Trevor Sorrells
@trevorsorrells.bsky.social
Assistant Professor, Yale | HHMI Freeman Hrabowski Scholar | Mosquito Behavior and Evolution | he/him 🏳️🌈
In case it wasn’t obvious, opinions are my own and do not reflect those of my employer
In case it wasn’t obvious, opinions are my own and do not reflect those of my employer
Undergraduates who are interested in summer research please consider the HHMI Cech Fellows Program. There are many great HHMI labs to choose from including ours!
Calling all rising juniors & seniors: Interested in biological or biomedical research? Applications for our ’26 Summer Undergraduate Research Experience Program are now open! Nine weeks, hands-on research, & mentorship from some of the nation’s top scientists — learn more: bit.ly/CechFellows
Summer Undergraduate Research Experience | HHMI
The Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders.
bit.ly
November 21, 2025 at 6:36 PM
Undergraduates who are interested in summer research please consider the HHMI Cech Fellows Program. There are many great HHMI labs to choose from including ours!
Reposted by Trevor Sorrells
people are actually very susceptible to just-so stories about human origins because listening to bullshit helped us survive on the savanna
fake evo-psych has cooked a lot of people's brains
November 18, 2025 at 1:48 AM
people are actually very susceptible to just-so stories about human origins because listening to bullshit helped us survive on the savanna
Reposted by Trevor Sorrells
What does mating look like when you only have a single shot at getting it right?
Very excited to share our work on an almost-invisible female control, rapidly evolving mating recognition systems, and species that break the rules and take over the world. IN MOSQUITOES>
Very excited to share our work on an almost-invisible female control, rapidly evolving mating recognition systems, and species that break the rules and take over the world. IN MOSQUITOES>
October 28, 2025 at 8:57 PM
What does mating look like when you only have a single shot at getting it right?
Very excited to share our work on an almost-invisible female control, rapidly evolving mating recognition systems, and species that break the rules and take over the world. IN MOSQUITOES>
Very excited to share our work on an almost-invisible female control, rapidly evolving mating recognition systems, and species that break the rules and take over the world. IN MOSQUITOES>
Reposted by Trevor Sorrells
🦟 We've just published the world's first head-to-toe single-cell atlas of the Aedes aegypti mosquito in @cp-cell.bsky.social!
The #MosquitoCellAtlas maps 69 cell types across 19 tissues, revealing surprising biology. Read it here:
shorturl.at/dJWT3
The #MosquitoCellAtlas maps 69 cell types across 19 tissues, revealing surprising biology. Read it here:
shorturl.at/dJWT3
A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito
A comprehensive single-nucleus RNA-seq atlas of >367,000 nuclei from male and female
Aedes aegypti mosquitoes reveals sexual dimorphism in sensory systems and brain cell
types and widespread co-expres...
www.cell.com
October 30, 2025 at 3:28 PM
🦟 We've just published the world's first head-to-toe single-cell atlas of the Aedes aegypti mosquito in @cp-cell.bsky.social!
The #MosquitoCellAtlas maps 69 cell types across 19 tissues, revealing surprising biology. Read it here:
shorturl.at/dJWT3
The #MosquitoCellAtlas maps 69 cell types across 19 tissues, revealing surprising biology. Read it here:
shorturl.at/dJWT3
Reposted by Trevor Sorrells
🦟 The mosquito is the most deadly animal in the world. The Mosquito Cell Atlas is an incredible new resource to help us understand more about their ability to transmit pathogens to humans.
Data is available on the UC Santa Cruz @genomebrowser.bsky.social at mosquito.cells.ucsc.edu
Data is available on the UC Santa Cruz @genomebrowser.bsky.social at mosquito.cells.ucsc.edu
October 30, 2025 at 4:45 PM
🦟 The mosquito is the most deadly animal in the world. The Mosquito Cell Atlas is an incredible new resource to help us understand more about their ability to transmit pathogens to humans.
Data is available on the UC Santa Cruz @genomebrowser.bsky.social at mosquito.cells.ucsc.edu
Data is available on the UC Santa Cruz @genomebrowser.bsky.social at mosquito.cells.ucsc.edu
Reposted by Trevor Sorrells
Excited to announce the final version of the Mosquito Cell Atlas is out now in @cellpress.bsky.social!! 🦟🩸
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito
A comprehensive single-nucleus RNA-seq atlas of >367,000 nuclei from male and female
Aedes aegypti mosquitoes reveals sexual dimorphism in sensory systems and brain cell
types and widespread co-expres...
www.cell.com
October 30, 2025 at 4:05 PM
Excited to announce the final version of the Mosquito Cell Atlas is out now in @cellpress.bsky.social!! 🦟🩸
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
There is SO much left to find & investigate in this dataset (& the rich biology of the Aedes aegypti mosquito)! We hope this helps scientists in many fields!
www.cell.com/cell/fulltex...
