Renu Dhanasekaran
@renumathyd.bsky.social
Physician scientist at Stanford University
Passionate about liver cancer research
Transplant Hepatologist
Co-Founder Arithmedics
Passionate about liver cancer research
Transplant Hepatologist
Co-Founder Arithmedics
Reposted by Renu Dhanasekaran
The current administration’s narrative that Harvard (and all universities) feel “entitled” to federal dollars misleads the public. Nor are these funds a “privilege” 1/n
Harvard may have a lot of issues, but none of the accusations in this acid-tripping letter are it. Don't know whether to laugh or cry as I watch monkeys tear up pearl strings.
🚨🚨 Deranged letter from Education Secretary Linda McMahon to Harvard’s president, cutting off federal funding for any new grants.
Worth reading in full. It is NUTS.
Worth reading in full. It is NUTS.
May 6, 2025 at 1:31 AM
The current administration’s narrative that Harvard (and all universities) feel “entitled” to federal dollars misleads the public. Nor are these funds a “privilege” 1/n
Reposted by Renu Dhanasekaran
Introducing our single-cell DVP framework combining strategic cell selection with protein gradient mapping algorithms. Analyzing hepatocyte proteomes across 18 human livers, revealing cross-species differences, and mapping disruptions in liver fibrosis.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
April 14, 2025 at 9:29 AM
Introducing our single-cell DVP framework combining strategic cell selection with protein gradient mapping algorithms. Analyzing hepatocyte proteomes across 18 human livers, revealing cross-species differences, and mapping disruptions in liver fibrosis.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Renu Dhanasekaran
A practical review of new AGA guidance on PVT management by @drjessicadavis.bsky.social
#liversky
📍don’t delay AC
📍can hold AC for EGD for 48 hours
📍AC does NOT increase risk of bleeding from varices while you wait for EGD
#liversky
📍don’t delay AC
📍can hold AC for EGD for 48 hours
📍AC does NOT increase risk of bleeding from varices while you wait for EGD
April 5, 2025 at 2:00 PM
A practical review of new AGA guidance on PVT management by @drjessicadavis.bsky.social
#liversky
📍don’t delay AC
📍can hold AC for EGD for 48 hours
📍AC does NOT increase risk of bleeding from varices while you wait for EGD
#liversky
📍don’t delay AC
📍can hold AC for EGD for 48 hours
📍AC does NOT increase risk of bleeding from varices while you wait for EGD
Reposted by Renu Dhanasekaran
The first ever @fda.gov approved treatment for IgG4-RD is upon us. #inebilizumab #uplizna @amgen.bsky.social
A much needed option for this very heterogenous and challenging disease which can literally affect any organ but prominently liver and bile ducts.
#liversky #gisky
A much needed option for this very heterogenous and challenging disease which can literally affect any organ but prominently liver and bile ducts.
#liversky #gisky
April 4, 2025 at 2:17 PM
The first ever @fda.gov approved treatment for IgG4-RD is upon us. #inebilizumab #uplizna @amgen.bsky.social
A much needed option for this very heterogenous and challenging disease which can literally affect any organ but prominently liver and bile ducts.
#liversky #gisky
A much needed option for this very heterogenous and challenging disease which can literally affect any organ but prominently liver and bile ducts.
#liversky #gisky
Reposted by Renu Dhanasekaran
Congrats to Thailand for nearly eliminating vertical transmission of hepatitis B
The vaccine works
doi.org/10.12932/ap-...
The vaccine works
doi.org/10.12932/ap-...
March 31, 2025 at 12:13 AM
Congrats to Thailand for nearly eliminating vertical transmission of hepatitis B
The vaccine works
doi.org/10.12932/ap-...
The vaccine works
doi.org/10.12932/ap-...
Reposted by Renu Dhanasekaran
Online now: A spatially resolved transcriptome landscape during thyroid cancer progression Online now:
A spatially resolved transcriptome landscape during thyroid cancer progression
Liao et al. integrate spatial transcriptomics and scRNA-seq to map thyroid cancer progression. They identify distinct thyrocyte subpopulations and tumor-stage-specific cell-cell interactions, highlighting SERPINE1+ fibroblasts as potential markers of malignancy. Their findings provide a spatially resolved view of tumor microenvironment remodeling in thyroid cancer.
dlvr.it
March 30, 2025 at 12:27 PM
Online now: A spatially resolved transcriptome landscape during thyroid cancer progression Online now:
Reposted by Renu Dhanasekaran
A metric that reflects reality and the @bluesky platform as the preferred one to transmit science publications with collegial communication
Mike spotted this before the rest of us. 🫡
Publications from 2025 are shared more on Bluesky than on X/Twitter.
