The discovery of quorum-sensing responsive linear plasmid phages has transformed understanding of phage-bacterial interactions by demonstrating inter-domain chemical communication. To date, however, e...

A secondary metabolite sensitizes competitor Bacillus subtilis to a wide panel of lytic phages by sequestering iron and preventing the activation of Spo0A.

PhD Project - MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Li...

Mathematical modelling and experimental tests reveal principles that govern displacement of a resident strain by an invader in microbial communities.

Competition significantly influences bacterial population dynamics, particularly in how strains interact within and between hosts. This study shows that within-host competition in Streptococcus pneumo...

Abstract. Plasmids are a ubiquitous feature of bacterial genomes, but the forces driving genes and phenotypes to become associated with plasmids are poorly

The Department of Quantitative Biomedicine is an interdisciplinary biomedical research unit that combines basic science with biotechnological and medical research, using both experimental and computat...

One Health is an integrative concept striving for healthy environments, animals, and humans. Microbes play a fundamental role for this concept as they are key drivers of ecosystem stability and host h...

One Health is an integrative concept striving for healthy environments, animals, and humans. Microbes play a fundamental role for this concept as they are key drivers of ecosystem stability and host health. A central microbial feature across various environments is the secretion of siderophores, low-molecular-weight metabolites that chelate ferric iron (Fe3+) with high affinity. We propose that, by steering iron and metal availability, siderophores can be important for One Health in four key areas via: (i) enhancing crop yield, (ii) mitigating heavy metal pollution, (iii) preventing pathogen colonization, and (iv) serving as potential treatments for established infections. Collectively, siderophores are attractive molecules to complement our efforts in increasing human, animal, and environmental health.

The members of CMFI can breathe a sigh of relief: On January 1, 2026, the Tübingen Cluster of Excellence will enter its second funding period with a duration of seven years. This was announced by the ...