UC Santa Cruz Genomics Institute
@ucscgenomics.bsky.social
Focusing the power of genomics to create a healthier world. Leader in pangenomics, conservation genomics, cancer genomics, pathogen genomics, and nanopore sequencing. Home of the UCSC Genome Browser, @ucscxena, UShER, Dockstore, and other high-power tools.
📢 Our project has received a generous $3K matching gift! Generous donors like you have already matched $2220 - give now to help us match the remaining $780 and DOUBLE YOUR IMPACT!
It's Giving Day!!! You can help support 🎗pediatric cancer research AND a "degree-defining experience" for undergraduates by:
💸 Donating to Treehouse Childhood Cancer Initiative
🗣 Sharing this post to spread the word!
🔗 🎁 bit.ly/give2treehouse
💸 Donating to Treehouse Childhood Cancer Initiative
🗣 Sharing this post to spread the word!
🔗 🎁 bit.ly/give2treehouse
November 6, 2025 at 1:38 AM
📢 Our project has received a generous $3K matching gift! Generous donors like you have already matched $2220 - give now to help us match the remaining $780 and DOUBLE YOUR IMPACT!
It's Giving Day!!! You can help support 🎗pediatric cancer research AND a "degree-defining experience" for undergraduates by:
💸 Donating to Treehouse Childhood Cancer Initiative
🗣 Sharing this post to spread the word!
🔗 🎁 bit.ly/give2treehouse
💸 Donating to Treehouse Childhood Cancer Initiative
🗣 Sharing this post to spread the word!
🔗 🎁 bit.ly/give2treehouse
November 5, 2025 at 12:32 PM
It's Giving Day!!! You can help support 🎗pediatric cancer research AND a "degree-defining experience" for undergraduates by:
💸 Donating to Treehouse Childhood Cancer Initiative
🗣 Sharing this post to spread the word!
🔗 🎁 bit.ly/give2treehouse
💸 Donating to Treehouse Childhood Cancer Initiative
🗣 Sharing this post to spread the word!
🔗 🎁 bit.ly/give2treehouse
Support diversity and excellence in STEM by giving to our Research Mentoring Internship (RMI) this Giving Day 🎁 Federal cuts to DEI grants have made your gifts VITAL to keeping this program alive. Please support student mentorship today: www.givecampus.com/schools/Univ...
November 5, 2025 at 12:30 PM
Support diversity and excellence in STEM by giving to our Research Mentoring Internship (RMI) this Giving Day 🎁 Federal cuts to DEI grants have made your gifts VITAL to keeping this program alive. Please support student mentorship today: www.givecampus.com/schools/Univ...
Reposted by UC Santa Cruz Genomics Institute
Can lab-grown brain tissue learn like #AI? 🧠🤖 @ucscgenomics.bsky.social researchers led by #BaskinEngineering prof Tal Sharf will explore whether brain organoids can learn from experience, respond to feedback, and solve tasks in real time. bit.ly/4howct5
Effort aims to uncover the learning and reasoning potential of brain organoids
The Braingeneers team will to test the ability of brain organoids to solve tasks in real time
bit.ly
October 22, 2025 at 7:37 PM
Can lab-grown brain tissue learn like #AI? 🧠🤖 @ucscgenomics.bsky.social researchers led by #BaskinEngineering prof Tal Sharf will explore whether brain organoids can learn from experience, respond to feedback, and solve tasks in real time. bit.ly/4howct5
Reposted by UC Santa Cruz Genomics Institute
😷 Ever had a stomach bug? New #BaskinEngineering research brings us one step closer to stopping one of its viral causes! Prof Rebecca DuBois's lab revealed how human astroviruses—a cause of the stomach bug—bind to human cells, paving the way for future therapies and vaccines. bit.ly/3JfDrqY
Researchers pinpoint target for treating virus that causes the stomach bug
New study reveals how human astroviruses bind to humans cells and paves the way for new therapies and vaccines
bit.ly
November 4, 2025 at 5:00 PM
😷 Ever had a stomach bug? New #BaskinEngineering research brings us one step closer to stopping one of its viral causes! Prof Rebecca DuBois's lab revealed how human astroviruses—a cause of the stomach bug—bind to human cells, paving the way for future therapies and vaccines. bit.ly/3JfDrqY
Reposted by UC Santa Cruz Genomics Institute
Creating brains in a lab doesn't have to be like Frankenstein this Halloween. 🧠👻
The Braingeneers team at the UC Santa Cruz Genomics Institute recently received a $1.9 million grant to grow miniature 3D brains from stem cells.
