Wonuola Akingbuwa
wonuola.bsky.social
Wonuola Akingbuwa
@wonuola.bsky.social
Assistant professor at VU Amsterdam
Psychiatric genetics
Pinned
Have you ever wondered about nonlinearity in bivariate genetic associations? Or wondered whether global estimators like genetic correlations tell the full story about the relationship between two phenotypes, then check out @michelnivard.bsky.social thread on some work we’ve been doing to model this.
🚨NEW PAPER! Together with Wuno Akingbuwa (@wonuola.bsky.social) we developed a way to estimate non-linear genetic correlations. It didnt sit well with us that known non-linear relations (e.g. BMI and MDD with a famous U shaped ) are poorly captured in statistical genetics. 🧵
www.biorxiv.org
Reposted by Wonuola Akingbuwa
Extremely excited to share the first effort of the Revived Genomics of Personality Consortium: A highly-powered, comprehensive GWAS of the Big Five personality traits in 1.14 million participants from 46 cohorts. www.biorxiv.org/content/10.1...
May 20, 2025 at 10:14 AM
Have you ever wondered about nonlinearity in bivariate genetic associations? Or wondered whether global estimators like genetic correlations tell the full story about the relationship between two phenotypes, then check out @michelnivard.bsky.social thread on some work we’ve been doing to model this.
🚨NEW PAPER! Together with Wuno Akingbuwa (@wonuola.bsky.social) we developed a way to estimate non-linear genetic correlations. It didnt sit well with us that known non-linear relations (e.g. BMI and MDD with a famous U shaped ) are poorly captured in statistical genetics. 🧵
www.biorxiv.org
February 17, 2025 at 12:18 PM
Reposted by Wonuola Akingbuwa
🚨NEW PAPER! Together with Wuno Akingbuwa (@wonuola.bsky.social) we developed a way to estimate non-linear genetic correlations. It didnt sit well with us that known non-linear relations (e.g. BMI and MDD with a famous U shaped ) are poorly captured in statistical genetics. 🧵
www.biorxiv.org
February 14, 2025 at 1:30 PM
Reposted by Wonuola Akingbuwa
Outreach in psychiatric genetics - What is it? Why do we need it? How can we do it well?

Join me, Niamh Ryan, and Cindy Bulik this Friday (6th) at 10am EST / 4pm CET / 3pm UTC where we'll discuss all of this for the PGC (@pgcgenetics.bsky.social) World Wide Lab 🌎

🔗 us02web.zoom.us/j/88690327502
December 4, 2024 at 10:24 AM