Mosquito cell atlas is now published! Congratulations to @nadavshai.bsky.social and @oliviagoldman.net and the many other collaborators that contributed to this resource. www.cell.com/cell/fulltex...
A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito
A comprehensive single-nucleus RNA-seq atlas of >367,000 nuclei from male and female
Aedes aegypti mosquitoes reveals sexual dimorphism in sensory systems and brain cell
types and widespread co-expres...
www.cell.com
October 30, 2025 at 3:18 PM
Mosquito cell atlas is now published! Congratulations to @nadavshai.bsky.social and @oliviagoldman.net and the many other collaborators that contributed to this resource. www.cell.com/cell/fulltex...
Reposted by Trevor Sorrells
doi.org/10.1126/scie...
This seems rad: overexpressing FruM in a set of proboscis-motorneuron-projecting neurons makes melanogaster males add food-sharing to their courtship repertoire.
It is fascinating to see evolutionary shifts in behavior be tied so concretely to shifts in brain development!
This seems rad: overexpressing FruM in a set of proboscis-motorneuron-projecting neurons makes melanogaster males add food-sharing to their courtship repertoire.
It is fascinating to see evolutionary shifts in behavior be tied so concretely to shifts in brain development!
Cross-species implementation of an innate courtship behavior by manipulation of the sex-determinant gene
In accepting a courting male, Drosophila subobscura females require nuptial gift giving in which a male gives regurgitated crop contents to her mouth to mouth. No similar behavior is found in D. melan...
doi.org
October 20, 2025 at 2:39 AM
doi.org/10.1126/scie...
This seems rad: overexpressing FruM in a set of proboscis-motorneuron-projecting neurons makes melanogaster males add food-sharing to their courtship repertoire.
It is fascinating to see evolutionary shifts in behavior be tied so concretely to shifts in brain development!
This seems rad: overexpressing FruM in a set of proboscis-motorneuron-projecting neurons makes melanogaster males add food-sharing to their courtship repertoire.
It is fascinating to see evolutionary shifts in behavior be tied so concretely to shifts in brain development!
Reposted by Trevor Sorrells
Excited to share our new #biorxivpreprint
We discovered that the fruit fly #drosophila erecta requires food odor to mate and arousal is further enhanced by social group motion.
Cross-species analysis of brain activity reveals a novel gate evolved from within a conserved circuit
shorturl.at/gGYm7
We discovered that the fruit fly #drosophila erecta requires food odor to mate and arousal is further enhanced by social group motion.
Cross-species analysis of brain activity reveals a novel gate evolved from within a conserved circuit
shorturl.at/gGYm7
October 16, 2025 at 6:34 AM
Excited to share our new #biorxivpreprint
We discovered that the fruit fly #drosophila erecta requires food odor to mate and arousal is further enhanced by social group motion.
Cross-species analysis of brain activity reveals a novel gate evolved from within a conserved circuit
shorturl.at/gGYm7
We discovered that the fruit fly #drosophila erecta requires food odor to mate and arousal is further enhanced by social group motion.
Cross-species analysis of brain activity reveals a novel gate evolved from within a conserved circuit
shorturl.at/gGYm7
A seminal study no doubt
October 8, 2025 at 12:00 AM
A seminal study no doubt
Reposted by Trevor Sorrells
Dark taxa are extremely diverse organisms that remain largely undescribed due to small size, subtle differences, & few experts.
Take this quiz to find out what you are - I'm a gall midge! whatdarktaxonareyou.static.domains/insect-quiz....
by @vivianfeng.bsky.social & @flyliceresearch.bsky.social
Take this quiz to find out what you are - I'm a gall midge! whatdarktaxonareyou.static.domains/insect-quiz....
by @vivianfeng.bsky.social & @flyliceresearch.bsky.social
September 23, 2025 at 12:36 PM
Dark taxa are extremely diverse organisms that remain largely undescribed due to small size, subtle differences, & few experts.
