Jeremy Delahanty
@scienceishard.bsky.social
Science is pretty neato. Second year graduate student in Misha Ahrens’ and Rob Johnson’s labs at HHMI Janelia collecting big brain and behavior data.
Reposted by Jeremy Delahanty
Excited to share our newest project using spatial transcriptomics with novel image analysis approaches to investigate the impact of biological risk factors for Alzheimer's disease (AD) - APOE haplotype, sex, and genomic ancestry - on molecular states in the locus coeruleus (LC 🔵) of the human 🧠.
Got with the times + made a BSky to share our new, large-scale spatial RNAseq study of adult human #locuscoeruleus! Co-1st auth and cryostat wizard @heenadivecha.bsky.social squeezed 85 tissue sections into 43 Visium arrays. (1/8)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Impact of Alzheimer's disease risk factors and local neuromelanin content on the transcriptomic landscape of the human locus coeruleus
The locus coeruleus (LC) is a small noradrenergic nucleus in the dorsal pons that sends projections across the brain regulating sleep, arousal, attention, stress responses, and some forms of cognition...
www.biorxiv.org
October 31, 2025 at 5:24 PM
Excited to share our newest project using spatial transcriptomics with novel image analysis approaches to investigate the impact of biological risk factors for Alzheimer's disease (AD) - APOE haplotype, sex, and genomic ancestry - on molecular states in the locus coeruleus (LC 🔵) of the human 🧠.
Reposted by Jeremy Delahanty
“It’s hard to know if I should close down my existing projects and/or redouble my efforts writing new grant applications,” Joshua Jacobs, associate professor of biomedical engineering at Columbia University, told @thetransmitter.bsky.social.
By Natalia Mesa
www.thetransmitter.org/funding/nih-...
By Natalia Mesa
www.thetransmitter.org/funding/nih-...
NIH awarded 37 percent fewer neuroscience-related grants in 2025 than in past years
But the agency has spent nearly its entire budget for this fiscal year, which ends tomorrow.
www.thetransmitter.org
September 29, 2025 at 9:11 PM
“It’s hard to know if I should close down my existing projects and/or redouble my efforts writing new grant applications,” Joshua Jacobs, associate professor of biomedical engineering at Columbia University, told @thetransmitter.bsky.social.
By Natalia Mesa
www.thetransmitter.org/funding/nih-...
By Natalia Mesa
www.thetransmitter.org/funding/nih-...
Woohoo! Go Ginny!
Can't wait to read this preprint from Misha Ahrens and team. Calcium imaging in larval zebrafish, in every cell in the body! Amazing.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
August 26, 2025 at 3:28 AM
Woohoo! Go Ginny!
Reposted by Jeremy Delahanty
Can't wait to read this preprint from Misha Ahrens and team. Calcium imaging in larval zebrafish, in every cell in the body! Amazing.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
August 22, 2025 at 10:21 PM
Can't wait to read this preprint from Misha Ahrens and team. Calcium imaging in larval zebrafish, in every cell in the body! Amazing.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Jeremy Delahanty
Here's what this means: it's probably unlawful forPOTUS to stop NIH funds from going to medical research, but POTUS can stop that medical research for a lengthy period of time while the Court of Federal Claims hears lawsuits
This, essentially, destroys the capacity for medical research in the US
This, essentially, destroys the capacity for medical research in the US
Splitting 5-4 (with Chief Justice Roberts joining the three Democratic appointees in dissent), #SCOTUS grants *partial* stay to Trump administration in NIH funding case; holds that challenges to grant terminations (but *not* the underlying guidance) need to be filed in the Court of Federal Claims:
www.supremecourt.gov
August 21, 2025 at 9:58 PM
Here's what this means: it's probably unlawful forPOTUS to stop NIH funds from going to medical research, but POTUS can stop that medical research for a lengthy period of time while the Court of Federal Claims hears lawsuits
This, essentially, destroys the capacity for medical research in the US
This, essentially, destroys the capacity for medical research in the US
Reposted by Jeremy Delahanty
The ideological cancellation of $800 million of scientific research grants because they supposedly focused on DEI was just backed by the Supreme Court. This is horrific on so many levels.
Supreme Court allows NIH to stop making nearly $800M in research grants for now
But the court, in its emergency docket order, also left in place by a 5-4 order a lower court ruling that threw out NIH memos that enforced the administration's policies.
www.npr.org
August 21, 2025 at 11:11 PM
The ideological cancellation of $800 million of scientific research grants because they supposedly focused on DEI was just backed by the Supreme Court. This is horrific on so many levels.
