Tamara Basta
@tamarabasta.bsky.social
Assistant professor at Paris-Saclay University & at Institute for integrative biology of the cell (I2BC). Interested in Archaea, hyperthermophiles, DNA topology, topoisomerases.
Reposted by Tamara Basta
Mark your calendars for the next incarnation of the Biology and Physics of the Prokaryotic Chromosome meeting to be held in Paris on July 6-9, 2027.
See the web site for further information biophychrom2027.sciencesconf.org
See the web site for further information biophychrom2027.sciencesconf.org
The Biology and Physics of Prokaryotic Chromosomes VIII - Sciencesconf.org
Presentation
biophychrom2027.sciencesconf.org
February 5, 2026 at 8:58 AM
Mark your calendars for the next incarnation of the Biology and Physics of the Prokaryotic Chromosome meeting to be held in Paris on July 6-9, 2027.
See the web site for further information biophychrom2027.sciencesconf.org
See the web site for further information biophychrom2027.sciencesconf.org
Reposted by Tamara Basta
A reminder to sign up for the 2026 EMBO archaeal meeting im Cambridge: meetings.embo.org/event/26-arc.... Registration is open. We are looking forward to hosting you!
Molecular Biology of Archaea: Life Through the Prism of Archaea
In 1977, Woese and colleagues revealed Archaea as a distinct domain of life. Building on this insight, the discovery of Asgard archaea has strengthened the view that many hallmarks of eukaryotic cell…
meetings.embo.org
January 23, 2026 at 8:15 AM
A reminder to sign up for the 2026 EMBO archaeal meeting im Cambridge: meetings.embo.org/event/26-arc.... Registration is open. We are looking forward to hosting you!
Reposted by Tamara Basta
Iron Sulfides Produced by Thermococcales: An Iron Detoxification Mechanism enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
Iron Sulfides Produced by Thermococcales: An Iron Detoxification Mechanism
Thermococcales, archaea from hydrothermal vents, promote iron sulfide precipitation, enabling survival in iron-rich environments. Some cells become encrusted in pyrite and do not survive mineralizati...
enviromicro-journals.onlinelibrary.wiley.com
January 26, 2026 at 5:10 AM
Iron Sulfides Produced by Thermococcales: An Iron Detoxification Mechanism enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Tamara Basta
Calling all archaeal enthusiasts! 🔬🔥 From molecular machines to microbial communities, Archaea never fail to surprise us!
We are excited to announce the 2026 EMBO Workshop on the Molecular Biology of Archaea, 6–10 July in Cambridge, UK!
Sign up here: meetings.embo.org/event/26-arc...
#ArchaeaSky
We are excited to announce the 2026 EMBO Workshop on the Molecular Biology of Archaea, 6–10 July in Cambridge, UK!
Sign up here: meetings.embo.org/event/26-arc...
#ArchaeaSky
December 16, 2025 at 2:18 PM
Calling all archaeal enthusiasts! 🔬🔥 From molecular machines to microbial communities, Archaea never fail to surprise us!
We are excited to announce the 2026 EMBO Workshop on the Molecular Biology of Archaea, 6–10 July in Cambridge, UK!
Sign up here: meetings.embo.org/event/26-arc...
#ArchaeaSky
We are excited to announce the 2026 EMBO Workshop on the Molecular Biology of Archaea, 6–10 July in Cambridge, UK!
Sign up here: meetings.embo.org/event/26-arc...
#ArchaeaSky
Reposted by Tamara Basta
Are you a long-time fan of Archaea, an extremophile-phile, or are you simply curious?
Either way, we have good news.
We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July.
Sign up: meetings.embo.org/event/26-arc...
We look forward to seeing you in Cambridge, UK.
Please repost!
Either way, we have good news.
We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July.
Sign up: meetings.embo.org/event/26-arc...
We look forward to seeing you in Cambridge, UK.
Please repost!
Molecular Biology of Archaea: Life Through the Prism of Archaea
In 1977, Woese and colleagues revealed Archaea as a distinct domain of life. Building on this insight, the discovery of Asgard archaea has strengthened the view that many hallmarks of eukaryotic cell…
meetings.embo.org
December 16, 2025 at 12:00 PM
Are you a long-time fan of Archaea, an extremophile-phile, or are you simply curious?
Either way, we have good news.
We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July.
Sign up: meetings.embo.org/event/26-arc...
We look forward to seeing you in Cambridge, UK.
Please repost!
Either way, we have good news.
We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July.