Publications from 2025 are shared more on Bluesky than on X/Twitter.
About to talk to medical affairs colleagues, with the news that Bluesky is carrying more posts about new journal publications than X #bluesky #altmetrics #x #xparrot
March 13, 2025 at 11:05 PM
A metric that reflects reality and the @bluesky platform as the preferred one to transmit science publications with collegial communication
Reposted by Renu Dhanasekaran
Two truths and a lie
Truth: There are adverse events from MMR and all vaccines.
Truth: People die, albeit very, very, VERY rarely.
BIG FUCKING LIE: the MMR does NOT cause measles or any sequelae. It prevents measles. It’s safe and effective. Measles disables & kills children. Vaccinate your kids
Truth: There are adverse events from MMR and all vaccines.
Truth: People die, albeit very, very, VERY rarely.
BIG FUCKING LIE: the MMR does NOT cause measles or any sequelae. It prevents measles. It’s safe and effective. Measles disables & kills children. Vaccinate your kids
RFK Jr on the measles vaccine: "There are adverse events from the vaccine. It does cause deaths every year. It causes all the illnesses that measles itself cause."
March 12, 2025 at 2:32 AM
Two truths and a lie
Truth: There are adverse events from MMR and all vaccines.
Truth: People die, albeit very, very, VERY rarely.
BIG FUCKING LIE: the MMR does NOT cause measles or any sequelae. It prevents measles. It’s safe and effective. Measles disables & kills children. Vaccinate your kids
Truth: There are adverse events from MMR and all vaccines.
Truth: People die, albeit very, very, VERY rarely.
BIG FUCKING LIE: the MMR does NOT cause measles or any sequelae. It prevents measles. It’s safe and effective. Measles disables & kills children. Vaccinate your kids
Reposted by Renu Dhanasekaran
We are on our second starter pack for GI / Hepatology
Part 1: go.bsky.app/8Pho2tp
Part 2: go.bsky.app/VGyLKjR
#medsky #GIsky #LiverSky
Part 1: go.bsky.app/8Pho2tp
Part 2: go.bsky.app/VGyLKjR
#medsky #GIsky #LiverSky
March 9, 2025 at 4:52 PM
Reposted by Renu Dhanasekaran
Calling #liversky 📣📣📣
Has anyone seen a woman with severe itching, a low/normal alkphos over 10 years, a biopsy that shows minimal fibrosis, mild interface hepatitis and bile duct injury and a sky high AMA titer, SP-100 and GP-210?
Symptomatic PBC with normal alkphos?
Treat or not?
#Liversky
Symptomatic PBC with normal alkphos?
Treat or not?
#Liversky
March 8, 2025 at 12:39 AM
Calling #liversky 📣📣📣
Reposted by Renu Dhanasekaran
In these unprecedented dark times for American life science and medical research (no less well beyond biomedicine), my coping mechanism is to laser focus on the unremitting and remarkable daily advances, and the fervent hope these will not be slowed or interrupted.
March 6, 2025 at 9:34 PM
In these unprecedented dark times for American life science and medical research (no less well beyond biomedicine), my coping mechanism is to laser focus on the unremitting and remarkable daily advances, and the fervent hope these will not be slowed or interrupted.
Reposted by Renu Dhanasekaran
SCI Member Hanlee Ji & others found that #GastricCancer precursors exhibit variable progression rates. A 26-gene panel was identified, linked to advanced lesions, suggesting immature intestinal cells play a key role in carcinogenesis. www.nature.com/articles/s41...
March 3, 2025 at 5:00 PM
SCI Member Hanlee Ji & others found that #GastricCancer precursors exhibit variable progression rates. A 26-gene panel was identified, linked to advanced lesions, suggesting immature intestinal cells play a key role in carcinogenesis. www.nature.com/articles/s41...
Reposted by Renu Dhanasekaran
Today, a broad coalition of scientific professional societies who represent over 92,000 scientists are speaking out against the politicization and demonization of Federally funded science and government scientist jobs.
