Elliot Tapper
@ebtapper.bsky.social
Hepatologist. #LiverSky / LiverLand. #MedSky. #cirrhosis
Academic Chief of Hepatology at University of Michigan. Editor, Hepatology Communications. Kid Chauffeur
Academic Chief of Hepatology at University of Michigan. Editor, Hepatology Communications. Kid Chauffeur
Pinned
Elliot Tapper
@ebtapper.bsky.social
· Nov 15
We are on our second starter pack for GI / Hepatology
Part 1: go.bsky.app/8Pho2tp
Part 2: go.bsky.app/VGyLKjR
#medsky #GIsky #LiverSky
Part 1: go.bsky.app/8Pho2tp
Part 2: go.bsky.app/VGyLKjR
#medsky #GIsky #LiverSky
1 in 5 Greek puppies with chronic kidney disease have advanced liver disease and it is the liver disease that is most linked to poor quality of life
August 30, 2025 at 12:52 AM
1 in 5 Greek puppies with chronic kidney disease have advanced liver disease and it is the liver disease that is most linked to poor quality of life
Reposted by Elliot Tapper
New at The Lancet Public Health - Targeting alcohol use in high-risk population groups: a US microsimulation study of beverage-specific pricing policies
www.thelancet.com/journals/lan...
#alcohol #LiverSky #MedSky
www.thelancet.com/journals/lan...
#alcohol #LiverSky #MedSky
Targeting alcohol use in high-risk population groups: a US microsimulation study of beverage-specific pricing policies
Disproportionate increases in retail prices for the cheapest beverages, beer and spirits,
might lead to a greater decline in consumption among high-risk groups. Pricing policies
could thus be used as ...
www.thelancet.com
August 28, 2025 at 10:23 AM
New at The Lancet Public Health - Targeting alcohol use in high-risk population groups: a US microsimulation study of beverage-specific pricing policies
www.thelancet.com/journals/lan...
#alcohol #LiverSky #MedSky
www.thelancet.com/journals/lan...
#alcohol #LiverSky #MedSky
Reposted by Elliot Tapper
Dear #LiverSky #HepatoSky researchers:
PSC Partners grant cycle is now open! The deadline for your LOI is December 1, 2025
Need help crafting your grant? I offer editing services to help strengthen your proposal. Let's work together to make your work stand out!
pscpartners.org/research/res...
PSC Partners grant cycle is now open! The deadline for your LOI is December 1, 2025
Need help crafting your grant? I offer editing services to help strengthen your proposal. Let's work together to make your work stand out!
pscpartners.org/research/res...
PSC Grant Application | Liver Research Grants | PSC Partners Seeking a Cure
Are you researching PSC? Do you need your medical research funded? At PSC Partners, we award grants to researchers answering important questions related to PSC. Apply.
pscpartners.org
August 18, 2025 at 9:56 PM
Dear #LiverSky #HepatoSky researchers:
PSC Partners grant cycle is now open! The deadline for your LOI is December 1, 2025
Need help crafting your grant? I offer editing services to help strengthen your proposal. Let's work together to make your work stand out!
pscpartners.org/research/res...
PSC Partners grant cycle is now open! The deadline for your LOI is December 1, 2025
Need help crafting your grant? I offer editing services to help strengthen your proposal. Let's work together to make your work stand out!
pscpartners.org/research/res...
Reposted by Elliot Tapper
More #efruxifermin data this time in #MASH F2/F3 fibrosis @ 96 weeks
✅ Efficacy w/ dose dependent response (sort of) and NITs consistent
↔️ not crazy about mITT though it is mentioned no paired bx= non responders
⬇️ dose dependent reduction in bone mineral density
#liversky
✅ Efficacy w/ dose dependent response (sort of) and NITs consistent
↔️ not crazy about mITT though it is mentioned no paired bx= non responders
⬇️ dose dependent reduction in bone mineral density
#liversky
"Safety and efficacy of once-weekly efruxifermin versus placebo in metabolic dysfunction-associated steatohepatitis (HARMONY): 96-week results from a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial.
Publié ce jour dans @thelancet.com
www.thelancet.com/journals/lan...
Publié ce jour dans @thelancet.com
www.thelancet.com/journals/lan...
Safety and efficacy of once-weekly efruxifermin versus placebo in metabolic dysfunction-associated steatohepatitis (HARMONY): 96-week results from a multicentre, randomised, double-blind, placebo-cont...
