WeigandLab
@weigandlab.bsky.social
RNA biochemist; like RNA structures and RBPs; Marburg University, Germany
Pinned
WeigandLab
@weigandlab.bsky.social
· Sep 4
Join us for an online seminar on ASO therapy, September 24th 12.30 pm
#RNAtherapeutics #Antisense
@gbmev.bsky.social @oligogirl.bsky.social
#RNAtherapeutics #Antisense
@gbmev.bsky.social @oligogirl.bsky.social
Reposted by WeigandLab
Researchers of @hellmichgroup.bsky.social at #UniJena Cluster of Excellence @microverse.bsky.social have deciphered a key mechanism of antibiotic resistance. They showed how the bacterium applies the energy required to transport the drug out of its cell.
➡️ www.uni-jena.de/en/381040/sp...
➡️ www.uni-jena.de/en/381040/sp...
Specific activation instead of continuous operation: How bacteria save energy and what this means for antibiotic resistances
Researchers in the Cluster of Excellence “Balance of the Microverse” at the University of Jena decipher a key mechanism of antibiotic resistance pumps
www.uni-jena.de
January 9, 2026 at 11:24 AM
Researchers of @hellmichgroup.bsky.social at #UniJena Cluster of Excellence @microverse.bsky.social have deciphered a key mechanism of antibiotic resistance. They showed how the bacterium applies the energy required to transport the drug out of its cell.
➡️ www.uni-jena.de/en/381040/sp...
➡️ www.uni-jena.de/en/381040/sp...
Reposted by WeigandLab
🚨We are looking for a coordinator located at @uni-wuerzburg.de for our new excellence cluster NUCLEATE - Cluster of Nucleic Acid Sciences and Technologies 👇
www.uni-wuerzburg.de/fileadmin/03...
Deadline: Jan 31 st, 2026
www.uni-wuerzburg.de/fileadmin/03...
Deadline: Jan 31 st, 2026
www.uni-wuerzburg.de
January 8, 2026 at 1:08 PM
🚨We are looking for a coordinator located at @uni-wuerzburg.de for our new excellence cluster NUCLEATE - Cluster of Nucleic Acid Sciences and Technologies 👇
www.uni-wuerzburg.de/fileadmin/03...
Deadline: Jan 31 st, 2026
www.uni-wuerzburg.de/fileadmin/03...
Deadline: Jan 31 st, 2026
Reposted by WeigandLab
If you are a #PhD candidate and want to attend #Biochemistry2026 (veranstaltungen.gdch...), make sure to apply for our meeting award, which comes with 500 € for the attendance and a free year of membership in @gdchbiochem.bsky.social
en.gdch.de/network-s...
en.gdch.de/network-s...
January 7, 2026 at 12:00 PM
If you are a #PhD candidate and want to attend #Biochemistry2026 (veranstaltungen.gdch...), make sure to apply for our meeting award, which comes with 500 € for the attendance and a free year of membership in @gdchbiochem.bsky.social
en.gdch.de/network-s...
en.gdch.de/network-s...
Reposted by WeigandLab
A new year brings new opportunities: we are looking to fill a permanent professorship position with a Microbiologist preferably with expertise on archaeal biology, RNA biology or imaging techniques to unravel cell biology in prokaryotes! Please share and/or apply :)! www.nature.com/naturecareer...
Professurship (W2) in Microbiology - Regensburg (Stadt), Bayern (DE) job with Universität Regensburg | 12851113
UNIVERSITY OF REGENSBURG The Faculty of Biology and Pre-Clinical Medicine invites applications for a Professurship (W2) in Microbiology To be...
www.nature.com
January 5, 2026 at 9:46 AM
A new year brings new opportunities: we are looking to fill a permanent professorship position with a Microbiologist preferably with expertise on archaeal biology, RNA biology or imaging techniques to unravel cell biology in prokaryotes! Please share and/or apply :)! www.nature.com/naturecareer...
Reposted by WeigandLab
That’s great news. mRNA vaccines are game changers-hopefully 2026 brings us more of these discoveries.
Mit mRNA-Impfstoff gegen die Lungenpest www.juedische-allgemeine.de?p=2578106
Der weltweit erste mRNA-basierte Impfstoff gegen ein tödliches antibiotika-resistentes Bakterium
#GoodNews
Der weltweit erste mRNA-basierte Impfstoff gegen ein tödliches antibiotika-resistentes Bakterium
#GoodNews
Mit mRNA-Impfstoff gegen die Lungenpest?
