Sharma Lab
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sharmalab.bsky.social
Sharma Lab
@sharmalab.bsky.social
130 followers 140 following 3 posts
Our lab @uniwuerzburg.bsky.social focuses on gene regulation & virulence control in bacterial pathogens.
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sharmalab.bsky.social
🚨We are looking for a coordinator located at @uni-wuerzburg.de for our new excellence cluster NUCLEATE - Cluster of Nucleic Acid Sciences and Technologies 👇
www.uni-wuerzburg.de/fileadmin/03...
Deadline: Jan 31 st, 2026
www.uni-wuerzburg.de
January 8, 2026 at 1:08 PM
Reposted by Sharma Lab
carmen-aguilar.bsky.social
Our first paper is out today in @natmicrobiol.nature.com!

We introduce a prostate organoid model and show that UPEC invades prostate cells via FimH binding to the prostate-specific protein PAPP. A step toward targeted therapies against bacterial prostatitis. 🎉

#UTI #UPEC #Organoids #AMR
Uropathogenic Escherichia coli invade luminal prostate cells via FimH–PPAP receptor binding - Nature Microbiology
Uropathogenic Escherichia coli infection of a murine prostate organoid model reveals a bacterial FimH–host prostatic acid phosphatase adhesin-receptor interaction enabling invasion and replication wit...
www.nature.com
January 8, 2026 at 11:12 AM
Reposted by Sharma Lab
monaalzheimer.bsky.social
🧪We are hiring #MicroSky🧪
Postdoc position in #microbiology #bioinformatics for our @volkswagenstiftung.de funded MOMENTUM project. Join us to study bacterial gene expression with #microfluidics and #microscopy.
➡️ www.uni-wuerzburg.de/fileadmin/03290000/2025/Postdoc_MOMENTUM_Sharma_2025-08.pdf
July 16, 2025 at 8:14 AM
Reposted by Sharma Lab
uni-wuerzburg.de
Erfolg auf ganzer Linie: zwei Exzellenzcluster für Würzburg! 🥂🚀
Im Rahmen der #ExStra wird nicht nur der Quantenphysik-Cluster ctd.qmat weiterhin gefördert. Mit NUCLEATE, einem Forschungsprojekt zu Nukleinsäuren, kommt noch ein zweiter Cluster hinzu!
➡️ go.uniwue.de/xstra25
Freude über den Doppelerfolg: Zwei Würzburger Forschungsvorhaben haben sich im Exzellenzwettbewerb durchgesetzt und erhalten Mittel aus der begehrten Millionenförderung. Von links: Caroline Kisker (Würzburger Koordinatorin von NUCLEATE und Vizepräsidentin), Cynthia Sharma (Würzburger Speakerin von NUCLEATE), Ralph Claessen (Würzburger Speaker von ctd.qmat) und Universitätspräsident Paul Pauli (Bild: Jonas Blank / JMU)
May 22, 2025 at 4:49 PM
sharmalab.bsky.social
New preprint on our #Campylobacter Tn-seq screen in a 3D tissue model revealing a #smallprotein crucial for motility by @monaalzheimer.bsky.social @kathrinfroschauer.bsky.social @campy-bara.bsky.social together with the Beeby & Hendrixson labs: 👇
www.biorxiv.org/content/10.1...
@uni-wuerzburg.de
Functional genomics of Campylobacter-host interactions in an intestinal tissue model reveals a small lipoprotein essential for flagellar assembly
Campylobacter jejuni is currently the most common cause of bacterial gastroenteritis worldwide. However, its genome provides few clues about how it interacts with the host. Moreover, infection screens...
www.biorxiv.org
April 4, 2025 at 2:50 PM
sharmalab.bsky.social
We are happy to share our new paper on the #Campylobacter translatome out now in @naturecomms.bsky.social. Many congrats to @kathrinfroschauer.bsky.social & @campy-bara.bsky.social and all collaboration partners! #SPP2002 #smallproteins @uni-wuerzburg.de

www.nature.com/articles/s41467-025-58329-w
Complementary Ribo-seq approaches map the translatome and provide a small protein census in the foodborne pathogen Campylobacter jejuni - Nature Communications
Bacterial genomes still contain many hidden and uncharacterized genes. Using complementary Ribo-seq approaches, Froschauer, Svensson et al. here annotate start and stop codons of Campylobacter jejuni,...
www.nature.com
April 1, 2025 at 9:08 AM