Kevin C Klatt, PhD, RD
@kcklatt.bsky.social
Assistant Prof, @uoftnutrisci.bsky.social . #Metabolism Researcher, #Dietitian.
Associate Editor, American Journal of Clinical Nutrition. 🎙️Host, 'AJCN In Press' 🎙️
By way of: UC Berkeley, Baylor CoM, NIH, Cornell
Kcklatt.substack.com
Associate Editor, American Journal of Clinical Nutrition. 🎙️Host, 'AJCN In Press' 🎙️
By way of: UC Berkeley, Baylor CoM, NIH, Cornell
Kcklatt.substack.com
Pinned
This year's Annual Review of Nutrition is out and full of really great reads.
My contribution details the broad history of nutritional guidance in America & covers the forces (science/politics/culture) that have driven the evolution of nutrition guidance.
www.annualreviews.org/content/jour...
My contribution details the broad history of nutritional guidance in America & covers the forces (science/politics/culture) that have driven the evolution of nutrition guidance.
www.annualreviews.org/content/jour...
Supervisors in 2026 are very micromanagey.
January 5, 2026 at 7:25 PM
Supervisors in 2026 are very micromanagey.
Exploring the world of science youtube - anybody have recs?
General, mol/cell bio, nutrition/metabolism, medicine, epidemiology, basics through statistical methods, etc appreciated!
General, mol/cell bio, nutrition/metabolism, medicine, epidemiology, basics through statistical methods, etc appreciated!
January 2, 2026 at 5:48 PM
Exploring the world of science youtube - anybody have recs?
General, mol/cell bio, nutrition/metabolism, medicine, epidemiology, basics through statistical methods, etc appreciated!
General, mol/cell bio, nutrition/metabolism, medicine, epidemiology, basics through statistical methods, etc appreciated!
Reposted by Kevin C Klatt, PhD, RD
2026 will bring waves of innovation to GLP-1 medicines from mechanisms to modalities to molecules delivery systems and new indications. #weightloss #obesity A glimpse of the.future here www.nature.com/articles/s41...
The expanding landscape of GLP-1 medicines - Nature Medicine
This Review discusses the expansion of glucagon-like peptide-1 (GLP-1) medicines beyond type 2 diabetes and obesity, outlining opportunities for new indications, key questions around benefits and long...
www.nature.com
January 2, 2026 at 10:12 AM
2026 will bring waves of innovation to GLP-1 medicines from mechanisms to modalities to molecules delivery systems and new indications. #weightloss #obesity A glimpse of the.future here www.nature.com/articles/s41...
Reposted by Kevin C Klatt, PhD, RD
American food safety could be headed for a breakdown www.statnews.com/2025/12/22/a...
American food safety could be headed for a breakdown
More Americans will be exposed to foodborne illness as a result of this year's funding cuts, food safety experts predict
www.statnews.com
December 22, 2025 at 12:01 PM
American food safety could be headed for a breakdown www.statnews.com/2025/12/22/a...
Reposted by Kevin C Klatt, PhD, RD
New article in The Lancet on the NIH situation over the past year and into the future.
www.thelancet.com/action/showP...
1/3
www.thelancet.com/action/showP...
1/3
Grants under threat at the US National Institutes of Health
Changes to how research grants are assessed and awarded are undermining the world's
largest public funder of biomedical research. Washington Correspondent Susan Jaffe
reports.
www.thelancet.com
December 20, 2025 at 5:03 PM
New article in The Lancet on the NIH situation over the past year and into the future.
www.thelancet.com/action/showP...
1/3
www.thelancet.com/action/showP...
1/3
Reposted by Kevin C Klatt, PhD, RD
⚡️Mitochondria make ATP, the energy that powers life. But in neurons, with axons up to a meter long, how do these tiny power plants stay functional in the right places? We went looking. 1/n www.biorxiv.org/content/10.6...
Self-renewal of neuronal mitochondria through asymmetric division
Mitochondrial ATP production is essential for life. Mitochondrial function depends on the spatio-temporal coordination of nuclear and mitochondrial genome expression, yet how this coordination occurs ...
www.biorxiv.org
December 18, 2025 at 8:36 PM
⚡️Mitochondria make ATP, the energy that powers life. But in neurons, with axons up to a meter long, how do these tiny power plants stay functional in the right places? We went looking. 1/n www.biorxiv.org/content/10.6...