In Israel ist der weltweit erste mRNA-basierte Impfstoff gegen ein tödliches antibiotika-resistentes Bakterium entwickelt worden
www.juedische-allgemeine.de
January 4, 2026 at 1:36 PM
That’s great news. mRNA vaccines are game changers-hopefully 2026 brings us more of these discoveries.
Reposted by WeigandLab
Thanks to all who provide these illustrations for free - it helps so much for teaching etc! It’s like a Christmas present again and again ☺️
A free, open-access library of high-quality organism illustrations for science communication
A free, open-access library of high-quality organism illustrations for science communication
We create vector graphics of model organisms and emerging biological research organisms to enhance our publications. We’re sharing these editable graphics under a CC0 license for other scientists to...
doi.org
December 30, 2025 at 7:20 AM
Thanks to all who provide these illustrations for free - it helps so much for teaching etc! It’s like a Christmas present again and again ☺️
Reposted by WeigandLab
This is the "SEA SHEEP" (Costasiella kuroshimae) & it took the old axiom: "you are what you eat" VERY literally.
It eats algae & rather than just digest them, it harvests the chloroplasts & becomes PHOTOSYNTHETIC. Solar slug!
Also, some of its cousins can rip their own heads off.
It eats algae & rather than just digest them, it harvests the chloroplasts & becomes PHOTOSYNTHETIC. Solar slug!
Also, some of its cousins can rip their own heads off.
a close up of a green and white sponge with purple spots
Alt: A green and white sea sheep grazes on a green lawn of algae on a surface underwater.
media.tenor.com
December 27, 2025 at 5:02 PM
This is the "SEA SHEEP" (Costasiella kuroshimae) & it took the old axiom: "you are what you eat" VERY literally.
It eats algae & rather than just digest them, it harvests the chloroplasts & becomes PHOTOSYNTHETIC. Solar slug!
Also, some of its cousins can rip their own heads off.
It eats algae & rather than just digest them, it harvests the chloroplasts & becomes PHOTOSYNTHETIC. Solar slug!
Also, some of its cousins can rip their own heads off.
Reposted by WeigandLab
RIL-seq boosts the study of sRNAs. Here comes its first application to intracellular bacteria. Plus, 10 years after its characterization, we now present an RNA sponge of Salmonella PinT.
Congrats to @kooshapour.bsky.social & great collaboration w/ @jorg-vogel-lab.bsky.social!
doi.org/10.1093/nar/...
Congrats to @kooshapour.bsky.social & great collaboration w/ @jorg-vogel-lab.bsky.social!
doi.org/10.1093/nar/...
Intramacrophage RIL-seq uncovers an RNA antagonist of the Salmonella virulence-associated small RNA PinT
Abstract. Salmonella virulence chiefly relies upon two major pathogenicity islands, SPI-1 and SPI-2, which enable host cell invasion and intracellular surv
doi.org
December 27, 2025 at 2:06 PM
RIL-seq boosts the study of sRNAs. Here comes its first application to intracellular bacteria. Plus, 10 years after its characterization, we now present an RNA sponge of Salmonella PinT.
Congrats to @kooshapour.bsky.social & great collaboration w/ @jorg-vogel-lab.bsky.social!
doi.org/10.1093/nar/...
Congrats to @kooshapour.bsky.social & great collaboration w/ @jorg-vogel-lab.bsky.social!
doi.org/10.1093/nar/...
Reposted by WeigandLab
Online Now: Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii Online now:
Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii
Using the latest advances in instrumentation and computational workflows, Kelley et al. present a large-scale annotated cryo-electron tomography dataset of the model green alga, Chlamydomonas reinhardtii. This unprecedented community resource is rich in high-resolution biological information and empowers the development of new methods for visual proteomics.
dlvr.it
December 24, 2025 at 8:14 PM
Online Now: Toward community-driven visual proteomics with large-scale cryo-electron tomography of Chlamydomonas reinhardtii Online now:
Reposted by WeigandLab
Are you interested in cutting-edge #Biochemistry and #ChemBio? Join us for the GDCh #Biochemistry2026 conference in Würzburg on March 16th to 18th, 2026.
Registration is now open and you can submit an abstract until January 10th, 2026: veranstaltungen.gdch...
(1/2)
Registration is now open and you can submit an abstract until January 10th, 2026: veranstaltungen.gdch...
(1/2)
December 22, 2025 at 11:00 AM
Are you interested in cutting-edge #Biochemistry and #ChemBio? Join us for the GDCh #Biochemistry2026 conference in Würzburg on March 16th to 18th, 2026.
Registration is now open and you can submit an abstract until January 10th, 2026: veranstaltungen.gdch...
(1/2)
Registration is now open and you can submit an abstract until January 10th, 2026: veranstaltungen.gdch...
