The Menachery Lab
@themenacherylab.bsky.social
A coronavirus lab looking for low hanging pebbles and shiny fruit.
Emory University
Emory University
A nice honor to be named to Clarivate’s Highly Cited Researchers for 2025.
The recognition is a testament to all the hard work my research group and our collaborators have done over the years.
news.emory.edu/stories/2025...
The recognition is a testament to all the hard work my research group and our collaborators have done over the years.
news.emory.edu/stories/2025...
Nine Emory faculty recognized among world’s most influential researchers in 2025 | Emory University | Atlanta GA
Nine Emory faculty members are among the list of the world's most influential and highly cited researchers for 2025, as compiled by the data analytics firm Clarivate.
news.emory.edu
November 13, 2025 at 8:16 PM
A nice honor to be named to Clarivate’s Highly Cited Researchers for 2025.
The recognition is a testament to all the hard work my research group and our collaborators have done over the years.
news.emory.edu/stories/2025...
The recognition is a testament to all the hard work my research group and our collaborators have done over the years.
news.emory.edu/stories/2025...
Reposted by The Menachery Lab
New #coronavirus #postacute lung pathogenesis paper from my friend Dr. John Powers is up at @asm.org JVI. journals.asm.org/doi/10.1128/... Confusing as to why this link shows a rotund blue bird. #PASC #SARSCoV2 #Omicron #LoveVirology #JVI #ASM #virology
Mouse-adapted SARS-CoV-2 Omicron BA.5 infection induces post-acute lung fibrosis in BALB/c mice | Journal of Virology
To best combat the evolving landscape of SARS-CoV-2 variants of interest and variants
of concern, the development of effective small animal models is of critical importance.
Herein, we describe the de...
journals.asm.org
November 6, 2025 at 2:37 PM
New #coronavirus #postacute lung pathogenesis paper from my friend Dr. John Powers is up at @asm.org JVI. journals.asm.org/doi/10.1128/... Confusing as to why this link shows a rotund blue bird. #PASC #SARSCoV2 #Omicron #LoveVirology #JVI #ASM #virology
Reposted by The Menachery Lab
NIH will spend its full $48B budget — but multi-year funding means fewer projects, record-low grant success, and a warning for U.S. science.👉 lfdn.org/3KOs2hT
💜Learn how you can support NIH funding: www.lustgarten.org/forging-ahead
#ResearchMatters
💜Learn how you can support NIH funding: www.lustgarten.org/forging-ahead
#ResearchMatters
October 1, 2025 at 8:07 PM
NIH will spend its full $48B budget — but multi-year funding means fewer projects, record-low grant success, and a warning for U.S. science.👉 lfdn.org/3KOs2hT
💜Learn how you can support NIH funding: www.lustgarten.org/forging-ahead
#ResearchMatters
💜Learn how you can support NIH funding: www.lustgarten.org/forging-ahead
#ResearchMatters
Feels like everything has moved slow since restarting here at Emory last year, but glad to have been nominated by my new peers and selected for this recognition.
med.emory.edu/about/facult...
med.emory.edu/about/facult...
September 12, 2025 at 2:53 PM
Feels like everything has moved slow since restarting here at Emory last year, but glad to have been nominated by my new peers and selected for this recognition.
med.emory.edu/about/facult...
med.emory.edu/about/facult...
I wish my all my students labeled their figures as well as my daughter.
September 9, 2025 at 12:36 AM
I wish my all my students labeled their figures as well as my daughter.
Reposted by The Menachery Lab
there is no question in my mind that rfk jr is the most dangerous person in this administration and that his eugenicist ideology threatens the lives of millions of people www.advocate.com/politics/dem...
RFK Jr.’s damage to the CDC is ‘past the point of no return,’ Dr. Demetre Daskalakis warns
“The CDC you knew is over,” the infectious diseases doctor told The Advocate. “Unless someone takes radical action, there is nothing there that can be salvaged.”
www.advocate.com
August 29, 2025 at 8:53 PM
there is no question in my mind that rfk jr is the most dangerous person in this administration and that his eugenicist ideology threatens the lives of millions of people www.advocate.com/politics/dem...
