David Seki
@sekid.bsky.social
Senior PostDoc at Cluster of Excellence “Microbiomes drive Planetary Health“
Human Gut Microbial Ecology, Pharmacology, Neonatal Gut-Immune-Brain Axis Development.
Human Gut Microbial Ecology, Pharmacology, Neonatal Gut-Immune-Brain Axis Development.
Reposted by David Seki
Excited to share our @cp-cellhostmicrobe.bsky.social led by Magda showing how Bif has co-evolved with different animal hosts 🐒🐭🐷🐦
Key takeaways:
🔹 Host ancestry + diet shape Bif evolution
🔹 Mammals enriched for carb-busting enzymes
🔹 Untapped diversity in non-human hosts = new probiotic potential
Key takeaways:
🔹 Host ancestry + diet shape Bif evolution
🔹 Mammals enriched for carb-busting enzymes
🔹 Untapped diversity in non-human hosts = new probiotic potential
Bifido adaptations across hosts
@halllab.bsky.social survey insects, reptiles, birds & mammals to uncover how Bifidobacterium adapts to hosts. Bifidobacterium & host exhibit strong co-phylogenetic associations, driven by vertical transmission & dietary selection
www.cell.com/cell-host-mi...
@halllab.bsky.social survey insects, reptiles, birds & mammals to uncover how Bifidobacterium adapts to hosts. Bifidobacterium & host exhibit strong co-phylogenetic associations, driven by vertical transmission & dietary selection
www.cell.com/cell-host-mi...
Host-specific microbiome and genomic signatures in Bifidobacterium reveal co-evolutionary and functional adaptations across diverse animal hosts
Bifidobacterium are beneficial members of the microbiota across animal hosts. Kujawska
et al. demonstrate that bifidobacteria have likely co-evolved more closely with mammals,
particularly primates, a...
www.cell.com
September 11, 2025 at 2:49 PM
Excited to share our @cp-cellhostmicrobe.bsky.social led by Magda showing how Bif has co-evolved with different animal hosts 🐒🐭🐷🐦
Key takeaways:
🔹 Host ancestry + diet shape Bif evolution
🔹 Mammals enriched for carb-busting enzymes
🔹 Untapped diversity in non-human hosts = new probiotic potential
Key takeaways:
🔹 Host ancestry + diet shape Bif evolution
🔹 Mammals enriched for carb-busting enzymes
🔹 Untapped diversity in non-human hosts = new probiotic potential
Reposted by David Seki
Reposted by David Seki
📢 New paper in @nature.com
Microbes rock 🎸🤘 with sulfide and iron minerals
I am very excited to share our recent study, which describes a previously unknown microbial energy metabolism ⚡⚡⚡🦠🧫⚡⚡⚡
🆕 Microbial iron oxide respiration coupled to sulfide oxidation - MISO
www.nature.com/articles/s41...
Microbes rock 🎸🤘 with sulfide and iron minerals
I am very excited to share our recent study, which describes a previously unknown microbial energy metabolism ⚡⚡⚡🦠🧫⚡⚡⚡
🆕 Microbial iron oxide respiration coupled to sulfide oxidation - MISO
www.nature.com/articles/s41...
Microbial iron oxide respiration coupled to sulfide oxidation - Nature
Genomic and biochemical analyses of prokaryotic sulfur metabolism identify diverse microorganisms with the capacity to oxidize sulfide using iron(iii).
www.nature.com
August 27, 2025 at 8:17 PM
📢 New paper in @nature.com
Microbes rock 🎸🤘 with sulfide and iron minerals
I am very excited to share our recent study, which describes a previously unknown microbial energy metabolism ⚡⚡⚡🦠🧫⚡⚡⚡
🆕 Microbial iron oxide respiration coupled to sulfide oxidation - MISO
www.nature.com/articles/s41...
Microbes rock 🎸🤘 with sulfide and iron minerals
I am very excited to share our recent study, which describes a previously unknown microbial energy metabolism ⚡⚡⚡🦠🧫⚡⚡⚡
🆕 Microbial iron oxide respiration coupled to sulfide oxidation - MISO
www.nature.com/articles/s41...