Reposted by Kevin C Klatt, PhD, RD
Pleased to annouce the publication of our new collaboration with Spencer Haws and @johndenu.bsky.social "Depletion of individual dietary amino acids induce distinct metabolic and chromatin states"
December 18, 2025 at 9:02 PM
Pleased to annouce the publication of our new collaboration with Spencer Haws and @johndenu.bsky.social "Depletion of individual dietary amino acids induce distinct metabolic and chromatin states"
Wildly unethical and grotesque to damn African children to lifelong chronic liver disease so some pseudo-'evidence based' medicine advocates can push fairy tales about a lack of placebo controlled trials.
Another sad chapter to come in Medical Apartheid.
Another sad chapter to come in Medical Apartheid.
On the same day he stripped AAP of millions in grant funding in retaliation, RFK Jr awarded $1.6M to Tracy Høeg's Danish friends for a grossly unethical study that will expose African babies to hep B for no reason than it's politically expedient.
Steal from American taxpayers, give to MAHA cronies.
Steal from American taxpayers, give to MAHA cronies.
CDC awards $1.6 million for new hepatitis B vaccine study in Guinea-Bissau. Although the award recipients aren't named, the grant seems tailored to Danish researchers whose work is championed by anti-vaxxers but challenged by mainstream scientists.
www.cidrap.umn.edu/childhood-va...
www.cidrap.umn.edu/childhood-va...
December 18, 2025 at 4:42 PM
Wildly unethical and grotesque to damn African children to lifelong chronic liver disease so some pseudo-'evidence based' medicine advocates can push fairy tales about a lack of placebo controlled trials.
Another sad chapter to come in Medical Apartheid.
Another sad chapter to come in Medical Apartheid.
Reposted by Kevin C Klatt, PhD, RD
On the same day he stripped AAP of millions in grant funding in retaliation, RFK Jr awarded $1.6M to Tracy Høeg's Danish friends for a grossly unethical study that will expose African babies to hep B for no reason than it's politically expedient.
Steal from American taxpayers, give to MAHA cronies.
Steal from American taxpayers, give to MAHA cronies.
CDC awards $1.6 million for new hepatitis B vaccine study in Guinea-Bissau. Although the award recipients aren't named, the grant seems tailored to Danish researchers whose work is championed by anti-vaxxers but challenged by mainstream scientists.
www.cidrap.umn.edu/childhood-va...
www.cidrap.umn.edu/childhood-va...
CDC awards $1.6 million for hepatitis B vaccine study, likely to controversial Danish researchers
www.cidrap.umn.edu
December 18, 2025 at 4:31 PM
On the same day he stripped AAP of millions in grant funding in retaliation, RFK Jr awarded $1.6M to Tracy Høeg's Danish friends for a grossly unethical study that will expose African babies to hep B for no reason than it's politically expedient.
Steal from American taxpayers, give to MAHA cronies.
Steal from American taxpayers, give to MAHA cronies.
Had fun working w colleagues on this updated Systematic Review & Meta Analysis of trials reducing or modifying saturated fat published in @annalsofim.bsky.social -this work has been ongoing for a couple years but the timing of it wrapping up ¤t political landscape couldnt be more serendipitous
December 16, 2025 at 11:41 PM
Had fun working w colleagues on this updated Systematic Review & Meta Analysis of trials reducing or modifying saturated fat published in @annalsofim.bsky.social -this work has been ongoing for a couple years but the timing of it wrapping up ¤t political landscape couldnt be more serendipitous
Sad to see these revised standards for 'integrative and functional nutrition' coming from RDs in the era of MAHA - a time to critically evaluate, not endorse, this psuedoscientific gish gallop of unvalidated diagnostic tests & handwavey rationale for therapy (mitochondria! toxins! epigenetics!)
December 15, 2025 at 6:16 PM
Sad to see these revised standards for 'integrative and functional nutrition' coming from RDs in the era of MAHA - a time to critically evaluate, not endorse, this psuedoscientific gish gallop of unvalidated diagnostic tests & handwavey rationale for therapy (mitochondria! toxins! epigenetics!)
Looking forward to chatting with the British Dietetic Association CVD specialist group about lessons we can learn from MAHA today!
December 11, 2025 at 1:07 PM
Looking forward to chatting with the British Dietetic Association CVD specialist group about lessons we can learn from MAHA today!
Gave some quotes to the @nytimes.com in this piece covering saturated fat in some anticipation of potential rollbacks on these regulations from the Kennedy HHS/Rollins USDA Dietary Guidelines. It's a meaty topic but Dr Callahan covered it well for the general public!
Is saturated fat good for you? Health experts have long recommended limiting it, but Robert F. Kennedy Jr. has signaled a shift in that advice. Here's what to know.
Is Saturated Fat Actually Good for You?
