Nicolas Guyon
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nicolasguyon.bsky.social
Nicolas Guyon
@nicolasguyon.bsky.social
Vetenskapsrådet Postdoctoral Fellow at @espciparispsl.bsky.social‬.
ex PhD in neuroscience in Carlén Lab at @ki.se.

➡️ https://faurelab.cnrs.fr/?page_id=857
Pinned
Super happy to see our new study, on how the interpeduncular nucleus (IPN) regulates nicotine reward, out today in @cp-neuron.bsky.social!

Using #chemogenetics, we @faurelab.bsky.social show that blocking IPN activation enhances VTA responses and increases nicotine's rewarding effect.
#neuroscience
The interpeduncular nucleus blunts the rewarding effect of nicotine
Nicotine activates the dopamine reward system to promote consumption and addiction, but the brain has a natural brake to counteract it. Jehl, Ciscato, Vicq, Guyon, et al. identified the interpeduncula...
www.cell.com
Happy to share our new protocol in @cp-starprotocols.bsky.social: CATCH—Covalent Anchoring of Tethered Ligands to Chemogenetic Handles!

This method enables precise, long-lasting, and pharmacologically specific inhibition of brain receptors in vivo.

👉 www.sciencedirect.com/science/arti...
Covalent anchoring of tethered ligands to chemogenetic handles for targeted in vivo neuropharmacology
Covalent anchoring of tethered ligands to chemogenetic handles (CATCH) is a chemogenetic approach that enables sustained, localized, and pharmacologic…
www.sciencedirect.com
November 15, 2025 at 11:29 AM
Reposted by Nicolas Guyon
The first Pan-African neuroscience journal, the African Brain Journal, prepares to launch.

By Lauren Schenkman

#neuroskyence

www.thetransmitter.org/publishing/f...
First Pan-African neuroscience journal gets ready to launch
The new journal hopes to give African neuroscience research much-needed international visibility.
www.thetransmitter.org
October 28, 2025 at 3:07 PM
Reposted by Nicolas Guyon
Friday, November 13, 2015, Paris fell victim to the deadliest terrorist attacks ever carried out in France. Ten years later, to the day, Paris remembers and honors their memory.
November 13, 2025 at 7:01 AM
Reposted by Nicolas Guyon
New #PhD ad alert!
Interested in wild #bee #cognition and #brains in different #bumblebees? Want to live in #Newcastle and the beautiful north-east of England?

Check out this project with me, @lenariab.bsky.social and Sarah Scott. Contact me for further information.

iapetus.ac.uk/studentships...
The cognitive ecology of wild bumblebees
iapetus.ac.uk
October 28, 2025 at 11:22 AM
Reposted by Nicolas Guyon
On this week’s cover of The Lancet, a new letter: “Gaza’s healthocide: medical societies must not stay silent”.

Read the letter and more in our latest issue: tinyurl.com/5n85x448
October 6, 2025 at 5:28 AM
Reposted by Nicolas Guyon
Trying to log into Eduroam
September 29, 2025 at 12:56 PM
Reposted by Nicolas Guyon
1/
🚨 New preprint! 🚨

Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇

📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩

#neuroskyence
September 17, 2025 at 7:33 PM
September 17, 2025 at 12:08 PM
Reposted by Nicolas Guyon
Thrilled to share that our work is now published in Science! ✨

We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭

www.science.org/doi/10.1126/...

🧵1/
September 11, 2025 at 8:14 PM
Reposted by Nicolas Guyon
We are still accepting applications for the #postdoc opportunity in the lab 🕵‍♀️ 🧠

More details 👇
Postdoctoral position: lnkd.in/g4TkRxpM
Research directions: lnkd.in/eV2iMKGf
Our team and philosophy: lnkd.in/eh3nnNgq

August 25, 2025 at 4:32 AM
Reposted by Nicolas Guyon
Only one more week to apply to do a postdoc with our group and this of
@thomasdwkim.bsky.social
@ncmbm.bsky.social
@nordicembl.bsky.social
! If you are interested, contact us or apply directly to the add. Please RT.
www.jobbnorge.no/en/available...
August 7, 2025 at 6:30 AM
Reposted by Nicolas Guyon
Today, our article "The entities enabling scientific fraud at scale are large, resilient, and growing rapidly" is finally published in PNAS. I hope that it proves to be a wake-up-call for the whole scientific community.