The Braingeneers team at the UC Santa Cruz Genomics Institute recently received a $1.9 million grant to grow miniature 3D brains from stem cells.
The challenge of creating brains in a lab
Lab-grown brains don’t have to inspire horror.
voxdotcom.visitlink.me
October 31, 2025 at 6:57 PM
Creating brains in a lab doesn't have to be like Frankenstein this Halloween. 🧠👻
The Braingeneers team at the UC Santa Cruz Genomics Institute recently received a $1.9 million grant to grow miniature 3D brains from stem cells.
The Braingeneers team at the UC Santa Cruz Genomics Institute recently received a $1.9 million grant to grow miniature 3D brains from stem cells.
🦟 The mosquito is the most deadly animal in the world. The Mosquito Cell Atlas is an incredible new resource to help us understand more about their ability to transmit pathogens to humans.
Data is available on the UC Santa Cruz @genomebrowser.bsky.social at mosquito.cells.ucsc.edu
Data is available on the UC Santa Cruz @genomebrowser.bsky.social at mosquito.cells.ucsc.edu
October 30, 2025 at 4:45 PM
🦟 The mosquito is the most deadly animal in the world. The Mosquito Cell Atlas is an incredible new resource to help us understand more about their ability to transmit pathogens to humans.
Data is available on the UC Santa Cruz @genomebrowser.bsky.social at mosquito.cells.ucsc.edu
Data is available on the UC Santa Cruz @genomebrowser.bsky.social at mosquito.cells.ucsc.edu
Reposted by UC Santa Cruz Genomics Institute
UCSC's Brooks Lab tool FLAIR is helping to rewrite the story of cancer research—pushing precision medicine closer to truly individualized care. Learn how: santacruzworks.org/n...
Genomics Rooftop Mixer: Mapping Gene Isoforms to Improve Treatment — Santa Cruz Works
Angela Brooks and her team are rewriting cancer research with FLAIR, a tool
that reveals hidden RNA isoforms driving tumor growth and drug
resistance—insights that could revolutionize precision medicine.
www.santacruzworks.org
October 25, 2025 at 12:01 AM
UCSC's Brooks Lab tool FLAIR is helping to rewrite the story of cancer research—pushing precision medicine closer to truly individualized care. Learn how: santacruzworks.org/n...
Reposted by UC Santa Cruz Genomics Institute
@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"
Scaling back DEI programmes and the loss of scientific talent
Nature Cell Biology - Programmes that support diversity, equity and inclusion (DEI) in science are under attack in the USA. Data indicate that diversity in the scientific workforce increases...
www.nature.com
October 23, 2025 at 4:36 PM
@joann-trejo.bsky.social, @marymunson4.bsky.social and I have a commentary in @natcellbio.nature.com on recent attacks on DEI in biomedical research: "If scientific research, especially biomedical research, is meant to serve everyone, then it requires that everyone has an opportunity to participate"
Researchers using vg - a new release is now available at github.com/vgteam/vg/re... 🎉
vg giraffe now has
🧬 Improved support for cyclic snarls
🧬 An experimental recombination-aware mode
vg giraffe now has
🧬 Improved support for cyclic snarls
🧬 An experimental recombination-aware mode
Release vg 1.69.0 - Bologna · vgteam/vg
Don't forget to mark the static binary executable:
chmod +x vg
Docker Image: quay.io/vgteam/vg:v1.69.0
Buildable Source Tarball: vg-v1.69.0.tar.gz
Includes source for vg and all submodules. Use th...
github.com
October 24, 2025 at 6:20 PM
Researchers using vg - a new release is now available at github.com/vgteam/vg/re... 🎉
vg giraffe now has
🧬 Improved support for cyclic snarls
🧬 An experimental recombination-aware mode
vg giraffe now has
🧬 Improved support for cyclic snarls
🧬 An experimental recombination-aware mode
Reposted by UC Santa Cruz Genomics Institute
Accurate somatic small variant discovery for multiple sequencing technologies with DeepSomatic - @ucscgenomics.bsky.social go.nature.com/4qa6m0d
Accurate somatic small variant discovery for multiple sequencing technologies with DeepSomatic - Nature Biotechnology
Somatic small variants in cancer genomes are identified in both short-read and long-read data.
go.nature.com
October 16, 2025 at 4:13 PM
Accurate somatic small variant discovery for multiple sequencing technologies with DeepSomatic - @ucscgenomics.bsky.social go.nature.com/4qa6m0d
Nobel laureate Carol Greider has been named an @americancancersoc.bsky.social Professor 🎉 Her work at @ucsantacruz.bsky.social aims to overcome longstanding barriers to new cancer treatments—understanding how telomere length is regulated and accurately measuring it.
