Tinca JC Polderman
@tincatwin.bsky.social
Associate Professor | Behavior Genetics | Mental Health | Child and Adolescent Psychiatry | Amsterdam
Reposted by Tinca JC Polderman
Folks following the leucovorin & autism story should be aware of a ton of PubPeer activity on one of the major trials. Many inconsistencies, statistical concerns, etc raised.
pubpeer.com/publications...
pubpeer.com/publications...
PubPeer - Efficacy of oral folinic acid supplementation in children wi...
There are comments on PubPeer for publication: Efficacy of oral folinic acid supplementation in children with autism spectrum disorder: a randomized double-blind, placebo-controlled trial (2024)
pubpeer.com
October 16, 2025 at 5:00 PM
Folks following the leucovorin & autism story should be aware of a ton of PubPeer activity on one of the major trials. Many inconsistencies, statistical concerns, etc raised.
pubpeer.com/publications...
pubpeer.com/publications...
Reposted by Tinca JC Polderman
Great review on The Genetics of Human Handedness: Microtubules and Beyond www.cell.com/trends/genet... - handedness is such an interesting phenotype!
Genetics of human handedness: microtubules and beyond
Handedness (i.e., the preference to use either the left or the right hand for fine
motor tasks) is a widely investigated trait. Handedness heritability is consistently
estimated to be 25%. After decad...
www.cell.com
October 16, 2025 at 6:12 PM
Great review on The Genetics of Human Handedness: Microtubules and Beyond www.cell.com/trends/genet... - handedness is such an interesting phenotype!
Reposted by Tinca JC Polderman
The nature of the relation between mental well-being and ill-being
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The nature of the relation between mental well-being and ill-being - Nature Human Behaviour
Tamnes et al. explore the complex relationship between ill-being—including mental and behavioural disorders—and mental well-being.
www.nature.com
October 16, 2025 at 3:12 PM
The nature of the relation between mental well-being and ill-being
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Tinca JC Polderman
📣The National Institutes of Health (NIH) is accepting applications for Director of the National Institute of Mental Health (NIMH). Help us spread the word about this opportunity!
🔗Find more information here: hr.nih.gov/jobs/search/...
#jobopportunity #NIMH
🔗Find more information here: hr.nih.gov/jobs/search/...
#jobopportunity #NIMH
hr.nih.gov
September 11, 2025 at 5:34 PM
📣The National Institutes of Health (NIH) is accepting applications for Director of the National Institute of Mental Health (NIMH). Help us spread the word about this opportunity!
🔗Find more information here: hr.nih.gov/jobs/search/...
#jobopportunity #NIMH
🔗Find more information here: hr.nih.gov/jobs/search/...
#jobopportunity #NIMH
Reposted by Tinca JC Polderman
Confused writing is usually a symptom of confused thinking. As we struggle to clarify writing, we clarify our thoughts. AI writing aids rob us of that struggle, leaving clean-looking text and thoughts still confused for lack of inspection. Writing is not just a product; it is a diagnostic tool.
September 5, 2025 at 3:20 PM
Confused writing is usually a symptom of confused thinking. As we struggle to clarify writing, we clarify our thoughts. AI writing aids rob us of that struggle, leaving clean-looking text and thoughts still confused for lack of inspection. Writing is not just a product; it is a diagnostic tool.
So that is why I receive 10 review invitations per month, and it takes -by now- *years* to publish. Discouraging!
Academic authors, here's a peek into the black box of journal publishing from an journal editor if you can bear it:
September 7, 2025 at 6:37 AM
So that is why I receive 10 review invitations per month, and it takes -by now- *years* to publish. Discouraging!
Reposted by Tinca JC Polderman
If you want to know more about autism and the genetics of autism, feel free to visit:
tinyurl.com/hjyyrjtr
tinyurl.com/hjyyrjtr
Autism Spectrum Disorder – PGC
tinyurl.com
May 26, 2025 at 1:41 PM
If you want to know more about autism and the genetics of autism, feel free to visit:
tinyurl.com/hjyyrjtr
tinyurl.com/hjyyrjtr
Reposted by Tinca JC Polderman
(1/9) 📣 OUT NOW! 📣
So excited to share that our systematic review and meta-analysis on the autism polygenic score is now published in JAACAP Open @jaacapjournals.bsky.social.
doi.org/10.1016/j.ja...