Efruxifermin resulted in greater improvements in fibrosis than placebo after 96 weeks,
warranting further investigation in phase 3 trials.
www.thelancet.com
August 18, 2025 at 10:46 PM
More #efruxifermin data this time in #MASH F2/F3 fibrosis @ 96 weeks
✅ Efficacy w/ dose dependent response (sort of) and NITs consistent
↔️ not crazy about mITT though it is mentioned no paired bx= non responders
⬇️ dose dependent reduction in bone mineral density
#liversky
✅ Efficacy w/ dose dependent response (sort of) and NITs consistent
↔️ not crazy about mITT though it is mentioned no paired bx= non responders
⬇️ dose dependent reduction in bone mineral density
#liversky
Reposted by Elliot Tapper
New hope for #liverhealth: FDA recently approved Wegovy as the 1st #GLP1 therapy for adults with serious #liverdisease. Research presented at TLM ‘24 demonstrated the groundbreaking treatment potential. Learn more: https://bit.ly/45phv4R
August 19, 2025 at 5:00 PM
New hope for #liverhealth: FDA recently approved Wegovy as the 1st #GLP1 therapy for adults with serious #liverdisease. Research presented at TLM ‘24 demonstrated the groundbreaking treatment potential. Learn more: https://bit.ly/45phv4R
When did I start rounding?
August 6, 2025 at 9:22 PM
When did I start rounding?
Reposted by Elliot Tapper
🥾A reboot with endless pearls!
#452 NAFLD/MASLD! Expand your NAFLD/MASLD knowledge!
Expert guest @ebtapper.bsky.social shares his framework for approaching NAFLD/MASLD and the treatment tools he recommends including lifestyle modifications and medications.
www.thecurbsiders.com
#452 NAFLD/MASLD! Expand your NAFLD/MASLD knowledge!
Expert guest @ebtapper.bsky.social shares his framework for approaching NAFLD/MASLD and the treatment tools he recommends including lifestyle modifications and medications.
www.thecurbsiders.com
August 4, 2025 at 7:34 PM
🥾A reboot with endless pearls!
#452 NAFLD/MASLD! Expand your NAFLD/MASLD knowledge!
Expert guest @ebtapper.bsky.social shares his framework for approaching NAFLD/MASLD and the treatment tools he recommends including lifestyle modifications and medications.
www.thecurbsiders.com
#452 NAFLD/MASLD! Expand your NAFLD/MASLD knowledge!
Expert guest @ebtapper.bsky.social shares his framework for approaching NAFLD/MASLD and the treatment tools he recommends including lifestyle modifications and medications.
www.thecurbsiders.com
Reposted by Elliot Tapper
my take on procal:
1. zero role in ED, shouldn't be used to start ABX
2. CAN be super helpful in first 24 hr after ICU admit to help disprove sepsis in complex cases (eg aspiration pneumonitis or atelectasis masquerading as PNA). helps stop ABX & redirect.
3. not helpful in limiting ABX duration
1. zero role in ED, shouldn't be used to start ABX
2. CAN be super helpful in first 24 hr after ICU admit to help disprove sepsis in complex cases (eg aspiration pneumonitis or atelectasis masquerading as PNA). helps stop ABX & redirect.
3. not helpful in limiting ABX duration
📉 Does trending biomarkers help stop antibiotics sooner safely in sepsis?
👀 More here: https://wp.me/pdrP8b-5mL
#FOAMed #EMIMCC #MedSky
👀 More here: https://wp.me/pdrP8b-5mL
#FOAMed #EMIMCC #MedSky
July 31, 2025 at 12:59 PM
my take on procal:
1. zero role in ED, shouldn't be used to start ABX
2. CAN be super helpful in first 24 hr after ICU admit to help disprove sepsis in complex cases (eg aspiration pneumonitis or atelectasis masquerading as PNA). helps stop ABX & redirect.
3. not helpful in limiting ABX duration
1. zero role in ED, shouldn't be used to start ABX
2. CAN be super helpful in first 24 hr after ICU admit to help disprove sepsis in complex cases (eg aspiration pneumonitis or atelectasis masquerading as PNA). helps stop ABX & redirect.
3. not helpful in limiting ABX duration
Reposted by Elliot Tapper
🚨 High Yield Infographic Alert!
Elevated PTT? Think bleeding history.
🟢 Non-bleeders: APS, contact factor deficiencies, heparin.
🔴 Bleeders: Hemophilias, vWD, factor VIII inhibitors.
Not all prolonged PTTs mean bleeding risk.
#MedEd #Hematology #FOAMed #ElevatedPTT #TheCurbsiders
Elevated PTT? Think bleeding history.
🟢 Non-bleeders: APS, contact factor deficiencies, heparin.
