Tamara Basta
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tamarabasta.bsky.social
Tamara Basta
@tamarabasta.bsky.social
96 followers 100 following 6 posts
Assistant professor at Paris-Saclay University & at Institute for integrative biology of the cell (I2BC). Interested in Archaea, hyperthermophiles, DNA topology, topoisomerases.
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Reposted by Tamara Basta
lsiexeter.bsky.social
Last chance to apply for one of the LSI PhD projects intake Sept 2026! Deadline tomorrow, 26.11.2025, noon. www.exeter.ac.uk/research/ins... @exeter.ac.uk @lsiexeter.bsky.social
November 25, 2025 at 5:07 PM
Reposted by Tamara Basta
danielabarilla.bsky.social
📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social

www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
Archaeal cells whose DNA has been stained with a blue dye. Zoomed-in images of mutant cells that display chromosome segregation defects. High-resolution images of DNA-protein complexes obtained with atomic force microscopy. Upon binding, the protein bridges distant sites, forming loops.
November 9, 2025 at 5:20 PM
Reposted by Tamara Basta
pforterrr.bsky.social
A very nice review on my favorite archaea. The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology journals.asm.org/doi/10.1128/...
The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology
The exploration of life in extreme environments gained prominence with Thomas Brock’s “Life at High Temperatures” (1), and his subsequent isolation of Thermus aquaticus with Hudson Freeze in 1969 (2) ...
journals.asm.org
November 6, 2025 at 9:39 AM
Reposted by Tamara Basta
New article online: Modulation of archaeal hypernucleosome structure and stability by Mg2+

In this work, we dissect the effects of Mg2+ on hypernucleosomes formed by the canonical histones from M. fervidus (HMfA and HMfB) and T. kodakarensis (HTkA and HTkB).

www.sciencedirect.com/science/arti...
Modulation of archaeal hypernucleosome structure and stability by Mg2+
DNA-wrapping histone proteins play a central role in chromatin organization, gene expression and regulation in most eukaryotes and archaea. While the …
www.sciencedirect.com
November 6, 2025 at 7:53 AM
Reposted by Tamara Basta
drym.bsky.social
The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology journals.asm.org/doi/10.1128/...
The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology
The exploration of life in extreme environments gained prominence with Thomas Brock’s “Life at High Temperatures” (1), and his subsequent isolation of Thermus aquaticus with Hudson Freeze in 1969 (2) ...
journals.asm.org
November 5, 2025 at 8:06 PM
Reposted by Tamara Basta
tunglejic.bsky.social
tunglejic.bsky.social Tung Le @tunglejic.bsky.social · Oct 3
Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!
johninnescentre.bsky.social John Innes Centre @johninnescentre.bsky.social · Oct 3
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.

Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.

Find out more: www.jic.ac.uk/training-car...
October 21, 2025 at 9:16 PM
Reposted by Tamara Basta
cryoclem.bsky.social
Our work on ribosome hibernation in archaea is out!
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
October 13, 2025 at 4:26 PM
Reposted by Tamara Basta
stcmicrobeblog.bsky.social
ribosomologists take note 👇

archaeal ribosome hibernation factors aRDF, Dri, ...and now: Hib (see ALT)
#Archaea #ArchaeaSky
c. Hib 3D structure. The N-terminal domain of Hib (1-269) is made up of four CBS domains. Two CBS domains interacts through their beta-sheets to form a bateman module. Two bateman modules interact to form a disk-like structure defined as parallel CBS module in51. Each CBS domain consists of three-standed (two parallel and one anti-parallel) b-sheet with two a-helices52. In domains 2,3 and four the first beta strand is less well defined and extended, as already mentionned in other CBS-domain containing structures. One long loop is inserted between a8 and b10 of the third CBS domain. The C-terminal domain (272-387) has the babbba topology found in all bacterial HPF/RaiA-like structures. The five last residues are not visible in the cryo-EM map.
October 12, 2025 at 7:13 PM
Reposted by Tamara Basta
daumlab.bsky.social
Out in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail
This structure of an archaeal tailed virus (arTV) provides detailed insights into arTV assembly and infection mechanisms.
www.science.org
October 6, 2025 at 11:31 AM
Reposted by Tamara Basta
tunglejic.bsky.social
tunglejic.bsky.social Tung Le @tunglejic.bsky.social · Oct 3
Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!
johninnescentre.bsky.social John Innes Centre @johninnescentre.bsky.social · Oct 3
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.

Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.

Find out more: www.jic.ac.uk/training-car...
October 7, 2025 at 6:20 AM
Reposted by Tamara Basta
sfbbm.bsky.social
Du 2 au 5 décembre 2025, Université Paris-Cité
Congrès « Enzymes, Proteolysis & Metabolism at the crossroads of Biochemistry », premier congrès commun de trois Groupes Thématiques de la SFBBM.

