Congratulations to @sofiram.bsky.social and @artemiskorovesi.bsky.social on our last paper about the role of Sox8 in #xenopus #gastrulation
A link to the whole paper is here www.embopress.org/doi/full/10....
A link to the whole paper is here www.embopress.org/doi/full/10....
Sox8 is essential for vertebrate gastrulation | EMBO reports
imageimageThe use of CRISPR Cas7-11 uncovers a role for sox8 in Xenopus gastrulation as a regulator of Wnt signaling. sox8 downregulation in the ventrolateral mesoderm disrupts blastopore closure and...
www.embopress.org
November 10, 2025 at 1:57 PM
Congratulations to @sofiram.bsky.social and @artemiskorovesi.bsky.social on our last paper about the role of Sox8 in #xenopus #gastrulation
A link to the whole paper is here www.embopress.org/doi/full/10....
A link to the whole paper is here www.embopress.org/doi/full/10....
November 10, 2025 at 1:57 PM
🐸 Xenopus laevis 💚 The frog that shaped modern developmental biology! ✨ Xenopus embryos have revealed how the body axis forms, cells choose their fate, and tissues self-organize during early development 📹 Video by Bioquest Sudio and Xenbase #ModelMonday #DevBio
November 3, 2025 at 8:01 PM
🐸 Xenopus laevis 💚 The frog that shaped modern developmental biology! ✨ Xenopus embryos have revealed how the body axis forms, cells choose their fate, and tissues self-organize during early development 📹 Video by Bioquest Sudio and Xenbase #ModelMonday #DevBio
I'm a little achy, feverish and listless from a Covid vax, so I'm just processing photos tonight. For #FrogFriday here's an African Clawed Frog (Xenopus laevis), observed in SE Free State, South Africa. Note the upturned eyes, perfect for laying in shallow water. #herps #frogs #NaturePhotography 🌿
November 8, 2025 at 2:01 AM
I'm a little achy, feverish and listless from a Covid vax, so I'm just processing photos tonight. For #FrogFriday here's an African Clawed Frog (Xenopus laevis), observed in SE Free State, South Africa. Note the upturned eyes, perfect for laying in shallow water. #herps #frogs #NaturePhotography 🌿
#xenopus 🐸❤️
🐸 Xenopus laevis 💚 The frog that shaped modern developmental biology! ✨ Xenopus embryos have revealed how the body axis forms, cells choose their fate, and tissues self-organize during early development 📹 Video by Bioquest Sudio and Xenbase #ModelMonday #DevBio
November 3, 2025 at 8:07 PM
#xenopus 🐸❤️
@natmosqueda.bsky.social, @psutton54.bsky.social and @brownlee.bsky.social @stonybrooku.bsky.social discover that importin α plays a regulatory role in ciliogenesis and cilia length with implications for Xenopus nephrogenesis.
#JCSciliaSI
journals.biologists.com/jcs/article/...
#JCSciliaSI
journals.biologists.com/jcs/article/...
November 4, 2025 at 10:07 AM
@natmosqueda.bsky.social, @psutton54.bsky.social and @brownlee.bsky.social @stonybrooku.bsky.social discover that importin α plays a regulatory role in ciliogenesis and cilia length with implications for Xenopus nephrogenesis.
#JCSciliaSI
journals.biologists.com/jcs/article/...
#JCSciliaSI
journals.biologists.com/jcs/article/...
En les jornades @pnbbisciii.bsky.social també es va presentar el projecte #ASSET, eines digitals per a la gestió i l'intercanvi de mostres d'animals d'investigació.
Projecte internacional amb participació #CCiTUB @ub.edu
amb l'objectiu de contribuir a les #3R i garantir un ús ètic i responsable.
Projecte internacional amb participació #CCiTUB @ub.edu
amb l'objectiu de contribuir a les #3R i garantir un ús ètic i responsable.
November 3, 2025 at 11:06 AM
En les jornades @pnbbisciii.bsky.social també es va presentar el projecte #ASSET, eines digitals per a la gestió i l'intercanvi de mostres d'animals d'investigació.
