Rebecca Ann Jones
@rebannjones.bsky.social
Post-doctoral researcher at Princeton University. PhD from The Francis Crick Institute. Developmental cell biology to better understand human disease. Fascinated by how cells move. She/her.
Reposted by Rebecca Ann Jones
Thrilled to share that we have been awarded a Wellcome DA to explore cytoneme-based cell communication in development! A fantastic collaboration with Kyle @kylewedgwood.bsky.social at @lsiexeter.bsky.social, and Hilary Ashe & Cerys Manning at Manchester - exciting times ahead! tinyurl.com/2ytm6y2w
Exeter researchers awarded £3.5M to uncover how cells communicate during development
Researchers at the Living Systems Institute (LSI), University of Exeter, have been awarded a £3.5 million Wellcome Discovery Award to investigate how cells exchange information to coordinate the forma...
tinyurl.com
November 10, 2025 at 2:13 PM
Thrilled to share that we have been awarded a Wellcome DA to explore cytoneme-based cell communication in development! A fantastic collaboration with Kyle @kylewedgwood.bsky.social at @lsiexeter.bsky.social, and Hilary Ashe & Cerys Manning at Manchester - exciting times ahead! tinyurl.com/2ytm6y2w
The scientist who made 'magic' real for me and inspired my love of developmental biology. A sad day and a huge loss.
www.cam.ac.uk/research/new...
www.cam.ac.uk/research/new...
Nobel Laureate Professor Sir John Gurdon dies aged 92
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.
www.cam.ac.uk
October 10, 2025 at 11:54 AM
The scientist who made 'magic' real for me and inspired my love of developmental biology. A sad day and a huge loss.
www.cam.ac.uk/research/new...
www.cam.ac.uk/research/new...
I absolutely loved my time at @crick.ac.uk with @jimsmith31.bsky.social I can't recommend this program enough 🙂
2026 PhD recruitment is now open.
As well as our main PhD recruitment, which is open to all, we are pleased to be offering scholarships for candidates of Black or mixed Black heritage. Learn more and apply on our website:
www.crick.ac.uk/careers-stud...
As well as our main PhD recruitment, which is open to all, we are pleased to be offering scholarships for candidates of Black or mixed Black heritage. Learn more and apply on our website:
www.crick.ac.uk/careers-stud...
PhD student recruitment
PhD recruitment information.
www.crick.ac.uk
October 7, 2025 at 3:23 PM
I absolutely loved my time at @crick.ac.uk with @jimsmith31.bsky.social I can't recommend this program enough 🙂
Reposted by Rebecca Ann Jones
🚨🚨 We're hiring! 🚨🚨
The Single-cell Analytics Innovation Lab (SAIL) at @mskcancercenter.bsky.social is looking for a Junior Technician to join our wet lab team!
You'll work with spatial genomics and single-cell technologies, helping us push the boundaries of cutting-edge analysis in cancer research.
The Single-cell Analytics Innovation Lab (SAIL) at @mskcancercenter.bsky.social is looking for a Junior Technician to join our wet lab team!
You'll work with spatial genomics and single-cell technologies, helping us push the boundaries of cutting-edge analysis in cancer research.
June 23, 2025 at 8:27 PM
🚨🚨 We're hiring! 🚨🚨
The Single-cell Analytics Innovation Lab (SAIL) at @mskcancercenter.bsky.social is looking for a Junior Technician to join our wet lab team!
You'll work with spatial genomics and single-cell technologies, helping us push the boundaries of cutting-edge analysis in cancer research.
The Single-cell Analytics Innovation Lab (SAIL) at @mskcancercenter.bsky.social is looking for a Junior Technician to join our wet lab team!
You'll work with spatial genomics and single-cell technologies, helping us push the boundaries of cutting-edge analysis in cancer research.
Reposted by Rebecca Ann Jones
Our first extraordinary biologist for this week is Jim Smith, former Editor-in-Chief of @dev-journal.bsky.social and @biologists.bsky.social Director, who was also part of the Biologists @ 100 organising committee. #100biologists
June 17, 2025 at 2:09 PM
Our first extraordinary biologist for this week is Jim Smith, former Editor-in-Chief of @dev-journal.bsky.social and @biologists.bsky.social Director, who was also part of the Biologists @ 100 organising committee. #100biologists
Reposted by Rebecca Ann Jones
What do we see when looking at cells under the microscope? 👉Some are bigger than others, some are elongated and align with the neighbors & others seem to move. Cool, right? But wouldn't it be cooler to quantify these observations?
I'm @juliaeckert.bsky.social. Let's explore some analysis software!
