Tristan Rodriguez
@tristanrodriguez72.bsky.social
Biomedical scientist working at Imperial on how cells communicate. With a passion for trying to understand the world around us.
Reposted by Tristan Rodriguez
Delighted that Ziqi Dong's PhD paper is out for all to read! Hypoxia is fundamental to normal development, and fascinating! Thanks to all of our co-authors including @jamesnathanlab.bsky.social @jellevda.bsky.social authors.elsevier.com/sd/article/S...
October 11, 2025 at 8:22 AM
Delighted that Ziqi Dong's PhD paper is out for all to read! Hypoxia is fundamental to normal development, and fascinating! Thanks to all of our co-authors including @jamesnathanlab.bsky.social @jellevda.bsky.social authors.elsevier.com/sd/article/S...
Reposted by Tristan Rodriguez
New blog post. In which I analyze the new HHMI announcement and what it means for the science publishing ecosystem openrxiv.org/preprint-man...
Preprint mandates gather momentum - openRxiv
By Richard Sever, PhD. Chief Science & Strategy Officer, openRxiv Preprints speed up science by enabling researchers to disseminate reports of new findings immediately. They also represent a simple wa...
openrxiv.org
October 6, 2025 at 6:53 PM
New blog post. In which I analyze the new HHMI announcement and what it means for the science publishing ecosystem openrxiv.org/preprint-man...
Reposted by Tristan Rodriguez
Meet the 2025 cohort of @dev-journal.bsky.social Pathway to Independence fellows
Read about the scientific visions of eight dev bio post-docs entering the academic job market
journals.biologists.com/dev/article/...
Read about the scientific visions of eight dev bio post-docs entering the academic job market
journals.biologists.com/dev/article/...
Pathway to Independence: a forecast for the future of developmental biology
ABSTRACT. In 2022, Development launched its Pathway to Independence (PI) programme, aimed at supporting postdocs as they transition to their first independent position. In 2025, we welcome our third c...
journals.biologists.com
October 1, 2025 at 6:15 AM
Meet the 2025 cohort of @dev-journal.bsky.social Pathway to Independence fellows
Read about the scientific visions of eight dev bio post-docs entering the academic job market
journals.biologists.com/dev/article/...
Read about the scientific visions of eight dev bio post-docs entering the academic job market
journals.biologists.com/dev/article/...
Reposted by Tristan Rodriguez
🪰 Calling all Drosophilists interested in nutrition…HolFast, Sebastian Sorge’s new chemically defined diet works really well. We’ve given some free HolFast aliquots to @vdrc-flies.bsky.social Please contact them directly if you fancy trying it out. Hurry while stocks last!
The HolFast holidic (chemically defined) diet for Drosophila, recently designed by @alexgouldlab.bsky.social, has wide applications in nutritional and metabolic studies of Drosophila development doi.org/10.1016/j.de.... Limited free samples distributed by the VDRC. See www.vdrc.at. #Drosophila
September 30, 2025 at 2:17 PM
🪰 Calling all Drosophilists interested in nutrition…HolFast, Sebastian Sorge’s new chemically defined diet works really well. We’ve given some free HolFast aliquots to @vdrc-flies.bsky.social Please contact them directly if you fancy trying it out. Hurry while stocks last!
Reposted by Tristan Rodriguez
Pathway to Independence – an interview with Joaquín Navajas Acedo.
In this interview, @mads100tist.bsky.social talks about about his research vision, zebrafish and the importance of community:
journals.biologists.com/dev/article/...
In this interview, @mads100tist.bsky.social talks about about his research vision, zebrafish and the importance of community:
journals.biologists.com/dev/article/...
August 15, 2025 at 3:47 PM
Pathway to Independence – an interview with Joaquín Navajas Acedo.
In this interview, @mads100tist.bsky.social talks about about his research vision, zebrafish and the importance of community:
journals.biologists.com/dev/article/...
In this interview, @mads100tist.bsky.social talks about about his research vision, zebrafish and the importance of community:
journals.biologists.com/dev/article/...
Reposted by Tristan Rodriguez
1/n Dear friends, in light of the current events in Palestine and to help spread awareness, a large number of filmmakers have made their FILMS about PALESTINE AVAILABLE FOR ONLINE FOR FREE
Below, we are sharing links to films that you can watch and share to spread our message to the world:
Below, we are sharing links to films that you can watch and share to spread our message to the world:
August 5, 2025 at 10:37 PM
1/n Dear friends, in light of the current events in Palestine and to help spread awareness, a large number of filmmakers have made their FILMS about PALESTINE AVAILABLE FOR ONLINE FOR FREE
Below, we are sharing links to films that you can watch and share to spread our message to the world:
Below, we are sharing links to films that you can watch and share to spread our message to the world:
Reposted by Tristan Rodriguez
Thrilled to share our work using live imaging to understand how Epiblast (future embryo proper) and Primitive Endoderm (future extraembryonic tissues) cell fates segregate in the preimplantation mouse embryo. Gargantuan effort led by amazing @rpkimyip.bsky.social, David Denberg and Denis Faerberg!