(1/2)
Reposted by WeigandLab
December 23, 2025 at 8:34 AM
Reposted by WeigandLab
We’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development.
www.nature.com/articles/s41...
A thread.
www.nature.com/articles/s41...
A thread.
Mycobacterium tuberculosis overcomes phosphate starvation by extensively remodelling its lipidome with phosphorus-free lipids - Nature Communications
Here, the authors show that Mycobacterium tuberculosis manipulates lipid metabolism to overcome host restriction, by remodelling its lipidome and utilising host lipids as an alternative phosphate sour...
www.nature.com
December 22, 2025 at 1:11 PM
We’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development.
www.nature.com/articles/s41...
A thread.
www.nature.com/articles/s41...
A thread.
Reposted by WeigandLab
Proud to bring together so many excellent invited speakers for our RTG 2355 International Conference next September, and looking forward to welcoming you @jlugiessen.bsky.social!
👉 tinyurl.com/rtg2355conf
👉 tinyurl.com/rtg2355conf
Happy to announce our RTG 2355 International Conference “Regulatory landscapes of RNA: From code to control”, Sept 14-16, 2026 in Giessen, Germany. Topics cover #RNA as messenger, recruiting platform, sponge, regulator & sensor. 👉tinyurl.com/rtg2355conf
Save the date – registration opens May 1!
Save the date – registration opens May 1!
December 19, 2025 at 10:20 AM
Proud to bring together so many excellent invited speakers for our RTG 2355 International Conference next September, and looking forward to welcoming you @jlugiessen.bsky.social!
👉 tinyurl.com/rtg2355conf
👉 tinyurl.com/rtg2355conf
Reposted by WeigandLab
Take advantage of this fantastic opportunity to become part of the SCALE community! Several professorships and group leader positions are available at Goethe University and FIAS. We are looking for professors in the fields of molecular microbiology, cellular biochemistry, and molecular biochemistry.
⏰Call for Applications - Join Our Team and Help Shape Our Cluster
@goetheuni.bsky.social and the Cluster of Excellence SCALE - Subcellular Architecture of Life are seeking 3 highly motivated scientists to join a vibrant and innovative research community on Campus Riedberg.
Share with your network!
@goetheuni.bsky.social and the Cluster of Excellence SCALE - Subcellular Architecture of Life are seeking 3 highly motivated scientists to join a vibrant and innovative research community on Campus Riedberg.
Share with your network!
December 19, 2025 at 10:44 PM
Take advantage of this fantastic opportunity to become part of the SCALE community! Several professorships and group leader positions are available at Goethe University and FIAS. We are looking for professors in the fields of molecular microbiology, cellular biochemistry, and molecular biochemistry.
Reposted by WeigandLab
Looking for a POSTDOC to work on jumbo phages (those with large genomes and fascinating cell biology), using our latest ASO technology (Gerovac M et al. 2025 Nature) to define RNA export mechanisms as well as to help to advance phage therapy. Here's the job ad.
December 19, 2025 at 10:51 PM
Looking for a POSTDOC to work on jumbo phages (those with large genomes and fascinating cell biology), using our latest ASO technology (Gerovac M et al. 2025 Nature) to define RNA export mechanisms as well as to help to advance phage therapy. Here's the job ad.
Reposted by WeigandLab
Website and registration for the INSERM workshop on "Modern Methods in Molecular Parasitology" are now live! Open to all interested! Fantastic programme! ateliersinserm.dakini-pco.com/en
December 18, 2025 at 1:48 PM
Website and registration for the INSERM workshop on "Modern Methods in Molecular Parasitology" are now live! Open to all interested! Fantastic programme! ateliersinserm.dakini-pco.com/en
Reposted by WeigandLab
GBM Lunch on December 17, 12:30 PM (CET)
We’re excited to welcome Mikel Garcia-Marcos (Boston University) presenting: “The Secret Life of G Proteins”
Session chair: Tassula Proikas-Cezanne (@unituebingen.bsky.social)
Organized by the GBM Study Group Autophagy.
#GBMLunch #Autophagy #GProteins
We’re excited to welcome Mikel Garcia-Marcos (Boston University) presenting: “The Secret Life of G Proteins”
Session chair: Tassula Proikas-Cezanne (@unituebingen.bsky.social)
Organized by the GBM Study Group Autophagy.
#GBMLunch #Autophagy #GProteins
December 11, 2025 at 11:20 AM
GBM Lunch on December 17, 12:30 PM (CET)
We’re excited to welcome Mikel Garcia-Marcos (Boston University) presenting: “The Secret Life of G Proteins”
Session chair: Tassula Proikas-Cezanne (@unituebingen.bsky.social)
Organized by the GBM Study Group Autophagy.
