Colin Bingle
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colinbingle.bsky.social
Colin Bingle
@colinbingle.bsky.social
Ageing (recently retired) academic with an inherent interest in biology (biomedical, comparative, molecular).
No politics or sniping about the state of things but I can tell you
I cycle for cake.
Pinned
Forgot to add this... we did the C2C in a day. I was/am raising money in support of Sheffield's "Team Molly" in memory of Molly Midgley-Hellend. You can still reward my considerable efforts with your sponsorship. Thank you.
I am going to return my 🚴🏻‍♀️ back to my previous level for a while now.
So I posted these musings on BPIFB4 to a preprint server as I was not really sure what to do with them. They have been stuck in my head for too long. Let me know what you think?
www.preprints.org/manuscript/2...
www.preprints.org
November 21, 2025 at 10:06 AM
The Beginner's Guides are the most accessed content in The Biochemist. If you have a topic that you think might fit and better still if you would like to write one, then contact the editorial office.
Struggling to get your head around some fundamental techniques in biochemistry or wondering where to start developing your knowledge? Have a look at our easy-to-follow Beginner's Guide series in The Biochemist Journal for a wide variety of guides! 🧪 buff.ly/ZO4zyU4
November 20, 2025 at 10:23 AM
Reposted by Colin Bingle
We’re on our 3rd day of (v cold) strike today @sheffielducu.bsky.social @ucu.org.uk

HE is being dismantled by mgmt on eye watering salaries, whilst staff delivering teaching, research & admin are casualised, burnt out & forced out

Pls donate to our fighting fund if you can shorturl.at/EpeTe
Donate to the Sheffield UCU Industrial Action Solidarity Fund
What is the Sheffield UCU Industrial Action Solidarity Fund, and how to contribute.
shorturl.at
November 19, 2025 at 10:24 AM
An outstanding opportunity. @ukcilianetwork.bsky.social could amplify this (maybe they have)?
November 19, 2025 at 1:32 PM
Here's a great paper tracing the molecular evolution of the H5N1 avian influenza outbreak.

www.nature.com/articles/s41...
Ecology and spread of the North American H5N1 epizootic - Nature
The panzootic of highly pathogenic H5N1 since 2021 was driven by around nine introductions into the Atlantic and Pacific flyways, followed by rapid dissemination through wild migratory birds, primaril...
www.nature.com
November 19, 2025 at 9:02 AM
Reposted by Colin Bingle
I am on strike this week, in support of colleagues placed at risk of compulsory redundancy.

www.ucu.org.uk/article/1423...

If you a student and want to know more/how to support the strike, see here: ucu.group.shef.ac.uk/industrial-a...

@sheffielducu.bsky.social
November 17, 2025 at 9:21 AM
Reposted by Colin Bingle
Heartbroken to be on strike (again) - never an easy decision 👍 We cannot accept a university in which staff jobs, student education, and research progress are under threat by major (and financially unnecessary) change management processes. @sheffielducu.bsky.social #Sheffield #DigitalPicket
November 17, 2025 at 8:38 AM
Reposted by Colin Bingle
Solidarity with all my former colleagues @sheffielducu.bsky.social out on strike yet again after years of uncertainty and restructures due to shambolic management decisions.
November 17, 2025 at 9:08 AM
Reposted by Colin Bingle
@sheffielducu.bsky.social Do the University’s financial reports support the need to make job cuts? #DigitalPicket #Sheffield

t.co/pmTtz6x6kx
https://ucu.group.shef.ac.uk/campaigns/state-of-the-university-2024-25/financial-position-cuts/
t.co
November 17, 2025 at 9:02 AM
Reposted by Colin Bingle
@bmj.com has issued an expression of concern for a paper claiming stem cell therapy can reduce the risk of heart failure. The move comes after sleuths and scientists critiqued the “complete mismatch” between the study data and the article itself.
BMJ places expression of concern on heavily criticized stem cell paper
The BMJ has issued an expression of concern for a paper claiming stem cell therapy can reduce the risk of heart failure. The move comes after sleuths and scientists critiqued the “complete mismatch…
retractionwatch.com
November 12, 2025 at 9:33 PM
One of the things that academics should understand is that not only do professional societies offer you pathways to involvement in the shaping of the society and it's research objectives but that this can also be enjoyable as well.
I have had 20+ years of engagement with the Biochem Soc.
Sitting on our Council of Trustees, our Vice President, Prof. Richard Reece shared his experience in the role earlier this year #TrusteeWeek buff.ly/7nuQTgn
November 11, 2025 at 7:45 PM
Reposted by Colin Bingle
This #TrusteesWeek we thank all those who support us on our committees, boards and panels. Our vital work couldn't be possible without the dedication of these roles. Discover more: buff.ly/fxF03hX
November 4, 2025 at 11:00 AM
I am a little late on this paper (I am retired 😎) but this is really cool piece of work.