🔴 Bleeders: Hemophilias, vWD, factor VIII inhibitors.
Not all prolonged PTTs mean bleeding risk.
#MedEd #Hematology #FOAMed #ElevatedPTT #TheCurbsiders
July 16, 2025 at 12:57 AM
🚨 High Yield Infographic Alert!
Elevated PTT? Think bleeding history.
🟢 Non-bleeders: APS, contact factor deficiencies, heparin.
🔴 Bleeders: Hemophilias, vWD, factor VIII inhibitors.
Not all prolonged PTTs mean bleeding risk.
#MedEd #Hematology #FOAMed #ElevatedPTT #TheCurbsiders
Elevated PTT? Think bleeding history.
🟢 Non-bleeders: APS, contact factor deficiencies, heparin.
🔴 Bleeders: Hemophilias, vWD, factor VIII inhibitors.
Not all prolonged PTTs mean bleeding risk.
#MedEd #Hematology #FOAMed #ElevatedPTT #TheCurbsiders
Reposted by Elliot Tapper
Another piece of evidence about the role of anticoagulants in cirrhosis. Results of a multicenter effort. The cirroxaban study. @hospitalclinic.bsky.social @idibaps.bsky.social @jhepatology.bsky.social
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
ScienceDirect.com | Science, health and medical journals, full text articles and books.
kwnsfk27.r.eu-west-1.awstrack.me
July 20, 2025 at 10:02 AM
Another piece of evidence about the role of anticoagulants in cirrhosis. Results of a multicenter effort. The cirroxaban study. @hospitalclinic.bsky.social @idibaps.bsky.social @jhepatology.bsky.social
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
Reposted by Elliot Tapper
Jaume Bosch
No one, and I mean no one, made more seminal contributions to the measurement, interpretation & clinical applications of HVPG, the prognostic impact of CSPH and its rx.
Truly in the pantheon of all time greatest hepatologists and a kind, generous person on top.
RIP
#liversky
No one, and I mean no one, made more seminal contributions to the measurement, interpretation & clinical applications of HVPG, the prognostic impact of CSPH and its rx.
Truly in the pantheon of all time greatest hepatologists and a kind, generous person on top.
RIP
#liversky
July 17, 2025 at 2:54 AM
Jaume Bosch
No one, and I mean no one, made more seminal contributions to the measurement, interpretation & clinical applications of HVPG, the prognostic impact of CSPH and its rx.
Truly in the pantheon of all time greatest hepatologists and a kind, generous person on top.
RIP
#liversky
No one, and I mean no one, made more seminal contributions to the measurement, interpretation & clinical applications of HVPG, the prognostic impact of CSPH and its rx.
Truly in the pantheon of all time greatest hepatologists and a kind, generous person on top.
RIP
#liversky
Ask my kids what my goals are - though I am consistent, they will tell you the order is reversed
LIFE GOALS
1. Raise happy children
2. Be old dude at grand rounds who falls asleep
1. Raise happy children
2. Be old dude at grand rounds who falls asleep
July 19, 2025 at 8:54 PM
Ask my kids what my goals are - though I am consistent, they will tell you the order is reversed
LIFE GOALS
1. Raise happy children
2. Be old dude at grand rounds who falls asleep
1. Raise happy children
2. Be old dude at grand rounds who falls asleep
July 19, 2025 at 8:48 PM
LIFE GOALS
1. Raise happy children
2. Be old dude at grand rounds who falls asleep
1. Raise happy children
2. Be old dude at grand rounds who falls asleep
Daughter wearing a Jean jacket for our day trip to Canada
July 19, 2025 at 12:01 PM
Daughter wearing a Jean jacket for our day trip to Canada
Reposted by Elliot Tapper
I am very sad. My mentor and friend, Jaume Bosch, just has passed away. Thanks for everything, I will miss you. I would always remember our last day together celebrating a journey we begin together @hospitalclinic.bsky.social @idibaps.bsky.social
July 15, 2025 at 6:02 PM
I am very sad. My mentor and friend, Jaume Bosch, just has passed away. Thanks for everything, I will miss you. I would always remember our last day together celebrating a journey we begin together @hospitalclinic.bsky.social @idibaps.bsky.social
doi:10.1001/jamanetworkopen.2025.19426
July 14, 2025 at 12:19 AM
doi:10.1001/jamanetworkopen.2025.19426
Wake up new cause of liver enzyme elevation just dropped
July 9, 2025 at 10:41 AM
Wake up new cause of liver enzyme elevation just dropped
They are establishing upper limits of normal for ammonia in pets
Thank you for your attention to this matter!