I'm @juliaeckert.bsky.social. Let's explore some analysis software!
June 8, 2025 at 7:01 AM
What do we see when looking at cells under the microscope? 👉Some are bigger than others, some are elongated and align with the neighbors & others seem to move. Cool, right? But wouldn't it be cooler to quantify these observations?
I'm @juliaeckert.bsky.social. Let's explore some analysis software!
I'm @juliaeckert.bsky.social. Let's explore some analysis software!
Reposted by Rebecca Ann Jones
Proseg is a segmentation tool for single-cell spatial transcriptomics data that uses unsupervised probabilistic modeling of transcript spatial distribution, for accurate segmentation without multimodal staining.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
May 23, 2025 at 1:35 PM
Proseg is a segmentation tool for single-cell spatial transcriptomics data that uses unsupervised probabilistic modeling of transcript spatial distribution, for accurate segmentation without multimodal staining.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
@david-j-barry.bsky.social perfectly summarizes this - very flattered to see our work featured at the top of the EMBL-EBI AI Ready list @bioimagearchive.bsky.social. A truly fruitful cross-disciplinary collaboration made possible by the incredibly talented STP scientists at @crick.ac.uk 🔬💻🐟!
It's not something we had in mind when assembling this data with @rebannjones.bsky.social, but it's very gratifying and flattering to see our zebrafish embryo images and annotations feature at the top of the AI Ready list presented by @bioimagearchive.bsky.social
www.ebi.ac.uk/bioimage-arc...
www.ebi.ac.uk/bioimage-arc...
BioImageArchive < The European Bioinformatics Institute < EMBL-EBI
The BioImageArchive – a free, publicly available online resource which stores and distributes biological images
www.ebi.ac.uk
May 27, 2025 at 3:18 PM
@david-j-barry.bsky.social perfectly summarizes this - very flattered to see our work featured at the top of the EMBL-EBI AI Ready list @bioimagearchive.bsky.social. A truly fruitful cross-disciplinary collaboration made possible by the incredibly talented STP scientists at @crick.ac.uk 🔬💻🐟!
Reposted by Rebecca Ann Jones
We’re excited to share the first publication from our lab, now out in @EMBOPress! @shayma-a.bsky.social @ucl.ac.uk
Using live imaging in the mouse embryo, we tracked how heart progenitors migrate and assemble into the heart tube.
Using live imaging in the mouse embryo, we tracked how heart progenitors migrate and assemble into the heart tube.
Early coordination of cell migration and cardiac fate determination during mammalian gastrulation, revealed by light-sheet microscopy tracking of individual mesodermal cells
#RefereedPreprint c/o @reviewcommons.org by @kenzoivanovitch.bsky.social and colleagues
www.embopress.org/doi/full/10....
#RefereedPreprint c/o @reviewcommons.org by @kenzoivanovitch.bsky.social and colleagues
www.embopress.org/doi/full/10....
May 13, 2025 at 5:30 PM
We’re excited to share the first publication from our lab, now out in @EMBOPress! @shayma-a.bsky.social @ucl.ac.uk
Using live imaging in the mouse embryo, we tracked how heart progenitors migrate and assemble into the heart tube.
Using live imaging in the mouse embryo, we tracked how heart progenitors migrate and assemble into the heart tube.
Reposted by Rebecca Ann Jones
📢New publication alert!
Exciting new research on start points for DNA replication in human cells by Dr Torsten Krude, students here in Zoology and colleagues @crick.ac.uk
Read more about it: bit.ly/3F1PYvN
Exciting new research on start points for DNA replication in human cells by Dr Torsten Krude, students here in Zoology and colleagues @crick.ac.uk
Read more about it: bit.ly/3F1PYvN
May 9, 2025 at 4:35 PM
📢New publication alert!
Exciting new research on start points for DNA replication in human cells by Dr Torsten Krude, students here in Zoology and colleagues @crick.ac.uk
Read more about it: bit.ly/3F1PYvN
Exciting new research on start points for DNA replication in human cells by Dr Torsten Krude, students here in Zoology and colleagues @crick.ac.uk
Read more about it: bit.ly/3F1PYvN
Reposted by Rebecca Ann Jones
We found that cells use emergent collective memory—arising from simple chemical reactions—to outperform physical limits of detecting chemical gradients. Curious how? 1/n
8 min talk: www.youtube.com/watch?v=A7XH...
bioRxiv: www.biorxiv.org/content/10.1...
#biophysics #cellbiology
8 min talk: www.youtube.com/watch?v=A7XH...
bioRxiv: www.biorxiv.org/content/10.1...