It was an honor to help the Union of Concerned Scientists with this! 🧪🌎
It was an honor to help the Union of Concerned Scientists with this! 🧪🌎
48 Scientific Societies Representing Almost 100,000 Scientists Ask Congress to Protect the Future of Science
48 scientific societies representing almost 100,000 scientists signed on to a letter asking Congress to protect the future of science
www.ucsusa.org
March 3, 2025 at 3:52 PM
Today, a broad coalition of scientific professional societies who represent over 92,000 scientists are speaking out against the politicization and demonization of Federally funded science and government scientist jobs.
It was an honor to help the Union of Concerned Scientists with this! 🧪🌎
It was an honor to help the Union of Concerned Scientists with this! 🧪🌎
Reposted by Renu Dhanasekaran
Highlighting role of hepatology in the spectrum of HCC care
In this study
Impact of liver decom on clinical outcomes on atezobeva
📌OS better in CP A vs CP B
📌No differences in TTP/safety
📌Liver decomp: 28% CP A vs 51% CP B
📌41% resume after decomp
#Liversky
www.cghjournal.org/article/S154...
In this study
Impact of liver decom on clinical outcomes on atezobeva
📌OS better in CP A vs CP B
📌No differences in TTP/safety
📌Liver decomp: 28% CP A vs 51% CP B
📌41% resume after decomp
#Liversky
www.cghjournal.org/article/S154...
March 3, 2025 at 4:22 PM
Highlighting role of hepatology in the spectrum of HCC care
In this study
Impact of liver decom on clinical outcomes on atezobeva
📌OS better in CP A vs CP B
📌No differences in TTP/safety
📌Liver decomp: 28% CP A vs 51% CP B
📌41% resume after decomp
#Liversky
www.cghjournal.org/article/S154...
In this study
Impact of liver decom on clinical outcomes on atezobeva
📌OS better in CP A vs CP B
📌No differences in TTP/safety
📌Liver decomp: 28% CP A vs 51% CP B
📌41% resume after decomp
#Liversky
www.cghjournal.org/article/S154...
Reposted by Renu Dhanasekaran
Resembling sand swirling in water, this region of a molecular cloud was observed by #NASAWebb. In mid-infrared light, several dim stars and one bright star with diffraction spikes appear.
Credit: NASA, ESA, CSA, W.R.M. Rocha (LEI). 🔭 🧪
Credit: NASA, ESA, CSA, W.R.M. Rocha (LEI). 🔭 🧪
February 26, 2025 at 5:59 PM
Resembling sand swirling in water, this region of a molecular cloud was observed by #NASAWebb. In mid-infrared light, several dim stars and one bright star with diffraction spikes appear.
Credit: NASA, ESA, CSA, W.R.M. Rocha (LEI). 🔭 🧪
Credit: NASA, ESA, CSA, W.R.M. Rocha (LEI). 🔭 🧪
Reposted by Renu Dhanasekaran
Our new Series on the management of hepatocellular carcinoma is now available at buff.ly/4b3odyq
Papers examine the roles precision surgery, combining locoregional & systemic therapies, and the use of external-beam radiotherapy for patients with hepatocellular carcinoma
#LiverSky #OncSky #MedSky
Papers examine the roles precision surgery, combining locoregional & systemic therapies, and the use of external-beam radiotherapy for patients with hepatocellular carcinoma
#LiverSky #OncSky #MedSky
February 23, 2025 at 11:49 PM
Presently, an estimated 60-70 million Americans are suffering from GI diseases. That is why consistent and sustainable funding from NIH is necessary to support innovative research and treatment development.
Please take a minute to tell Congress to stop NIH cuts!
gastro.quorum.us/campaign/109928
Please take a minute to tell Congress to stop NIH cuts!
gastro.quorum.us/campaign/109928
Tell Congress to Stop Harmful NIH Research Cuts!
Tell Congress to Stop Harmful NIH Research Cuts!
gastro.quorum.us
February 24, 2025 at 12:43 AM
Presently, an estimated 60-70 million Americans are suffering from GI diseases. That is why consistent and sustainable funding from NIH is necessary to support innovative research and treatment development.
Please take a minute to tell Congress to stop NIH cuts!
gastro.quorum.us/campaign/109928
Please take a minute to tell Congress to stop NIH cuts!
gastro.quorum.us/campaign/109928
Reposted by Renu Dhanasekaran
A whole generation of early career scientists and physician-scientists, including colleagues and myself, are particularly vulnerable to these funding freezes and cuts, with jobs and careers depending on federal grants.
#IDsky
#Medsky
#Episky
www.science.org/content/arti...
#IDsky
#Medsky
#Episky
www.science.org/content/arti...
