UK Cilia and Centrosome Network
@ukcilianetwork.bsky.social
A supportive network for the cilia research community to share research and expertise. Account managed by Dr. Girish Ram Mali and ECR Advisory Group
https://www.cilianetwork.org.uk/
https://www.cilianetwork.org.uk/
Pinned
📢📢📢 Klaxon call for all cilia enthusiasts 📢 📢📢! Registrations still open + free. There are still spots for a few posters. Come along its London calling. Also this year we will have a special cilia imaging session organised by Kirsty Wan @micromotility.bsky.social
www.ucl.ac.uk/child-health...
www.ucl.ac.uk/child-health...
Reposted by UK Cilia and Centrosome Network
While trying to steer clear of the ‘best organelle’ debate, we’re delighted to highlight #JCSciliaSI, guest edited by @cilialab.bsky.social & @lottepedersen.bsky.social.
And, we hope that even the most ardent fans of other organelles can agree that cilia are certainly beautiful to image!
And, we hope that even the most ardent fans of other organelles can agree that cilia are certainly beautiful to image!
JCS Special Issue - 'Cilia and Flagella: from Basic Biology to Disease' - FocalPlane
JCS Special Issue - 'Cilia and Flagella: from Basic Biology to Disease' - News
focalplane.biologists.com
November 13, 2025 at 11:26 AM
While trying to steer clear of the ‘best organelle’ debate, we’re delighted to highlight #JCSciliaSI, guest edited by @cilialab.bsky.social & @lottepedersen.bsky.social.
And, we hope that even the most ardent fans of other organelles can agree that cilia are certainly beautiful to image!
And, we hope that even the most ardent fans of other organelles can agree that cilia are certainly beautiful to image!
Reposted by UK Cilia and Centrosome Network
Rudolfo Karl, Elvira Mass, Dagmar Wachten @wachtenlab.bsky.social and colleagues discover that renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease.
#JCSciliaSI
journals.biologists.com/jcs/article/...
#JCSciliaSI
journals.biologists.com/jcs/article/...
November 14, 2025 at 2:14 PM
Rudolfo Karl, Elvira Mass, Dagmar Wachten @wachtenlab.bsky.social and colleagues discover that renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease.
#JCSciliaSI
journals.biologists.com/jcs/article/...
#JCSciliaSI
journals.biologists.com/jcs/article/...
Reposted by UK Cilia and Centrosome Network
Thrilled to share "in situ APEX activation" (iAPEX), a proximity labeling technology for subcellular #proteomics applied to primary #cilia. iAPEX uses an enzymatic cascade, in which a D-amino acid oxidase locally produces H2O2 to activate ascorbate peroxidase.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An enzymatic cascade enables sensitive and specific proximity labeling proteomics in challenging biological systems - Nature Communications
Proximity labeling allows proteomic mapping of subcellular structures. Here, Sroka et al. develop in situ APEX activation (iAPEX) to overcome limitations of labeling specificity and H2O2 toxicity, app...
www.nature.com
November 14, 2025 at 8:07 PM
Thrilled to share "in situ APEX activation" (iAPEX), a proximity labeling technology for subcellular #proteomics applied to primary #cilia. iAPEX uses an enzymatic cascade, in which a D-amino acid oxidase locally produces H2O2 to activate ascorbate peroxidase.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by UK Cilia and Centrosome Network
If you’re at #sfn25 you definitely don’t want to miss this nanosymposium on cilia, tomorrow from 1-4pm! Come learn about neuronal cilia, they do some pretty cool stuff!
Synapses may get all the glory, but join us cilia-philes for our @sfn.org Nanosymposium to learn about the role of cilia in modulating brain activity, behavior, and development.
Sunday November 16th 1-4pm SDCC Room 25A. Thrilled to chair with @konjikusicmia.bsky.social - we'll see you there!
Sunday November 16th 1-4pm SDCC Room 25A. Thrilled to chair with @konjikusicmia.bsky.social - we'll see you there!
November 15, 2025 at 8:26 PM
If you’re at #sfn25 you definitely don’t want to miss this nanosymposium on cilia, tomorrow from 1-4pm! Come learn about neuronal cilia, they do some pretty cool stuff!
