Sara Luzzi
@saraluzzi.bsky.social
Faculty Fellow at Newcastle University, looking at RNA and steroid hormones in cardio-oncology.
She/her.
https://www.ncl.ac.uk/medical-sciences/people/profile/saraluzzi.html
She/her.
https://www.ncl.ac.uk/medical-sciences/people/profile/saraluzzi.html
Pinned
Sara Luzzi
@saraluzzi.bsky.social
· Nov 13
First post on this platform with some exciting news: I'll be starting a position as Faculty Fellow here in Newcastle in January 2025! The lab will be studying #transcription and #RNA processing in #cardiooncology. More updates to come in the next few months so watch this space! 🦋
Don't miss your chance to register and send your abstract!
🚨Transcription and Chromatin UK is back for 2025🚨
We're in Manchester, UK 17th-19th September for the 3rd annual transcription and chromatin conference. Abstract deadline is the 17th July so make sure you register!
www.eventsforce.net/biochemsoc/f...
We're in Manchester, UK 17th-19th September for the 3rd annual transcription and chromatin conference. Abstract deadline is the 17th July so make sure you register!
www.eventsforce.net/biochemsoc/f...
www.eventsforce.net
July 16, 2025 at 4:12 PM
Don't miss your chance to register and send your abstract!
Transcription and Chromatin UK is back! This time in Manchester, 17th-19th September. Send your abstract by 17th July for the opportunity to discuss your work with the UK RNA and epigenetics community, and with leading experts from abroad. Click the link below and spread the word!
Taking place on 17-19 September 2025, Transcription and Chromatin UK will showcase cutting-edge research and is a ‘mustattend’ for anyone within the transcription and epigenetics community🧪. Register now: www.eventsforce.net/biochemsoc/2...
June 28, 2025 at 5:27 PM
Transcription and Chromatin UK is back! This time in Manchester, 17th-19th September. Send your abstract by 17th July for the opportunity to discuss your work with the UK RNA and epigenetics community, and with leading experts from abroad. Click the link below and spread the word!
Reposted by Sara Luzzi
Lisa Russell just wrote an insightful article for #CancerNews from @cancerresearchuk.org where she takes us through the promise of super-enhancer biology and what it means for cancer. Read the whole article here:
news.cancerresearchuk.org/2025/05/21/b...
news.cancerresearchuk.org/2025/05/21/b...
Beyond the genome: Harnessing the power of super-enhancers for blood cancer - Cancer Research UK - Cancer News
The mysteries of the epiregulome need to be tackled head-on if we are to get new precision treatments for blood cancers
news.cancerresearchuk.org
May 22, 2025 at 1:51 PM
Lisa Russell just wrote an insightful article for #CancerNews from @cancerresearchuk.org where she takes us through the promise of super-enhancer biology and what it means for cancer. Read the whole article here:
news.cancerresearchuk.org/2025/05/21/b...
news.cancerresearchuk.org/2025/05/21/b...
Reposted by Sara Luzzi
Transcription and Chromatin UK is back for 2025 in Manchester! Make sure you register your interest to be kept in the loop about registration and abstract submission. www.biochemistry.org/events-and-t...
Transcription and Chromatin UK 2025
Transcription and Chromatin UK brings together the rich transcription and epigenetics community in the UK and leading experts from abroad, and will feature all aspects of transcription and chromatin r...
www.biochemistry.org
April 1, 2025 at 3:22 PM
Transcription and Chromatin UK is back for 2025 in Manchester! Make sure you register your interest to be kept in the loop about registration and abstract submission. www.biochemistry.org/events-and-t...
Excited to be at the #ProstateCancerUK #MakingProgress meeting. Loads of great research being showcased today @prostateukprofs.bsky.social @prostatecanceruk.bsky.social
April 2, 2025 at 10:10 AM
Excited to be at the #ProstateCancerUK #MakingProgress meeting. Loads of great research being showcased today @prostateukprofs.bsky.social @prostatecanceruk.bsky.social
Reposted by Sara Luzzi
**deadline Mar 30th** Passionate about #cryoEM? Interested in #PhD project on allosteric mechanism of a dynamic enzyme implicated in metabolic and neurological disorders? Join @allostericstate.bsky.social and me in NCL on a funded @mosmedcdt.bsky.social studentship.
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
March 17, 2025 at 10:28 AM
**deadline Mar 30th** Passionate about #cryoEM? Interested in #PhD project on allosteric mechanism of a dynamic enzyme implicated in metabolic and neurological disorders? Join @allostericstate.bsky.social and me in NCL on a funded @mosmedcdt.bsky.social studentship.
