Bruno Rodrigues
@rodriguesbruno.bsky.social
Scientist and PhD candidate at @ufrjoficial.bsky.social.
Interested in how different organisms work.
Interested in how different organisms work.
Pinned
O-GlcNAcylation regulates tyrosine hydroxylase serine 40 phosphorylation and L-DOPA levels | American Journal of Physiology-Cell Physiology
O-GlcNAcylation is a post-translational modification characterized by the covalent attachment of a single moiety of GlcNAc on serine/threonine residues in proteins. Tyrosine hydroxylase (TH), the rate...
journals.physiology.org
🚨New paper alert!🚨I'm excited to share the key findings of our latest research. It focuses on a fascinating molecular connection between sugar metabolism and neurotransmitter synthesis, by revealing how O-GlcNAcylation regulates tyrosine hydroxylase. journals.physiology.org/doi/abs/10.1...
Reposted by Bruno Rodrigues
I am looking for postdocs to join my group at NIH. Are you interested in Development, Evolution, Genetics, Genomics, and Human health? Please apply! www.training.nih.gov/jobs/pdf-mb-...
www.training.nih.gov
April 29, 2025 at 2:59 PM
I am looking for postdocs to join my group at NIH. Are you interested in Development, Evolution, Genetics, Genomics, and Human health? Please apply! www.training.nih.gov/jobs/pdf-mb-...
Reposted by Bruno Rodrigues
It's #MicroscopyMonday, so let's take a peek into the 🔬
This movie was taken by Shinya Inuoe, who built the polarizing microscope that allowed scientists to see mitotic spindle fibers live for the first time.
Dr. Inuoe premiered his research at MBL.
This movie was taken by Shinya Inuoe, who built the polarizing microscope that allowed scientists to see mitotic spindle fibers live for the first time.
Dr. Inuoe premiered his research at MBL.
May 5, 2025 at 8:53 PM
It's #MicroscopyMonday, so let's take a peek into the 🔬
This movie was taken by Shinya Inuoe, who built the polarizing microscope that allowed scientists to see mitotic spindle fibers live for the first time.
Dr. Inuoe premiered his research at MBL.
This movie was taken by Shinya Inuoe, who built the polarizing microscope that allowed scientists to see mitotic spindle fibers live for the first time.
Dr. Inuoe premiered his research at MBL.
Reposted by Bruno Rodrigues
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
April 10, 2025 at 6:06 AM
If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social
Reposted by Bruno Rodrigues
🚨 JOB OFFER in our lab at Institut Pasteur 🚨
We are looking for a postdoc! Please repost 🙏
We are looking for a postdoc! Please repost 🙏
April 7, 2025 at 7:16 AM
🚨 JOB OFFER in our lab at Institut Pasteur 🚨
We are looking for a postdoc! Please repost 🙏
We are looking for a postdoc! Please repost 🙏
Reposted by Bruno Rodrigues
A new benchmarking study assesses methods for comparing chromatin contact maps in 3D genome research.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
March 19, 2025 at 3:37 PM
A new benchmarking study assesses methods for comparing chromatin contact maps in 3D genome research.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Bruno Rodrigues
🎙️ASBMB's new series features interviews with biological and life sciences professionals about their careers!
ow.ly/268250UYcmx
🎧Check out episode 1: A conversation w/Tom Kiselak (Thermo Fisher Scientific), who holds a #PhD in analytical chemistry & works as a patent attorney: youtu.be/enBtSSTQT9A.
ow.ly/268250UYcmx
🎧Check out episode 1: A conversation w/Tom Kiselak (Thermo Fisher Scientific), who holds a #PhD in analytical chemistry & works as a patent attorney: youtu.be/enBtSSTQT9A.
In conversation with... Tom Kiselak
YouTube video by American Society for Biochemistry and Molecular Biology (ASBMB)
youtu.be
February 12, 2025 at 1:36 AM
🎙️ASBMB's new series features interviews with biological and life sciences professionals about their careers!
ow.ly/268250UYcmx
🎧Check out episode 1: A conversation w/Tom Kiselak (Thermo Fisher Scientific), who holds a #PhD in analytical chemistry & works as a patent attorney: youtu.be/enBtSSTQT9A.
ow.ly/268250UYcmx
🎧Check out episode 1: A conversation w/Tom Kiselak (Thermo Fisher Scientific), who holds a #PhD in analytical chemistry & works as a patent attorney: youtu.be/enBtSSTQT9A.
Reposted by Bruno Rodrigues
Government isn't a business. The goal isn't to save money. Success isn't measured by budget surplus.