Reposted by Jeremy Delahanty
Yes! Sharing neural recordings improves reproducibility and transparency, and reduces the need for new experiments - we should value it. And reuse is really happening: @steinmetzneuro.bsky.social's datasets (highlighted) have over 80k downloads! 🔥 figshare.com/authors/Nick...
July 7, 2025 at 9:04 PM
Yes! Sharing neural recordings improves reproducibility and transparency, and reduces the need for new experiments - we should value it. And reuse is really happening: @steinmetzneuro.bsky.social's datasets (highlighted) have over 80k downloads! 🔥 figshare.com/authors/Nick...
Reposted by Jeremy Delahanty
Reminder that we still have time to fight this! This bill is being crafted & debated in the coming days and weeks. Organize NOW to do outreach and get people in your neighborhood contacting their reps. @standupforscience.bsky.social has resources. Instructions for Postcards-for-Science are here:
July 7, 2025 at 2:06 PM
Reminder that we still have time to fight this! This bill is being crafted & debated in the coming days and weeks. Organize NOW to do outreach and get people in your neighborhood contacting their reps. @standupforscience.bsky.social has resources. Instructions for Postcards-for-Science are here:
Moving my awesome @pugetsystems.com machine with the help of the legendary @aoracingusa.bsky.social Rexy. Gonna be the fastest (and safest) move ever
June 24, 2025 at 7:36 PM
Moving my awesome @pugetsystems.com machine with the help of the legendary @aoracingusa.bsky.social Rexy. Gonna be the fastest (and safest) move ever
Reposted by Jeremy Delahanty
tl;dr — this EO co-opts the language of open science to implement a system of political control wherein presidential appointees are given broad latitude to designate any number of reasonable scientific activities and inferences as scientific misconduct, and to penalize those involved accordingly.
Restoring Gold Standard Science
By the authority vested in me as President by the Constitution and the laws of the United States of America, including section 7301 of title 5, United
www.whitehouse.gov
May 24, 2025 at 9:28 PM
tl;dr — this EO co-opts the language of open science to implement a system of political control wherein presidential appointees are given broad latitude to designate any number of reasonable scientific activities and inferences as scientific misconduct, and to penalize those involved accordingly.
Reposted by Jeremy Delahanty
1. It's Fustilarian Friday and today's drop is the "Restoring Gold Standard Science" executive order.
My read is that this is designed to (1) protect far-fringe figures such as the antvaxxers now heading our health agencies, and (2) kneecap efforts to use scientific evidence in regulatory policy.
My read is that this is designed to (1) protect far-fringe figures such as the antvaxxers now heading our health agencies, and (2) kneecap efforts to use scientific evidence in regulatory policy.
Restoring Gold Standard Science
By the authority vested in me as President by the Constitution and the laws of the United States of America, including section 7301 of title 5, United
www.whitehouse.gov
May 24, 2025 at 5:24 AM
1. It's Fustilarian Friday and today's drop is the "Restoring Gold Standard Science" executive order.
My read is that this is designed to (1) protect far-fringe figures such as the antvaxxers now heading our health agencies, and (2) kneecap efforts to use scientific evidence in regulatory policy.
My read is that this is designed to (1) protect far-fringe figures such as the antvaxxers now heading our health agencies, and (2) kneecap efforts to use scientific evidence in regulatory policy.
Reposted by Jeremy Delahanty
🧪 Federal science funding cuts directly threaten public services. Reduced operations at NOAA, CDC, and EPA mean compromised weather forecasts, disease surveillance, and environmental safeguards.
How cuts to science funding will hurt ordinary Americans
Federal agencies are struggling to predict the weather and monitor disease
www.economist.com
May 22, 2025 at 1:41 PM
🧪 Federal science funding cuts directly threaten public services. Reduced operations at NOAA, CDC, and EPA mean compromised weather forecasts, disease surveillance, and environmental safeguards.
Reposted by Jeremy Delahanty
HHMI has paused consideration for a new round of its Hanna Gray postdoc fellowship
Applicants feel it's the latest step in the academic pipeline contracting 🧪
www.statnews.com/2025/05/19/h...
Applicants feel it's the latest step in the academic pipeline contracting 🧪
www.statnews.com/2025/05/19/h...
Private funder HHMI pauses postdoc fellowship
As HHMI pauses Hanna Gray fellowship applications, opportunities for young scientists shrink further, making them look overseas.
www.statnews.com
May 19, 2025 at 10:05 PM
HHMI has paused consideration for a new round of its Hanna Gray postdoc fellowship
Applicants feel it's the latest step in the academic pipeline contracting 🧪
www.statnews.com/2025/05/19/h...
Applicants feel it's the latest step in the academic pipeline contracting 🧪
www.statnews.com/2025/05/19/h...
