Elias Spiliotis
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septinlab.bsky.social
Elias Spiliotis
@septinlab.bsky.social
Professor of Cell Biology (University of Virginia), Research Scientist. Science, music, sports and politics. Opinions are my own and not of my lab or university.
Amazing to see him live with Patti a few weeks ago.

And dumbfounded to discover - also a few weeks ago - that he was the curator of the legendary 60s psych comp: Nuggets!

Had no idea.
Happy 79th Birthday Lenny Kaye, American guitarist, composer, and writer, known for his work with the Patti Smith Group and his contributions to music magazines, born on this day in 1946, NYC

Photo by Gus Stewart (1976)

#punk #punks #punkrock #punklegends #lennykaye #history #punkrockhistory #otd
December 27, 2025 at 10:42 PM
Tango forever!

Post 2000 balls might as well be for a different sport…
December 26, 2025 at 5:09 PM
Nailed it!
Look, I'm sure that Nolan's adaptation of "The Odyssey" will be fun, but I highly doubt it will be as good as the original.
December 25, 2025 at 11:42 PM
"Waymo's self-driving cars were put on pause by the company after the autonomous vehicles were baffled by the lack of traffic lights, getting stuck at intersections and causing traffic jams"

Life comes at you fast! Famous last words.

www.sfgate.com/bayarea/arti...
Thousands in San Francisco still without power as PG&E outage drags on
Tens of thousands of San Franciscans remain without power on Sunday morning.
www.sfgate.com
December 21, 2025 at 7:34 PM
New ideas are needed for new technologies.

It all starts in between the ears.

Think before you do
“Progress in science depends on new techniques, new discoveries and new ideas, probably in that order. “
— Sydney Brenner
December 17, 2025 at 12:52 PM
I better dust off my undergraduate thesis data on Methanococcus igneus, and di-myo-inositol-1,19-phosphate...
Are you a long-time fan of Archaea, an extremophile-phile, or are you simply curious?

Either way, we have good news.
We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July.

Sign up: meetings.embo.org/event/26-arc...

We look forward to seeing you in Cambridge, UK.

Please repost!
Molecular Biology of Archaea: Life Through the Prism of Archaea
In 1977, Woese and colleagues revealed Archaea as a distinct domain of life. Building on this insight, the discovery of Asgard archaea has strengthened the view that many hallmarks of eukaryotic cell…
meetings.embo.org
December 17, 2025 at 12:42 PM
Reposted by Elias Spiliotis
I shouldn’t have to share this article as much as I do. Sending condolences to all friends and family and loved ones from the Brown Shooting today.

www.newsweek.com/2025/07/18/f...
Why Flavor Flav says the US must ban firearms now | Opinion
The lack of U.S. gun laws has created a violence epidemic unlike anywhere else on Earth. This is domestic errorism
www.newsweek.com
December 14, 2025 at 4:24 AM
Reposted by Elias Spiliotis
💥I am excited to present our first research paper from the lab about caveolae lipid trafficking 🎉 Led by my fantastic PhD candidate @estherocket.bsky.social

Here we looked into caveolae mediated dietary lipid uptake and how this process is mechanistically facilitated 👇 1/n
Lipid-induced Caveolin1-Lipid droplet trafficking is associated with lipid droplet growth https://www.biorxiv.org/content/10.64898/2025.12.10.693432v1
December 11, 2025 at 7:08 AM
I made a new friend @ #cellbio2025
December 11, 2025 at 12:31 AM
Philly legal shark holiday spirit!
December 7, 2025 at 4:14 PM
Check us out @ #cellbio2025

Sunday:
Board 143: Poster by Franklin on machanoprotection of the nucleus 🔥

Board 150: Poster by Noor on GSK3b regulating microtubule vs actin septin association
🏆

Monday:
Talk by Noor at 11:15 am Rm 115

Tuesday
Board 233: Poster by TJ on neuronal ER-PM contacts
🦅
December 7, 2025 at 1:48 PM
Reposted by Elias Spiliotis
Lerche, Mathieu, @johannaivaska.bsky.social @ivaskalab.bsky.social et al. reveal that newly synthesized #integrins can bypass the Golgi to be actively delivered to specific plasma membrane regions, where they enhance cell protrusion and #adhesion. rupress.org/jcb/article/...
December 2, 2025 at 6:30 PM
Reposted by Elias Spiliotis
World AIDS Day memory

In 1993 or 4, I sat in a meeting in the Johns Hopkins medical board room for a discussion about building another hospital to treat patients who could not be accommodated because Hopkins would be overwhelmed with AIDS patients.

1/2
December 2, 2025 at 8:34 AM
😱
HBOMax has started showing a 'remastered' 4K Mad Men and they’ve messed things up so during Roger’s oyster vomit scene you can now see the crew men with the vomit hose on the right
December 2, 2025 at 9:35 PM
Reposted by Elias Spiliotis
Today, our animation synthesizing decades of research on actin-mediated endocytosis in budding yeast was published:
journals.biologists.com/jcs/article/...

The result of a fantastic Iwasa-Drubin lab collaboration.

@margotriggi.bsky.social @jiwasa.bsky.social
movie.biologists.com/video/10.124...
December 2, 2025 at 9:02 PM
Blessed to see Patti Smith live in DC late night at 78 years young.

The raw intensity never leaves the bodies of these old dog punks!

Fury, poetry, rock’n’roll
November 30, 2025 at 1:48 AM
Eminem joining Jack White might be the first garage rock-hip hop fusion... (at least that I am aware of)
Courtesy of thanksgiving football games becoming mini superbowls
www.youtube.com/watch?v=Pk5l...
Jack White FULL Thanksgiving Halftime Show
YouTube video by NFL
www.youtube.com
November 28, 2025 at 12:14 PM
Timely NYTimes post for #CellBio2025

10 more days until ASCBers weigh in on the debate!

www.nytimes.com/2025/11/24/d...
Michelin Honored the Cheesesteak. Not All Philadelphians Cheered.
www.nytimes.com
November 26, 2025 at 5:08 PM
Reposted by Elias Spiliotis
new historical marker up in town!
November 26, 2025 at 3:24 PM
Guess no time to digest that turkey. Back on the grant resubmission wagon...
November 24, 2025 at 8:29 PM
New septin paper by our next door lab neighbors @ebrahim-lab.bsky.social, and on the cover of JCI Insight no less.

Septin 9 reinforces intestinal epithelial junctions, preventing leaky gut and inflammation.

Check it out!
This issue’s Cover: @ebrahim-lab.bsky.social @dominikrobak.bsky.social& team report on the septin cytoskeleton at apical junctions of intestinal epithelial cells, whereby it maintains barrier integrity & protects from inflammation: insight.jci.org/articles/vie...
November 24, 2025 at 7:45 PM
Reposted by Elias Spiliotis
Revealing acute consequences of rapid degradation of synaptic fusion proteins at individual synapses using Auxin-Inducible Degron 2 technology
www.nature.com/articles/s42...
November 22, 2025 at 7:59 PM
Pavement never broke into 90s alterna/MTV mainstream with their quirky tongue-in-cheek and off kilter song writing, but expanded the borders, possibilities and cred of a newly emerging indie rock DIY scene.

Formed by UVA alums Stephen Malkmus and Scott Kannberg.

www.youtube.com/watch?v=w2Ww...
Pavement- "Harness Your Hopes" (Official Music Video)
YouTube video by Pavement
www.youtube.com
November 22, 2025 at 12:09 PM