Thank you for your attention to this matter!
June 28, 2025 at 2:26 PM
They are establishing upper limits of normal for ammonia in pets
Thank you for your attention to this matter!
Thank you for your attention to this matter!
podcasts.apple.com/us/podcast/l...
Gideon is the best of us.
Truly infectious enthusiasm for hepatology
👇 management of pbc
👇 clinical philosophy
👇 how to build a research career
Gideon is the best of us.
Truly infectious enthusiasm for hepatology
👇 management of pbc
👇 clinical philosophy
👇 how to build a research career
The Latest in PBC with Gideon Hirschfield
Podcast Episode · Liver Talks: The Liver Fellow Network Podcast · 06/17/2025 · 35m
podcasts.apple.com
June 25, 2025 at 11:46 AM
podcasts.apple.com/us/podcast/l...
Gideon is the best of us.
Truly infectious enthusiasm for hepatology
👇 management of pbc
👇 clinical philosophy
👇 how to build a research career
Gideon is the best of us.
Truly infectious enthusiasm for hepatology
👇 management of pbc
👇 clinical philosophy
👇 how to build a research career
Reposted by Elliot Tapper
Recently had @ebtapper.bsky.social on the Critical Care Scenarios podcast talking GI and this topic came up.
icuscenarios.com/lightning-ro...
icuscenarios.com/lightning-ro...
Lightning rounds 53: GI Q&A with Elliot Tapper – Critical Care Scenarios
icuscenarios.com
June 18, 2025 at 11:33 AM
Recently had @ebtapper.bsky.social on the Critical Care Scenarios podcast talking GI and this topic came up.
icuscenarios.com/lightning-ro...
icuscenarios.com/lightning-ro...
Cardiovascular risk estimates miss the mark in people with MASH
Heart disease is the most important risk for patients with MASH but the commonly used risk equations just don’t work
New paper in the red journal @amcollegegastro.bsky.social
journals.lww.com/ajg/abstract...
Heart disease is the most important risk for patients with MASH but the commonly used risk equations just don’t work
New paper in the red journal @amcollegegastro.bsky.social
journals.lww.com/ajg/abstract...
Cardiovascular risk assessment tools are insufficient for... : Official journal of the American College of Gastroenterology | ACG
tudy sought to determine the accuracy of the FRS, PCE, and PREVENT in a real-world cohort of patients with MASLD.
Methods:
This analysis included US adults ≥ age 30 with MASLD in the TARGET-NASH st...
journals.lww.com
June 15, 2025 at 8:09 PM
Cardiovascular risk estimates miss the mark in people with MASH
Heart disease is the most important risk for patients with MASH but the commonly used risk equations just don’t work
New paper in the red journal @amcollegegastro.bsky.social
journals.lww.com/ajg/abstract...
Heart disease is the most important risk for patients with MASH but the commonly used risk equations just don’t work
New paper in the red journal @amcollegegastro.bsky.social
journals.lww.com/ajg/abstract...
Dear FreelyFiltered
I am a listener of the podcast. I listen for the humans. And their input. I think the AI podcast on the NephJC was a nice as a way for me to hear about a trial and trial discussion I would have missed but the info didnt stick for this adult learner
@kidneyboy.bsky.social
I am a listener of the podcast. I listen for the humans. And their input. I think the AI podcast on the NephJC was a nice as a way for me to hear about a trial and trial discussion I would have missed but the info didnt stick for this adult learner
@kidneyboy.bsky.social
June 14, 2025 at 4:27 PM
Dear FreelyFiltered
I am a listener of the podcast. I listen for the humans. And their input. I think the AI podcast on the NephJC was a nice as a way for me to hear about a trial and trial discussion I would have missed but the info didnt stick for this adult learner
@kidneyboy.bsky.social
I am a listener of the podcast. I listen for the humans. And their input. I think the AI podcast on the NephJC was a nice as a way for me to hear about a trial and trial discussion I would have missed but the info didnt stick for this adult learner
@kidneyboy.bsky.social
Hepatic encephalopathy is horrible
It can present as disorientation and coma. But often causes poor quality of life, falls, and other trauma
We want to prevent it. How can we predict it?
It can present as disorientation and coma. But often causes poor quality of life, falls, and other trauma
We want to prevent it. How can we predict it?
June 14, 2025 at 4:19 PM
Hepatic encephalopathy is horrible
It can present as disorientation and coma. But often causes poor quality of life, falls, and other trauma
We want to prevent it. How can we predict it?
It can present as disorientation and coma. But often causes poor quality of life, falls, and other trauma
We want to prevent it. How can we predict it?