Reposted by UK Cilia and Centrosome Network
Reposted by UK Cilia and Centrosome Network
Very excited to share this one! Our comprehensive structure, genetics and biophysics dissection of which flagellar dyneins and other proteins are needed for flagella to beat and drive cells swimming behaviours: www.biorxiv.org/content/10.1...
November 8, 2025 at 8:42 AM
Very excited to share this one! Our comprehensive structure, genetics and biophysics dissection of which flagellar dyneins and other proteins are needed for flagella to beat and drive cells swimming behaviours: www.biorxiv.org/content/10.1...
Reposted by UK Cilia and Centrosome Network
Our special issue on ‘Cilia and Flagella’ is now out! Huge thanks to all (authors + reviewers) who contributed, and to our wonderful Guest Editors (@cilialab.bsky.social + @lottepedersen.bsky.social) for pulling it together.
Happy reading!
#cilia #flagella
journals.biologists.com/jcs/issue/13...
Happy reading!
#cilia #flagella
journals.biologists.com/jcs/issue/13...
Volume 138 Issue 20 | Journal of Cell Science | The Company of Biologists
Journal of Cell Science publishes cutting-edge science encompassing all aspects of cell biology. It is published by The Company of Biologists, a not-for-profit organisation.
journals.biologists.com
November 3, 2025 at 5:32 PM
Our special issue on ‘Cilia and Flagella’ is now out! Huge thanks to all (authors + reviewers) who contributed, and to our wonderful Guest Editors (@cilialab.bsky.social + @lottepedersen.bsky.social) for pulling it together.
Happy reading!
#cilia #flagella
journals.biologists.com/jcs/issue/13...
Happy reading!
#cilia #flagella
journals.biologists.com/jcs/issue/13...
Reposted by UK Cilia and Centrosome Network
Amanda Smith, Lawrence Ostrowski and colleagues find that lipid nanoparticle-encapsulated Dnai1 mRNA rescues ciliary activity in primary ciliary dyskinesia mouse cell models.
#JCSciliaSI
journals.biologists.com/jcs/article/...
#JCSciliaSI
journals.biologists.com/jcs/article/...
November 5, 2025 at 10:23 AM
Amanda Smith, Lawrence Ostrowski and colleagues find that lipid nanoparticle-encapsulated Dnai1 mRNA rescues ciliary activity in primary ciliary dyskinesia mouse cell models.
#JCSciliaSI
journals.biologists.com/jcs/article/...
#JCSciliaSI
journals.biologists.com/jcs/article/...
Reposted by UK Cilia and Centrosome Network
Laurence Wilson and Martin Bees use high-speed 3D holographic imaging to capture the flagellar beat of single algal cells, revealing changes in the ‘handedness’ of the flagellar shapes at different points in their cycle.
#JCSciliaSI
journals.biologists.com/jcs/article/...
#JCSciliaSI
journals.biologists.com/jcs/article/...
November 6, 2025 at 9:05 AM
Laurence Wilson and Martin Bees use high-speed 3D holographic imaging to capture the flagellar beat of single algal cells, revealing changes in the ‘handedness’ of the flagellar shapes at different points in their cycle.
#JCSciliaSI
journals.biologists.com/jcs/article/...
#JCSciliaSI
journals.biologists.com/jcs/article/...
Reposted by UK Cilia and Centrosome Network
Exciting project!
Hello mosquito 🦟 and microbiota 🧫 🦠 aficionados, we are looking for a postdoc to join our team (Saleh's lab @salehlabparis.bsky.social at Institut Pasteur @pasteur.fr ) to investigate the interplay between the mosquito, its microbiota, and arboviruses. More information here 👇
November 7, 2025 at 11:10 AM
Exciting project!
Reposted by UK Cilia and Centrosome Network
This was a fun chat. Thanks @jcellsci.bsky.social for featuring me and spotlighting our work.
Check out the special issue on Cilia and Flagella journals.biologists.com/jcs/issue/13....