🔗 news.ucsc.edu/2025/10/grei...
🔗 news.ucsc.edu/2025/10/grei...
Carol Greider receives American Cancer Society Professor Award
The award includes a grant that will support Greider's research that advances her Nobel-winning discovery of the DNA caps at the ends of chromosomes called telomeres
news.ucsc.edu
October 7, 2025 at 8:52 PM
Nobel laureate Carol Greider has been named an @americancancersoc.bsky.social Professor 🎉 Her work at @ucsantacruz.bsky.social aims to overcome longstanding barriers to new cancer treatments—understanding how telomere length is regulated and accurately measuring it.
🔗 news.ucsc.edu/2025/10/grei...
🔗 news.ucsc.edu/2025/10/grei...
Reposted by UC Santa Cruz Genomics Institute
Although kelp can be frustrating to get tangled in when you're going for a swim in the ocean, resilient kelp can actually safeguard California’s coasts, fisheries, and biodiversity against warming oceans. Learn how: santacruzworks.org/n...
Genomics Rooftop Mixer: Kelp and the Future of Our Oceans — Santa Cruz Works
Join us October 28 for the Genomics Rooftop Mixer, featuring Malin Pinsky’s
kelp genomics research. Discover how resilient kelp can safeguard
California’s coasts, fisheries, and biodiversity against warming oceans.
Science, community, and conservation meet.
www.santacruzworks.org
September 26, 2025 at 7:14 AM
Although kelp can be frustrating to get tangled in when you're going for a swim in the ocean, resilient kelp can actually safeguard California’s coasts, fisheries, and biodiversity against warming oceans. Learn how: santacruzworks.org/n...
A court ruling in favor of @ucsantacruz.bsky.social Genomics Institute associate Ed Geen's startup Astrea Forensics paves the way for whole-genome sequencing, a cutting-edge technique used on degraded DNA in fossilized remains, to be admitted as evidence in trials 🦴🔍 www.nature.com/articles/d41...
October 1, 2025 at 6:12 PM
A court ruling in favor of @ucsantacruz.bsky.social Genomics Institute associate Ed Geen's startup Astrea Forensics paves the way for whole-genome sequencing, a cutting-edge technique used on degraded DNA in fossilized remains, to be admitted as evidence in trials 🦴🔍 www.nature.com/articles/d41...
Reposted by UC Santa Cruz Genomics Institute
Please take a moment to tell us how you use the Genome Browser: surveymars.com/q/mnb...
Your feedback supports future improvements and our continued funding.
Your feedback supports future improvements and our continued funding.
UCSC Genome Browser User Satisfaction Survey | SurveyMars
I have posted a survey titled 'UCSC Genome Browser User Satisfaction Survey' on SurveyMars. Please help me by filling it out. Thank you very much!
surveymars.com
September 5, 2025 at 10:07 PM
Please take a moment to tell us how you use the Genome Browser: surveymars.com/q/mnb...
Your feedback supports future improvements and our continued funding.
Your feedback supports future improvements and our continued funding.
Reposted by UC Santa Cruz Genomics Institute
We are pleased to announce the release of the Developmental Disorders Genotype-to-Phenotype (DDG2P) track for hg19 and hg38. The DDG2P track displays genes associated with severe developmental disorders.
Learn more at:
genome.ucsc.edu/gold...
Learn more at:
genome.ucsc.edu/gold...
September 19, 2025 at 8:08 PM
We are pleased to announce the release of the Developmental Disorders Genotype-to-Phenotype (DDG2P) track for hg19 and hg38. The DDG2P track displays genes associated with severe developmental disorders.
Learn more at:
genome.ucsc.edu/gold...
Learn more at:
genome.ucsc.edu/gold...