#biophysics #cellbiology
Local collective memory from ratiometric signaling outperforms cellular gradient sensing limits
YouTube video by Debraj Shubham Ghose
www.youtube.com
May 5, 2025 at 10:11 AM
We found that cells use emergent collective memory—arising from simple chemical reactions—to outperform physical limits of detecting chemical gradients. Curious how? 1/n
8 min talk: www.youtube.com/watch?v=A7XH...
bioRxiv: www.biorxiv.org/content/10.1...
#biophysics #cellbiology
8 min talk: www.youtube.com/watch?v=A7XH...
bioRxiv: www.biorxiv.org/content/10.1...
#biophysics #cellbiology
Ahhh cell migration, so much cool reading to do!
If you're curious about how cells make decisions in complex environments, and how mathematical models can capture such behaviour, our preprint is now live!
Check it out here: www.biorxiv.org/content/10.1...
Check it out here: www.biorxiv.org/content/10.1...
Investigating Local Negative Feedback of Rac Activity by Mathematical Models and Cell Motility Simulations
For polarization and directed migration, cells use a combination of local positive feedback and long-range inhibition. We have previously used mathematical models to show the ability of this core…
www.biorxiv.org
May 6, 2025 at 10:02 PM
Ahhh cell migration, so much cool reading to do!
What governs where DNA replication begins in human cells? Here, we show that origins of replication in human DNA are epigenetically specified and that crucially, this epigenetic mark is required for both DNA replication and cell proliferation! @narjournal.bsky.social academic.oup.com/nar/article/...
May 6, 2025 at 9:39 PM
What governs where DNA replication begins in human cells? Here, we show that origins of replication in human DNA are epigenetically specified and that crucially, this epigenetic mark is required for both DNA replication and cell proliferation! @narjournal.bsky.social academic.oup.com/nar/article/...
Reposted by Rebecca Ann Jones
What drives cytoplasmic mRNA organization? We created unbiased, genome-wide maps of mesoscale RNA-RNA spatial proximity, revealing impact of encoded protein function. Fantastic work from @lindsayabecker.bsky.social @sofiquinodoz.bsky.social @davidaknowles.bsky.social www.biorxiv.org/content/10.1...
Genome-wide mapping of mesoscale neuronal RNA organization and condensation
Subcellular RNA organization can affect critical cellular functions. However, our understanding of RNA microenvironments, particularly biomolecular condensates, remains limited, largely due to a lack ...
www.biorxiv.org
April 21, 2025 at 1:48 PM
What drives cytoplasmic mRNA organization? We created unbiased, genome-wide maps of mesoscale RNA-RNA spatial proximity, revealing impact of encoded protein function. Fantastic work from @lindsayabecker.bsky.social @sofiquinodoz.bsky.social @davidaknowles.bsky.social www.biorxiv.org/content/10.1...
Reposted by Rebecca Ann Jones
Calling all...
🔬 Microscopists
💻 BioImage Analysts
👩🔬 Life Scientists
📅 Save the Date
The 5th edition of the Crick BioImage Analysis Symposium will take place on November 24/25th 2025.
More details to follow...
#CBIAS2025
🔬 Microscopists
💻 BioImage Analysts
👩🔬 Life Scientists
📅 Save the Date
The 5th edition of the Crick BioImage Analysis Symposium will take place on November 24/25th 2025.
More details to follow...
#CBIAS2025
March 17, 2025 at 8:19 PM
Calling all...
🔬 Microscopists
💻 BioImage Analysts
👩🔬 Life Scientists
📅 Save the Date
The 5th edition of the Crick BioImage Analysis Symposium will take place on November 24/25th 2025.
More details to follow...
#CBIAS2025
🔬 Microscopists
💻 BioImage Analysts
👩🔬 Life Scientists
📅 Save the Date
The 5th edition of the Crick BioImage Analysis Symposium will take place on November 24/25th 2025.
More details to follow...
#CBIAS2025
Reposted by Rebecca Ann Jones
Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...
Measuring and manipulating mechanical forces during development - Nature Cell Biology
This Review discusses the recent advances in experimental approaches to interrogate the mechanical forces that mediate tissue deformations during development, highlighting the insights afforded at bot...
www.nature.com
March 10, 2025 at 1:33 PM
Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...
Watch this space for some fascinating science! Excited to see this, congratulations @tsakiridis.bsky.social 🥼🔬!
I am grateful to @cancerresearchuk.org for choosing to support our work aiming to understand the links between distorted embryonic development and neuroblastoma initiation using our human pluripotent stem cell differentiation model: www.sheffield.ac.uk/biosciences/...
