zebrafish #DevBio 🐟
📍 @cabd-upo-csic.bsky.social, CABD, Seville (Spain)
🕒 Full-time, 3-year position (start March 2026)
📅 Apply by Feb 15, 2026
👉 drive.google.com/file/d/1M8rp...
Job offer 2026.pdf
drive.google.com
January 12, 2026 at 3:57 PM
🧬 We’re #Hiring a #Bioinformatician/ Computational Biologist!
#Single-cell genomics, #Epigenomics & #3Dgenome biology in #Zebrafish #DevBio 🐟
📍 @cabd-upo-csic.bsky.social, CABD, Seville (Spain)
🕒 Full-time, 3-year position (start March 2026)
📅 Apply by Feb 15, 2026
👉 drive.google.com/file/d/1M8rp...
#Single-cell genomics, #Epigenomics & #3Dgenome biology in #Zebrafish #DevBio 🐟
📍 @cabd-upo-csic.bsky.social, CABD, Seville (Spain)
🕒 Full-time, 3-year position (start March 2026)
📅 Apply by Feb 15, 2026
👉 drive.google.com/file/d/1M8rp...
Reposted by Yves Clément
La crise des œufs dure.
Pourquoi les œufs ont presque disparu des rayons de vos supermarchés
Pourquoi les oeufs ont presque disparu des rayons de vos supermarchés
Rayons vides, ruptures de stock à répétition, et consommateurs désemparés : depuis plusieurs semaines, les œufs se font rares dans de nombreux supermarchés en France. En cause, une combinaison de facteurs allant des épidémies animales aux conditions météo, en passant par une consommation en forte hausse.
www.rtl.fr
January 12, 2026 at 7:10 PM
La crise des œufs dure.
"Coucou, votre AG de copro est dans une semaine tout pile, et vous avez jusqu'à demain pour nous dire si vous avez un truc à rajouter à l'ordre du jour"
a woman is making a funny face while wearing a tank top .
ALT: a woman is making a funny face while wearing a tank top .
media.tenor.com
January 12, 2026 at 4:56 PM
"Coucou, votre AG de copro est dans une semaine tout pile, et vous avez jusqu'à demain pour nous dire si vous avez un truc à rajouter à l'ordre du jour"