Reposted by The Menachery Lab
What the CDC lost: a closer look at the top-ranking officials who have quit
HHS Secretary RFK Jr. says agency suffers from ‘malaise,’ but departed officials had deep expertise
Knowledge, experience and talent lost due to political ideology.
HHS Secretary RFK Jr. says agency suffers from ‘malaise,’ but departed officials had deep expertise
Knowledge, experience and talent lost due to political ideology.
What the CDC lost: a closer look at the top-ranking officials who have quit
Here is a closer look at the top-ranking officials who resigned from the CDC this week.
www.statnews.com
August 28, 2025 at 7:08 PM
What the CDC lost: a closer look at the top-ranking officials who have quit
HHS Secretary RFK Jr. says agency suffers from ‘malaise,’ but departed officials had deep expertise
Knowledge, experience and talent lost due to political ideology.
HHS Secretary RFK Jr. says agency suffers from ‘malaise,’ but departed officials had deep expertise
Knowledge, experience and talent lost due to political ideology.
Reposted by The Menachery Lab
Enough is enough. The health of the country is in danger. Read our resignation letters: insidemedicine.substack.com/p/breaking-n...
Breaking News: Read three top CDC officials' resignation emails.
The end of an era.
insidemedicine.substack.com
August 28, 2025 at 3:38 AM
Enough is enough. The health of the country is in danger. Read our resignation letters: insidemedicine.substack.com/p/breaking-n...
Reposted by The Menachery Lab
Reposted by The Menachery Lab
#WomenInSTEM becoming independent: People should feel free to be themselves and do great science. We asked ten women researchers about their science and the process of setting up a lab as an independent researcher: rupress.org/jem/article/...
August 15, 2025 at 2:45 PM
#WomenInSTEM becoming independent: People should feel free to be themselves and do great science. We asked ten women researchers about their science and the process of setting up a lab as an independent researcher: rupress.org/jem/article/...
Spent the weekend here reflecting & reconnecting. A sorrowful few days thinking of what was lost.
The CDC is ubiquitous to our community. An attack on us all.
Officer David Rose died protecting us. Take a moment to support & share efforts for the family he left.
www.gofundme.com/f/7xahr9-off...
The CDC is ubiquitous to our community. An attack on us all.
Officer David Rose died protecting us. Take a moment to support & share efforts for the family he left.
www.gofundme.com/f/7xahr9-off...
Donate to Officer Rose's Official GoFundMe, organized by Mrs Rose
Officer David Rose was more than a dedicated public servant - He was a loving father, a dev… Mrs Rose needs your support for Officer Rose's Official GoFundMe
www.gofundme.com
August 11, 2025 at 12:15 PM
Spent the weekend here reflecting & reconnecting. A sorrowful few days thinking of what was lost.
The CDC is ubiquitous to our community. An attack on us all.
Officer David Rose died protecting us. Take a moment to support & share efforts for the family he left.
www.gofundme.com/f/7xahr9-off...
The CDC is ubiquitous to our community. An attack on us all.
Officer David Rose died protecting us. Take a moment to support & share efforts for the family he left.
www.gofundme.com/f/7xahr9-off...
Lab members in ATL are all accounted and safe.
August 8, 2025 at 9:56 PM
Lab members in ATL are all accounted and safe.
#ASV2025 is where you run into a Nobel Laureate at the bar late at night and they wish you a happy birthday.
My birthday is in March. But thanks.
Happy birthday @lakdawalalab.bsky.social
My birthday is in March. But thanks.
Happy birthday @lakdawalalab.bsky.social
July 16, 2025 at 2:03 PM
#ASV2025 is where you run into a Nobel Laureate at the bar late at night and they wish you a happy birthday.
My birthday is in March. But thanks.
Happy birthday @lakdawalalab.bsky.social
My birthday is in March. But thanks.