Projecte internacional amb participació #CCiTUB @ub.edu
amb l'objectiu de contribuir a les #3R i garantir un ús ètic i responsable.
Projecte internacional amb participació #CCiTUB @ub.edu
amb l'objectiu de contribuir a les #3R i garantir un ús ètic i responsable.
Adding insult to injury, they go on to say that Arabidopsis thaliana COULD be considered an important model too... but not really. "Seats are limited", and how important is food really??
#PlantScience #PlantBlindness
#PlantScience #PlantBlindness
October 24, 2025 at 8:12 AM
Adding insult to injury, they go on to say that Arabidopsis thaliana COULD be considered an important model too... but not really. "Seats are limited", and how important is food really??
#PlantScience #PlantBlindness
#PlantScience #PlantBlindness
Ran et al. generated a retinal regeneration model and a tumor model using targeted integration in X. tropicalis (PNAS). Kagawa et al. provide a step-by-step protocol for knock-in targeted integration in X. laevis (DGD). www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
October 21, 2025 at 10:18 PM
Ran et al. generated a retinal regeneration model and a tumor model using targeted integration in X. tropicalis (PNAS). Kagawa et al. provide a step-by-step protocol for knock-in targeted integration in X. laevis (DGD). www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
Xenopus embryo growth cones move at 100-120 µm/hour 🏎️ doi.org/10.1083/jcb....
Scale bar below if 10 µm and total time is 11 minutes.That's about 2 times the speed of the fastest cell in the 2013 Cell Race! (doi.org/10.1016/j.cu...)
Scale bar below if 10 µm and total time is 11 minutes.That's about 2 times the speed of the fastest cell in the 2013 Cell Race! (doi.org/10.1016/j.cu...)
October 16, 2025 at 12:04 PM
Xenopus embryo growth cones move at 100-120 µm/hour 🏎️ doi.org/10.1083/jcb....
Scale bar below if 10 µm and total time is 11 minutes.That's about 2 times the speed of the fastest cell in the 2013 Cell Race! (doi.org/10.1016/j.cu...)
Scale bar below if 10 µm and total time is 11 minutes.That's about 2 times the speed of the fastest cell in the 2013 Cell Race! (doi.org/10.1016/j.cu...)
Cold Spring Harbor Laboratory Course - Cell & Developmental Biology of Xenopus: Gene Discovery & Disease, April 7 - 21, 2026. Application Deadline: January 16, 2026 xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
October 14, 2025 at 9:24 PM
Cold Spring Harbor Laboratory Course - Cell & Developmental Biology of Xenopus: Gene Discovery & Disease, April 7 - 21, 2026. Application Deadline: January 16, 2026 xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
#AxolotlActivism- you see frog I see #Xenopus- this could be a #DevelopmentalBiology uprising!! ✊✊✊ 'If I can't dance, I don't want to be part of your revolution.' Emma Goldman
October 10, 2025 at 7:54 PM
#AxolotlActivism- you see frog I see #Xenopus- this could be a #DevelopmentalBiology uprising!! ✊✊✊ 'If I can't dance, I don't want to be part of your revolution.' Emma Goldman
Prof. Sir John Gurdon (1933-2025). It is with great sadness that I share the news of the death of a father of the Xenopus field, Professor Sir John Gurdon. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
October 8, 2025 at 2:38 PM
Prof. Sir John Gurdon (1933-2025). It is with great sadness that I share the news of the death of a father of the Xenopus field, Professor Sir John Gurdon. www.xenbase.org/xenbase/doNe... #science #devbio #xenopus #frogs
Declaring that he thought he might tell our distinguished guest something about South Africa he didn't know. He then proceeded to talk for what in my memory was quite some time about the Xenopus toad. (3/n)
October 8, 2025 at 7:17 AM
Declaring that he thought he might tell our distinguished guest something about South Africa he didn't know. He then proceeded to talk for what in my memory was quite some time about the Xenopus toad. (3/n)
The Xenopus toad (wikipedia: 'a rather inactive creature') is native to sub-Saharan Africa is a common lab animal, used in the mid-20th century for pregnacy testing. Gurdon had cloned the toad (which sounded fabulous in his plummy accent) in the 1950s, the first time such event in a vertebrate (4/n)
October 8, 2025 at 7:19 AM
The Xenopus toad (wikipedia: 'a rather inactive creature') is native to sub-Saharan Africa is a common lab animal, used in the mid-20th century for pregnacy testing. Gurdon had cloned the toad (which sounded fabulous in his plummy accent) in the 1950s, the first time such event in a vertebrate (4/n)
great work from @teuneverts.bsky.social @inbo.be belgian #xenopus invasion is published still great needs for cross border collaboration @neobiota.pensoft.net @neobiota.bsky.social neobiota.pensoft.net/article/1503...