Health experts have long recommended limiting it, but Robert F. Kennedy Jr. has signaled a shift in that advice.
nyti.ms
December 10, 2025 at 2:37 AM
Gave some quotes to the @nytimes.com in this piece covering saturated fat in some anticipation of potential rollbacks on these regulations from the Kennedy HHS/Rollins USDA Dietary Guidelines. It's a meaty topic but Dr Callahan covered it well for the general public!
Very worried we are in for more of these cases, as trust in health institutions continues to plummet and we see the general discourse in nutrition devolve in the most extreme version of good/bad thinking that we've ever seen.
A 5-month-old baby died, & 3 surviving children, ages 2, 4, & 5, had to be hospitalized with rickets, osteopenia, vitamin D deficiency, & significant developmental delays bc their parents put them on “alkaline diets.”
Anyone saying alkalization has health benefits is a murderous liar & a charlatan.
Anyone saying alkalization has health benefits is a murderous liar & a charlatan.
December 9, 2025 at 3:23 AM
Very worried we are in for more of these cases, as trust in health institutions continues to plummet and we see the general discourse in nutrition devolve in the most extreme version of good/bad thinking that we've ever seen.
Reposted by Kevin C Klatt, PhD, RD
#medsky #pedsky #idsky #immunosky #episky
I collaborated with exceptionally talented people in infectious diseases to write this Special Article about aluminum salts in childhood vaccines.
We review the evidence base for key safety concerns and offer guidance for communication with caregivers.
I collaborated with exceptionally talented people in infectious diseases to write this Special Article about aluminum salts in childhood vaccines.
We review the evidence base for key safety concerns and offer guidance for communication with caregivers.
The Role and Safety of Aluminum Adjuvants in Childhood Vaccines
Aluminum salts have been used as adjuvants in vaccines for nearly a century, enhancing the immune response to purified antigens and ensuring durable protection against serious infectious diseases. Des...
publications.aap.org
December 3, 2025 at 3:03 PM
#medsky #pedsky #idsky #immunosky #episky
I collaborated with exceptionally talented people in infectious diseases to write this Special Article about aluminum salts in childhood vaccines.
We review the evidence base for key safety concerns and offer guidance for communication with caregivers.
I collaborated with exceptionally talented people in infectious diseases to write this Special Article about aluminum salts in childhood vaccines.
We review the evidence base for key safety concerns and offer guidance for communication with caregivers.
Trying to update a section of the textbook on mechanisms of 1,25(OH2)D transcriptional repression. The old mechanism of protein-protein interactions at the site of negative VitD response elements is now suspect, due to data duplications/image manipulation, and subsequent retractions.
November 26, 2025 at 1:49 AM
Trying to update a section of the textbook on mechanisms of 1,25(OH2)D transcriptional repression. The old mechanism of protein-protein interactions at the site of negative VitD response elements is now suspect, due to data duplications/image manipulation, and subsequent retractions.
This tweet was in part inspired by posting my OP in my IG stories and getting someone with an affiliate code for a protein powder in their bio telling me it's absurd for a dietitian to be 'promoting' UPFs 😂
This, from @kcklatt.bsky.social on x, is exactly right.
November 22, 2025 at 3:41 PM
This tweet was in part inspired by posting my OP in my IG stories and getting someone with an affiliate code for a protein powder in their bio telling me it's absurd for a dietitian to be 'promoting' UPFs 😂
Reposted by Kevin C Klatt, PhD, RD
This, from @kcklatt.bsky.social on x, is exactly right.
November 22, 2025 at 3:33 PM
This, from @kcklatt.bsky.social on x, is exactly right.
Honestly, it's wild to watch the nutrition community continue to get behind a term like UPF (defined by looking at a ingredients and giving a 'bad' label by the presence of an 'industrial' additive) while this exact, scientifically hollow tactic is being rolled out to scare folks away from vaccines.
Ultra-processed foods – what’s the impact?
In a new Lancet Series, experts warn a global rise in #UPFs presents a growing public health threat.
Read the evidence & policy recommendations ⬇️
spkl.io/63327AduhR
In a new Lancet Series, experts warn a global rise in #UPFs presents a growing public health threat.
Read the evidence & policy recommendations ⬇️
spkl.io/63327AduhR
November 22, 2025 at 3:38 PM
Honestly, it's wild to watch the nutrition community continue to get behind a term like UPF (defined by looking at a ingredients and giving a 'bad' label by the presence of an 'industrial' additive) while this exact, scientifically hollow tactic is being rolled out to scare folks away from vaccines.
This week we've gotten the first test for whether MAHA will push past an anti-establishment politick and get on board with putting their political weight behind some actual legislation with the reintroduction of the Medical Nutrition Therapy Act of 2025.
