Renu Dhanasekaran
@renumathyd.bsky.social
Physician scientist at Stanford University
Passionate about liver cancer research
Transplant Hepatologist
Co-Founder Arithmedics
Passionate about liver cancer research
Transplant Hepatologist
Co-Founder Arithmedics
Great to see all the updates you are posting, keep it coming!
October 14, 2025 at 1:49 AM
Great to see all the updates you are posting, keep it coming!
The stiffness is likely just reflecting the inflammation?
October 14, 2025 at 1:45 AM
The stiffness is likely just reflecting the inflammation?
We do not routinely biopsy but we are doing it more often than before.
I am big proponent for biopsy before systemic therapy as wrote in this review pmc.ncbi.nlm.nih.gov/articles/PMC....
But I still do not think the evidence is strong enough to make it into the guidelines.
I am big proponent for biopsy before systemic therapy as wrote in this review pmc.ncbi.nlm.nih.gov/articles/PMC....
But I still do not think the evidence is strong enough to make it into the guidelines.
Battle of the biopsies: Role of tissue and liquid biopsy in hepatocellular carcinoma
The diagnosis and management of hepatocellular carcinoma (HCC) have improved significantly in recent years. With the introduction of immunotherapy-based combination therapy, there has been a notable e...
pmc.ncbi.nlm.nih.gov
April 9, 2025 at 12:45 PM
We do not routinely biopsy but we are doing it more often than before.
I am big proponent for biopsy before systemic therapy as wrote in this review pmc.ncbi.nlm.nih.gov/articles/PMC....
But I still do not think the evidence is strong enough to make it into the guidelines.
I am big proponent for biopsy before systemic therapy as wrote in this review pmc.ncbi.nlm.nih.gov/articles/PMC....
But I still do not think the evidence is strong enough to make it into the guidelines.
Anything new happened there?
March 14, 2025 at 7:07 PM
Anything new happened there?
Interesting, what was the GGT? I haven’t seen this in my practice, but apparently can happen rarely, here is a nice study pubmed.ncbi.nlm.nih.gov/33229138/
Primary biliary cholangitis with normal alkaline phosphatase: A neglected clinical entity challenging current guidelines - PubMed
In our series, a high proportion of AMA positive patients with normal ALP levels have PBC. For the first time we show histological diagnosis of PBC in AMA-negative/PBC-specific ANA-positive subjects a...
pubmed.ncbi.nlm.nih.gov
March 8, 2025 at 2:06 AM
Interesting, what was the GGT? I haven’t seen this in my practice, but apparently can happen rarely, here is a nice study pubmed.ncbi.nlm.nih.gov/33229138/
Why not treat all the large varices? Is the idea to decrease risk of post banding ulcer bleed? And unless it’s actively spurting at the time of scope, it’s not always obvious which the bleeder is, right?
March 4, 2025 at 3:20 AM
Why not treat all the large varices? Is the idea to decrease risk of post banding ulcer bleed? And unless it’s actively spurting at the time of scope, it’s not always obvious which the bleeder is, right?
It affects all of us!
February 24, 2025 at 12:46 AM
It affects all of us!