Sign up: meetings.embo.org/event/26-arc...
We look forward to seeing you in Cambridge, UK.
Please repost!
Reposted by Tamara Basta
Are you a long-time fan of Archaea, an extremophile-phile, or are you simply curious?
Either way, we have good news.
We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July.
Sign up: meetings.embo.org/event/26-arc...
We look forward to seeing you in Cambridge, UK
Please repost!!
Either way, we have good news.
We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July.
Sign up: meetings.embo.org/event/26-arc...
We look forward to seeing you in Cambridge, UK
Please repost!!
meetings.embo.org
December 16, 2025 at 12:58 PM
Are you a long-time fan of Archaea, an extremophile-phile, or are you simply curious?
Either way, we have good news.
We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July.
Sign up: meetings.embo.org/event/26-arc...
We look forward to seeing you in Cambridge, UK
Please repost!!
Either way, we have good news.
We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July.
Sign up: meetings.embo.org/event/26-arc...
We look forward to seeing you in Cambridge, UK
Please repost!!
Reposted by Tamara Basta
Please also check out the excellent complementary work from Tamara Basta @tamarabasta.bsky.social and Laura Baranello’s group.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Localised activity of reverse gyrase at gene regulatory elements
DNA topoisomerases are essential enzymes found in all cells, where they regulate DNA supercoiling. Reverse gyrase (RG) is a unique type of topoisomerase that introduces positive supercoils into DNA an...
www.biorxiv.org
December 11, 2025 at 7:03 AM
Please also check out the excellent complementary work from Tamara Basta @tamarabasta.bsky.social and Laura Baranello’s group.
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reposted by Tamara Basta
Delighted to share our latest preprint on reverse gyrase, a unique topoisomerase found exclusively in thermophiles!
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Reverse gyrase and 3D genome architecture suppress hyperthermophile genome instability arising from horizontal gene transfer
Reverse gyrase (Rgy), a distinctive topoisomerase conserved in all hyperthermophiles, has the unique ability to introduce positive DNA supercoils. It has long been hypothesized that Rgy overwinds geno...
www.biorxiv.org
December 11, 2025 at 6:40 AM
Delighted to share our latest preprint on reverse gyrase, a unique topoisomerase found exclusively in thermophiles!
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Delighted to share our new preprint: www.biorxiv.org/content/10.6...
We address a longstanding question about the role of the topoisomerase reverse gyrase in hyperthermophiles. Great collaboration with Baranello and @tobiaswarnecke.bsky.social groups. #Archaeasky #Microsky
We address a longstanding question about the role of the topoisomerase reverse gyrase in hyperthermophiles. Great collaboration with Baranello and @tobiaswarnecke.bsky.social groups. #Archaeasky #Microsky
Localised activity of reverse gyrase at gene regulatory elements
DNA topoisomerases are essential enzymes found in all cells, where they regulate DNA supercoiling. Reverse gyrase (RG) is a unique type of topoisomerase that introduces positive supercoils into DNA an...
www.biorxiv.org
December 11, 2025 at 1:15 PM
Delighted to share our new preprint: www.biorxiv.org/content/10.6...
We address a longstanding question about the role of the topoisomerase reverse gyrase in hyperthermophiles. Great collaboration with Baranello and @tobiaswarnecke.bsky.social groups. #Archaeasky #Microsky
We address a longstanding question about the role of the topoisomerase reverse gyrase in hyperthermophiles. Great collaboration with Baranello and @tobiaswarnecke.bsky.social groups. #Archaeasky #Microsky
Reposted by Tamara Basta
Open FSEP position in our team 📣
Nous recrutons un/e Ingénieur/e d’étude en biologie.
Profil : être titulaire d’un poste permanent au CNRS (IE) et avoir envie d’étudier la chromatine bactérienne 😉
Date limite : jeudi 15 janvier.
Détails et candidature ici :
mobiliteinterne.cnrs.fr/ords/afip/ow...
Nous recrutons un/e Ingénieur/e d’étude en biologie.
Profil : être titulaire d’un poste permanent au CNRS (IE) et avoir envie d’étudier la chromatine bactérienne 😉
Date limite : jeudi 15 janvier.
Détails et candidature ici :
mobiliteinterne.cnrs.fr/ords/afip/ow...
Détails de la fonction choisie
mobiliteinterne.cnrs.fr
December 8, 2025 at 12:52 PM
Open FSEP position in our team 📣
Nous recrutons un/e Ingénieur/e d’étude en biologie.