Happy birthday @lakdawalalab.bsky.social
Reposted by The Menachery Lab
🚨Second study from the lab. @CellReports
SARS-CoV- and SARS-CoV-2-like viruses are found in insectivorous bats, but the antiviral responses in these bats remain less studied. Here we show how bat cells respond to SARS-CoV-2 and shed light on virus entry.
www.cell.com/cell-reports... #LZCI
SARS-CoV- and SARS-CoV-2-like viruses are found in insectivorous bats, but the antiviral responses in these bats remain less studied. Here we show how bat cells respond to SARS-CoV-2 and shed light on virus entry.
www.cell.com/cell-reports... #LZCI
Early innate immune response and evolution of a SARS-CoV-2 furin cleavage site inactive variant in bat cells
Baid et al. show that insectivorous E. fuscus bat cells have evolved an advantageous
early innate immune response to SARS-CoV-2 infection relative to human cells. Additionally,
they extend molecular e...
www.cell.com
July 2, 2025 at 4:06 AM
🚨Second study from the lab. @CellReports
SARS-CoV- and SARS-CoV-2-like viruses are found in insectivorous bats, but the antiviral responses in these bats remain less studied. Here we show how bat cells respond to SARS-CoV-2 and shed light on virus entry.
www.cell.com/cell-reports... #LZCI
SARS-CoV- and SARS-CoV-2-like viruses are found in insectivorous bats, but the antiviral responses in these bats remain less studied. Here we show how bat cells respond to SARS-CoV-2 and shed light on virus entry.
www.cell.com/cell-reports... #LZCI
Reposted by The Menachery Lab
A short thread about the people in my lab who will present posters and give rapid talks at #ASMmicrobe: 🧵
June 19, 2025 at 11:53 PM
A short thread about the people in my lab who will present posters and give rapid talks at #ASMmicrobe: 🧵
Reposted by The Menachery Lab
Excited for the recipient of the @ASM Elizabeth O. King Lecturer Award at this year’s #ASMMicrobe.
June 20, 2025 at 12:39 AM
Excited for the recipient of the @ASM Elizabeth O. King Lecturer Award at this year’s #ASMMicrobe.
2 in a row in the Journal of Virology.
A new paper from our group & the new Johnson lab at UTMB.
Here, we find multiple variant mutations in the SR rich domain of N facilitate improved infection with #SARS2.
A brief thread since this didn't get preprinted
journals.asm.org/doi/10.1128/...
A new paper from our group & the new Johnson lab at UTMB.
Here, we find multiple variant mutations in the SR rich domain of N facilitate improved infection with #SARS2.
A brief thread since this didn't get preprinted
journals.asm.org/doi/10.1128/...
Convergent evolution in nucleocapsid facilitated SARS-CoV-2 adaptation for human infection | Journal of Virology
After its emergence, SARS-CoV-2 rapidly adapted to human infection, acquiring numerous
mutations across its genome. Many of these mutations remain uncharacterized. This
study examines a mutational hot...
journals.asm.org
June 13, 2025 at 2:18 PM
2 in a row in the Journal of Virology.
A new paper from our group & the new Johnson lab at UTMB.
Here, we find multiple variant mutations in the SR rich domain of N facilitate improved infection with #SARS2.
A brief thread since this didn't get preprinted
journals.asm.org/doi/10.1128/...
A new paper from our group & the new Johnson lab at UTMB.
Here, we find multiple variant mutations in the SR rich domain of N facilitate improved infection with #SARS2.
A brief thread since this didn't get preprinted
journals.asm.org/doi/10.1128/...
Our new paper on SARS-CoV-2 furin cleavage site is now out at JVI.
Study examines disruption (rather than deletion) of the FCS & maintains the longer S1/S2 loop found in #SARS2.
FCS disruption attenuates pathogenesis, but not required (but helps) transmission.
journals.asm.org/doi/10.1128/...
Study examines disruption (rather than deletion) of the FCS & maintains the longer S1/S2 loop found in #SARS2.
FCS disruption attenuates pathogenesis, but not required (but helps) transmission.
journals.asm.org/doi/10.1128/...
The furin cleavage site is required for pathogenesis, but not transmission, of SARS-CoV-2 | Journal of Virology
The presence of the furin cleavage site (FCS) within the spike protein of SARS-CoV-2 distinguishes it from other sarbecoviruses found in nature. While prior works have deleted the FCS, these mutant viruses also shortened the S1/S2 loop, which is known to ...
journals.asm.org
June 12, 2025 at 2:12 PM
Our new paper on SARS-CoV-2 furin cleavage site is now out at JVI.
Study examines disruption (rather than deletion) of the FCS & maintains the longer S1/S2 loop found in #SARS2.
