Bernie Mulvey
@berniejmulvey.bsky.social
Postdoc at Lieber Institute for Brain Development. Brain molecular regul° and gene express° in health, mood disorders, and neurodegen (and sex diffs therein)
Reposted by Bernie Mulvey
Proud to announce our paper ‘Transcriptomic Analysis of the Human Habenula in Schizophrenia’ from @lieberinstitute.bsky.social is the cover article for the November issue of the American Journal of Psychiatry! 🧠 #HabenulaLIBD #snRNAseq #Habenula doi.org/10.1176/appi...
Transcriptomic Analysis of the Human Habenula in Schizophrenia | American Journal of Psychiatry
Objective: The objective of this study was to define the molecular neuroanatomy of the human habenula (Hb) and identify transcriptomic differences between brains of individuals with schizophrenia and ...
doi.org
November 4, 2025 at 9:31 PM
Proud to announce our paper ‘Transcriptomic Analysis of the Human Habenula in Schizophrenia’ from @lieberinstitute.bsky.social is the cover article for the November issue of the American Journal of Psychiatry! 🧠 #HabenulaLIBD #snRNAseq #Habenula doi.org/10.1176/appi...
Reposted by Bernie Mulvey
A large study of developing brains reveals genetic and molecular differences between males and females. The findings may help explain why neurodevelopmental conditions, including autism, occur at different rates in boys and girls.
By @giorgiag-sciwriter.bsky.social
bit.ly/4q9BsVH
By @giorgiag-sciwriter.bsky.social
bit.ly/4q9BsVH
Gene-activity map of developing brain reveals new clues about autism’s sex bias
Boys and girls may be vulnerable to different genetic changes, which could help explain why the condition is more common in boys despite linked variants appearing more often in girls.
bit.ly
October 16, 2025 at 2:30 PM
A large study of developing brains reveals genetic and molecular differences between males and females. The findings may help explain why neurodevelopmental conditions, including autism, occur at different rates in boys and girls.
By @giorgiag-sciwriter.bsky.social
bit.ly/4q9BsVH
By @giorgiag-sciwriter.bsky.social
bit.ly/4q9BsVH
10/8: Any time you see two tissue sections, the other was the preceding or subsequent 10µm of tissue cut from the same donor, because @heenadivecha.bsky.social is a beast! As is the link to the browser with all 85 tissue sections available: samuibrowser.com/from?url=dat...
November 1, 2025 at 12:50 AM
10/8: Any time you see two tissue sections, the other was the preceding or subsequent 10µm of tissue cut from the same donor, because @heenadivecha.bsky.social is a beast! As is the link to the browser with all 85 tissue sections available: samuibrowser.com/from?url=dat...
9/8: The high-res spatial expression browser! Full-resolution of H&E stained tissue sections and the gene expression from them. Great for seeing neuromelanin. (One sample = one tissue section).
Got with the times + made a BSky to share our new, large-scale spatial RNAseq study of adult human #locuscoeruleus! Co-1st auth and cryostat wizard @heenadivecha.bsky.social squeezed 85 tissue sections into 43 Visium arrays. (1/8)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Impact of Alzheimer's disease risk factors and local neuromelanin content on the transcriptomic landscape of the human locus coeruleus
The locus coeruleus (LC) is a small noradrenergic nucleus in the dorsal pons that sends projections across the brain regulating sleep, arousal, attention, stress responses, and some forms of cognition...
www.biorxiv.org
November 1, 2025 at 12:49 AM
9/8: The high-res spatial expression browser! Full-resolution of H&E stained tissue sections and the gene expression from them. Great for seeing neuromelanin. (One sample = one tissue section).
Got with the times + made a BSky to share our new, large-scale spatial RNAseq study of adult human #locuscoeruleus! Co-1st auth and cryostat wizard @heenadivecha.bsky.social squeezed 85 tissue sections into 43 Visium arrays. (1/8)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Impact of Alzheimer's disease risk factors and local neuromelanin content on the transcriptomic landscape of the human locus coeruleus
The locus coeruleus (LC) is a small noradrenergic nucleus in the dorsal pons that sends projections across the brain regulating sleep, arousal, attention, stress responses, and some forms of cognition...
www.biorxiv.org
October 31, 2025 at 3:42 PM
Got with the times + made a BSky to share our new, large-scale spatial RNAseq study of adult human #locuscoeruleus! Co-1st auth and cryostat wizard @heenadivecha.bsky.social squeezed 85 tissue sections into 43 Visium arrays. (1/8)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...