Sunny Dai
sunnydai.bsky.social
Sunny Dai
@sunnydai.bsky.social
Light sheet application Copenhagen | 3D imaging | Tissue clearing 🩵
Reposted by Sunny Dai
🎉 I am very glad to share that our paper on the rapid isotropic light-sheet microscope has just been published in Nature Biotechnology @natbiotech.nature.com.

🔗 Read the full article:
www.nature.com/articles/s41...
Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue - Nature Biotechnology
A light-sheet microscope built from off-the-shelf components enables high-resolution clear tissue imaging.
www.nature.com
November 14, 2025 at 9:27 PM
Reposted by Sunny Dai
Happy to see our paper “Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue” in @natbiotech.nature.com – with Tobias Moser’s lab from @unimedizin-goe.bsky.social and @janwenzel.bsky.social
www.nature.com/articles/s41...

#microscopy #lightsheet
November 14, 2025 at 4:41 PM
Reposted by Sunny Dai
I’ll be speaking about the mechanical development of crocodile and tortoise head scales next Wednesday at 4pm for the @tlmcambridge.bsky.social seminar series. Subscribe to the mailing list to hear more about my work, and that of @maltemederacke.bsky.social!

lists.cam.ac.uk/sympa/subscr...
October 30, 2025 at 11:39 AM
Are those mouse brain light sheet images at Erykah Badu's concert in London?? 🤯
October 29, 2025 at 10:54 PM
Reposted by Sunny Dai
How are human brain regions connected? Are the connecting axons thicker and more myelinated the longer these connecting fibers are?

In our recent paper we find that indeed, they are! Read the skeetorial below ⬇️⬇️⬇️

plos.io/4mq5tOy
#neuroscience #neuroskyence #whitematter #deeplearning
August 21, 2025 at 12:39 PM
Reposted by Sunny Dai
#LISH25 day 10 ushered in by Claudia Gerri from @mpi-cbg.de introducing us to the wonderful world of mammalian early embryo development, implantation and #placenta interactions. Showing light sheet data from ex #LoPaT - Michi Burkon 💕. Walk-up song with Italian flair came with sweets.
August 20, 2025 at 7:19 AM
Reposted by Sunny Dai
It’s Sunday, but #LISH25 goes on with Matteo Rauzi presentation on using light sheet to study #Morphogenesis of #flies and #sea_urchins. Matteo had not one but two walk-up songs! #RockyBalboa 🥊
August 17, 2025 at 9:13 AM
Reposted by Sunny Dai
a second rendering for #fluorescencefriday
August 15, 2025 at 6:32 PM
This was magical — @loicaroyer.bsky.social live on piano @mpi-cbg.de. Made my day! It’s always amazing to learn about unexpected talents apart from the amazing science.
August 15, 2025 at 9:42 AM
Love these names 😆
We got our #LISH2025 Team names:

Holy de Broglies
Liv & Dye
SPIMply the best
Specimen Illuminati
August 15, 2025 at 9:42 AM
Reposted by Sunny Dai
For the day five of #LISH25 Jan Huisken comes home, to @mpi-cbg.de, to show us what his latest project, the #Flamingo microscope can do. Walk up song featured stunning photography of birds - all taken by Jan who is the imager all the way.
August 15, 2025 at 7:13 AM
Reposted by Sunny Dai
An AD mouse brain with therapeutic antibody (in blue) and smooth muscle cells (in yellow).The first attempt, but quite successful. Thanks to @dvonwangenheim.bsky.social
#LISH25
August 14, 2025 at 7:12 PM
Reposted by Sunny Dai
Pan-ASLM: a high-resolution and large field-of-view light sheet microscope for Expansion Microscopy www.biorxiv.org/content/10.1...
Pan-ASLM: a high-resolution and large field-of-view light sheet microscope for Expansion Microscopy
Expansion microscopy, a super-resolution fluorescence microscopy technique in which samples are expanded up to ∼8,000 times (after 20-fold expansion) their original volume, places high demands on the ...
www.biorxiv.org
August 14, 2025 at 5:46 PM
Reposted by Sunny Dai
My undergrad Inword got some really cool data this week, and I can't think of a better way to celebrate #fluorescencefriday than to share it. She injected oligomeric amyloid-B (red) and it caused these pulses of tracer leakage throughout the brain (turquoise) 1.5 days later. #BBB #zebrafish
July 12, 2025 at 12:27 AM
Reposted by Sunny Dai
Excited to share our new research in @cp-iscience.bsky.social! We reveal that tortoise head scales are sculpted through two distinct developmental processes - chemical signalling and mechanical folding 🐢🔬🧪
@lanevol.bsky.social @genevunige.bsky.social