August 2, 2025 at 7:31 PM
Thrilled to share our work using live imaging to understand how Epiblast (future embryo proper) and Primitive Endoderm (future extraembryonic tissues) cell fates segregate in the preimplantation mouse embryo. Gargantuan effort led by amazing @rpkimyip.bsky.social, David Denberg and Denis Faerberg!
Reposted by Tristan Rodriguez
We wrote this introductory review on how concepts from dynamical systems can help us understand developmental biology, hope it’s useful to somebody! It was a lot of fun to put together, and great to collaborate with brilliant colleagues across theory and experiments
Introducing five concepts from dynamical systems to decode developmental regulatory mechanisms, have a read! @perez-carrasco.bsky.social @roederlab.bsky.social @mpipz.bsky.social This effort started in a morphogenesis meeting @kitp-ucsb.bsky.social in 2023. journals.biologists.com/dev/article/...
August 4, 2025 at 2:46 PM
We wrote this introductory review on how concepts from dynamical systems can help us understand developmental biology, hope it’s useful to somebody! It was a lot of fun to put together, and great to collaborate with brilliant colleagues across theory and experiments
Reposted by Tristan Rodriguez
New work with Saunders & Charras labs
Physical boundaries guide cell fate decisions during human trunk development
Reaction Diffusion model shows how geometry shapes biology with TBXT expression forming consistent domains regardless of colony size & shape
www.biorxiv.org/content/10.1...
Physical boundaries guide cell fate decisions during human trunk development
Reaction Diffusion model shows how geometry shapes biology with TBXT expression forming consistent domains regardless of colony size & shape
www.biorxiv.org/content/10.1...
Boundary constraints can determine pattern emergence
The robust patterning of cell fates during embryonic development requires precise coordination of signalling gradients within defined spatial constraints. Using a geometrically confined in vitro syste...
www.biorxiv.org
July 23, 2025 at 5:37 AM
New work with Saunders & Charras labs
Physical boundaries guide cell fate decisions during human trunk development
Reaction Diffusion model shows how geometry shapes biology with TBXT expression forming consistent domains regardless of colony size & shape
www.biorxiv.org/content/10.1...
Physical boundaries guide cell fate decisions during human trunk development
Reaction Diffusion model shows how geometry shapes biology with TBXT expression forming consistent domains regardless of colony size & shape
www.biorxiv.org/content/10.1...
Reposted by Tristan Rodriguez
Next time, consider submitting to Biology Open. Decision with reviews within 7 working days of submission journals.biologists.com/bio/pages/fa...
May 18, 2025 at 11:25 AM
Next time, consider submitting to Biology Open. Decision with reviews within 7 working days of submission journals.biologists.com/bio/pages/fa...
Reposted by Tristan Rodriguez
Brexit has never looked quite so daft
February 28, 2025 at 10:29 PM
Brexit has never looked quite so daft
Reposted by Tristan Rodriguez
Our next extraordinary biologist this week is Daniel Gorelick, current Editor-in-Chief of @biologyopen.bsky.social and Associate Professor at @bcmhouston.bsky.social, USA. To know more about Dan’s visions for BiO, read this Editorial: doi.org/10.1242/bio.....
#100biologists
#100biologists
February 27, 2025 at 11:30 AM
Our next extraordinary biologist this week is Daniel Gorelick, current Editor-in-Chief of @biologyopen.bsky.social and Associate Professor at @bcmhouston.bsky.social, USA. To know more about Dan’s visions for BiO, read this Editorial: doi.org/10.1242/bio.....