Mapping the northernmost transnational non-native population of Xenopus laevis using pooled eDNA sampling
Early-detection-rapid response (EDRR) programs are invaluable for managing incipient invasions, but require monitoring strategies that maximize search coverage and minimize costs. While environmental ...
neobiota.pensoft.net
October 8, 2025 at 7:47 AM
great work from @teuneverts.bsky.social @inbo.be belgian #xenopus invasion is published still great needs for cross border collaboration @neobiota.pensoft.net @neobiota.bsky.social neobiota.pensoft.net/article/1503...
Every figure in this paper uses HCR @hcrimaging.bsky.social
Such a game changing technique for studying gene expression #xenopus #neuralcrest
Such a game changing technique for studying gene expression #xenopus #neuralcrest
October 4, 2025 at 1:06 PM
Every figure in this paper uses HCR @hcrimaging.bsky.social
Such a game changing technique for studying gene expression #xenopus #neuralcrest
Such a game changing technique for studying gene expression #xenopus #neuralcrest
Researchers from #MPZPM and @mpiib-berlin.mpg.de have now compared the ratio of nuclear and cytoplasmic density in different organisms and come to a surprising conclusion: the cell nucleus in eukaryotes is less dense than the rest of the cell.
👉 mpzpm.mpg.de/news/news-de...
#Physics #Medicine
👉 mpzpm.mpg.de/news/news-de...
#Physics #Medicine
September 25, 2025 at 12:59 PM
Researchers from #MPZPM and @mpiib-berlin.mpg.de have now compared the ratio of nuclear and cytoplasmic density in different organisms and come to a surprising conclusion: the cell nucleus in eukaryotes is less dense than the rest of the cell.
👉 mpzpm.mpg.de/news/news-de...
#Physics #Medicine
👉 mpzpm.mpg.de/news/news-de...
#Physics #Medicine
9/12
And this isn’t just a fringe hypothesis: eg. fish pigment cells and Xenopus neural crest cells are already known to use such mechanisms to self-pattern.
Mesenchymal collectives can even...
And this isn’t just a fringe hypothesis: eg. fish pigment cells and Xenopus neural crest cells are already known to use such mechanisms to self-pattern.
Mesenchymal collectives can even...
September 24, 2025 at 1:06 PM
9/12
And this isn’t just a fringe hypothesis: eg. fish pigment cells and Xenopus neural crest cells are already known to use such mechanisms to self-pattern.
Mesenchymal collectives can even...
And this isn’t just a fringe hypothesis: eg. fish pigment cells and Xenopus neural crest cells are already known to use such mechanisms to self-pattern.
Mesenchymal collectives can even...
Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!
September 23, 2025 at 7:39 PM
Are you interested on how regenerating tissues transit between stages? Am sharing here our work showing that during #Xenopus tail regeneration, tissue stiffening activates a Piezo1-Yap1 mechanosensitive cascade to allow wounded epithelia to transit into regenerative states!
Finally, our work reveals a hidden mechanical state of regeneration where tissue stiffening instruct cells to transit into regenerative states...