A (long) thread of our main findings ⤵️
So excited to share that our systematic review and meta-analysis on the autism polygenic score is now published in JAACAP Open @jaacapjournals.bsky.social.
doi.org/10.1016/j.ja...
A (long) thread of our main findings ⤵️
Redirecting
doi.org
May 31, 2025 at 9:21 AM
(1/9) 📣 OUT NOW! 📣
So excited to share that our systematic review and meta-analysis on the autism polygenic score is now published in JAACAP Open @jaacapjournals.bsky.social.
doi.org/10.1016/j.ja...
A (long) thread of our main findings ⤵️
So excited to share that our systematic review and meta-analysis on the autism polygenic score is now published in JAACAP Open @jaacapjournals.bsky.social.
doi.org/10.1016/j.ja...
A (long) thread of our main findings ⤵️
Thanks to all co-authors for collaborating, it was a true pleasure!
(9/9) It was a great pleasure working on this with Morgan Morgan, Ilan Libedinsky, Chloe Austerberry, Sander Begeer, @dr-appie.bsky.social, @angelicaronald.bsky.social and @tincatwin.bsky.social
June 1, 2025 at 9:08 AM
Thanks to all co-authors for collaborating, it was a true pleasure!
Extremely proud of @mmdewit.bsky.social for leading this comprehensive study on the #autism #polygenic score. Check out the interactive tool to easily find the association with your phenotype of interest!
(1/9) 📣 OUT NOW! 📣
So excited to share that our systematic review and meta-analysis on the autism polygenic score is now published in JAACAP Open @jaacapjournals.bsky.social.
doi.org/10.1016/j.ja...
A (long) thread of our main findings ⤵️
So excited to share that our systematic review and meta-analysis on the autism polygenic score is now published in JAACAP Open @jaacapjournals.bsky.social.
doi.org/10.1016/j.ja...
A (long) thread of our main findings ⤵️
Redirecting
doi.org
June 1, 2025 at 9:02 AM
Extremely proud of @mmdewit.bsky.social for leading this comprehensive study on the #autism #polygenic score. Check out the interactive tool to easily find the association with your phenotype of interest!
Reposted by Tinca JC Polderman
We are currently looking for new collaborators with genotyping and autism data in order to increase our sample size for our next large-scale genome-wide meta-analyses of autism. Want to contribute? Contact us! 📩
pgc.unc.edu/for-research...
pgc.unc.edu/for-research...
Autism Working Group – PGC
pgc.unc.edu
May 14, 2025 at 12:49 PM
We are currently looking for new collaborators with genotyping and autism data in order to increase our sample size for our next large-scale genome-wide meta-analyses of autism. Want to contribute? Contact us! 📩
pgc.unc.edu/for-research...
pgc.unc.edu/for-research...
Reposted by Tinca JC Polderman
Our goal is to have 1000 SUFS Teach Ins across the US, by 9/30.
*GASP* 😮
We know, it's a big goal.
If you've received tax dollars for your science, you have a responsibility to inform *your* community what is at stake: public health, the economy, innovation, and America's global leadership.
*GASP* 😮
We know, it's a big goal.
If you've received tax dollars for your science, you have a responsibility to inform *your* community what is at stake: public health, the economy, innovation, and America's global leadership.
May 18, 2025 at 6:21 PM
Our goal is to have 1000 SUFS Teach Ins across the US, by 9/30.
*GASP* 😮
We know, it's a big goal.
If you've received tax dollars for your science, you have a responsibility to inform *your* community what is at stake: public health, the economy, innovation, and America's global leadership.
*GASP* 😮
We know, it's a big goal.
If you've received tax dollars for your science, you have a responsibility to inform *your* community what is at stake: public health, the economy, innovation, and America's global leadership.