The goal is to spend money, investing in society. Every dollar spent on education, healthcare, and science is an investment in our collective wellbeing.
The goal is to spend money, investing in society. Every dollar spent on education, healthcare, and science is an investment in our collective wellbeing.
February 8, 2025 at 11:23 PM
Government isn't a business. The goal isn't to save money. Success isn't measured by budget surplus.
The goal is to spend money, investing in society. Every dollar spent on education, healthcare, and science is an investment in our collective wellbeing.
The goal is to spend money, investing in society. Every dollar spent on education, healthcare, and science is an investment in our collective wellbeing.
Reposted by Bruno Rodrigues
Our latest work: how can compartmentalization emerge in a eukaryotic genome lacking canonical heterochromatin?
By investigating bacterial genomes put in yeast, we show that the presence or absence of transcription is sufficient!
#chromatin #3Dgenome #generegulation
www.science.org/doi/10.1126/...
👇
By investigating bacterial genomes put in yeast, we show that the presence or absence of transcription is sufficient!
#chromatin #3Dgenome #generegulation
www.science.org/doi/10.1126/...
👇
Sequence-dependent activity and compartmentalization of foreign DNA in a eukaryotic nucleus
In eukaryotes, DNA-associated protein complexes coevolve with genomic sequences to orchestrate chromatin folding. We investigate the relationship between DNA sequence and the spontaneous loading and a...
www.science.org
February 7, 2025 at 10:22 AM
Our latest work: how can compartmentalization emerge in a eukaryotic genome lacking canonical heterochromatin?
By investigating bacterial genomes put in yeast, we show that the presence or absence of transcription is sufficient!
#chromatin #3Dgenome #generegulation
www.science.org/doi/10.1126/...
👇
By investigating bacterial genomes put in yeast, we show that the presence or absence of transcription is sufficient!
#chromatin #3Dgenome #generegulation
www.science.org/doi/10.1126/...
👇
🚨New paper alert!🚨I'm excited to share the key findings of our latest research. It focuses on a fascinating molecular connection between sugar metabolism and neurotransmitter synthesis, by revealing how O-GlcNAcylation regulates tyrosine hydroxylase. journals.physiology.org/doi/abs/10.1...
O-GlcNAcylation regulates tyrosine hydroxylase serine 40 phosphorylation and L-DOPA levels | American Journal of Physiology-Cell Physiology
O-GlcNAcylation is a post-translational modification characterized by the covalent attachment of a single moiety of GlcNAc on serine/threonine residues in proteins. Tyrosine hydroxylase (TH), the rate...
journals.physiology.org
February 1, 2025 at 3:54 PM
🚨New paper alert!🚨I'm excited to share the key findings of our latest research. It focuses on a fascinating molecular connection between sugar metabolism and neurotransmitter synthesis, by revealing how O-GlcNAcylation regulates tyrosine hydroxylase. journals.physiology.org/doi/abs/10.1...
Reposted by Bruno Rodrigues
The ASBMB "O-GlcNAc 🟦 in Health and Disease" conference is coming to Duke University, July 11-13, 2025! Thrilled to co-chair with Mike Boyce 🙌
Confirmed speakers in comments👇
Can’t wait to see you there! 🙌
asbmb.org/meetings-eve...
#glycotime #ASBMB
Confirmed speakers in comments👇
Can’t wait to see you there! 🙌
asbmb.org/meetings-eve...
#glycotime #ASBMB
O-GlcNAcylation in health and disease
July 10–13, 2025 | Durham, N.C.
asbmb.org
January 6, 2025 at 6:41 PM
The ASBMB "O-GlcNAc 🟦 in Health and Disease" conference is coming to Duke University, July 11-13, 2025! Thrilled to co-chair with Mike Boyce 🙌
Confirmed speakers in comments👇
Can’t wait to see you there! 🙌
asbmb.org/meetings-eve...
#glycotime #ASBMB
Confirmed speakers in comments👇
Can’t wait to see you there! 🙌
asbmb.org/meetings-eve...
#glycotime #ASBMB
Reposted by Bruno Rodrigues
The geometric basis of epithelial convergent extension.
https://elifesciences.org/articles/95521?utm_source=bluesky&utm_medium=social&utm_campaign=organic
https://elifesciences.org/articles/95521?utm_source=bluesky&utm_medium=social&utm_campaign=organic
January 4, 2025 at 9:01 PM
The geometric basis of epithelial convergent extension.
https://elifesciences.org/articles/95521?utm_source=bluesky&utm_medium=social&utm_campaign=organic
https://elifesciences.org/articles/95521?utm_source=bluesky&utm_medium=social&utm_campaign=organic
Reposted by Bruno Rodrigues
Our lab has multiple open positions for post-docs to study the regulation and function of cytoplasm mechanics during embryo development.
