Nicolas Guyon
@nicolasguyon.bsky.social
Vetenskapsrådet Postdoctoral Fellow at @espciparispsl.bsky.social.
ex PhD in neuroscience in Carlén Lab at @ki.se.
➡️ https://faurelab.cnrs.fr/?page_id=857
ex PhD in neuroscience in Carlén Lab at @ki.se.
➡️ https://faurelab.cnrs.fr/?page_id=857
Pinned
Nicolas Guyon
@nicolasguyon.bsky.social
· Apr 21
The interpeduncular nucleus blunts the rewarding effect of nicotine
Nicotine activates the dopamine reward system to promote consumption and addiction,
but the brain has a natural brake to counteract it. Jehl, Ciscato, Vicq, Guyon, et al.
identified the interpeduncula...
www.cell.com
Super happy to see our new study, on how the interpeduncular nucleus (IPN) regulates nicotine reward, out today in @cp-neuron.bsky.social!
Using #chemogenetics, we @faurelab.bsky.social show that blocking IPN activation enhances VTA responses and increases nicotine's rewarding effect.
#neuroscience
Using #chemogenetics, we @faurelab.bsky.social show that blocking IPN activation enhances VTA responses and increases nicotine's rewarding effect.
#neuroscience
Reposted by Nicolas Guyon
If you’re a young PI (or senior postdoc) heading to FENS, this one’s for you! It’ll be a lot of fun—and honestly, I can’t think of a better moment in one’s career to have a strong peer network.
📣 Our website is live and registration is NOW OPEN for the Young PI Symposium 2026 - the day prior to FENS Barcelona!
Navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
Check out our program and join us!
Navigate challenges, sharpen leadership skills, make a roadmap together for generations of neuroscientists!
youngpisymposium2026.com
Check out our program and join us!
Young PI Symposium 2026
Visit the post for more.
youngpisymposium2026.com
January 16, 2026 at 12:58 PM
If you’re a young PI (or senior postdoc) heading to FENS, this one’s for you! It’ll be a lot of fun—and honestly, I can’t think of a better moment in one’s career to have a strong peer network.
Reposted by Nicolas Guyon
🗓 The next round of #NCAMH funding is coming soon on 1 Feb 2026!
Discover more about the program & start connecting with research partners for your application!
https://ibro.org/grants/ncamh/
#IBROinAsiaPacific #IBROinUSCanada #IBROinAfrica #IBROinLatAm #IBROinEurope
Wellcome Trust
Discover more about the program & start connecting with research partners for your application!
https://ibro.org/grants/ncamh/
#IBROinAsiaPacific #IBROinUSCanada #IBROinAfrica #IBROinLatAm #IBROinEurope
Wellcome Trust
January 16, 2026 at 2:05 PM
🗓 The next round of #NCAMH funding is coming soon on 1 Feb 2026!
Discover more about the program & start connecting with research partners for your application!
https://ibro.org/grants/ncamh/
#IBROinAsiaPacific #IBROinUSCanada #IBROinAfrica #IBROinLatAm #IBROinEurope
Wellcome Trust
Discover more about the program & start connecting with research partners for your application!
https://ibro.org/grants/ncamh/
#IBROinAsiaPacific #IBROinUSCanada #IBROinAfrica #IBROinLatAm #IBROinEurope
Wellcome Trust
Reposted by Nicolas Guyon
Published in Cell, a new study shows that the immune system’s reaction to the common Epstein-Barr virus can ultimately damage the brain and contribute to multiple sclerosis, from a team @ki.se
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Anoctamin-2-specific T cells link Epstein-Barr virus to multiple sclerosis
Researchers identified anoctamin-2 (ANO2) as a frequent autoimmune target in multiple
sclerosis, with T cell responses against ANO2 occurring in over half of patients.
These ANO2-specific T cells shar...
www.cell.com
January 14, 2026 at 8:54 PM
Published in Cell, a new study shows that the immune system’s reaction to the common Epstein-Barr virus can ultimately damage the brain and contribute to multiple sclerosis, from a team @ki.se
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Reposted by Nicolas Guyon
📣First preprint of the lab📣 Did that really happen?😅
Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...
Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...
Genetic sex of enteric neurons enables ovarian relaxin to gate maternal gut plasticity
Animals must align intestinal plasticity and feeding with reproductive state, yet the checkpoint that gates these adaptations is unknown. Here we show that an ovary-to-enteric-neuron axis gates the on...
www.biorxiv.org
January 11, 2026 at 3:32 PM
📣First preprint of the lab📣 Did that really happen?😅
Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...
Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...
@laurenmac.bsky.social out here repping the lab (and in perfect French!)
@faurelab.bsky.social @espciparispsl.bsky.social @cnrs.fr @psl-univ.bsky.social
@faurelab.bsky.social @espciparispsl.bsky.social @cnrs.fr @psl-univ.bsky.social
@laurenmac.bsky.social, chercheuse en neurosciences au laboratoire Plasticité du cerveau est lauréate du Prix Bernard Bioulac 2025.
👋 @cnrs-paris.bsky.social @espciparispsl.bsky.social @faurelab.bsky.social
www.youtube.com/watch?v=yneN...
👋 @cnrs-paris.bsky.social @espciparispsl.bsky.social @faurelab.bsky.social
www.youtube.com/watch?v=yneN...
Lauren Reynolds, chercheuse en neurosciences | Prix Bernard Bioulac 2025
YouTube video by CNRS - En direct des labos
www.youtube.com
January 9, 2026 at 5:03 PM
@laurenmac.bsky.social out here repping the lab (and in perfect French!)
@faurelab.bsky.social @espciparispsl.bsky.social @cnrs.fr @psl-univ.bsky.social
@faurelab.bsky.social @espciparispsl.bsky.social @cnrs.fr @psl-univ.bsky.social
Reposted by Nicolas Guyon
Very happy for this @ejneuroscience.bsky.social editorial on the importance of diverse research animals in neuroscience. We make the case that embracing a plurality of model organisms enriches the field and accelerates both basic and translational research. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
January 6, 2026 at 7:47 AM
Very happy for this @ejneuroscience.bsky.social editorial on the importance of diverse research animals in neuroscience. We make the case that embracing a plurality of model organisms enriches the field and accelerates both basic and translational research. onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Nicolas Guyon
Indeed. Starting on 1953. Operation Ajax
Maduro is no Mosadegh but CIA and MI6 removed Mosadegh mostly because he had nationalized the Iranian oil industry. The imposed regime change restored control of Iranian oil to US/UK companies
And that clearly led to a democratic and prosperous middle east
Maduro is no Mosadegh but CIA and MI6 removed Mosadegh mostly because he had nationalized the Iranian oil industry. The imposed regime change restored control of Iranian oil to US/UK companies
And that clearly led to a democratic and prosperous middle east
finally, we're living through precedented times
January 4, 2026 at 5:25 PM
Indeed. Starting on 1953. Operation Ajax
Maduro is no Mosadegh but CIA and MI6 removed Mosadegh mostly because he had nationalized the Iranian oil industry. The imposed regime change restored control of Iranian oil to US/UK companies
And that clearly led to a democratic and prosperous middle east
Maduro is no Mosadegh but CIA and MI6 removed Mosadegh mostly because he had nationalized the Iranian oil industry. The imposed regime change restored control of Iranian oil to US/UK companies
And that clearly led to a democratic and prosperous middle east
Reposted by Nicolas Guyon
People are going to try and lure you into debates about whether Maduro was a good guy or not and the thing is, it doesn’t matter for the purposes of discussing whether violent kidnappings and extrajudicial murders by the US government are ok. No, they aren’t! End of convo.
January 3, 2026 at 2:01 PM
People are going to try and lure you into debates about whether Maduro was a good guy or not and the thing is, it doesn’t matter for the purposes of discussing whether violent kidnappings and extrajudicial murders by the US government are ok. No, they aren’t! End of convo.
Reposted by Nicolas Guyon
Is the 5-HT2A Receptor the Key to Psychedelic Effects?