Reposted by Tinca JC Polderman
The genetic basis of human height www.nature.com/articles/s41... (read free: rdcu.be/egGQf) 🧬🖥️🧪
April 7, 2025 at 9:30 AM
The genetic basis of human height www.nature.com/articles/s41... (read free: rdcu.be/egGQf) 🧬🖥️🧪
Reposted by Tinca JC Polderman
Visit our website to read the latest Letter from the ISPG President, J9. ispg.net/about-us/mes...
April 2, 2025 at 4:01 PM
Visit our website to read the latest Letter from the ISPG President, J9. ispg.net/about-us/mes...
Reposted by Tinca JC Polderman
In every civilization, people end up sorted into levels of socio-economic status (SES). We explore the history, present, and future of scientific research on the complicated relationship between SES and DNA in @naturehumbehav.bsky.social💰🧬🎓
Link: rdcu.be/efacK
Thread below 👇🏽
Link: rdcu.be/efacK
Thread below 👇🏽
March 26, 2025 at 11:16 AM
In every civilization, people end up sorted into levels of socio-economic status (SES). We explore the history, present, and future of scientific research on the complicated relationship between SES and DNA in @naturehumbehav.bsky.social💰🧬🎓
Link: rdcu.be/efacK
Thread below 👇🏽
Link: rdcu.be/efacK
Thread below 👇🏽
What a missed chance for @TU Delft. Congrats dr. Rachel Los!
Dissertation by Dr Rachel Los not only includes acknowledgements, but also .. anti-acknowledgements.
delta.tudelft.nl/en/article/a...
delta.tudelft.nl/en/article/a...
March 14, 2025 at 7:59 PM
What a missed chance for @TU Delft. Congrats dr. Rachel Los!
Reposted by Tinca JC Polderman
The overall silence of major professional scientific societies while all this goes on is also bewildering. By the time they forcefully speak up, much damage will already have been done. 🧪
The ad-hoc termination of training grants, PhD fellowships, and center grants at Columbia is catastrophic and sends a message.
The WH will:
* Seek revenge at all costs
* Destroy science & higher ed, if it can
* Risk lives, careers and the economy.
Rest assured: they will not stop w/Columbia
The WH will:
* Seek revenge at all costs
* Destroy science & higher ed, if it can
* Risk lives, careers and the economy.
Rest assured: they will not stop w/Columbia
March 11, 2025 at 6:01 PM
The overall silence of major professional scientific societies while all this goes on is also bewildering. By the time they forcefully speak up, much damage will already have been done. 🧪
Reposted by Tinca JC Polderman
Genetic counseling community - lots going on in the US that’s negatively impacting us, science/research, patients & communities. Genetic counseling support call Fri 3/14 at 1pm PT. Safe space (not affiliated w/ any org) to share and listen. If you need the link, DM me or @j9austin.bsky.social
March 11, 2025 at 8:35 PM
Genetic counseling community - lots going on in the US that’s negatively impacting us, science/research, patients & communities. Genetic counseling support call Fri 3/14 at 1pm PT. Safe space (not affiliated w/ any org) to share and listen. If you need the link, DM me or @j9austin.bsky.social
Reposted by Tinca JC Polderman
On the 10th of April, Renata Androvicova, @joellepasman.bsky.social and Karin Verweij will host a workshop on the genetics of sexual violence. Join in person or online to discuss the results of the study on the genetic overlap between sexual violence, reproductive traits, and psychiatric traits!
March 11, 2025 at 9:48 PM
On the 10th of April, Renata Androvicova, @joellepasman.bsky.social and Karin Verweij will host a workshop on the genetics of sexual violence. Join in person or online to discuss the results of the study on the genetic overlap between sexual violence, reproductive traits, and psychiatric traits!
Reposted by Tinca JC Polderman
The BGA meeting in Atlanta will now have a hybrid option! 🌍🎥 We've also reopened abstract submissions for 2 weeks, with a hard deadline of March 14, 2025. Join us in person or virtually for a fantastic meeting!