Take this quiz to find out what you are - I'm a gall midge! whatdarktaxonareyou.static.domains/insect-quiz....
by @vivianfeng.bsky.social & @flyliceresearch.bsky.social
Take this quiz to find out what you are - I'm a gall midge! whatdarktaxonareyou.static.domains/insect-quiz....
by @vivianfeng.bsky.social & @flyliceresearch.bsky.social
Reposted by Trevor Sorrells
@trevorsorrells.bsky.social seminar for @tamubiology.bsky.social
cues waft on the wind
#mosquito neurons light up
blood thirst wanes post-bite
#sciku #neuroscience #biology
cues waft on the wind
#mosquito neurons light up
blood thirst wanes post-bite
#sciku #neuroscience #biology
September 23, 2025 at 9:58 PM
@trevorsorrells.bsky.social seminar for @tamubiology.bsky.social
cues waft on the wind
#mosquito neurons light up
blood thirst wanes post-bite
#sciku #neuroscience #biology
cues waft on the wind
#mosquito neurons light up
blood thirst wanes post-bite
#sciku #neuroscience #biology
Reposted by Trevor Sorrells
🚨 Only 3 days left to register! 🚨
Yale postdocs, don’t miss the Oct 9th @kavliatyale.bsky.social Chalk Talk event, featuring tips by @schandralab.bsky.social & a mock talk by @trevorsorrells.bsky.social!
Register Today!👇
yalesurvey.ca1.qualtrics.com/jfe/form/SV_...
Yale postdocs, don’t miss the Oct 9th @kavliatyale.bsky.social Chalk Talk event, featuring tips by @schandralab.bsky.social & a mock talk by @trevorsorrells.bsky.social!
Register Today!👇
yalesurvey.ca1.qualtrics.com/jfe/form/SV_...
September 22, 2025 at 6:41 PM
🚨 Only 3 days left to register! 🚨
Yale postdocs, don’t miss the Oct 9th @kavliatyale.bsky.social Chalk Talk event, featuring tips by @schandralab.bsky.social & a mock talk by @trevorsorrells.bsky.social!
Register Today!👇
yalesurvey.ca1.qualtrics.com/jfe/form/SV_...
Yale postdocs, don’t miss the Oct 9th @kavliatyale.bsky.social Chalk Talk event, featuring tips by @schandralab.bsky.social & a mock talk by @trevorsorrells.bsky.social!
Register Today!👇
yalesurvey.ca1.qualtrics.com/jfe/form/SV_...
Reposted by Trevor Sorrells
📢New preprint on the impact of dengue virus genetic diversity on inhibition by Wolbachia 🦟🦠🧬
Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨
Key findings in thread below 👇
www.biorxiv.org/content/10.1...
Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨
Key findings in thread below 👇
www.biorxiv.org/content/10.1...
Heterogeneity in inhibition of genetically diverse dengue virus strains by Wolbachia
The release of Aedes aegypti mosquitoes transinfected with the virus-inhibiting Wolbachia bacterium has the potential to reduce the burden caused by dengue virus (DENV). However, the robustness of thi...
www.biorxiv.org
September 19, 2025 at 7:23 PM
📢New preprint on the impact of dengue virus genetic diversity on inhibition by Wolbachia 🦟🦠🧬
Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨
Key findings in thread below 👇
www.biorxiv.org/content/10.1...
Project led by Afeez Sodeinde, @emiliefinch.bsky.social, and @keli5734.bsky.social! ✨
Key findings in thread below 👇
www.biorxiv.org/content/10.1...
Reposted by Trevor Sorrells
Starting to accumulate quite a few species in the mosquito gallery:
Mosquitoes - Alex Wild
Mosquitoes comprise a large family, Culicidae, of slender, scale-covered flies found worldwide. We think of mosquitoes as voracious blood-feeders, but the primary food of adult mosquitoes is actually ...
www.alexanderwild.com
September 18, 2025 at 7:58 PM
Starting to accumulate quite a few species in the mosquito gallery:
Reposted by Trevor Sorrells
Our paper Genomic diversity of the African malaria vector Anopheles funestus was published in Science today! It features inversions, selection in action, museum specimens and putative new ecotypes. doi.org/10.1126/scie...
September 18, 2025 at 6:45 PM
Our paper Genomic diversity of the African malaria vector Anopheles funestus was published in Science today! It features inversions, selection in action, museum specimens and putative new ecotypes. doi.org/10.1126/scie...