#100biologists
#100biologists
Reposted by Tristan Rodriguez
We pay our academic editors (we don't do special issues with guest editors). Beginning in April, we also pay peer reviewers @biologyopen.bsky.social details to be announced at #biologists100 bit.ly/4h1cmCC @biologists.bsky.social
February 26, 2025 at 10:14 PM
We pay our academic editors (we don't do special issues with guest editors). Beginning in April, we also pay peer reviewers @biologyopen.bsky.social details to be announced at #biologists100 bit.ly/4h1cmCC @biologists.bsky.social
Reposted by Tristan Rodriguez
EpiSci - Hi there! Our review “Mechanotransduction in stem cells” is finally published. With @carstenschulte4.bsky.social we provided a comprehensive picture, that aims to cover the whole mechanotransductive pathway from the cell microenvironment to the nucleus. 1/3 pubmed.ncbi.nlm.nih.gov/38729084/
May 13, 2024 at 12:22 PM
EpiSci - Hi there! Our review “Mechanotransduction in stem cells” is finally published. With @carstenschulte4.bsky.social we provided a comprehensive picture, that aims to cover the whole mechanotransductive pathway from the cell microenvironment to the nucleus. 1/3 pubmed.ncbi.nlm.nih.gov/38729084/
I very thoughtful and reflective piece.
I wrote some thoughts about why peer review matters
It shapes scientific standards, maintains field coherence & trains new researchers
Yes, it needs improvement—but it's the glue that holds scientific progress together
briscoelab.org/2024/12/11/i...
It shapes scientific standards, maintains field coherence & trains new researchers
Yes, it needs improvement—but it's the glue that holds scientific progress together
briscoelab.org/2024/12/11/i...
In Praise of Peer Review
As an Editor of the journal Development, I often hear complaints about peer review. We all know the problems – from lengthy review times to requests for seemingly unnecessary experiments. I a…
briscoelab.org
December 11, 2024 at 6:25 PM
I very thoughtful and reflective piece.
Reposted by Tristan Rodriguez
A postdoctoral position is available in my lab to study the subcellular organisation of signalling of the glucagon receptor family. For more information and to apply please click here: www.imperial.ac.uk/jobs/search-...
December 8, 2024 at 4:07 PM
A postdoctoral position is available in my lab to study the subcellular organisation of signalling of the glucagon receptor family. For more information and to apply please click here: www.imperial.ac.uk/jobs/search-...
An excellent opportunity to go to a great lab with a caring mentor.
We are recruiting a postdoctoral research associate! Have a look at the flyer and/or the links below and get in touch if you have any questions! And please, share widely!!
www.imperial.ac.uk/jobs/search-...
www.imperial.ac.uk/jobs/search-...
December 6, 2024 at 11:37 PM
An excellent opportunity to go to a great lab with a caring mentor.
Reposted by Tristan Rodriguez
Nice to see our latest review published in
@natrevmcb.bsky.social today – a collaborative exploration of mammalian extraembryonic development with @cwhanna.bsky.social for an invaluable epigenetic focus. @srinivas-lab.bsky.social
www.nature.com/articles/s41...
@natrevmcb.bsky.social today – a collaborative exploration of mammalian extraembryonic development with @cwhanna.bsky.social for an invaluable epigenetic focus. @srinivas-lab.bsky.social
www.nature.com/articles/s41...
Origin, fate and function of extraembryonic tissues during mammalian development - Nature Reviews Molecular Cell Biology
During mammalian embryogenesis, extraembryonic tissues are required for the patterning and morphogenesis of the embryo. This Review discusses how signalling networks and epigenetic modifications regul...
www.nature.com
December 4, 2024 at 4:03 PM
Nice to see our latest review published in
@natrevmcb.bsky.social today – a collaborative exploration of mammalian extraembryonic development with @cwhanna.bsky.social for an invaluable epigenetic focus. @srinivas-lab.bsky.social
www.nature.com/articles/s41...
@natrevmcb.bsky.social today – a collaborative exploration of mammalian extraembryonic development with @cwhanna.bsky.social for an invaluable epigenetic focus. @srinivas-lab.bsky.social
www.nature.com/articles/s41...
Very happy to share the latest preprint from the lab. We find that during cell competition, winners induce an increase in proline metabolism in loser cells, and this drives their elimination through repression of the integrated stress response.
biorxiv.org/cgi/content/...
biorxiv.org/cgi/content/...
Sensing of extracellular L-Proline availability by the integrated stress response determines the outcome of cell competition
Cell competition is a quality control acting from development to the adult that eliminates cells that are less-fit than their neighbours. How winner cells induce the elimination of losers during this ...
biorxiv.org
December 3, 2024 at 7:36 AM
Very happy to share the latest preprint from the lab. We find that during cell competition, winners induce an increase in proline metabolism in loser cells, and this drives their elimination through repression of the integrated stress response.
biorxiv.org/cgi/content/...
biorxiv.org/cgi/content/...
Reposted by Tristan Rodriguez
Essential reading for all is that serve as reviewers. Please help your authors as if they were in your lab. Make your reviews constructive.
Overly onerous reviews amount to blocking each others’ work. It slows progress and demoralizes junior investigators.