Register here: auth.oxfordabstracts.com?redirect=/st... #BGA2025
Register here: auth.oxfordabstracts.com?redirect=/st... #BGA2025
Oxford Abstracts
auth.oxfordabstracts.com
March 6, 2025 at 12:22 PM
The BGA meeting in Atlanta will now have a hybrid option! 🌍🎥 We've also reopened abstract submissions for 2 weeks, with a hard deadline of March 14, 2025. Join us in person or virtually for a fantastic meeting!
Register here: auth.oxfordabstracts.com?redirect=/st... #BGA2025
Register here: auth.oxfordabstracts.com?redirect=/st... #BGA2025
Reposted by Tinca JC Polderman
Have you ever wondered about nonlinearity in bivariate genetic associations? Or wondered whether global estimators like genetic correlations tell the full story about the relationship between two phenotypes, then check out @michelnivard.bsky.social thread on some work we’ve been doing to model this.
🚨NEW PAPER! Together with Wuno Akingbuwa (@wonuola.bsky.social) we developed a way to estimate non-linear genetic correlations. It didnt sit well with us that known non-linear relations (e.g. BMI and MDD with a famous U shaped ) are poorly captured in statistical genetics. 🧵
www.biorxiv.org
February 17, 2025 at 12:18 PM
Have you ever wondered about nonlinearity in bivariate genetic associations? Or wondered whether global estimators like genetic correlations tell the full story about the relationship between two phenotypes, then check out @michelnivard.bsky.social thread on some work we’ve been doing to model this.
Reposted by Tinca JC Polderman
Did you know Elon Musk was a Fellow of the Royal Society?
Yes, that Elon Musk.
Respect to Profs @deevybee.bsky.social & Andrew Millar who have resigned over his continuing membership. And @scurry.bsky.social who has 1300+ scientists signing his open letter to the Society's President (link below)
Yes, that Elon Musk.
Respect to Profs @deevybee.bsky.social & Andrew Millar who have resigned over his continuing membership. And @scurry.bsky.social who has 1300+ scientists signing his open letter to the Society's President (link below)
Elon Musk remains a Fellow of the Royal Society as he guts US aid and research
The UK's Royal Society was founded in 1660. Among its fellows have been numbered some of the most notable scientists in human history, such as Isaac Newton, Charles Darwin and Albert Einstein. Electio...
campaigncc.gn.apc.org
February 13, 2025 at 4:28 PM
Did you know Elon Musk was a Fellow of the Royal Society?
Yes, that Elon Musk.
Respect to Profs @deevybee.bsky.social & Andrew Millar who have resigned over his continuing membership. And @scurry.bsky.social who has 1300+ scientists signing his open letter to the Society's President (link below)
Yes, that Elon Musk.
Respect to Profs @deevybee.bsky.social & Andrew Millar who have resigned over his continuing membership. And @scurry.bsky.social who has 1300+ scientists signing his open letter to the Society's President (link below)
Reposted by Tinca JC Polderman
PhD students in social sciences studying "metascience" and AI: This looks like an *AMAZING* opportunity. Fully funded research postdoc that can be housed at whatever university you can find an appropriate mentor. sloan.org/programs/dig...
Call for submissions: Metascience and AI postdoctoral fellowship | Alfred P. Sloan Foundation
Our mission is to make the world a better place through the advancement of scientific knowledge.
sloan.org
February 13, 2025 at 5:19 PM
PhD students in social sciences studying "metascience" and AI: This looks like an *AMAZING* opportunity. Fully funded research postdoc that can be housed at whatever university you can find an appropriate mentor. sloan.org/programs/dig...
Reposted by Tinca JC Polderman
Latest blogpost on Musk/Royal Society debacle: deevybee.blogspot.com/2025/02/seve... I look at the reasons that have been given for inaction, and find them wanting. @royalsociety.org
Seven reasons for keeping Elon Musk as a Fellow of the Royal Society
Last November, I wrote a blogpost explaining why I had resigned as a Fellow of the Royal Society (FRS). In brief, over the summer a group ...
deevybee.blogspot.com
February 12, 2025 at 10:50 AM
Latest blogpost on Musk/Royal Society debacle: deevybee.blogspot.com/2025/02/seve... I look at the reasons that have been given for inaction, and find them wanting. @royalsociety.org