YouTube video by Xylo Bio
www.youtube.com
December 23, 2025 at 6:47 PM
Reposted by Nicolas Guyon
“Basic neuroscience hasn’t produced new drugs.” 💊
Not true - zuranolone (PPD), suzetrigine (pain), gepants (migraine), and more... were born out of a long arc of studies in the lab.
I wrote a Perspective on why this matters. @thetransmitter.bsky.social
www.thetransmitter.org/drug-develop...
Not true - zuranolone (PPD), suzetrigine (pain), gepants (migraine), and more... were born out of a long arc of studies in the lab.
I wrote a Perspective on why this matters. @thetransmitter.bsky.social
www.thetransmitter.org/drug-develop...
How basic neuroscience has paved the path to new drugs
A growing list of medications—such as zuranolone for postpartum depression, suzetrigine for pain, and the gepants class of migraine medicines—exist because of insights from basic research.
www.thetransmitter.org
December 15, 2025 at 3:15 PM
“Basic neuroscience hasn’t produced new drugs.” 💊
Not true - zuranolone (PPD), suzetrigine (pain), gepants (migraine), and more... were born out of a long arc of studies in the lab.
I wrote a Perspective on why this matters. @thetransmitter.bsky.social
www.thetransmitter.org/drug-develop...
Not true - zuranolone (PPD), suzetrigine (pain), gepants (migraine), and more... were born out of a long arc of studies in the lab.
I wrote a Perspective on why this matters. @thetransmitter.bsky.social
www.thetransmitter.org/drug-develop...
Reposted by Nicolas Guyon
We used rabies virus 👾 to map how #psilocybin modifies long-range circuits 🧠, revealing network-specific reorganization that we didn’t expect.
The full study is now online at Cell. @cp-cell.bsky.social
Paper 👉 www.cell.com/cell/fulltex...
Thread for a synopsis 👉
bsky.app/profile/alex...
The full study is now online at Cell. @cp-cell.bsky.social
Paper 👉 www.cell.com/cell/fulltex...
Thread for a synopsis 👉
bsky.app/profile/alex...
December 5, 2025 at 4:29 PM
We used rabies virus 👾 to map how #psilocybin modifies long-range circuits 🧠, revealing network-specific reorganization that we didn’t expect.
The full study is now online at Cell. @cp-cell.bsky.social
Paper 👉 www.cell.com/cell/fulltex...
Thread for a synopsis 👉
bsky.app/profile/alex...
The full study is now online at Cell. @cp-cell.bsky.social
Paper 👉 www.cell.com/cell/fulltex...
Thread for a synopsis 👉
bsky.app/profile/alex...
Reposted by Nicolas Guyon
Cool preprint from the lab of Raouf Issa at ESPCI in Paris with a small contribution from our lab at @ijmonod.bsky.social
Padmanabhan et al found that a specific set of Drosophila dopamine neurons, which is already active in embryos and stays functionally important for locomotion throughout life.
Padmanabhan et al found that a specific set of Drosophila dopamine neurons, which is already active in embryos and stays functionally important for locomotion throughout life.
Lifelong maintenance of locomotion by embryonically active dopamine neurons https://www.biorxiv.org/content/10.64898/2025.11.28.691140v1
December 3, 2025 at 9:43 AM
Cool preprint from the lab of Raouf Issa at ESPCI in Paris with a small contribution from our lab at @ijmonod.bsky.social
Padmanabhan et al found that a specific set of Drosophila dopamine neurons, which is already active in embryos and stays functionally important for locomotion throughout life.
Padmanabhan et al found that a specific set of Drosophila dopamine neurons, which is already active in embryos and stays functionally important for locomotion throughout life.
Reposted by Nicolas Guyon
Apply for a PhD in Paris!! A project to come and work with me and my team at the GutSense lab included in the list! 🪰🧠⛽
📚 The international DIM C-BRAINS PhD program is back!
Up for grabs: 7 fully funded, 3-year doctoral contracts in the Île-de-France region, 3 of which will be hosted by Paris Brain Institute.
📆 Application deadline: February 1, 2026.