Reposted by Jeremy Delahanty
🚨 Over 700 previously undisclosed #NIH grant terminations were released this week, totaling $1.7B and nearly doubling our count of terminations to >1500.
Diversity supplements for research awards are a huge fraction, as well as service awards and training programs.
grant-watch.us/posts/700-ne...
Diversity supplements for research awards are a huge fraction, as well as service awards and training programs.
grant-watch.us/posts/700-ne...
May 20, 2025 at 7:35 PM
🚨 Over 700 previously undisclosed #NIH grant terminations were released this week, totaling $1.7B and nearly doubling our count of terminations to >1500.
Diversity supplements for research awards are a huge fraction, as well as service awards and training programs.
grant-watch.us/posts/700-ne...
Diversity supplements for research awards are a huge fraction, as well as service awards and training programs.
grant-watch.us/posts/700-ne...
I have learned that graphics programming is literally a miracle and I don’t understand how the hell people do this for a living. Just getting displays to refresh at appropriate time points if they aren’t at the same frame rate was so hard man.
May 16, 2025 at 2:47 AM
I have learned that graphics programming is literally a miracle and I don’t understand how the hell people do this for a living. Just getting displays to refresh at appropriate time points if they aren’t at the same frame rate was so hard man.
Reposted by Jeremy Delahanty
NEW: Whistleblower records show that the NIH axed research grants – even after a federal judge blocked the cuts with an injunction.
www.propublica.org/article/trum...
🧵
www.propublica.org/article/trum...
🧵
Trump’s NIH Axed Research Grants Even After a Judge Blocked the Cuts, Internal Records Show
A lawsuit led by the Washington state attorney general offers an unprecedented view of the termination of more than 600 NIH grants, including transgender research grants threatened by Trump’s executiv...
www.propublica.org
May 7, 2025 at 10:11 PM
NEW: Whistleblower records show that the NIH axed research grants – even after a federal judge blocked the cuts with an injunction.
www.propublica.org/article/trum...
🧵
www.propublica.org/article/trum...
🧵
Reposted by Jeremy Delahanty
The bill, which was approved today by the U.S. House of Representatives and heads next to a Senate vote, includes 20 percent less BRAIN Initiative funding than last year.
By @avaskham.bsky.social
www.thetransmitter.org/funding/u-s-...
By @avaskham.bsky.social
www.thetransmitter.org/funding/u-s-...
U.S. BRAIN Initiative set to lose $81 million this year
A government spending bill, approved today by the House of Representatives, allocates 20 percent less funding for the program than last year.
www.thetransmitter.org
March 12, 2025 at 2:02 AM
The bill, which was approved today by the U.S. House of Representatives and heads next to a Senate vote, includes 20 percent less BRAIN Initiative funding than last year.
By @avaskham.bsky.social
www.thetransmitter.org/funding/u-s-...
By @avaskham.bsky.social
www.thetransmitter.org/funding/u-s-...
Reposted by Jeremy Delahanty
It's hard to say this, but science (& research more generally) is just being **stopped** in the US right now. This is just one university, losing nearly a billion dollars in project funding pretty much overnight. That's people's jobs & the research that could save lives.
www.wsj.com/health/healt...
www.wsj.com/health/healt...
March 12, 2025 at 10:52 AM
It's hard to say this, but science (& research more generally) is just being **stopped** in the US right now. This is just one university, losing nearly a billion dollars in project funding pretty much overnight. That's people's jobs & the research that could save lives.
www.wsj.com/health/healt...
www.wsj.com/health/healt...
Reposted by Jeremy Delahanty
"The Trump administration has terminated $800 million in grants to Johns Hopkins University, spurring the nation’s top spender on research and development to plan layoffs and cancel health projects, from breast-feeding support efforts in Baltimore to mosquito-net programs in Mozambique."
Johns Hopkins Plans Staff Layoffs After $800 Million Grant Cuts
Local and international health research efforts are already winding down as the university braces for even more potential cuts.
www.wsj.com
March 12, 2025 at 12:07 AM
"The Trump administration has terminated $800 million in grants to Johns Hopkins University, spurring the nation’s top spender on research and development to plan layoffs and cancel health projects, from breast-feeding support efforts in Baltimore to mosquito-net programs in Mozambique."
Reposted by Jeremy Delahanty
Johns Hopkins University President Ron Daniels is preparing the Baltimore campus for the possibility of major cuts to programs and staff after seismic changes to federal funding at universities announced last month.
Johns Hopkins University president: We have little choice but to reduce some of our work
In a letter to campus, Johns Hopkins University President Ron Daniels appears to brace the campus for cuts.
buff.ly
March 8, 2025 at 2:21 AM
Johns Hopkins University President Ron Daniels is preparing the Baltimore campus for the possibility of major cuts to programs and staff after seismic changes to federal funding at universities announced last month.