Reposted by Trevor Sorrells
A bluetorial on NIH funding and out year commitments:
A historical perspective
A historical perspective
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
September 13, 2025 at 2:26 PM
A bluetorial on NIH funding and out year commitments:
A historical perspective
A historical perspective
Reposted by Trevor Sorrells
"The unknown is made up of small organisms, such as insects, mites, and crustaceans. These species are the nuts and bolts of ecosystems. And most of them have yet to be identified."
www.vox.com/down-to-eart...
www.vox.com/down-to-eart...
The search for Earth’s most mysterious creatures is turning up extraordinary results
We still haven’t documented 90 percent of animals on Earth
www.vox.com
September 5, 2025 at 9:38 AM
"The unknown is made up of small organisms, such as insects, mites, and crustaceans. These species are the nuts and bolts of ecosystems. And most of them have yet to be identified."
www.vox.com/down-to-eart...
www.vox.com/down-to-eart...
Reposted by Trevor Sorrells
I am thrilled to announce that I just opened my lab at New York University in @nyucns.bsky.social and Biology! Our work will explore the richness of animal behavior, dissecting the genetic and circuit mechanisms that shape its evolution.
September 4, 2025 at 5:13 PM
I am thrilled to announce that I just opened my lab at New York University in @nyucns.bsky.social and Biology! Our work will explore the richness of animal behavior, dissecting the genetic and circuit mechanisms that shape its evolution.
Reposted by Trevor Sorrells
🚨 🐜 is there a Bluesky starter pack for researchers who don’t study ants but who get lightheaded every time there’s an awesome ant paper? CC @mariusw.bsky.social @jrichardalbert.bsky.social www.nature.com/articles/s41...
One mother for two species via obligate cross-species cloning in ants - Nature
In a case of obligate cross-species cloning, female ants of Messor ibericus need to clone males of Messor structor to obtain sperm for producing the worker caste, resulting in males from the same moth...
www.nature.com
September 3, 2025 at 6:47 PM
🚨 🐜 is there a Bluesky starter pack for researchers who don’t study ants but who get lightheaded every time there’s an awesome ant paper? CC @mariusw.bsky.social @jrichardalbert.bsky.social www.nature.com/articles/s41...
Reposted by Trevor Sorrells
Reposted by Trevor Sorrells
New paper on the role of H3K4me3 at enhancers! We (led by Haoming Yu) used dCas9 epigenome editing to add H3K4me3 to intergenic enhancers. This was (1) sufficient to turn up transcription at open, active regions and (2) has no effect on target gene transcription. genesdev.cshlp.org/content/earl...
H3K4me3 amplifies transcription at intergenic active regulatory elements
A biweekly scientific journal publishing high-quality research in molecular biology and genetics, cancer biology, biochemistry, and related fields
genesdev.cshlp.org
August 20, 2025 at 1:29 AM
New paper on the role of H3K4me3 at enhancers! We (led by Haoming Yu) used dCas9 epigenome editing to add H3K4me3 to intergenic enhancers. This was (1) sufficient to turn up transcription at open, active regions and (2) has no effect on target gene transcription. genesdev.cshlp.org/content/earl...
Reposted by Trevor Sorrells
Morinaga, @agloriasoria.bsky.social @jsoghigian.bsky.social develop two de novo chromosome-scale genomes for Aedes aegypti formosus and A. mascarensis, finding extensive chromosomal rearrangements between major lineages of mosquitoes.
🔗 doi.org/10.1093/gbe/evaf142
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf142
#genome #evolution
From Macro to Micro: De Novo Genomes of Aedes Mosquitoes Enable Comparative Genomics Among Close and Distant Relatives
Abstract. The yellow fever mosquito (Aedes aegypti) is an organism of high medical importance because it is the primary vector for diseases such as yellow
doi.org
August 15, 2025 at 7:18 AM
Morinaga, @agloriasoria.bsky.social @jsoghigian.bsky.social develop two de novo chromosome-scale genomes for Aedes aegypti formosus and A. mascarensis, finding extensive chromosomal rearrangements between major lineages of mosquitoes.
🔗 doi.org/10.1093/gbe/evaf142
#genome #evolution
🔗 doi.org/10.1093/gbe/evaf142
#genome #evolution
Reposted by Trevor Sorrells
Who do I know that breeds or has access to Mudskippers? I have some questions! Rt appreciated 🧪
August 10, 2025 at 2:37 PM
Who do I know that breeds or has access to Mudskippers? I have some questions! Rt appreciated 🧪