Details below 👇👇
Please Repost !!!
@ijmonod.bsky.social @cnrs.bsky.social
Details below 👇👇
Please Repost !!!
@ijmonod.bsky.social @cnrs.bsky.social
January 3, 2025 at 3:33 PM
Our lab has multiple open positions for post-docs to study the regulation and function of cytoplasm mechanics during embryo development.
Details below 👇👇
Please Repost !!!
@ijmonod.bsky.social @cnrs.bsky.social
Details below 👇👇
Please Repost !!!
@ijmonod.bsky.social @cnrs.bsky.social
Reposted by Bruno Rodrigues
The Institut Pasteur is recruiting group leaders!
Pasteur is an absolute incredible environment to start your lab. Surrounded by so many great scientists, in the beautiful city of Paris.
Come eat 🥐 and conduct awesome science.
Contact me if you want info !
research.pasteur.fr/en/call/call...
Pasteur is an absolute incredible environment to start your lab. Surrounded by so many great scientists, in the beautiful city of Paris.
Come eat 🥐 and conduct awesome science.
Contact me if you want info !
research.pasteur.fr/en/call/call...
Call for applications 2025 – Creation of new research groups at the Institut Pasteur | Research - Institut Pasteur
research.pasteur.fr
December 16, 2024 at 10:07 AM
The Institut Pasteur is recruiting group leaders!
Pasteur is an absolute incredible environment to start your lab. Surrounded by so many great scientists, in the beautiful city of Paris.
Come eat 🥐 and conduct awesome science.
Contact me if you want info !
research.pasteur.fr/en/call/call...
Pasteur is an absolute incredible environment to start your lab. Surrounded by so many great scientists, in the beautiful city of Paris.
Come eat 🥐 and conduct awesome science.
Contact me if you want info !
research.pasteur.fr/en/call/call...
Reposted by Bruno Rodrigues
📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...
December 16, 2024 at 11:50 AM
📣 Please share: We’re hiring a tenure-track Group Leader in Multicellular Systems to explore the molecular and cellular mechanisms driving the formation, maintenance, or destabilization of tissues, organs and organisms. Apply at: www.fmi.ch/education-ca...
Reposted by Bruno Rodrigues
Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of @jonmarkert.bsky.social!
tinyurl.com/setd2
tinyurl.com/setd2
December 12, 2024 at 7:16 PM
Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of @jonmarkert.bsky.social!
tinyurl.com/setd2
tinyurl.com/setd2
Reposted by Bruno Rodrigues
The birth of fruit fly's central nervous system imaged with multicolor #adaptive #lightsheet microscopy. The microscope self-aligns to a signal that appears during imaging.
www.nature.com/articles/nbt...
www.nature.com/articles/nbt...
December 11, 2024 at 8:32 PM
The birth of fruit fly's central nervous system imaged with multicolor #adaptive #lightsheet microscopy. The microscope self-aligns to a signal that appears during imaging.
www.nature.com/articles/nbt...
www.nature.com/articles/nbt...
Reposted by Bruno Rodrigues
The curious case of the comb jelly | Science Sessions | PNAS www.pnas.org/post/podcast...
Listen to our podcast where we describe a #ctenophore with the ability to reverse its development to an earlier stage of life.
@joanjsoto.bsky.social @msarscentre.bsky.social @pnas.org #rejuvenation
Listen to our podcast where we describe a #ctenophore with the ability to reverse its development to an earlier stage of life.
@joanjsoto.bsky.social @msarscentre.bsky.social @pnas.org #rejuvenation
The curious case of the comb jelly
Joan Soto-Angel and Pawel Burkhardt describe a comb jelly with the ability to reverse its development to an earlier stage of life.
www.pnas.org
December 11, 2024 at 12:28 PM
The curious case of the comb jelly | Science Sessions | PNAS www.pnas.org/post/podcast...
Listen to our podcast where we describe a #ctenophore with the ability to reverse its development to an earlier stage of life.
@joanjsoto.bsky.social @msarscentre.bsky.social @pnas.org #rejuvenation
Listen to our podcast where we describe a #ctenophore with the ability to reverse its development to an earlier stage of life.
@joanjsoto.bsky.social @msarscentre.bsky.social @pnas.org #rejuvenation
Reposted by Bruno Rodrigues
Liver metabolizes high fructose corn syrup to fructose, which leads to increase production of LPC lipids that promote tumor growth.