Profil : être titulaire d’un poste permanent au CNRS (IE) et avoir envie d’étudier la chromatine bactérienne 😉
Date limite : jeudi 15 janvier.
Détails et candidature ici :
mobiliteinterne.cnrs.fr/ords/afip/ow...
Nous recrutons un/e Ingénieur/e d’étude en biologie.
Profil : être titulaire d’un poste permanent au CNRS (IE) et avoir envie d’étudier la chromatine bactérienne 😉
Date limite : jeudi 15 janvier.
Détails et candidature ici :
mobiliteinterne.cnrs.fr/ords/afip/ow...
Reposted by Tamara Basta
Last chance to apply for one of the LSI PhD projects intake Sept 2026! Deadline tomorrow, 26.11.2025, noon. www.exeter.ac.uk/research/ins... @exeter.ac.uk @lsiexeter.bsky.social
November 25, 2025 at 5:07 PM
Last chance to apply for one of the LSI PhD projects intake Sept 2026! Deadline tomorrow, 26.11.2025, noon. www.exeter.ac.uk/research/ins... @exeter.ac.uk @lsiexeter.bsky.social
Reposted by Tamara Basta
📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social
www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
November 9, 2025 at 5:20 PM
📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social
www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!
Reposted by Tamara Basta
A very nice review on my favorite archaea. The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology journals.asm.org/doi/10.1128/...
The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology
The exploration of life in extreme environments gained prominence with Thomas Brock’s
“Life at High Temperatures” (1), and his subsequent isolation of Thermus aquaticus with Hudson Freeze in 1969 (2) ...
journals.asm.org
November 6, 2025 at 9:39 AM
A very nice review on my favorite archaea. The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology journals.asm.org/doi/10.1128/...
Reposted by Tamara Basta
New article online: Modulation of archaeal hypernucleosome structure and stability by Mg2+
In this work, we dissect the effects of Mg2+ on hypernucleosomes formed by the canonical histones from M. fervidus (HMfA and HMfB) and T. kodakarensis (HTkA and HTkB).
www.sciencedirect.com/science/arti...
In this work, we dissect the effects of Mg2+ on hypernucleosomes formed by the canonical histones from M. fervidus (HMfA and HMfB) and T. kodakarensis (HTkA and HTkB).
www.sciencedirect.com/science/arti...
Modulation of archaeal hypernucleosome structure and stability by Mg2+
DNA-wrapping histone proteins play a central role in chromatin organization, gene expression and regulation in most eukaryotes and archaea. While the …
www.sciencedirect.com
November 6, 2025 at 7:53 AM
New article online: Modulation of archaeal hypernucleosome structure and stability by Mg2+
In this work, we dissect the effects of Mg2+ on hypernucleosomes formed by the canonical histones from M. fervidus (HMfA and HMfB) and T. kodakarensis (HTkA and HTkB).
www.sciencedirect.com/science/arti...
In this work, we dissect the effects of Mg2+ on hypernucleosomes formed by the canonical histones from M. fervidus (HMfA and HMfB) and T. kodakarensis (HTkA and HTkB).
www.sciencedirect.com/science/arti...
Reposted by Tamara Basta
The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology journals.asm.org/doi/10.1128/...
The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology
The exploration of life in extreme environments gained prominence with Thomas Brock’s
“Life at High Temperatures” (1), and his subsequent isolation of Thermus aquaticus with Hudson Freeze in 1969 (2) ...
journals.asm.org
November 5, 2025 at 8:06 PM
The Thermococcales as a model system: historical perspectives and emerging tools | Journal of Bacteriology journals.asm.org/doi/10.1128/...
Reposted by Tamara Basta
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
October 21, 2025 at 9:16 PM
Reposted by Tamara Basta
Our work on ribosome hibernation in archaea is out!
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
October 13, 2025 at 4:26 PM
Our work on ribosome hibernation in archaea is out!
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
We identified Hib, a new hibernation factor broadly distributed across archaea.