👉 Find out more: parisbraininstitute.org/dim-c-brains...
Up for grabs: 7 fully funded, 3-year doctoral contracts in the Île-de-France region, 3 of which will be hosted by Paris Brain Institute.
📆 Application deadline: February 1, 2026.
👉 Find out more: parisbraininstitute.org/dim-c-brains...
The DIM C-BRAINS international PhD program opens its 2026 call for applications. | Paris Brain Institute
The international DIM C-BRAINS PhD program is back. Up for grabs: 7 fully funded, 3-year doctoral contracts in the Île-de-France region, 3 of which will be hosted by the Institut du Cerveau. Applicati...
parisbraininstitute.org
December 5, 2025 at 5:13 PM
Apply for a PhD in Paris!! A project to come and work with me and my team at the GutSense lab included in the list! 🪰🧠⛽
Reposted by Nicolas Guyon
Tired of looking at obscure headstage pinouts to figure out which channel is which? 😵
We’ve launched the 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗠𝗮𝗽𝘀 𝗱𝗼𝗰𝘀 to save you time! ⏱️ Now you can easily picture the channel maps of all headstages and connections to compatible adapters and EIBs designed by us.
#OpenEphys
We’ve launched the 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗠𝗮𝗽𝘀 𝗱𝗼𝗰𝘀 to save you time! ⏱️ Now you can easily picture the channel maps of all headstages and connections to compatible adapters and EIBs designed by us.
#OpenEphys
Home — Channel Maps
Here you can find the specifications and channel mapping for all the headstages, adapters and EIBs produced by Open Ephys that are available through the Open Ephys Store.
open-ephys.github.io
November 28, 2025 at 2:03 PM
Tired of looking at obscure headstage pinouts to figure out which channel is which? 😵
We’ve launched the 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗠𝗮𝗽𝘀 𝗱𝗼𝗰𝘀 to save you time! ⏱️ Now you can easily picture the channel maps of all headstages and connections to compatible adapters and EIBs designed by us.
#OpenEphys
We’ve launched the 𝗖𝗵𝗮𝗻𝗻𝗲𝗹 𝗠𝗮𝗽𝘀 𝗱𝗼𝗰𝘀 to save you time! ⏱️ Now you can easily picture the channel maps of all headstages and connections to compatible adapters and EIBs designed by us.
#OpenEphys
And we have a new doctor in the @faurelab.bsky.social : Maria Ciscato!
Auguri per il tuo dottorato!
@espciparispsl.bsky.social @psl-univ.bsky.social
Auguri per il tuo dottorato!
@espciparispsl.bsky.social @psl-univ.bsky.social
November 17, 2025 at 3:49 PM
And we have a new doctor in the @faurelab.bsky.social : Maria Ciscato!
Auguri per il tuo dottorato!
@espciparispsl.bsky.social @psl-univ.bsky.social
Auguri per il tuo dottorato!
@espciparispsl.bsky.social @psl-univ.bsky.social
Happy to share our new protocol in @cp-starprotocols.bsky.social: CATCH—Covalent Anchoring of Tethered Ligands to Chemogenetic Handles!
This method enables precise, long-lasting, and pharmacologically specific inhibition of brain receptors in vivo.
👉 www.sciencedirect.com/science/arti...
This method enables precise, long-lasting, and pharmacologically specific inhibition of brain receptors in vivo.
👉 www.sciencedirect.com/science/arti...
Covalent anchoring of tethered ligands to chemogenetic handles for targeted in vivo neuropharmacology
Covalent anchoring of tethered ligands to chemogenetic handles (CATCH) is a chemogenetic approach that enables sustained, localized, and pharmacologic…
www.sciencedirect.com
November 15, 2025 at 11:29 AM
Happy to share our new protocol in @cp-starprotocols.bsky.social: CATCH—Covalent Anchoring of Tethered Ligands to Chemogenetic Handles!
This method enables precise, long-lasting, and pharmacologically specific inhibition of brain receptors in vivo.
👉 www.sciencedirect.com/science/arti...
This method enables precise, long-lasting, and pharmacologically specific inhibition of brain receptors in vivo.