Far from perfect but always looking forward to hearing from you #Regeneration #Mechanobiology #Piezo1 #Yap1 #Xenopus #FrogPower #Morphogenesis
Far from perfect but always looking forward to hearing from you #Regeneration #Mechanobiology #Piezo1 #Yap1 #Xenopus #FrogPower #Morphogenesis
September 23, 2025 at 7:39 PM
Finally, our work reveals a hidden mechanical state of regeneration where tissue stiffening instruct cells to transit into regenerative states...
Far from perfect but always looking forward to hearing from you #Regeneration #Mechanobiology #Piezo1 #Yap1 #Xenopus #FrogPower #Morphogenesis
Far from perfect but always looking forward to hearing from you #Regeneration #Mechanobiology #Piezo1 #Yap1 #Xenopus #FrogPower #Morphogenesis
Our new paper is out in Dev Biol! 🎉 🐸🧬
We show #miR-196a directs #neural crest fate in #Xenopus by repressing immature neural #ectoderm — evidence #miRNAs can potentially drive, not just fine-tune, early patterning
👉 Read more here: doi.org/10.1016/j.yd...
@devbiol.bsky.social @biouea.bsky.social
We show #miR-196a directs #neural crest fate in #Xenopus by repressing immature neural #ectoderm — evidence #miRNAs can potentially drive, not just fine-tune, early patterning
👉 Read more here: doi.org/10.1016/j.yd...
@devbiol.bsky.social @biouea.bsky.social
September 16, 2025 at 9:17 AM
Our new paper is out in Dev Biol! 🎉 🐸🧬
We show #miR-196a directs #neural crest fate in #Xenopus by repressing immature neural #ectoderm — evidence #miRNAs can potentially drive, not just fine-tune, early patterning
👉 Read more here: doi.org/10.1016/j.yd...
@devbiol.bsky.social @biouea.bsky.social
We show #miR-196a directs #neural crest fate in #Xenopus by repressing immature neural #ectoderm — evidence #miRNAs can potentially drive, not just fine-tune, early patterning
👉 Read more here: doi.org/10.1016/j.yd...
@devbiol.bsky.social @biouea.bsky.social
Joshua York of Northwestern University will kick off the #SDBPostdocSeminar with his talk "Shared features of blastula and neural crest stem cells evolved at the base of vertebrates" Image: Images of Xenopus (left) and lamprey (right) larvae
March 13, 2025 at 12:58 AM
Joshua York of Northwestern University will kick off the #SDBPostdocSeminar with his talk "Shared features of blastula and neural crest stem cells evolved at the base of vertebrates" Image: Images of Xenopus (left) and lamprey (right) larvae
Honestly xenopus eggs sound more appealing to me. I've never liked those chia seeds...
March 24, 2025 at 12:37 PM
Honestly xenopus eggs sound more appealing to me. I've never liked those chia seeds...
Proud to share our work spear-headed by PhD student Tommy Sroka with major contributions by #xenopus expert Kerstin Feistel.
Our iAPEX #ProximityLabeling method for #MassSpec based subcellular #proteomics works by locally generating H2O2 using a D-amino acid oxidase that activates APEX2 in situ.
Our iAPEX #ProximityLabeling method for #MassSpec based subcellular #proteomics works by locally generating H2O2 using a D-amino acid oxidase that activates APEX2 in situ.
iAPEX: Improved APEX-based proximity labeling for subcellular proteomics using an enzymatic reaction cascade
Ascorbate peroxidase (APEX) is a versatile labeling enzyme used for live-cell proteomics at high spatial and temporal resolution. However, toxicity of its substrate hydrogen peroxide and background la...
www.biorxiv.org
January 11, 2025 at 7:51 PM
Proud to share our work spear-headed by PhD student Tommy Sroka with major contributions by #xenopus expert Kerstin Feistel.
Our iAPEX #ProximityLabeling method for #MassSpec based subcellular #proteomics works by locally generating H2O2 using a D-amino acid oxidase that activates APEX2 in situ.
Our iAPEX #ProximityLabeling method for #MassSpec based subcellular #proteomics works by locally generating H2O2 using a D-amino acid oxidase that activates APEX2 in situ.