Reposted by Jeremy Delahanty
List includes Harvard University, George Washington University, Johns Hopkins University, New York University, Northwestern University, the University of California, Los Angeles; the University of California, Berkeley, the University of Minnesota, and the University of Southern California.
Trump Pulled $400 million From Columbia. Other Schools Could Be Next.
The administration has circulated a list that includes nine other campuses, accusing them of failure to address antisemitism.
www.nytimes.com
March 9, 2025 at 1:00 AM
List includes Harvard University, George Washington University, Johns Hopkins University, New York University, Northwestern University, the University of California, Los Angeles; the University of California, Berkeley, the University of Minnesota, and the University of Southern California.
Reposted by Jeremy Delahanty
Terrific how-to on communicating the value of basic research to the public in @thetransmitter.bsky.social by @tonyzador.bsky.social.
You may be curious. But when you are communicating the value of what you do, it’s not about you. Point to discoveries.
www.thetransmitter.org/outreach/how...
You may be curious. But when you are communicating the value of what you do, it’s not about you. Point to discoveries.
www.thetransmitter.org/outreach/how...
How to communicate the value of curiosity-driven research
The burden of proof is on us, as researchers, to explain why what we do is valuable to society.
www.thetransmitter.org
March 4, 2025 at 9:21 PM
Terrific how-to on communicating the value of basic research to the public in @thetransmitter.bsky.social by @tonyzador.bsky.social.
You may be curious. But when you are communicating the value of what you do, it’s not about you. Point to discoveries.
www.thetransmitter.org/outreach/how...
You may be curious. But when you are communicating the value of what you do, it’s not about you. Point to discoveries.
www.thetransmitter.org/outreach/how...
Reposted by Jeremy Delahanty
Hi New Yorkers! Consider reaching out to Congresswoman Malliotakis, who is introducing legislation to end federal funding of animal research:
malliotakis.house.gov/media/press-...
malliotakis.house.gov/media/press-...
Malliotakis Introduces Legislation to End Federal Animal Testing
(WASHINGTON, D.C.) – Congresswoman Nicole Malliotakis (NY-11) and Rep.
malliotakis.house.gov
February 28, 2025 at 4:17 PM
Hi New Yorkers! Consider reaching out to Congresswoman Malliotakis, who is introducing legislation to end federal funding of animal research:
malliotakis.house.gov/media/press-...
malliotakis.house.gov/media/press-...
Reposted by Jeremy Delahanty
While there's a lot on this that is to be seen—impacts of the chaotic smashing of govt are coming to light in bits and pieces—from my own corner, I would suggest academic associations holding conferences in the US consult with lawyers NOW and offer support/guidance for trans members.
1/2
1/2
www.theguardian.com/us-news/2025...
The end result of this is trans people can't travel to the USA without the risk of being permanently banned from entering the USA on grounds of "gender fraud".
Already know trans folks in high tech fields who will be cancelling plans to give talks in America.
The end result of this is trans people can't travel to the USA without the risk of being permanently banned from entering the USA on grounds of "gender fraud".
Already know trans folks in high tech fields who will be cancelling plans to give talks in America.
US threatens permanent visa bans on trans athletes based on sex markers
Exclusive: State department memo directs officers to bar those deemed to misrepresent birth sex on applications
www.theguardian.com
February 25, 2025 at 8:23 PM
While there's a lot on this that is to be seen—impacts of the chaotic smashing of govt are coming to light in bits and pieces—from my own corner, I would suggest academic associations holding conferences in the US consult with lawyers NOW and offer support/guidance for trans members.
1/2
1/2
Reposted by Jeremy Delahanty
As someone who has spent the last 25 years studying sex differences in brain function and behavior and the last 10 advocating (loudly) for SABV and working to help my colleagues implement the policy into their work, this is utterly heartbreaking.
Great write up at @thetransmitter.bsky.social on the seeming erasure of SABV in the new era of NIH. Gotta say The Transmitter is killing it the last few weeks, first to report on the Federal Register block and now this. Leading the charge! 💪 www.thetransmitter.org/policy/exclu...
Exclusive: NIH appears to archive policy requiring female animals in studies
Such a shift would “put us back in the dark ages in terms of our science,” says neuroscientist Anne Murphy, who helped to formulate the original policy.
www.thetransmitter.org
February 25, 2025 at 3:37 PM
As someone who has spent the last 25 years studying sex differences in brain function and behavior and the last 10 advocating (loudly) for SABV and working to help my colleagues implement the policy into their work, this is utterly heartbreaking.