#Glycotime
www.nature.com/articles/s41...
#Glycotime
www.nature.com/articles/s41...
Dietary fructose enhances tumour growth indirectly via interorgan lipid transfer - Nature
Dietary fructose enhances tumour growth in animal models of melanoma, breast cancer and cervical cancer indirectly via metabolite transfer.
www.nature.com
December 11, 2024 at 8:42 AM
Liver metabolizes high fructose corn syrup to fructose, which leads to increase production of LPC lipids that promote tumor growth.
#Glycotime
www.nature.com/articles/s41...
#Glycotime
www.nature.com/articles/s41...
Reposted by Bruno Rodrigues
Fruit fly female’s seminal receptacle with GFP tagged sperm swimming
December 7, 2024 at 7:04 AM
Fruit fly female’s seminal receptacle with GFP tagged sperm swimming
Reposted by Bruno Rodrigues
🦑 The vampire squid (Vampyroteuthis infernalis) isn’t a true squid—it’s a living fossil combining squid and octopus traits! It thrives in the oxygen-depleted "midnight zone." #MolluscMonday
December 9, 2024 at 3:12 PM
🦑 The vampire squid (Vampyroteuthis infernalis) isn’t a true squid—it’s a living fossil combining squid and octopus traits! It thrives in the oxygen-depleted "midnight zone." #MolluscMonday
Reposted by Bruno Rodrigues
For the dev bio crowd : there is a call for junior group leader at Institut Pasteur in Paris and one of the axis covered is related to development. Come and join us in this exciting place and become one of our colleague @devstempasteur.bsky.social
Please RT !!
research.pasteur.fr/fr/call/call...
Please RT !!
research.pasteur.fr/fr/call/call...
Call for applications 2025 – Creation of new research groups at the Institut Pasteur | Research - Institut Pasteur
research.pasteur.fr
December 8, 2024 at 9:54 PM
For the dev bio crowd : there is a call for junior group leader at Institut Pasteur in Paris and one of the axis covered is related to development. Come and join us in this exciting place and become one of our colleague @devstempasteur.bsky.social
Please RT !!
research.pasteur.fr/fr/call/call...
Please RT !!
research.pasteur.fr/fr/call/call...
Reposted by Bruno Rodrigues
Continuing to go through my trove of cool videos... here is a classic from my work with Philipp Keller's team at @hhmijanelia.bsky.social
A developing fly embryo imaged with a SiMView #lightsheet microscope augmented with our Autopilot self-alignment system.
www.nature.com/articles/nbt...
🧪🔬🪰💻
A developing fly embryo imaged with a SiMView #lightsheet microscope augmented with our Autopilot self-alignment system.
www.nature.com/articles/nbt...
🧪🔬🪰💻
December 9, 2024 at 5:25 PM
Continuing to go through my trove of cool videos... here is a classic from my work with Philipp Keller's team at @hhmijanelia.bsky.social
A developing fly embryo imaged with a SiMView #lightsheet microscope augmented with our Autopilot self-alignment system.
www.nature.com/articles/nbt...
🧪🔬🪰💻
A developing fly embryo imaged with a SiMView #lightsheet microscope augmented with our Autopilot self-alignment system.
www.nature.com/articles/nbt...
🧪🔬🪰💻
Reposted by Bruno Rodrigues
Check out this new work from Rhiju Das and coworkers @stanfordmedicine.bsky.social, large ornate RNAs form homooligomeric stable complexes, not so different from proteins after all
Naturally ornate RNA-only complexes revealed by cryo-EM https://www.biorxiv.org/content/10.1101/2024.12.08.627333v1
December 9, 2024 at 6:03 PM
Check out this new work from Rhiju Das and coworkers @stanfordmedicine.bsky.social, large ornate RNAs form homooligomeric stable complexes, not so different from proteins after all
Reposted by Bruno Rodrigues
How cool is that! Thank you to @demishassabis.bsky.social and John Jumper for highlighting our #AlphaFold use to gain molecular insights into the mechanism of fertilization in interviews and even your #NobelLecture! Interested in reading more? Check out our paper! www.cell.com/cell/fulltex...
December 9, 2024 at 3:53 PM
How cool is that! Thank you to @demishassabis.bsky.social and John Jumper for highlighting our #AlphaFold use to gain molecular insights into the mechanism of fertilization in interviews and even your #NobelLecture! Interested in reading more? Check out our paper! www.cell.com/cell/fulltex...