November 21, 2025 at 9:41 PM
This week we've gotten the first test for whether MAHA will push past an anti-establishment politick and get on board with putting their political weight behind some actual legislation with the reintroduction of the Medical Nutrition Therapy Act of 2025.
Another day, another ad for a new VC backed telehealth company cosplaying as one stop shop comprehensive provider selling wt loss injections/pills, hormones, supplements. They can't possibly provide evidence-based comprehensive care and make the return on investment VCs expect. Where is @FDA @FTC ?
November 18, 2025 at 12:16 AM
Another day, another ad for a new VC backed telehealth company cosplaying as one stop shop comprehensive provider selling wt loss injections/pills, hormones, supplements. They can't possibly provide evidence-based comprehensive care and make the return on investment VCs expect. Where is @FDA @FTC ?
Reposted by Kevin C Klatt, PhD, RD
Wow
'MHRA-led study reveals major inconsistencies in global microbiome research'
www.gov.uk/government/n...
'Species identification varied from 63% to 100% accuracy across different methods, meaning that some laboratories failed to detect a third of the bacterial species present in the sample'
'MHRA-led study reveals major inconsistencies in global microbiome research'
www.gov.uk/government/n...
'Species identification varied from 63% to 100% accuracy across different methods, meaning that some laboratories failed to detect a third of the bacterial species present in the sample'
MHRA-led study reveals major inconsistencies in global microbiome research
International collaboration establishes new quality standards to improve reliability of gut health studies – improving accuracy to provide better diagnosis and treatment.
www.gov.uk
November 16, 2025 at 12:51 PM
Wow
'MHRA-led study reveals major inconsistencies in global microbiome research'
www.gov.uk/government/n...
'Species identification varied from 63% to 100% accuracy across different methods, meaning that some laboratories failed to detect a third of the bacterial species present in the sample'
'MHRA-led study reveals major inconsistencies in global microbiome research'
www.gov.uk/government/n...
'Species identification varied from 63% to 100% accuracy across different methods, meaning that some laboratories failed to detect a third of the bacterial species present in the sample'
It's so grating to continue to watch COVID contrarians put forth the need to improve metabolic health. There's no serious efforts to use policy to improve dietary patterns, coverage of dietitian & exercise physio services; no attempt to regulate food systems so the default choice = healthier choice
Oh look, it’s NIH Director Jay Bhattacharya and sidecar passenger Matthew Memoli blaming individuals for dying during the pandemic, because in their view, they were lazy and ate shitty foods.
There’s a lot more to hate in this article, but that’s the (anti)appetizer.
There’s a lot more to hate in this article, but that’s the (anti)appetizer.
NIH Directors: The World Needs a New Pandemic Playbook
The old one failed to cope with Covid and may even have caused it.
www.city-journal.org
November 16, 2025 at 12:49 AM
It's so grating to continue to watch COVID contrarians put forth the need to improve metabolic health. There's no serious efforts to use policy to improve dietary patterns, coverage of dietitian & exercise physio services; no attempt to regulate food systems so the default choice = healthier choice
New CDC update on infant botulism - 2 new cases since Nov 8th, reported presence of bacteria in an open canister of ByHeart formula from California, and a re all of ByHeart Whole Nutrition Infant Formula for all lots.
share.google/FoBGPHIxF7Q5...
share.google/FoBGPHIxF7Q5...
Investigation Update: Infant Botulism Outbreak, November 2025
Investigation details for an outbreak of infant botulism linked to infant formula, November 2025.
share.google
November 12, 2025 at 12:46 AM
New CDC update on infant botulism - 2 new cases since Nov 8th, reported presence of bacteria in an open canister of ByHeart formula from California, and a re all of ByHeart Whole Nutrition Infant Formula for all lots.
share.google/FoBGPHIxF7Q5...
share.google/FoBGPHIxF7Q5...
Glad to see more test-to-treat dosing trials happening for nutrients. Single dose vs placebo paradigms with no consideration of baseline and achieved levels have resulted in largely null but nearly uninterpretable results.
newsroom.heart.org/news/heart-a...
newsroom.heart.org/news/heart-a...
Heart attack risk halved in adults with heart disease taking tailored vitamin D doses
Research Highlights: Adults with heart disease prescribed vitamin D in doses tailored to reach blood levels considered optimal for heart health (>40-80 ng/mL) had a reduced risk of heart attack by mor...
newsroom.heart.org
November 11, 2025 at 6:35 PM
Glad to see more test-to-treat dosing trials happening for nutrients. Single dose vs placebo paradigms with no consideration of baseline and achieved levels have resulted in largely null but nearly uninterpretable results.
newsroom.heart.org/news/heart-a...
newsroom.heart.org/news/heart-a...