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Reposted by Sara Luzzi
We have a 4 year PhD position available to study the impact of the RNA exosome on ribosome specialisation! Get in touch if you are interested or just apply. March 31st deadline.
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
The impact of the RNA exosome on ribosome specialisation in different cell types at Newcastle University on FindAPhD.com
PhD Project - The impact of the RNA exosome on ribosome specialisation in different cell types at Newcastle University, listed on FindAPhD.com
www.findaphd.com
March 4, 2025 at 7:16 PM
We have a 4 year PhD position available to study the impact of the RNA exosome on ribosome specialisation! Get in touch if you are interested or just apply. March 31st deadline.
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Our Research Theme has joined the platform! Hit follow for updates on our work. 🧬🧫🧪🔬
The Cells Genes and Molecules Theme @newcastleuni.bsky.social is very pleased to have joined Bluesky 🙂
March 1, 2025 at 11:04 AM
Our Research Theme has joined the platform! Hit follow for updates on our work. 🧬🧫🧪🔬
Reposted by Sara Luzzi
First: I apologize for never coming here and now doing so only to brag 😬
Second: I am very proud of the people in our lab. We are a small group in a Bio department and this work took an enormous amount of effort from every one here.
rdcu.be/eaxEz
Second: I am very proud of the people in our lab. We are a small group in a Bio department and this work took an enormous amount of effort from every one here.
rdcu.be/eaxEz
Cooperative nutrient scavenging is an evolutionary advantage in cancer
Nature - Nutrient-starved tumour cells cooperate by secreting aminopeptidases that digest oligopeptides in the microenvironment, creating a shared pool of free amino acids.
rdcu.be
February 20, 2025 at 4:39 PM
First: I apologize for never coming here and now doing so only to brag 😬
Second: I am very proud of the people in our lab. We are a small group in a Bio department and this work took an enormous amount of effort from every one here.
rdcu.be/eaxEz
Second: I am very proud of the people in our lab. We are a small group in a Bio department and this work took an enormous amount of effort from every one here.
rdcu.be/eaxEz
Reposted by Sara Luzzi
Today is International Day of Women & Girls in Science.
Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM
Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM
February 11, 2025 at 7:52 AM
Today is International Day of Women & Girls in Science.
Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM
Marie Curie, the first woman to win a Nobel Prize. Her contributions have left an indelible mark on the world of science & health & continue to inspire generations of scientists & innovators. 🔬 #WomenInScience #WomenInSTEM
Reposted by Sara Luzzi
Proteogenomic analysis of evolved aneuploid cell lines & primary tumors reveals cancer adaptive strategies for alleviating aneuploidy consequences – including increased expression of DNA replication & repair factors & of FOXM1 targets
Zuzana Storchova and coworkers
www.embopress.org/doi/full/10....
Zuzana Storchova and coworkers
www.embopress.org/doi/full/10....
February 10, 2025 at 12:08 PM
Proteogenomic analysis of evolved aneuploid cell lines & primary tumors reveals cancer adaptive strategies for alleviating aneuploidy consequences – including increased expression of DNA replication & repair factors & of FOXM1 targets
Zuzana Storchova and coworkers
www.embopress.org/doi/full/10....
Zuzana Storchova and coworkers
www.embopress.org/doi/full/10....
Reposted by Sara Luzzi
🚨Thanks to generous support from @cancerresearchuk.org, we have multiple postdoctoral positions available in our lab (www.mardakhehlab.info) @oxfordbiochemistry.bsky.social to study ribosomes synthesis in cancer. Get in touch if you’re interested + RT and spread the word! 📣 #cancer #RNA 🚨
February 5, 2025 at 12:02 AM
🚨Thanks to generous support from @cancerresearchuk.org, we have multiple postdoctoral positions available in our lab (www.mardakhehlab.info) @oxfordbiochemistry.bsky.social to study ribosomes synthesis in cancer. Get in touch if you’re interested + RT and spread the word! 📣 #cancer #RNA 🚨
Reposted by Sara Luzzi
Here is a growing list of conferences and schools in gene regulation for 2025 generegulation.org/conferences-.... You can order/filter this list by the date, deadline, location. Please reply here to suggest new events*
*should be specific to gene regulation
*should be specific to gene regulation
Conferences & Schools – 2025 – Gene Regulation – Teif Lab
generegulation.org
January 14, 2025 at 7:14 PM
Here is a growing list of conferences and schools in gene regulation for 2025 generegulation.org/conferences-.... You can order/filter this list by the date, deadline, location. Please reply here to suggest new events*
*should be specific to gene regulation
*should be specific to gene regulation
Reposted by Sara Luzzi
PhD Position available in my lab. Interested in prostate cancer research and developing novel disease models to accelerate research impact then this is for you. Come and join of research community @nucancer.bsky.social
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
PhD studentship in Prostate Cancer - Refining human prostate tissue culture techniques for better in vivo mimicry and therapeutic insights at Newcastle University on FindAPhD.com
PhD Project - PhD studentship in Prostate Cancer - Refining human prostate tissue culture techniques for better in vivo mimicry and therapeutic insights at Newcastle University, listed on FindAPhD.com
www.findaphd.com
January 30, 2025 at 4:26 PM
PhD Position available in my lab. Interested in prostate cancer research and developing novel disease models to accelerate research impact then this is for you. Come and join of research community @nucancer.bsky.social
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Reposted by Sara Luzzi
Do you know where transcription of a gene actually stops? Hint: it is not the annotated gene end.