#GBMLunch #Autophagy #GProteins
We’re excited to welcome Mikel Garcia-Marcos (Boston University) presenting: “The Secret Life of G Proteins”
Session chair: Tassula Proikas-Cezanne (@unituebingen.bsky.social)
Organized by the GBM Study Group Autophagy.
#GBMLunch #Autophagy #GProteins
Reposted by WeigandLab
The story of how multiple RBPs cooperate to repress translation is now out in @cp-cellreports.bsky.social by @marcopayr.bsky.social and in a great collaboration with @hennig-lab.bsky.social!
www.cell.com/cell-reports...
www.cell.com/cell-reports...
November 7, 2025 at 3:34 PM
The story of how multiple RBPs cooperate to repress translation is now out in @cp-cellreports.bsky.social by @marcopayr.bsky.social and in a great collaboration with @hennig-lab.bsky.social!
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by WeigandLab
It’s out 🥳🥳. Amazing new insights into Paraspeckles by SMART 3D STED imaging. Paraspeckles can be polar and fuse and have an interesting loop that contacts the nucleoplasm. Kudos to @heilemannlab.bsky.social, Sjoerd Stallinga and Bernd Rieger.
We developed a 'smart STED microscope' to detect rare objects/events in cells, and unraveled the 3D morphology of a nuclear membraneless organelle (paraspeckle). Amazing collaboration with Sjoerd Stallinga, Bernd Rieger (TU Delft) and @mixmue.bsky.social 🙏 (1/3) www.nature.com/articles/s41...
November 28, 2025 at 7:56 PM
It’s out 🥳🥳. Amazing new insights into Paraspeckles by SMART 3D STED imaging. Paraspeckles can be polar and fuse and have an interesting loop that contacts the nucleoplasm. Kudos to @heilemannlab.bsky.social, Sjoerd Stallinga and Bernd Rieger.
Reposted by WeigandLab
Exceptional work by Enya (TU Delft) and Laurell (Frankfurt) 💪 and a great team 👍 & great support by our Exc Cluster @scale-cluster-ffm.bsky.social @goetheuni.bsky.social & we thank our Editor and the Reviewers for their valuable input @natcomms.nature.com
#FluorescenceFriday #smartmicroscopy #RNA
#FluorescenceFriday #smartmicroscopy #RNA
November 28, 2025 at 3:12 PM
Exceptional work by Enya (TU Delft) and Laurell (Frankfurt) 💪 and a great team 👍 & great support by our Exc Cluster @scale-cluster-ffm.bsky.social @goetheuni.bsky.social & we thank our Editor and the Reviewers for their valuable input @natcomms.nature.com
#FluorescenceFriday #smartmicroscopy #RNA
#FluorescenceFriday #smartmicroscopy #RNA
Reposted by WeigandLab
New publication alert 🎉
Our latest paper explores how small molecules can bind SARS-CoV-2 RNA, combining in silico screening with NMR experiments to uncover promising RNA-targeting candidates.
full text: chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
#RNA #NMR #screening #drugtargeting
Our latest paper explores how small molecules can bind SARS-CoV-2 RNA, combining in silico screening with NMR experiments to uncover promising RNA-targeting candidates.
full text: chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
#RNA #NMR #screening #drugtargeting
Integrative In Silico and In Vitro Screening of Low Molecular Weight Compounds Targeting SARS‐CoV‐2 RNA Elements
A combined virtual and nuclear magnetic resonance (NMR)-based screening approach identifies small molecules that bind conserved SARS-CoV-2 RNA structures. Diverse compound libraries are screened usin...
chemistry-europe.onlinelibrary.wiley.com
December 1, 2025 at 7:30 AM
New publication alert 🎉
Our latest paper explores how small molecules can bind SARS-CoV-2 RNA, combining in silico screening with NMR experiments to uncover promising RNA-targeting candidates.
full text: chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
#RNA #NMR #screening #drugtargeting
Our latest paper explores how small molecules can bind SARS-CoV-2 RNA, combining in silico screening with NMR experiments to uncover promising RNA-targeting candidates.
full text: chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
#RNA #NMR #screening #drugtargeting
Reposted by WeigandLab
🚨Attention prospective PhD students🚨
Are you interested in molecular mechanisms, RNA viruses, structural biology or biophysics? 🧬🦠🧪
We have THREE fully-funded PhD projects available for October 2026 entry:
www.findaphd.com/phds/?Keywor...