Breakthrough disease treatments are being developed, but they need #NIH funding! @khmiga.bsky.social and Krizia Chambers joined #RallyForMedicalResearch on Capitol Hill to tell lawmakers how important federal funding is to their research.
🧪🔬 Message your lawmakers: news.ucsc.edu/2025/09/advo...
🧪🔬 Message your lawmakers: news.ucsc.edu/2025/09/advo...
September 23, 2025 at 3:45 PM
Breakthrough disease treatments are being developed, but they need #NIH funding! @khmiga.bsky.social and Krizia Chambers joined #RallyForMedicalResearch on Capitol Hill to tell lawmakers how important federal funding is to their research.
🧪🔬 Message your lawmakers: news.ucsc.edu/2025/09/advo...
🧪🔬 Message your lawmakers: news.ucsc.edu/2025/09/advo...
Scientists at @ucsc have built an automated platform to grow and monitor brain organoids (brain tissue in a dish) 24/7 🧠🤖. It captures neural activity missed by manual methods—boosting reproducibility & paving the way for breakthroughs in brain research.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
September 19, 2025 at 9:56 PM
Scientists at @ucsc have built an automated platform to grow and monitor brain organoids (brain tissue in a dish) 24/7 🧠🤖. It captures neural activity missed by manual methods—boosting reproducibility & paving the way for breakthroughs in brain research.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
📢 Announcing the AnVIL Data Explorer!
This tool makes it easier to access and reuse high-value datasets, including those that focus on specific diseases like Alzheimer’s, cancer, and rare genetic disorders. Over 280 datasets are already available, with more to come.
news.ucsc.edu/2025/08/new-...
This tool makes it easier to access and reuse high-value datasets, including those that focus on specific diseases like Alzheimer’s, cancer, and rare genetic disorders. Over 280 datasets are already available, with more to come.
news.ucsc.edu/2025/08/new-...
September 8, 2025 at 6:07 PM
📢 Announcing the AnVIL Data Explorer!
This tool makes it easier to access and reuse high-value datasets, including those that focus on specific diseases like Alzheimer’s, cancer, and rare genetic disorders. Over 280 datasets are already available, with more to come.
news.ucsc.edu/2025/08/new-...
This tool makes it easier to access and reuse high-value datasets, including those that focus on specific diseases like Alzheimer’s, cancer, and rare genetic disorders. Over 280 datasets are already available, with more to come.
news.ucsc.edu/2025/08/new-...
🧑🧬🐒 Are humans and chimps *really* 99% similar? New telomere-to-telomere (T2T) genomes and other sequencing advancements are helping scientists reveal more differences, primarily in the "non-coding" regions of DNA that turn genes on and off.
www.livescience.com/archaeology/...
www.livescience.com/archaeology/...
Do humans and chimps really share nearly 99% of their DNA?
The frequently cited 99% similarity between human and chimp DNA overlooks key differences in the genomes.
www.livescience.com
September 8, 2025 at 4:56 PM
🧑🧬🐒 Are humans and chimps *really* 99% similar? New telomere-to-telomere (T2T) genomes and other sequencing advancements are helping scientists reveal more differences, primarily in the "non-coding" regions of DNA that turn genes on and off.
www.livescience.com/archaeology/...
www.livescience.com/archaeology/...
🌎 The Earth BioGenome Project is proposing to sequence 150,000 species over 4 years--which means releasing 3,000 new genomes a month ‼️
We're proud to be participating in this effort to create a rich resource to inform conservation, ensure food security, and even advance medicine.
We're proud to be participating in this effort to create a rich resource to inform conservation, ensure food security, and even advance medicine.
🚀🧬🔥 Hot off the press — 2025!
Don’t miss this must-read publication: bit.ly/4mJwFb7
This groundbreaking paper sets the stage for Earth BioGenome Project Phase II — where EBP is gearing up to scale genome sequencing 10× faster than ever before! 🌍✨
Don’t miss this must-read publication: bit.ly/4mJwFb7
This groundbreaking paper sets the stage for Earth BioGenome Project Phase II — where EBP is gearing up to scale genome sequencing 10× faster than ever before! 🌍✨
September 5, 2025 at 6:21 PM
🌎 The Earth BioGenome Project is proposing to sequence 150,000 species over 4 years--which means releasing 3,000 new genomes a month ‼️
We're proud to be participating in this effort to create a rich resource to inform conservation, ensure food security, and even advance medicine.