Reposted by David Seki
Reposted by David Seki
Two vaccine candidates using mRNA technology elicit a potent immune response against HIV
go.nature.com/4ov7WZI
go.nature.com/4ov7WZI
mRNA vaccines for HIV trigger strong immune response in people
Results from early-stage trial show that 80% of participants who received one of two HIV vaccine candidates produced antibodies against viral proteins.
go.nature.com
August 1, 2025 at 8:40 AM
Two vaccine candidates using mRNA technology elicit a potent immune response against HIV
go.nature.com/4ov7WZI
go.nature.com/4ov7WZI
Reposted by David Seki
An analysis in Nature Ecology & Evolution shows that near-national-scale losses of bird diversity greatly exceed losses recorded at the local scale in Colombia, suggesting that extrapolations from local studies will severely underestimate biodiversity losses. go.nature.com/3HbRv3s 🧪
July 31, 2025 at 10:52 PM
An analysis in Nature Ecology & Evolution shows that near-national-scale losses of bird diversity greatly exceed losses recorded at the local scale in Colombia, suggesting that extrapolations from local studies will severely underestimate biodiversity losses. go.nature.com/3HbRv3s 🧪
Excited to finally share results from my first post-doc @halllab.bsky.social 🫡
E.coli commonly occurs in infant gut microbiota, yet its role during healthy development has been disregarded. In our pre-print, we reveal its fundamental involvement in HMO-degradation.
www.biorxiv.org/content/10.1...
E.coli commonly occurs in infant gut microbiota, yet its role during healthy development has been disregarded. In our pre-print, we reveal its fundamental involvement in HMO-degradation.
www.biorxiv.org/content/10.1...
www.biorxiv.org
April 9, 2025 at 3:12 PM
Excited to finally share results from my first post-doc @halllab.bsky.social 🫡
E.coli commonly occurs in infant gut microbiota, yet its role during healthy development has been disregarded. In our pre-print, we reveal its fundamental involvement in HMO-degradation.
www.biorxiv.org/content/10.1...
E.coli commonly occurs in infant gut microbiota, yet its role during healthy development has been disregarded. In our pre-print, we reveal its fundamental involvement in HMO-degradation.
www.biorxiv.org/content/10.1...
Reposted by David Seki
Excited to share our latest, out today in @naturemicrobiol.bsky.social Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium www.nature.com/articles/s41... @idpittstop.bsky.social
Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium - Nature Microbiology
Genomic and functional analyses of healthcare-associated vancomycin-resistant Enterococcus faecium reveal that bacteriocin T8 is enriched in emergent lineages and provides a competitive advantage in v...
www.nature.com
March 21, 2025 at 1:46 PM
Excited to share our latest, out today in @naturemicrobiol.bsky.social Bacteriocin production facilitates nosocomial emergence of vancomycin-resistant Enterococcus faecium www.nature.com/articles/s41... @idpittstop.bsky.social
Reposted by David Seki
Interested in the influence of the infant microbiome on health? Quickly interrogating non-model organisms using omic approaches?
A new publication, describing genome-scale resources in bifidobacteria, is now available online: doi.org/10.1016/j.ce...
#microbiome #microsky
A new publication, describing genome-scale resources in bifidobacteria, is now available online: doi.org/10.1016/j.ce...
#microbiome #microsky
March 13, 2025 at 10:35 PM
Interested in the influence of the infant microbiome on health? Quickly interrogating non-model organisms using omic approaches?
A new publication, describing genome-scale resources in bifidobacteria, is now available online: doi.org/10.1016/j.ce...
#microbiome #microsky
A new publication, describing genome-scale resources in bifidobacteria, is now available online: doi.org/10.1016/j.ce...
#microbiome #microsky
Reposted by David Seki
This week @science.org Sarfatis, Moffitt et al. from @bostonchildrens.bsky.social @harvardmed.bsky.social @broadinstitute.org
Highly multiplexed spatial transcriptomics in bacteria | Science www.science.org/doi/10.1126/...
#microsky #microbial #microbiology #genomics
#transcriptomic 🦠🧫
Highly multiplexed spatial transcriptomics in bacteria | Science www.science.org/doi/10.1126/...
#microsky #microbial #microbiology #genomics
#transcriptomic 🦠🧫
Highly multiplexed spatial transcriptomics in bacteria
Single-cell decisions made in complex environments underlie many bacterial phenomena. Image-based transcriptomics approaches offer an avenue to study such behaviors, yet these approaches have been hin...
www.science.org
January 24, 2025 at 4:30 AM
This week @science.org Sarfatis, Moffitt et al. from @bostonchildrens.bsky.social @harvardmed.bsky.social @broadinstitute.org
Highly multiplexed spatial transcriptomics in bacteria | Science www.science.org/doi/10.1126/...
#microsky #microbial #microbiology #genomics
#transcriptomic 🦠🧫
Highly multiplexed spatial transcriptomics in bacteria | Science www.science.org/doi/10.1126/...