We have an article on Axonemal Dynein Assembly Factors (DNAAFs) which may be useful for the field.
Check out the special issue on Cilia and Flagella journals.biologists.com/jcs/issue/13....
We have an article on Axonemal Dynein Assembly Factors (DNAAFs) which may be useful for the field.
October 31, 2025 at 8:44 AM
This was a fun chat. Thanks @jcellsci.bsky.social for featuring me and spotlighting our work.
Check out the special issue on Cilia and Flagella journals.biologists.com/jcs/issue/13....
We have an article on Axonemal Dynein Assembly Factors (DNAAFs) which may be useful for the field.
Check out the special issue on Cilia and Flagella journals.biologists.com/jcs/issue/13....
We have an article on Axonemal Dynein Assembly Factors (DNAAFs) which may be useful for the field.
Reposted by UK Cilia and Centrosome Network
📣 Here it is — our overview on ciliary proteomics! Great discussions and writing with @mick-lab.bsky.social and Ronald Roepman 🙏🙏
Hope we didn’t miss anything important - apologies if we did!
#cilia #ciliopathies #proteomics
@theracilproject.bsky.social @for5547.bsky.social
tinyurl.com/yc8ztn5v
Hope we didn’t miss anything important - apologies if we did!
#cilia #ciliopathies #proteomics
@theracilproject.bsky.social @for5547.bsky.social
tinyurl.com/yc8ztn5v
Advances in ciliary proteomics – towards cracking the hidden proteome code of cilia
Summary: This Review explores proteomic strategies for investigating cilia, tracing the evolution from early discoveries to recent advancements enabled by proximity labeling techniques.
journals.biologists.com
November 1, 2025 at 4:34 PM
📣 Here it is — our overview on ciliary proteomics! Great discussions and writing with @mick-lab.bsky.social and Ronald Roepman 🙏🙏
Hope we didn’t miss anything important - apologies if we did!
#cilia #ciliopathies #proteomics
@theracilproject.bsky.social @for5547.bsky.social
tinyurl.com/yc8ztn5v
Hope we didn’t miss anything important - apologies if we did!
#cilia #ciliopathies #proteomics
@theracilproject.bsky.social @for5547.bsky.social
tinyurl.com/yc8ztn5v
Reposted by UK Cilia and Centrosome Network
Great Science! Great food and great company in Oberbronn! Thank you to the organizers of the CFC meeting 2025! Thank you for all the fantastic talks & posters! + unbeatable morning runs! @club-cfc.bsky.social @bastinlab.bsky.social @alexbnmrh.bsky.social #cilia #flagella #centrosome #ciliopathies
October 25, 2025 at 2:42 PM
Great Science! Great food and great company in Oberbronn! Thank you to the organizers of the CFC meeting 2025! Thank you for all the fantastic talks & posters! + unbeatable morning runs! @club-cfc.bsky.social @bastinlab.bsky.social @alexbnmrh.bsky.social #cilia #flagella #centrosome #ciliopathies
Reposted by UK Cilia and Centrosome Network
Our Special Issue on Cilia and Flagella: from Basic Biology to Disease, guest edited by @cilialab.bsky.social and @lottepedersen.bsky.social, is building. We’ll be highlighting all the articles over the next couple of weeks. Follow along at #JCSciliaSI.
journals.biologists.com/jcs/issue/13...
journals.biologists.com/jcs/issue/13...
Volume 138 Issue 20 | Journal of Cell Science | The Company of Biologists
journals.biologists.com
October 27, 2025 at 10:30 AM
Our Special Issue on Cilia and Flagella: from Basic Biology to Disease, guest edited by @cilialab.bsky.social and @lottepedersen.bsky.social, is building. We’ll be highlighting all the articles over the next couple of weeks. Follow along at #JCSciliaSI.
journals.biologists.com/jcs/issue/13...
journals.biologists.com/jcs/issue/13...
Reposted by UK Cilia and Centrosome Network
Great issue! Bonus: includes Daniel's work on incorporation of tagged tubulin in flagella!
October 28, 2025 at 8:55 AM
Great issue! Bonus: includes Daniel's work on incorporation of tagged tubulin in flagella!