We're proud to be participating in this effort to create a rich resource to inform conservation, ensure food security, and even advance medicine.
Reposted by UC Santa Cruz Genomics Institute
Congratulations to lab member Maria! Maria joined us this summer as an NHGRI GREAT scholar @ucscgenomics.bsky.social Within 8 weeks she learned new wet lab techniques, bioinformatics, and carried out independent research. Proud to share that she received an award for outstanding research poster.
August 16, 2025 at 1:52 PM
Congratulations to lab member Maria! Maria joined us this summer as an NHGRI GREAT scholar @ucscgenomics.bsky.social Within 8 weeks she learned new wet lab techniques, bioinformatics, and carried out independent research. Proud to share that she received an award for outstanding research poster.
Reposted by UC Santa Cruz Genomics Institute
Headed to #ASHG25?
Don’t miss HPRC’s workshop on the Human Pangenome: Data, Tools & Workflows.
📅 Oct 14 | 10AM–12PM
Learn how to access data & use pangenome tools!
www.ashg.org/product/ashg...
Don’t miss HPRC’s workshop on the Human Pangenome: Data, Tools & Workflows.
📅 Oct 14 | 10AM–12PM
Learn how to access data & use pangenome tools!
www.ashg.org/product/ashg...
ASHG 2025 Workshop: The Human Pangenome: Data, Tools, and Workflows
Introducing participants to the new Human Pangenome Reference, how samples were chosen to maximize variation, & technologies used to build the pangenome
www.ashg.org
August 20, 2025 at 4:20 PM
Headed to #ASHG25?
Don’t miss HPRC’s workshop on the Human Pangenome: Data, Tools & Workflows.
📅 Oct 14 | 10AM–12PM
Learn how to access data & use pangenome tools!
www.ashg.org/product/ashg...
Don’t miss HPRC’s workshop on the Human Pangenome: Data, Tools & Workflows.
📅 Oct 14 | 10AM–12PM
Learn how to access data & use pangenome tools!
www.ashg.org/product/ashg...
Reposted by UC Santa Cruz Genomics Institute
We are excited to announce the release of the MaveDB Experiment Heatmaps and Alignment track for hg38. Each heatmap shows the results of many small substitutions that were tested within a gene to examine their functional consequences.
Learn more at:
http://bit.ly/4lCIlLq
Learn more at:
http://bit.ly/4lCIlLq
August 21, 2025 at 10:11 PM
We are excited to announce the release of the MaveDB Experiment Heatmaps and Alignment track for hg38. Each heatmap shows the results of many small substitutions that were tested within a gene to examine their functional consequences.
Learn more at:
http://bit.ly/4lCIlLq
Learn more at:
http://bit.ly/4lCIlLq
Reposted by UC Santa Cruz Genomics Institute
Google AI Releases DeepPolisher: A New Deep Learning Tool that Improves the Accuracy of Genome Assemblies by Precisely Correcting Base-Level Errors
Google AI, in collaboration with the UC Santa Cruz Genomics Institute, has introduced DeepPolisher, a cutting-edge deep learning tool designed to…
Google AI, in collaboration with the UC Santa Cruz Genomics Institute, has introduced DeepPolisher, a cutting-edge deep learning tool designed to…
Google AI Releases DeepPolisher: A New Deep Learning Tool that Improves the Accuracy of Genome Assemblies by Precisely Correcting Base-Level Errors
Google AI, in collaboration with the UC Santa Cruz Genomics Institute, has introduced DeepPolisher, a cutting-edge deep learning tool designed to substantially improve the accuracy of genome assemblies by correcting base-level errors. Its notable efficacy was recently demonstrated in advancing the Human Pangenome Reference, a major milestone in genomics research. The Challenge of Accurate Genome Assembly A reference genome is an essential foundation for understanding genetic diversity, heredity, disease mechanisms, and evolutionary biology.
nexttech-news.com
August 8, 2025 at 7:02 PM
Google AI Releases DeepPolisher: A New Deep Learning Tool that Improves the Accuracy of Genome Assemblies by Precisely Correcting Base-Level Errors
Google AI, in collaboration with the UC Santa Cruz Genomics Institute, has introduced DeepPolisher, a cutting-edge deep learning tool designed to…
Google AI, in collaboration with the UC Santa Cruz Genomics Institute, has introduced DeepPolisher, a cutting-edge deep learning tool designed to…