#microsky #microbial #microbiology #genomics
#transcriptomic 🦠🧫
Reposted by David Seki
Excited to share our opinion piece with the KC Huang Lab.
Check it out here:
Harnessing gut microbial communities to unravel microbiome functions
doi.org/10.1016/j.mi...
@typaslab.bsky.social
Check it out here:
Harnessing gut microbial communities to unravel microbiome functions
doi.org/10.1016/j.mi...
@typaslab.bsky.social
January 13, 2025 at 3:08 PM
Excited to share our opinion piece with the KC Huang Lab.
Check it out here:
Harnessing gut microbial communities to unravel microbiome functions
doi.org/10.1016/j.mi...
@typaslab.bsky.social
Check it out here:
Harnessing gut microbial communities to unravel microbiome functions
doi.org/10.1016/j.mi...
@typaslab.bsky.social
Reposted by David Seki
Delighted to share the first peer-reviewed paper from our team @camvetschool.bsky.social where we investigate the ecological dynamics of Enterobacteriaceae in the human gut #microbiome: www.nature.com/articles/s41... @naturemicrobiol.bsky.social
Ecological dynamics of Enterobacteriaceae in the human gut microbiome across global populations - Nature Microbiology
Assessing more than 12,000 metagenomic samples from across the world using computational approaches, the authors determined interactions between species that co-colonize or co-exclude Enterobacteriace...
www.nature.com
January 10, 2025 at 10:06 AM
Delighted to share the first peer-reviewed paper from our team @camvetschool.bsky.social where we investigate the ecological dynamics of Enterobacteriaceae in the human gut #microbiome: www.nature.com/articles/s41... @naturemicrobiol.bsky.social
Reposted by David Seki
Host metabolism balances microbial regulation of bile acid signalling | @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Host metabolism balances microbial regulation of bile acid signalling - Nature
A family of host-derived bile acid–methylcysteamine conjugates functions as FXR antagonists, forming part of a microbiota-dependent metabolic network that regulates FXR-dependent physiology.
www.nature.com
January 10, 2025 at 6:31 PM
Host metabolism balances microbial regulation of bile acid signalling | @nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by David Seki
1/ 🚨 New preprint alert! 🚨 We’re thrilled to share our latest work exploring microbiome & genomic #Bifidobacterium co-evolutionary & functional signatures across diverse animal hosts. This has been a long time coming, & huge credit to Magda for her incredible hard work as first author! 🐾✨👇
Host-specific microbiome and genomic signatures in Bifidobacterium reveal co-evolutionary and functional adaptations across diverse animal hosts
Animal hosts harbour divergent microbiota, including various Bifidobacterium species and strains, yet their evolutionary relationships, and functional adaptions remain understudied. By integrating tax...
doi.org
January 11, 2025 at 10:11 AM
1/ 🚨 New preprint alert! 🚨 We’re thrilled to share our latest work exploring microbiome & genomic #Bifidobacterium co-evolutionary & functional signatures across diverse animal hosts. This has been a long time coming, & huge credit to Magda for her incredible hard work as first author! 🐾✨👇
Reposted by David Seki
🚨 PhD Opportunity @halllab.bsky.social!
🔬 Decoding Early Life Microbiota & Host Interactions
🧬 Ideal for those with bioinformatics/microbiome experience
🌍 Open to international candidates (MSCA mobility rules apply).
📅 Deadline: 18th Dec
🌐 Apply now: www.findaphd.com/phds/project...
🔬 Decoding Early Life Microbiota & Host Interactions
🧬 Ideal for those with bioinformatics/microbiome experience
🌍 Open to international candidates (MSCA mobility rules apply).
📅 Deadline: 18th Dec
🌐 Apply now: www.findaphd.com/phds/project...
Decoding Early Life Microbiota and Host Interactions at University of Birmingham on FindAPhD.com
PhD Project - Decoding Early Life Microbiota and Host Interactions at University of Birmingham, listed on FindAPhD.com
www.findaphd.com
December 6, 2024 at 8:41 AM
🚨 PhD Opportunity @halllab.bsky.social!
🔬 Decoding Early Life Microbiota & Host Interactions
🧬 Ideal for those with bioinformatics/microbiome experience
🌍 Open to international candidates (MSCA mobility rules apply).
📅 Deadline: 18th Dec
🌐 Apply now: www.findaphd.com/phds/project...
🔬 Decoding Early Life Microbiota & Host Interactions
🧬 Ideal for those with bioinformatics/microbiome experience
🌍 Open to international candidates (MSCA mobility rules apply).
📅 Deadline: 18th Dec
🌐 Apply now: www.findaphd.com/phds/project...