gts-sfbbm-2025.sciencesconf.org?lang=fr
Enzymes, Proteolysis & Metabolism at the crossroads of Biochemistry - Sciencesconf.org
Présentation
gts-sfbbm-2025.sciencesconf.org
October 7, 2025 at 8:10 AM
Reposted by Tamara Basta
tobiaswarnecke.bsky.social
Become my colleague @oxfordbiochemistry.bsky.social !
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism

my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
September 29, 2025 at 9:25 AM
Reposted by Tamara Basta
danielabarilla.bsky.social
#BioPhyChrom25 gala dinner at the 14th century #Hospitium venue in York, and @agnesnoy.bsky.social talk. Lots of discussion and ideas for BioPhyChrom2027… Great vibes and atmosphere!
@biophychrom.bsky.social @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social 🧬
September 18, 2025 at 11:14 PM
Reposted by Tamara Basta
biochemsoc.bsky.social
That’s a wrap for The Biology and Physics of Prokaryotic Chromosomes VII 2025. A big thank you to all those who attended 🧪 #BioPhyChrom2025 #BiochemEvents
Group photo
September 19, 2025 at 8:50 AM
Reposted by Tamara Basta
vslioy.bsky.social
#Biophychrom2025 is over, but we spent four exciting days discussing the biology and physics of prokaryotic chromosomes. Congratulations to all the attendees for making this conference a success.
@biochemsoc.bsky.social
@danielabarilla.bsky.social
@graingerlab.bsky.social
@damelab.bsky.social
September 19, 2025 at 5:57 PM
Reposted by Tamara Basta
danielabarilla.bsky.social
With evidence attached 😊
#BioPhyChrom2025
@biochemsoc.bsky.social @biophychrom.bsky.social
@damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @lauraspagnolo.bsky.social @tamarabasta.bsky.social
September 18, 2025 at 6:06 AM
Reposted by Tamara Basta
danielabarilla.bsky.social
The countdown for #BioPhyChrom2025 is nearly over: -2 days to go… What a fête of chromosome biology & physics!🧬

Safe journey everyone! ✈️🚂
@vslioy.bsky.social @damelab.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social

www.eventsforce.net/biochemsoc/f...
Front entrance to York Minster cathedral with a blue sky background.
September 13, 2025 at 10:52 AM
Reposted by Tamara Basta
Tomorrow is the start of Biology and Physics of Prokaryotic Chromosomes VII. Great speakers and participants. Excellent support by the Biochem. Society. @biochemsoc.bsky.social
@danielabarilla.bsky.social @vslioy.bsky.social
@graingerlab.bsky.social
@damelab.bsky.social
#BioPhyChrom2025
September 15, 2025 at 8:29 AM
Reposted by Tamara Basta
danielabarilla.bsky.social
York calling! 📣 🧬🧬🧬

Join us at www.biochemistry.org/events-and-t...

⏳⏰ Early bird deadline approaching soon, 16 July! Do not miss out! Half of the talks selected from abstracts.
@damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social @biophychrom.bsky.social
View of a street in York with old houses on both sides and the towers of York Minster in the background.
July 2, 2025 at 5:22 PM
Reposted by Tamara Basta
lauraeme.bsky.social
Excited to share our new paper in @cellreports.bsky.social that reshapes our understanding of chromosome organization's deep evolutionary roots! Our work dives into the origins of the machinery that structures our very genomes.

🔗: doi.org/10.1016/j.ce...

#Genomics #Evolution #CellBiology #LECA
June 22, 2025 at 12:15 AM
Reposted by Tamara Basta
danielabarilla.bsky.social
Chromosome Enthusiasts, join us at The Biology & Physics of Prokaryotic Chromosomes 🧬! Friendly community, fantastic speakers line-up, grant writing session for ECRs. Early-bird deadline approaching soon.
@damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biophychrom.bsky.social
Flyer advertising The Biology and Physics of Prokaryotic Chromosome conference that will be held in York, 16-19 September 2025.
June 11, 2025 at 10:53 AM
Reposted by Tamara Basta
hiro-imachi.bsky.social
Would you like to work with us?
At JAMSTEC, we are recruiting postdoctoral researchers through the Young Research Fellow program.
This program allows fellows to independently pursue their own research projects.
www.jamstec.go.jp/recruit/e/jy...
JAMSTEC Young Research Fellow (JYRF) | JAMSTEC - JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGY
JAMSTEC Young Research Fellow (JYRF)
www.jamstec.go.jp
June 4, 2025 at 7:38 AM
Reposted by Tamara Basta
curiousdina.bsky.social
Friendly reminder for all people who love their thermophilic microbe friends: early bird registration for the Thermophiles conference in Münster/GER in September is open until June 1st. Don't miss out www.uni-muenster.de/Thermophiles...
Thermophiles 2025
www.uni-muenster.de
May 27, 2025 at 6:03 PM
Reposted by Tamara Basta
danielabarilla.bsky.social
#ArchaeaSky #MicroSky
dodonova-sveta.bsky.social Svetlana Dodonova @dodonova-sveta.bsky.social · May 26
We’ve uncovered Asgard chromatin structures formed by a Hodarchaeal histone : closed hypernucleosome conserved in archaea and an open form resembling the H3-H4 eukaryotic octasome. Fantastic work by @harshranawat.bsky.social!
www.biorxiv.org/content/10.1...
#Chromatin #Asgard #Archaea #cryoEM
May 26, 2025 at 6:14 PM
Reposted by Tamara Basta
dodonova-sveta.bsky.social
And big thanks of course to all involved: the Quail lab @embl.org, and the @damelab.bsky.social
May 26, 2025 at 7:10 PM