Check out the preprint 👉 biorxiv.org/content/10.1101/2025.10.11.676729v1
(1/🧵)
Reposted by Tamara Basta
ribosomologists take note 👇
archaeal ribosome hibernation factors aRDF, Dri, ...and now: Hib (see ALT)
#Archaea #ArchaeaSky
archaeal ribosome hibernation factors aRDF, Dri, ...and now: Hib (see ALT)
#Archaea #ArchaeaSky
October 12, 2025 at 7:13 PM
ribosomologists take note 👇
archaeal ribosome hibernation factors aRDF, Dri, ...and now: Hib (see ALT)
#Archaea #ArchaeaSky
archaeal ribosome hibernation factors aRDF, Dri, ...and now: Hib (see ALT)
#Archaea #ArchaeaSky
Reposted by Tamara Basta
Out in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail
This structure of an archaeal tailed virus (arTV) provides detailed insights into arTV assembly and infection mechanisms.
www.science.org
October 6, 2025 at 11:31 AM
Out in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
Reposted by Tamara Basta
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
October 7, 2025 at 6:20 AM
Reposted by Tamara Basta
Du 2 au 5 décembre 2025, Université Paris-Cité
Congrès « Enzymes, Proteolysis & Metabolism at the crossroads of Biochemistry », premier congrès commun de trois Groupes Thématiques de la SFBBM.
gts-sfbbm-2025.sciencesconf.org?lang=fr
Congrès « Enzymes, Proteolysis & Metabolism at the crossroads of Biochemistry », premier congrès commun de trois Groupes Thématiques de la SFBBM.
gts-sfbbm-2025.sciencesconf.org?lang=fr
Enzymes, Proteolysis & Metabolism at the crossroads of Biochemistry - Sciencesconf.org
Présentation
gts-sfbbm-2025.sciencesconf.org
October 7, 2025 at 8:10 AM
Du 2 au 5 décembre 2025, Université Paris-Cité
Congrès « Enzymes, Proteolysis & Metabolism at the crossroads of Biochemistry », premier congrès commun de trois Groupes Thématiques de la SFBBM.
gts-sfbbm-2025.sciencesconf.org?lang=fr
Congrès « Enzymes, Proteolysis & Metabolism at the crossroads of Biochemistry », premier congrès commun de trois Groupes Thématiques de la SFBBM.
gts-sfbbm-2025.sciencesconf.org?lang=fr
Reposted by Tamara Basta
Become my colleague @oxfordbiochemistry.bsky.social !
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism
my.corehr.com/pls/uoxrecru...
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism
my.corehr.com/pls/uoxrecru...
Job Details
my.corehr.com
September 29, 2025 at 9:25 AM
Become my colleague @oxfordbiochemistry.bsky.social !
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism
my.corehr.com/pls/uoxrecru...
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism
my.corehr.com/pls/uoxrecru...
Reposted by Tamara Basta
#BioPhyChrom25 gala dinner at the 14th century #Hospitium venue in York, and @agnesnoy.bsky.social talk. Lots of discussion and ideas for BioPhyChrom2027… Great vibes and atmosphere!
@biophychrom.bsky.social @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social 🧬
@biophychrom.bsky.social @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social 🧬
September 18, 2025 at 11:14 PM
#BioPhyChrom25 gala dinner at the 14th century #Hospitium venue in York, and @agnesnoy.bsky.social talk. Lots of discussion and ideas for BioPhyChrom2027… Great vibes and atmosphere!
@biophychrom.bsky.social @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social 🧬
@biophychrom.bsky.social @damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @biochemsoc.bsky.social 🧬
Reposted by Tamara Basta
That’s a wrap for The Biology and Physics of Prokaryotic Chromosomes VII 2025. A big thank you to all those who attended 🧪 #BioPhyChrom2025 #BiochemEvents
September 19, 2025 at 8:50 AM
That’s a wrap for The Biology and Physics of Prokaryotic Chromosomes VII 2025. A big thank you to all those who attended 🧪 #BioPhyChrom2025 #BiochemEvents
Reposted by Tamara Basta
#Biophychrom2025 is over, but we spent four exciting days discussing the biology and physics of prokaryotic chromosomes. Congratulations to all the attendees for making this conference a success.
@biochemsoc.bsky.social
@danielabarilla.bsky.social
@graingerlab.bsky.social
@damelab.bsky.social
@biochemsoc.bsky.social
@danielabarilla.bsky.social
@graingerlab.bsky.social
@damelab.bsky.social
September 19, 2025 at 5:57 PM
#Biophychrom2025 is over, but we spent four exciting days discussing the biology and physics of prokaryotic chromosomes. Congratulations to all the attendees for making this conference a success.
@biochemsoc.bsky.social
@danielabarilla.bsky.social
@graingerlab.bsky.social
@damelab.bsky.social
@biochemsoc.bsky.social
@danielabarilla.bsky.social
@graingerlab.bsky.social
@damelab.bsky.social