FCS disruption attenuates pathogenesis, but not required (but helps) transmission.
journals.asm.org/doi/10.1128/...
Study examines disruption (rather than deletion) of the FCS & maintains the longer S1/S2 loop found in #SARS2.
FCS disruption attenuates pathogenesis, but not required (but helps) transmission.
journals.asm.org/doi/10.1128/...
Reposted by The Menachery Lab
Non-spike protein mutations in #SARSCoV2, likely to impact viral properties, are understudied. @brucelab.bsky.social show that a #nucleocapsid protein mutation in Delta variant enhances viral growth in vitro & in vivo by increasing viral genome #encapsidation @plosbiology.org 🧪 plos.io/4iBYsaI
April 30, 2025 at 1:01 PM
Non-spike protein mutations in #SARSCoV2, likely to impact viral properties, are understudied. @brucelab.bsky.social show that a #nucleocapsid protein mutation in Delta variant enhances viral growth in vitro & in vivo by increasing viral genome #encapsidation @plosbiology.org 🧪 plos.io/4iBYsaI
Reposted by The Menachery Lab
I have exhorted others to share positive news even in these uncertain times for US science.
I am really excited that @tamanash.bsky.social’s first paper on the remarkable evolutionary gymnastics of dual-host viruses (even in single codons) is now online.
Follow along here 🧪🧵
I am really excited that @tamanash.bsky.social’s first paper on the remarkable evolutionary gymnastics of dual-host viruses (even in single codons) is now online.
Follow along here 🧪🧵
Our study exploring the evolutionary mechanism of alphavirus opal codon retention is now online! www.science.org/doi/10.1126/...
A conserved opal termination codon optimizes a temperature-dependent trade-off between protein production and processing in alphaviruses
Alphaviruses optimize viral polymerase production and polyprotein processing at distinct temperatures via a premature stop codon.
www.science.org
April 18, 2025 at 11:11 PM
I have exhorted others to share positive news even in these uncertain times for US science.
I am really excited that @tamanash.bsky.social’s first paper on the remarkable evolutionary gymnastics of dual-host viruses (even in single codons) is now online.
Follow along here 🧪🧵
I am really excited that @tamanash.bsky.social’s first paper on the remarkable evolutionary gymnastics of dual-host viruses (even in single codons) is now online.
Follow along here 🧪🧵
Absolutely. The work by @tamanash.bsky.social is a tour de force and an example of clever, beautiful science towards better understanding of alphavirus biology.
Based on what I heard, an example of a great post-doc & future star in virology. Read his preprint:
pubmed.ncbi.nlm.nih.gov/39229031/
Based on what I heard, an example of a great post-doc & future star in virology. Read his preprint:
pubmed.ncbi.nlm.nih.gov/39229031/
April 1, 2025 at 12:43 PM
Absolutely. The work by @tamanash.bsky.social is a tour de force and an example of clever, beautiful science towards better understanding of alphavirus biology.
Based on what I heard, an example of a great post-doc & future star in virology. Read his preprint:
pubmed.ncbi.nlm.nih.gov/39229031/
Based on what I heard, an example of a great post-doc & future star in virology. Read his preprint:
pubmed.ncbi.nlm.nih.gov/39229031/
Really interesting talk from @harmitmalik.bsky.social on alpha virus evolution and the opal codon.
A little rusty and just barely got #bingo. Need to get back to it.
A little rusty and just barely got #bingo. Need to get back to it.
March 31, 2025 at 8:50 PM
Really interesting talk from @harmitmalik.bsky.social on alpha virus evolution and the opal codon.
A little rusty and just barely got #bingo. Need to get back to it.
A little rusty and just barely got #bingo. Need to get back to it.
It these trying time, we need to lean on what we do best.
For me, that means #bingo for MMG seminar with @harmitmalik.bsky.social
A good speaker to start this back up at Emory.
For me, that means #bingo for MMG seminar with @harmitmalik.bsky.social
A good speaker to start this back up at Emory.
March 31, 2025 at 7:50 PM
It these trying time, we need to lean on what we do best.
For me, that means #bingo for MMG seminar with @harmitmalik.bsky.social
A good speaker to start this back up at Emory.
For me, that means #bingo for MMG seminar with @harmitmalik.bsky.social
A good speaker to start this back up at Emory.