In our new paper in Nucleic Acids Research we argue that phosphorylation on threonine 4 of RNA Pol II CTD is a marker of transcription termination in animals... 🧵
academic.oup.com/nar/advance-...
In our new paper in Nucleic Acids Research we argue that phosphorylation on threonine 4 of RNA Pol II CTD is a marker of transcription termination in animals... 🧵
academic.oup.com/nar/advance-...
December 27, 2024 at 4:01 PM
Do you know where transcription of a gene actually stops? Hint: it is not the annotated gene end.
In our new paper in Nucleic Acids Research we argue that phosphorylation on threonine 4 of RNA Pol II CTD is a marker of transcription termination in animals... 🧵
academic.oup.com/nar/advance-...
In our new paper in Nucleic Acids Research we argue that phosphorylation on threonine 4 of RNA Pol II CTD is a marker of transcription termination in animals... 🧵
academic.oup.com/nar/advance-...
Reposted by Sara Luzzi
We just posted a preprint about a death mechanism that we find truly surprising.
When you turn off transcription, cells die (duh!)... but did you know this happens due to loss of Pol II itself, not loss of Pol II activity!?!
preprint here and a thread (1/n): www.biorxiv.org/content/10.1...
🧪
When you turn off transcription, cells die (duh!)... but did you know this happens due to loss of Pol II itself, not loss of Pol II activity!?!
preprint here and a thread (1/n): www.biorxiv.org/content/10.1...
🧪
Pol II degradation activates cell death independently from the loss of transcription
Pol II-mediated transcription is essential for eukaryotic life. While loss of transcription is thought to be universally lethal, the associated mechanisms promoting cell death are not yet known. Here,...
www.biorxiv.org
December 13, 2024 at 2:17 PM
We just posted a preprint about a death mechanism that we find truly surprising.
When you turn off transcription, cells die (duh!)... but did you know this happens due to loss of Pol II itself, not loss of Pol II activity!?!
preprint here and a thread (1/n): www.biorxiv.org/content/10.1...
🧪
When you turn off transcription, cells die (duh!)... but did you know this happens due to loss of Pol II itself, not loss of Pol II activity!?!
preprint here and a thread (1/n): www.biorxiv.org/content/10.1...
🧪
Reposted by Sara Luzzi
Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of @jonmarkert.bsky.social!
tinyurl.com/setd2
tinyurl.com/setd2
December 12, 2024 at 7:16 PM
Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of @jonmarkert.bsky.social!
tinyurl.com/setd2
tinyurl.com/setd2
Reposted by Sara Luzzi
Beware using FLAG tags in SUMOylation studies, as the lysines in the DYKDDDDK sequence can be SUMOylated according to this report... www.sciencedirect.com/science/arti...
An Atypical Mechanism of SUMOylation of Neurofibromin SecPH Domain Provides New Insights into SUMOylation Site Selection
Neurofibromin (Nf1) is a giant multidomain protein encoded by the tumour-suppressor gene NF1. NF1 is mutated in a common genetic disease, neurofibroma…
www.sciencedirect.com
November 19, 2024 at 2:12 PM
Beware using FLAG tags in SUMOylation studies, as the lysines in the DYKDDDDK sequence can be SUMOylated according to this report... www.sciencedirect.com/science/arti...
Interested in RNA biology, cancer or vascular research? I have a position open for either a research assistant or a new postdoc to start expanding the fast-growing research area of cardio-oncology! Apply here: jobs.ncl.ac.uk/job/Newcastl...
Happy to have informal chats! Please share 🧬.
Happy to have informal chats! Please share 🧬.
Research Assistant/Associate - Regulation of gene expression
Research Assistant/Associate - Regulation of gene expression
jobs.ncl.ac.uk
December 3, 2024 at 4:21 PM
Interested in RNA biology, cancer or vascular research? I have a position open for either a research assistant or a new postdoc to start expanding the fast-growing research area of cardio-oncology! Apply here: jobs.ncl.ac.uk/job/Newcastl...