Marsupial single-cell transcriptomics identifies temporal diversity in mammalian developmental programs: Developmental Cell www.cell.com/developmenta...
Marsupial single-cell transcriptomics identifies temporal diversity in mammalian developmental programs
Menchero et al. generate a single-cell transcriptomic atlas in the opossum and show rapid progression of transcriptional programs in specific tissues relative to morphological landmarks. This shift in...
www.cell.com
November 3, 2025 at 1:40 PM
Reposted by Colin Bingle
Our Special Issue on Cilia and Flagella: from Basic Biology to Disease, guest edited by @cilialab.bsky.social‬ and @lottepedersen.bsky.social, is building. We’ll be highlighting all the articles over the next couple of weeks. Follow along at #JCSciliaSI.
journals.biologists.com/jcs/issue/13...
Volume 138 Issue 20 | Journal of Cell Science | The Company of Biologists
journals.biologists.com
October 27, 2025 at 10:30 AM
Reposted by Colin Bingle
🔊New preprint from our lab!

Zygotene cilia regulates meiosis, germ cell development, and fertility in zebrafish, mice, and humans

www.researchsquare.com/article/rs-7...
Zygotene cilia regulate meiosis, germ cell development and fertility in zebrafish, mice, and humans
Germ cells accurately organize their chromosomes through the program of meiosis to successfully generate haploid gametes for fertilization1. Chromosomal pairing, which is essential for homologous reco...
www.researchsquare.com
October 26, 2025 at 4:01 PM
Reposted by Colin Bingle
We've worked to advance the molecular biosciences for over 100 years. Believing in the open exchange of ideas is one of our founding beliefs, driving our activities. Discover more: buff.ly/bEZI5ct #OAWeek
October 24, 2025 at 12:00 PM
Reposted by Colin Bingle
We are looking for talented, inspirational #bioscientists to be put forward for our 2027 #BiochemAwards! Spare some time today and nominate deserving colleagues for one of our 12 available categories. Deadline for initial nominations is 3 November 2025. https://ow.ly/EhgJ50X9yQs
October 10, 2025 at 10:30 AM
Reposted by Colin Bingle
Showcasing her outstanding contributions to the field of oxidative signalling throughout her career so far, congratulations to Professor Christine Foyer, who receives the 2026 Biochemical Society Award for Sustained Excellence at our Plant Proteins meeting today!
October 22, 2025 at 5:01 PM
Reposted by Colin Bingle
Dr Juan Carlos De La Concepcion presented the 2026 Early Career Research Award Lecture on structure-guided approaches to engineer novel resistance against destructive plant pathogens — a major biotechnological milestone for agriculture! #PlantProteinsMeeting
October 22, 2025 at 4:20 PM
Reposted by Colin Bingle
Last year we spoke to Elfy Chiang who shared her experience and career path that lead to her being an illustrator, animator, and science communicator. Read more about her career in The Biochemist: https://ow.ly/yM1L50XcZmX
October 18, 2025 at 12:01 PM
Did you watch The Hack? I can't believe papers have gotten away with destroying lives for so long. That's why I've signed the petition, set up by Hugh Grant and other phone hacking victims, to demand fair, independent regulation. Join me: you.38degrees.org.uk/petitions/a-...
A Free Press, Not a Free Pass – It's Time for Fair Regulation
For too long, the UK press have bullied people, harassed grieving families, and destroyed lives, all to sell papers. We’ve all seen the heartbreaking consequences. They’ve hacked phones, listened to ...
you.38degrees.org.uk
October 9, 2025 at 5:11 PM
Reposted by Colin Bingle
Great day to post a ballot (when isn't it?!) The announcement of more potential restructures during the ballot period shows just how shameless Uni of Sheffield management is! It's so important everyone votes in our local dispute to save jobs @sheffielducu.bsky.social
September 20, 2025 at 2:06 PM
I am delighted to see this amazing collaborative paper out in press. Using gene edited human ES cells differentiated into airway epithelium to uncover a novel role for MCIDAS in multiciliogenesis.
www.cell.com/cell-reports...
Nuclear-cytoplasmic translocation of MCIDAS couples transcription with massive de novo centriole biogenesis in multiciliated cells
How multiciliated cells (MCCs) generate hundreds of centrioles for multiciliation has remained an unresolved problem in cell biology. Lu et al. show that the MCC “master” transcriptional regulator, MC...
www.cell.com
September 22, 2025 at 3:20 PM
I will be very interested to see how they manage to save £3-4 million from the staff budget in ‪@fohsheffield.bsky.social and still offer "research led teaching"
Who will do the teaching? Who will do the research? Our last FVP said anyone could teach medical students. It may come to that?
September 15, 2025 at 9:14 AM