Reposted by UK Cilia and Centrosome Network
Thank you @bastinlab.bsky.social and Sylvie Friant for organising this amazing #cilia meeting! 🙏 So many interesting discussions, and not enough time! Just look at this beautiful venue... 🤩
October 15, 2025 at 8:07 PM
Thank you @bastinlab.bsky.social and Sylvie Friant for organising this amazing #cilia meeting! 🙏 So many interesting discussions, and not enough time! Just look at this beautiful venue... 🤩
Reposted by UK Cilia and Centrosome Network
Many thanks to all participants to the CFC2025 meeting last week for having made it such a vibrant experience! So much exciting research on #cilia
October 21, 2025 at 11:35 AM
Many thanks to all participants to the CFC2025 meeting last week for having made it such a vibrant experience! So much exciting research on #cilia
Reposted by UK Cilia and Centrosome Network
Special thanks to our keynote lectures for fantastic talks! @micromotility.bsky.social @mick-lab.bsky.social
October 21, 2025 at 11:39 AM
Special thanks to our keynote lectures for fantastic talks! @micromotility.bsky.social @mick-lab.bsky.social
Reposted by UK Cilia and Centrosome Network
Thank you to the organizers of the CFC meeting 2025 in Oberbronn! See you next year in Lyon! @club-cfc.bsky.social
October 15, 2025 at 2:03 PM
Thank you to the organizers of the CFC meeting 2025 in Oberbronn! See you next year in Lyon! @club-cfc.bsky.social
Reposted by UK Cilia and Centrosome Network
Synapses may get all the glory, but join us cilia-philes for our @sfn.org Nanosymposium to learn about the role of cilia in modulating brain activity, behavior, and development.
Sunday November 16th 1-4pm SDCC Room 25A. Thrilled to chair with @konjikusicmia.bsky.social - we'll see you there!
Sunday November 16th 1-4pm SDCC Room 25A. Thrilled to chair with @konjikusicmia.bsky.social - we'll see you there!
October 24, 2025 at 8:44 PM
Synapses may get all the glory, but join us cilia-philes for our @sfn.org Nanosymposium to learn about the role of cilia in modulating brain activity, behavior, and development.
Sunday November 16th 1-4pm SDCC Room 25A. Thrilled to chair with @konjikusicmia.bsky.social - we'll see you there!
Sunday November 16th 1-4pm SDCC Room 25A. Thrilled to chair with @konjikusicmia.bsky.social - we'll see you there!
Reposted by UK Cilia and Centrosome Network
🎆 Join us for an unmissable finale to 2025! 🎆 We're thrilled to bring our #cilia & #centrosome community together 25/11/2025 15:00-17:45 GMT! Our 53rd @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social e-symposium schedule is live: www.eventbrite.co.uk/e/bscb-genso... /1
October 21, 2025 at 6:11 PM
🎆 Join us for an unmissable finale to 2025! 🎆 We're thrilled to bring our #cilia & #centrosome community together 25/11/2025 15:00-17:45 GMT! Our 53rd @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social e-symposium schedule is live: www.eventbrite.co.uk/e/bscb-genso... /1
Reposted by UK Cilia and Centrosome Network
Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia.
Open access link below:
www.nature.com/articles/s41...
Here's a cool animated summary
Open access link below:
www.nature.com/articles/s41...
Here's a cool animated summary
September 29, 2025 at 7:09 PM
Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia.
Open access link below:
www.nature.com/articles/s41...
Here's a cool animated summary
Open access link below:
www.nature.com/articles/s41...
Here's a cool animated summary
Exciting new work on the activation mechanism of the dynein motors that power motile ciliary beating!
Happy to share the inaugural paper from the lab. We describe a molecular mechanism for the activation of outer dynein arm motors that power the vital motion of cilia.
Open access link below:
www.nature.com/articles/s41...
Here's a cool animated summary
Open access link below:
www.nature.com/articles/s41...
Here's a cool animated summary
September 29, 2025 at 7:23 PM
Exciting new work on the activation mechanism of the dynein motors that power motile ciliary beating!