Happy to have informal chats! Please share 🧬.
Happy to have informal chats! Please share 🧬.
Reposted by Sara Luzzi
Are you looking for PhD studentship? We're advertising a fully funded PhD project, get in touch if you're interested.
The project focuses the effects of hypoxia in tumours on the oestrogen response in breast cancer.
Details: www.findaphd.com/phds/project...
#PhDLife #BCMS 🧪 Please Share.
The project focuses the effects of hypoxia in tumours on the oestrogen response in breast cancer.
Details: www.findaphd.com/phds/project...
#PhDLife #BCMS 🧪 Please Share.
Elucidating the Mechanism of Hypoxic Reprogramming of the Estrogen Response. at University of York on FindAPhD.com
PhD Project - Elucidating the Mechanism of Hypoxic Reprogramming of the Estrogen Response. at University of York, listed on FindAPhD.com
www.findaphd.com
November 24, 2024 at 1:38 PM
Are you looking for PhD studentship? We're advertising a fully funded PhD project, get in touch if you're interested.
The project focuses the effects of hypoxia in tumours on the oestrogen response in breast cancer.
Details: www.findaphd.com/phds/project...
#PhDLife #BCMS 🧪 Please Share.
The project focuses the effects of hypoxia in tumours on the oestrogen response in breast cancer.
Details: www.findaphd.com/phds/project...
#PhDLife #BCMS 🧪 Please Share.
Reposted by Sara Luzzi
First post on Bluesky! I have been awarded a @thebhf.bsky.social 3 year #PhD Studentship so looking for enthusiastic people to apply who are interested in researching the #genetics of #cardiovascular development @newcastleuni.bsky.social. Apply here: tinyurl.com/yc6paa5w
Search for Postgraduate Scholarships and Other Funding
We know that how you fund your postgraduate studies is very important. Our funding database gets you to the information you need quickly.
tinyurl.com
November 22, 2024 at 1:55 PM
First post on Bluesky! I have been awarded a @thebhf.bsky.social 3 year #PhD Studentship so looking for enthusiastic people to apply who are interested in researching the #genetics of #cardiovascular development @newcastleuni.bsky.social. Apply here: tinyurl.com/yc6paa5w
Reposted by Sara Luzzi
If you're here to reconnect with Nuclear Receptor biologists, I made a go at a starter pack of who I've found.
If you want to be added or if you have suggestions of wonderful people I've missed - let me know.
You're also welcome to follow me for StarTrek gifs and scicomm.
🧪
go.bsky.app/UeBP3kx
If you want to be added or if you have suggestions of wonderful people I've missed - let me know.
You're also welcome to follow me for StarTrek gifs and scicomm.
🧪
go.bsky.app/UeBP3kx
November 19, 2024 at 5:32 PM
If you're here to reconnect with Nuclear Receptor biologists, I made a go at a starter pack of who I've found.
If you want to be added or if you have suggestions of wonderful people I've missed - let me know.
You're also welcome to follow me for StarTrek gifs and scicomm.
🧪
go.bsky.app/UeBP3kx
If you want to be added or if you have suggestions of wonderful people I've missed - let me know.
You're also welcome to follow me for StarTrek gifs and scicomm.
🧪
go.bsky.app/UeBP3kx
Reposted by Sara Luzzi
#RNA researchers and afficionados: New to Bluesky or been here for a while?
Check my #RNAsky starting pack and feel free to ask me to add you to the list. Or share with us your RNA starter pack ! 🧪
go.bsky.app/RN6HnZp
Check my #RNAsky starting pack and feel free to ask me to add you to the list. Or share with us your RNA starter pack ! 🧪
go.bsky.app/RN6HnZp
November 10, 2024 at 11:48 AM
#RNA researchers and afficionados: New to Bluesky or been here for a while?
Check my #RNAsky starting pack and feel free to ask me to add you to the list. Or share with us your RNA starter pack ! 🧪
go.bsky.app/RN6HnZp
Check my #RNAsky starting pack and feel free to ask me to add you to the list. Or share with us your RNA starter pack ! 🧪
go.bsky.app/RN6HnZp
First post on this platform with some exciting news: I'll be starting a position as Faculty Fellow here in Newcastle in January 2025! The lab will be studying #transcription and #RNA processing in #cardiooncology. More updates to come in the next few months so watch this space! 🦋
November 13, 2024 at 5:01 PM
First post on this platform with some exciting news: I'll be starting a position as Faculty Fellow here in Newcastle in January 2025! The lab will be studying #transcription and #RNA processing in #cardiooncology. More updates to come in the next few months so watch this space! 🦋