Let’s elevate, not crush, #DevBio
Overly onerous reviews amount to blocking each others’ work. It slows progress and demoralizes junior investigators.
Let’s elevate, not crush, #DevBio
New @dev-journal.bsky.social editorial
We know we have high standards - but we're committed to making publishing with us constructive
From clear revision guidance to limitations sections & transparent peer review, we're here to help you share your science
journals.biologists.com/dev/article/...
We know we have high standards - but we're committed to making publishing with us constructive
From clear revision guidance to limitations sections & transparent peer review, we're here to help you share your science
journals.biologists.com/dev/article/...
Constructive Critics: Development's approach to peer review
We're all familiar with complaints about peer review. Some think it's biased – editors (especially from ‘those’ journals) seem to have too much power to decide what gets published. It can be opaque – ...
journals.biologists.com
December 2, 2024 at 12:44 PM
Essential reading for all is that serve as reviewers. Please help your authors as if they were in your lab. Make your reviews constructive.
Overly onerous reviews amount to blocking each others’ work. It slows progress and demoralizes junior investigators.
Let’s elevate, not crush, #DevBio
Overly onerous reviews amount to blocking each others’ work. It slows progress and demoralizes junior investigators.
Let’s elevate, not crush, #DevBio
Reposted by Tristan Rodriguez
Happy to have the Srinivas lab on Bluesky!
Even our embryos are starting to feel a little festive in the Srinivas lab! We are excited to share our new bioRχiv pre-print – investigating the role of calcium in the early embryo
www.biorxiv.org/content/10.1...
Even our embryos are starting to feel a little festive in the Srinivas lab! We are excited to share our new bioRχiv pre-print – investigating the role of calcium in the early embryo
www.biorxiv.org/content/10.1...
November 18, 2024 at 4:44 PM
Happy to have the Srinivas lab on Bluesky!
Even our embryos are starting to feel a little festive in the Srinivas lab! We are excited to share our new bioRχiv pre-print – investigating the role of calcium in the early embryo
www.biorxiv.org/content/10.1...
Even our embryos are starting to feel a little festive in the Srinivas lab! We are excited to share our new bioRχiv pre-print – investigating the role of calcium in the early embryo
www.biorxiv.org/content/10.1...
Reposted by Tristan Rodriguez
Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism
The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.
doi.org
November 25, 2024 at 11:16 AM
Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
Reposted by Tristan Rodriguez
Hello #SciSky 🧪! We're the Node, a community site for developmental and stem cell biologists, hosted by @dev-journal.bsky.social
This is your site: once you’ve registered, you can share your blog post, job advert or event notice with the #DevBio and #StemCell community.
thenode.biologists.com
This is your site: once you’ve registered, you can share your blog post, job advert or event notice with the #DevBio and #StemCell community.
thenode.biologists.com
Homepage - the Node
Welcome to the Node The Node is a place to read, write and interact with a global community of developmental and stem cell biologists. This is your site:
thenode.biologists.com
November 26, 2024 at 7:56 AM
Hello #SciSky 🧪! We're the Node, a community site for developmental and stem cell biologists, hosted by @dev-journal.bsky.social
This is your site: once you’ve registered, you can share your blog post, job advert or event notice with the #DevBio and #StemCell community.
thenode.biologists.com
This is your site: once you’ve registered, you can share your blog post, job advert or event notice with the #DevBio and #StemCell community.
thenode.biologists.com
Reposted by Tristan Rodriguez
🚨Abstract deadline- 13th December! 🚨
Join us next March in Liverpool for our Spring Meeting, joined with the BSCB and part of the Biologists@100 @biologists.bsky.social 🎉 Not to be missed!
We have annual meetings grants! Next deadline is the 10th of Jan. +Info here : bsdb.org/membership/#...
Join us next March in Liverpool for our Spring Meeting, joined with the BSCB and part of the Biologists@100 @biologists.bsky.social 🎉 Not to be missed!
We have annual meetings grants! Next deadline is the 10th of Jan. +Info here : bsdb.org/membership/#...
November 25, 2024 at 9:13 PM
🚨Abstract deadline- 13th December! 🚨
Join us next March in Liverpool for our Spring Meeting, joined with the BSCB and part of the Biologists@100 @biologists.bsky.social 🎉 Not to be missed!
We have annual meetings grants! Next deadline is the 10th of Jan. +Info here : bsdb.org/membership/#...
Join us next March in Liverpool for our Spring Meeting, joined with the BSCB and part of the Biologists@100 @biologists.bsky.social 🎉 Not to be missed!
We have annual meetings grants! Next deadline is the 10th of Jan. +Info here : bsdb.org/membership/#...