Please share/repost, and get in touch if you're interested
Are you interested in molecular mechanisms, RNA viruses, structural biology or biophysics? 🧬🦠🧪
We have THREE fully-funded PhD projects available for October 2026 entry:
www.findaphd.com/phds/?Keywor...
Please share/repost, and get in touch if you're interested
chris hill PhD Projects, Programmes & Scholarships - 3 PhDs Listed
FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in chris hill. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.
www.findaphd.com
November 13, 2025 at 7:54 PM
🚨Attention prospective PhD students🚨
Are you interested in molecular mechanisms, RNA viruses, structural biology or biophysics? 🧬🦠🧪
We have THREE fully-funded PhD projects available for October 2026 entry:
www.findaphd.com/phds/?Keywor...
Please share/repost, and get in touch if you're interested
Are you interested in molecular mechanisms, RNA viruses, structural biology or biophysics? 🧬🦠🧪
We have THREE fully-funded PhD projects available for October 2026 entry:
www.findaphd.com/phds/?Keywor...
Please share/repost, and get in touch if you're interested
Reposted by WeigandLab
🎓 PhD completed? Apply for the 𝐆𝐁𝐌 𝐃𝐨𝐜𝐭𝐨𝐫𝐚𝐥 𝐀𝐰𝐚𝐫𝐝𝐬 (€1,500)
🔬 Open to outstanding research in biochemistry & molecular biology.
🗓 𝐃𝐞𝐚𝐝𝐥𝐢𝐧𝐞: 30 Nov 2025
📍 Awards at the Mosbach Colloquium 2026
Self-nominations welcome, GBM membership not required.
👉 gbm-online.de/en/news-even...
#PhDlife #Awards
🔬 Open to outstanding research in biochemistry & molecular biology.
🗓 𝐃𝐞𝐚𝐝𝐥𝐢𝐧𝐞: 30 Nov 2025
📍 Awards at the Mosbach Colloquium 2026
Self-nominations welcome, GBM membership not required.
👉 gbm-online.de/en/news-even...
#PhDlife #Awards
November 13, 2025 at 8:31 AM
Reposted by WeigandLab
📢 Postdoc position: Biochemistry & Bacterial cell biology
in our group at Marburg University, Germany, funded by the ERC Advanced Grant "C-SWITCH"
🔗More information at shorturl.at/OlvlL
📅Deadline: Nov 30, 2025
Please repost. #Postdoc
in our group at Marburg University, Germany, funded by the ERC Advanced Grant "C-SWITCH"
🔗More information at shorturl.at/OlvlL
📅Deadline: Nov 30, 2025
Please repost. #Postdoc
November 10, 2025 at 6:15 PM
📢 Postdoc position: Biochemistry & Bacterial cell biology
in our group at Marburg University, Germany, funded by the ERC Advanced Grant "C-SWITCH"
🔗More information at shorturl.at/OlvlL
📅Deadline: Nov 30, 2025
Please repost. #Postdoc
in our group at Marburg University, Germany, funded by the ERC Advanced Grant "C-SWITCH"
🔗More information at shorturl.at/OlvlL
📅Deadline: Nov 30, 2025
Please repost. #Postdoc
Reposted by WeigandLab
GBM Lunch on Nov. 19, 12.30pm
Speaker: Adrian Bunzel,
@mpimicrobiomarburg.bsky.social
Title: Creating Enzymes by Computational Design and Directed Evolution
Chair: Valentina Piano @valentinapiano.bsky.social (CECAD, Köln)
Organized by GBM Young Investigators.
#GBMLunch #GBM_YI
Speaker: Adrian Bunzel,
@mpimicrobiomarburg.bsky.social
Title: Creating Enzymes by Computational Design and Directed Evolution
Chair: Valentina Piano @valentinapiano.bsky.social (CECAD, Köln)
Organized by GBM Young Investigators.
#GBMLunch #GBM_YI
November 7, 2025 at 1:50 PM
GBM Lunch on Nov. 19, 12.30pm
Speaker: Adrian Bunzel,
@mpimicrobiomarburg.bsky.social
Title: Creating Enzymes by Computational Design and Directed Evolution
Chair: Valentina Piano @valentinapiano.bsky.social (CECAD, Köln)
Organized by GBM Young Investigators.
#GBMLunch #GBM_YI
Speaker: Adrian Bunzel,
@mpimicrobiomarburg.bsky.social
Title: Creating Enzymes by Computational Design and Directed Evolution
Chair: Valentina Piano @valentinapiano.bsky.social (CECAD, Köln)
Organized by GBM Young Investigators.
#GBMLunch #GBM_YI