Understanding the genetic roots of aggressive childhood cancer: Research aims to improve Neuroblastoma treatment
Scientists have secured £1.5 million from Cancer Research UK (CRUK) to investigate the genetic secrets behind neuroblastoma - aiming to improve treatments for this aggressive childhood cancer.
www.sheffield.ac.uk
March 6, 2025 at 8:52 PM
Watch this space for some fascinating science! Excited to see this, congratulations @tsakiridis.bsky.social 🥼🔬!
Reposted by Rebecca Ann Jones
Welcome to the Bluesky account for Stand Up for Science 2025!
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
February 12, 2025 at 5:04 PM
Welcome to the Bluesky account for Stand Up for Science 2025!
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide!
#scienceforall #sciencenotsilence
This! I've seen this a couple of times at conferences from established, well-known PIs and it is amazing. It's also a great opportunity to network with them and talk science.
I'd love to see more PIs give poster presentations at conferences.
Not just because I want to see more trainees giving the talks, but also because we should remove that stigma that posters are "lesser things".
Maybe we should try something at @molbiosystems.bsky.social
Not just because I want to see more trainees giving the talks, but also because we should remove that stigma that posters are "lesser things".
Maybe we should try something at @molbiosystems.bsky.social
February 21, 2025 at 9:02 PM
This! I've seen this a couple of times at conferences from established, well-known PIs and it is amazing. It's also a great opportunity to network with them and talk science.
Reposted by Rebecca Ann Jones
Here it is, in collaboration with @lankylaste.bsky.social, Lina Gerontogianni & Gavin Kelly: www.biorxiv.org/content/10.1...
* Stats tests often used inappropriately
* Masses of data points are often unnecessary
* Inferring biological significance almost impossible without appropriate controls
* Stats tests often used inappropriately
* Masses of data points are often unnecessary
* Inferring biological significance almost impossible without appropriate controls
February 11, 2025 at 3:00 PM
Here it is, in collaboration with @lankylaste.bsky.social, Lina Gerontogianni & Gavin Kelly: www.biorxiv.org/content/10.1...
* Stats tests often used inappropriately
* Masses of data points are often unnecessary
* Inferring biological significance almost impossible without appropriate controls
* Stats tests often used inappropriately
* Masses of data points are often unnecessary
* Inferring biological significance almost impossible without appropriate controls
Reposted by Rebecca Ann Jones
OK this is super-cool. I want to try it immediately! www.nature.com/articles/s41...
Live imaging of the extracellular matrix with a glycan-binding fluorophore - Nature Methods
Rhobo6 is a cell-impermeable small-molecule fluorophore that displays reversible fluorogenic binding to glycans, making it a general, wash-free, and non-perturbative label for the extracellular matrix...
www.nature.com
February 6, 2025 at 4:12 PM
OK this is super-cool. I want to try it immediately! www.nature.com/articles/s41...
Amazing opportunity with an amazing scientist/person!
I am recruiting an #ERC funded PostDoc to work on the evolution of vertebral counts in cichlids. This is an experimental project & will be looking for candidates with experience generating reporter lines, live-imaging and experimental embryology.
Application deadline: 25th Feb.
tinyurl.com/33jbu8fa
Application deadline: 25th Feb.
tinyurl.com/33jbu8fa
February 6, 2025 at 4:05 PM
Amazing opportunity with an amazing scientist/person!
Reposted by Rebecca Ann Jones
The #nucleus contains the info of a #cell, but it does much more than that !!
Since the nucleus is *big*, acts as the main intracellular obstacle, and during #CellMigration can get 'trapped'/stuck until the cell pushes it FWD.
#scicomm @focalplane.bsky.social @cellcommlab.bsky.social
#Skyscience
Since the nucleus is *big*, acts as the main intracellular obstacle, and during #CellMigration can get 'trapped'/stuck until the cell pushes it FWD.
#scicomm @focalplane.bsky.social @cellcommlab.bsky.social
#Skyscience
February 1, 2025 at 3:45 PM
The #nucleus contains the info of a #cell, but it does much more than that !!
Since the nucleus is *big*, acts as the main intracellular obstacle, and during #CellMigration can get 'trapped'/stuck until the cell pushes it FWD.
#scicomm @focalplane.bsky.social @cellcommlab.bsky.social
#Skyscience
Since the nucleus is *big*, acts as the main intracellular obstacle, and during #CellMigration can get 'trapped'/stuck until the cell pushes it FWD.
#scicomm @focalplane.bsky.social @cellcommlab.bsky.social
#Skyscience