www.cell.com/iscience/ful...
Chemical and mechanical patterning of tortoise skin scales occur in different regions of the head
Biological sciences; Zoology; Evolutionary biology
www.cell.com
June 4, 2025 at 2:39 PM
Beautiful 💙🩵
For something that's arguably the basis of life itself, not that many artists engage with mitosis. Thank goodness there's me artologica.substack.com/p/mitosis-mo... 🐡🦠🧪🎨
Mitosis, Mon Amour
Cells keep on dividing and I keep on painting them
artologica.substack.com
July 3, 2025 at 4:27 PM
Reposted by Sunny Dai
When microscopy meets MRI at MINDs with @neuroak.bsky.social
#fluorescenceFriday
June 20, 2025 at 10:13 AM
Reposted by Sunny Dai
OmiCLIP #Visualomics

An amazing Histology (HE) - #SpatialTranscriptomics foundation model

An ST-bank
2.2 M image-Visium pairs
1007 tissue samples
32 organs

Loki PredEx
HE-to-spatial gene expression
vs Hist2ST HisToGene BLEEP mclSTExp

@natmethods.nature.com 2025
www.nature.com/articles/s41...
June 9, 2025 at 11:48 AM
Reposted by Sunny Dai
The @embo.org practical course on #lightsheet #microscopy is back!

Join us in #Dresden for 2 weeks with #your #samples, try the complete line-up of #lightsheet microscopes, tackle big data image analysis, sample prep, OA hardware & much more

Apply now!

Repost 🙏

meetings.embo.org/event/25-lsm
Light sheet microscopy
Light sheet microscopy is a technology that enables near-isotropic imaging of large biological specimens over time. It opens new avenues to study biological processes with unprecedented imaging speed…
meetings.embo.org
April 15, 2025 at 8:33 AM
Reposted by Sunny Dai
#legoptical Episode 3: An italian twist. In 1997, Franco Quercioli and his colleagues published in SPIE an article entitled: “Play optics with Lego” introducing for the first tie the use of LEGO bricks in setting up an optical instrument!
opg.optica.org/ao/abstract....
March 31, 2025 at 1:46 PM
Reposted by Sunny Dai
After the course, some of these microscopes stay in the beautiful @pasteuredu.bsky.social for a week, and the companies will welcome you on request to organize demos.

Interested? All information on how to book a demo is here:

research.pasteur.fr/en/event/sym...
Symposium and Workshop "Pushing the frontiers of biological imaging 2025" - Research
The Pasteur Education center and the Pasteur Advanced Light Microscopy Initiative organize a 1/2 day symposium dedicated to recent advances in Life-Sciences and Light Microscopy. The symposium is foll...
research.pasteur.fr
March 18, 2025 at 4:11 PM
Loving this series!! Got to show off this miniMOC that my friend built 😊🥰
March 17, 2025 at 10:24 AM
Reposted by Sunny Dai
Sugars labeled in a zebrafish embryo. Credit to Holly Aaron & @carolynbertozzi.bskyverified.social. #ZebrafishZunday 🧪
March 2, 2025 at 1:51 PM
Reposted by Sunny Dai
@john-haug.bsky.social and I are getting ready to announce a DIY, open-source light-sheet microscope designed for high-resolution, sub-cellular imaging. Here is one sneak peak of some raw data! #COMPASS
March 4, 2025 at 5:59 PM