👉 www.sciencedirect.com/science/arti...
Reposted by Nicolas Guyon
The first Pan-African neuroscience journal, the African Brain Journal, prepares to launch.
By Lauren Schenkman
#neuroskyence
www.thetransmitter.org/publishing/f...
By Lauren Schenkman
#neuroskyence
www.thetransmitter.org/publishing/f...
First Pan-African neuroscience journal gets ready to launch
The new journal hopes to give African neuroscience research much-needed international visibility.
www.thetransmitter.org
October 28, 2025 at 3:07 PM
The first Pan-African neuroscience journal, the African Brain Journal, prepares to launch.
By Lauren Schenkman
#neuroskyence
www.thetransmitter.org/publishing/f...
By Lauren Schenkman
#neuroskyence
www.thetransmitter.org/publishing/f...
Reposted by Nicolas Guyon
Friday, November 13, 2015, Paris fell victim to the deadliest terrorist attacks ever carried out in France. Ten years later, to the day, Paris remembers and honors their memory.
November 13, 2025 at 7:01 AM
Friday, November 13, 2015, Paris fell victim to the deadliest terrorist attacks ever carried out in France. Ten years later, to the day, Paris remembers and honors their memory.
Reposted by Nicolas Guyon
New #PhD ad alert!
Interested in wild #bee #cognition and #brains in different #bumblebees? Want to live in #Newcastle and the beautiful north-east of England?
Check out this project with me, @lenariab.bsky.social and Sarah Scott. Contact me for further information.
iapetus.ac.uk/studentships...
Interested in wild #bee #cognition and #brains in different #bumblebees? Want to live in #Newcastle and the beautiful north-east of England?
Check out this project with me, @lenariab.bsky.social and Sarah Scott. Contact me for further information.
iapetus.ac.uk/studentships...
The cognitive ecology of wild bumblebees
iapetus.ac.uk
October 28, 2025 at 11:22 AM
New #PhD ad alert!
Interested in wild #bee #cognition and #brains in different #bumblebees? Want to live in #Newcastle and the beautiful north-east of England?
Check out this project with me, @lenariab.bsky.social and Sarah Scott. Contact me for further information.
iapetus.ac.uk/studentships...
Interested in wild #bee #cognition and #brains in different #bumblebees? Want to live in #Newcastle and the beautiful north-east of England?
Check out this project with me, @lenariab.bsky.social and Sarah Scott. Contact me for further information.
iapetus.ac.uk/studentships...
Reposted by Nicolas Guyon
On this week’s cover of The Lancet, a new letter: “Gaza’s healthocide: medical societies must not stay silent”.
Read the letter and more in our latest issue: tinyurl.com/5n85x448
Read the letter and more in our latest issue: tinyurl.com/5n85x448
![Cover of The Lancet's Oct 4, 2025 issue. Cover quote reads: "Most medical and surgical societies worldwide have remained silent or issued vague statements about Gaza's healthocide [...] Staying silent while pretending to be neutral is, in effect, a form of complicity."](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:ypu6bwefbbzhcvojdj7mz657/bafkreih3gz5fes4mk4pbviqqus2zo2bqyrx3cgbgqb7xg2skvpvl52tj5i@jpeg)
October 6, 2025 at 5:28 AM
On this week’s cover of The Lancet, a new letter: “Gaza’s healthocide: medical societies must not stay silent”.
Read the letter and more in our latest issue: tinyurl.com/5n85x448
Read the letter and more in our latest issue: tinyurl.com/5n85x448
Reposted by Nicolas Guyon
Trying to log into Eduroam
September 29, 2025 at 12:56 PM
Trying to log into Eduroam
Reposted by Nicolas Guyon
1/
🚨 New preprint! 🚨
Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇
📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩
#neuroskyence
🚨 New preprint! 🚨
Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇
📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩
#neuroskyence
September 17, 2025 at 7:33 PM
1/
🚨 New preprint! 🚨
Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇
📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩
#neuroskyence
🚨 New preprint! 🚨
Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇
📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩
#neuroskyence