Anthony Shiver
@anthonyshiver.bsky.social
Researcher in the life sciences. Expertise in systems biology, biophysics, applied math.
Reposted by Anthony Shiver
Characterizing phage gene essentiality with PhageMaP:
• High-throughput approach to generate genome-wide loss-of-function phage libraries.
• Interrogates gene essentiality w/insights into phage genome organization, host antiviral defense & gene function
www.cell.com/cell-host-mi...
• High-throughput approach to generate genome-wide loss-of-function phage libraries.
• Interrogates gene essentiality w/insights into phage genome organization, host antiviral defense & gene function
www.cell.com/cell-host-mi...
Systematic, high-throughput characterization of bacteriophage gene essentiality on diverse hosts
Chen et al. report PhageMaP, a high-throughput approach to generate and characterize
genome-wide loss-of-function phage libraries. PhageMaP systematically interrogates
conditional gene essentiality, p...
www.cell.com
July 23, 2025 at 12:41 PM
Characterizing phage gene essentiality with PhageMaP:
• High-throughput approach to generate genome-wide loss-of-function phage libraries.
• Interrogates gene essentiality w/insights into phage genome organization, host antiviral defense & gene function
www.cell.com/cell-host-mi...
• High-throughput approach to generate genome-wide loss-of-function phage libraries.
• Interrogates gene essentiality w/insights into phage genome organization, host antiviral defense & gene function
www.cell.com/cell-host-mi...
A future perspective article on the next 10 years in microbial molecular biology and physiology is online now.
journals.asm.org/doi/10.1128/... 🧵👇
journals.asm.org/doi/10.1128/... 🧵👇
An exciting future for microbial molecular biology and physiology | mBio
The first two bacterial genomes were sequenced nearly 30 years ago (1, 2). The cost of one of those sequences, that of Haemophilus influenzae, was over 1,000,000 U.S. dollars and took multiple years (...
journals.asm.org
July 2, 2025 at 10:02 PM
A future perspective article on the next 10 years in microbial molecular biology and physiology is online now.
journals.asm.org/doi/10.1128/... 🧵👇
journals.asm.org/doi/10.1128/... 🧵👇
I reused “Well-Lit” tech from the pandemic, with thanks to Rafael Gómez-Sjöberg, Joana Cabrera, and @andercot.bsky.social.
We had a huge task—picking bacterial stocks from >200 96-well plates and re-arranging them—and the lab's anaerobic liquid handler was broken without the funds to repair. 🧵
We had a huge task—picking bacterial stocks from >200 96-well plates and re-arranging them—and the lab's anaerobic liquid handler was broken without the funds to repair. 🧵
June 18, 2025 at 8:19 PM
I reused “Well-Lit” tech from the pandemic, with thanks to Rafael Gómez-Sjöberg, Joana Cabrera, and @andercot.bsky.social.
We had a huge task—picking bacterial stocks from >200 96-well plates and re-arranging them—and the lab's anaerobic liquid handler was broken without the funds to repair. 🧵
We had a huge task—picking bacterial stocks from >200 96-well plates and re-arranging them—and the lab's anaerobic liquid handler was broken without the funds to repair. 🧵
Berkeley Lab released a news article describing our recent work on the genetics of the infant-specialized bifidobacteria biosciences.lbl.gov/2025/05/01/h...
Barcoded Transposons Help Mine the Secrets of the Human Gut - Biosciences Area
Researchers have demonstrated a high-impact approach for dissecting complex host-microbe interactions in the infant microbiome, revealing new possibilities for studying the broader microbial world.
biosciences.lbl.gov
June 11, 2025 at 7:10 PM
Berkeley Lab released a news article describing our recent work on the genetics of the infant-specialized bifidobacteria biosciences.lbl.gov/2025/05/01/h...
Interested in the influence of the infant microbiome on health? Quickly interrogating non-model organisms using omic approaches?
A new publication, describing genome-scale resources in bifidobacteria, is now available online: doi.org/10.1016/j.ce...
#microbiome #microsky
A new publication, describing genome-scale resources in bifidobacteria, is now available online: doi.org/10.1016/j.ce...
#microbiome #microsky
March 13, 2025 at 10:35 PM
Interested in the influence of the infant microbiome on health? Quickly interrogating non-model organisms using omic approaches?
A new publication, describing genome-scale resources in bifidobacteria, is now available online: doi.org/10.1016/j.ce...
#microbiome #microsky
A new publication, describing genome-scale resources in bifidobacteria, is now available online: doi.org/10.1016/j.ce...
#microbiome #microsky