U.S. early-career researchers struggling amid chaos
Uncertain funding, government firings, and distressed universities hit vulnerable groups especially hard
www.science.org
February 22, 2025 at 12:08 PM
A whole generation of early career scientists and physician-scientists, including colleagues and myself, are particularly vulnerable to these funding freezes and cuts, with jobs and careers depending on federal grants.
#IDsky
#Medsky
#Episky
www.science.org/content/arti...
#IDsky
#Medsky
#Episky
www.science.org/content/arti...
Reposted by Renu Dhanasekaran
This trial by @bloompringle.bsky.social will be seen as one of the most important in the field of FMT - 💩 transplant - for #cirrhosis
Does the 💩 engraft?
Does the 💩 work (improved barrier function)?
This is why PPB is the future
journals.lww.com/hepcomm/full...
#liversky
Does the 💩 engraft?
Does the 💩 work (improved barrier function)?
This is why PPB is the future
journals.lww.com/hepcomm/full...
#liversky
Safety and efficacy of a defined bacterial consortium,... : Hepatology Communications
thods:
We performed a single-center, randomized, placebo-controlled trial of VE303 in adult patients with a history of overt HE (NCT04899115). Eligible patients were taking lactulose and rifaximin, ...
journals.lww.com
February 20, 2025 at 1:16 AM
This trial by @bloompringle.bsky.social will be seen as one of the most important in the field of FMT - 💩 transplant - for #cirrhosis
Does the 💩 engraft?
Does the 💩 work (improved barrier function)?
This is why PPB is the future
journals.lww.com/hepcomm/full...
#liversky
Does the 💩 engraft?
Does the 💩 work (improved barrier function)?
This is why PPB is the future
journals.lww.com/hepcomm/full...
#liversky
@NIH needs thoughtful, deliberate, transparent, and accountable reform.
Not this chaos!
Instead of uniting, many are exploiting the crisis to push their own agendas.
This division leaves our community fractured while decades of progress is being recklessly discarded!
Let’s unite our voices !
Not this chaos!
Instead of uniting, many are exploiting the crisis to push their own agendas.
This division leaves our community fractured while decades of progress is being recklessly discarded!
Let’s unite our voices !
February 9, 2025 at 1:50 AM
@NIH needs thoughtful, deliberate, transparent, and accountable reform.
Not this chaos!
Instead of uniting, many are exploiting the crisis to push their own agendas.
This division leaves our community fractured while decades of progress is being recklessly discarded!
Let’s unite our voices !
Not this chaos!
Instead of uniting, many are exploiting the crisis to push their own agendas.
This division leaves our community fractured while decades of progress is being recklessly discarded!
Let’s unite our voices !
Hiring Alert!
We’re looking for a fellow to join our lab at @Stanford_GI and work on cutting-edge research in liver cancer immunobiology.
Help me spread the word, know someone interested? Send them my way! #HCC
postdocs.stanford.edu/prospective/...
We’re looking for a fellow to join our lab at @Stanford_GI and work on cutting-edge research in liver cancer immunobiology.
Help me spread the word, know someone interested? Send them my way! #HCC
postdocs.stanford.edu/prospective/...
February 1, 2025 at 12:55 PM
Hiring Alert!
We’re looking for a fellow to join our lab at @Stanford_GI and work on cutting-edge research in liver cancer immunobiology.
Help me spread the word, know someone interested? Send them my way! #HCC
postdocs.stanford.edu/prospective/...
We’re looking for a fellow to join our lab at @Stanford_GI and work on cutting-edge research in liver cancer immunobiology.
Help me spread the word, know someone interested? Send them my way! #HCC
postdocs.stanford.edu/prospective/...
Reposted by Renu Dhanasekaran
How the environment impacts the liver
And the risk of liver cancer
Phenomenal review in Hep Comm:
journals.lww.com/hepcomm/full...
#liversky #medsky
And the risk of liver cancer
Phenomenal review in Hep Comm:
journals.lww.com/hepcomm/full...
#liversky #medsky
January 26, 2025 at 8:04 PM
How the environment impacts the liver
And the risk of liver cancer
Phenomenal review in Hep Comm:
journals.lww.com/hepcomm/full...
#liversky #medsky
And the risk of liver cancer
Phenomenal review in Hep Comm:
journals.lww.com/hepcomm/full...
#liversky #medsky
Hi #livertwitter! Just joined this place, say hi so I can find you!
January 25, 2025 at 4:58 AM
Hi #livertwitter! Just joined this place, say hi so I can find you!