reeserichardson.blog/2025/08/04/a...
A do-or-die moment for the scientific enterprise
Reflecting on our paper “The entities enabling scientific fraud at scale are large, resilient, and growing rapidly”
reeserichardson.blog
August 4, 2025 at 8:47 PM
Reposted by Nicolas Guyon
#PressRelease 🗞️ Nanobodies were recently generated from llama antibodies to target a key brain receptor involved in schizophrenia 🧬 🦙

👉 www.cnrs.fr/en/press/lla...
July 24, 2025 at 8:30 AM
Reposted by Nicolas Guyon
"L'illusion de la main en caoutchouc" (où l'on a l'impression de posséder une fausse main quand on la voit placée dans le prolongement de son bras et qu'elle est stimulée tactilement) est une expérience importante pour étudier l'attribution de propriété corporelle... adaptée chez la pieuvre 😍
July 22, 2025 at 6:00 AM
Reposted by Nicolas Guyon
❗ Interested in quantifiying and displaying histological data? Check out our recent python package operating downstream of histological alignement and segmentation pipelines (eg ABBA, QuPath) to calculate and illustrate various metrics, including exquisite tutorials!
joss.theoj.org/papers/10.21...
cuisto: A Python package to quantify neurohistological data from QuPath and ABBA
Le Goc et al., (2025). cuisto: A Python package to quantify neurohistological data from QuPath and ABBA. Journal of Open Source Software, 10(111), 7906, https://doi.org/10.21105/joss.07906
joss.theoj.org
July 18, 2025 at 11:34 AM
Reposted by Nicolas Guyon
Alcool et nicotine : un même circuit cérébral à l’origine de la récompense et de l’anxiété

👋 @cnrs-paris.bsky.social @espciparispsl.bsky.social
✍️ @faurelab.bsky.social & Fabio Marti
👉 Lire l'article dans buff.ly/vE1j6LP
buff.ly/fD5DOxu
July 10, 2025 at 5:00 AM
Reposted by Nicolas Guyon
Data reuse represents an opportunity to accelerate science, reduce costs and increase the value of investments. But to date, the field hasn't placed equal emphasis on the reuse side of the data-sharing equation, writes @bendichter.com

#neuroskyence

www.thetransmitter.org/open-neurosc...
Data reuse represents an opportunity to accelerate the pace of science, reduce costs and increase the value of our collective research investments.
Data reuse represents an opportunity to accelerate the pace of science, reduce costs and increase the value of our collective research investments. New tools that make open data easier to use—and new…
www.thetransmitter.org
July 7, 2025 at 1:47 PM
Check out our latest research on the neural mechanisms of nicotine (and alcohol) feedback in dopamine circuits, just published in @natcomms.nature.com!
July 5, 2025 at 7:02 PM
Reposted by Nicolas Guyon
July 5, 2025 at 5:01 PM
Reposted by Nicolas Guyon
Our work on the role of the interpeduncular nucleus in nicotine reward ( www.cell.com/neuron/abstr... ) is featured in a Neuron Preview ! Brandon J Henderson highlights how a new regulatory circuit controlling nicotine reinforcement has been uncovered. www.cell.com/neuron/abstr...
Slowing the drive: A new regulatory break for nicotine reward-related behaviors
In this issue of Neuron, Jehl et al. developed a “suicide” antagonist to demonstrate that the interpeduncular nucleus acts as a regulatory controller of nicotine reward-related behavior through connec...
www.cell.com
June 19, 2025 at 1:02 PM
Reposted by Nicolas Guyon
We need your help!!! 🧠🧪💤

If you are human, you fall asleep at least once a day! What happens in your mind then?

Scientists know actually very little about this private moment.

We propose a 20-min survey to get as much data as possible!

Here is the link:
redcap.link/DriftingMinds
June 19, 2025 at 2:43 PM
Reposted by Nicolas Guyon
Two postdoc positions in the lab within the ERC Synergy project "Chronology" in collaboration with S. Ostojic, M. Jazayeri and V. van Wassenhove @virginievanw.bsky.social . Two focuses: sound sequences representations across the brain & novel all-optical technology. Contact: brice.bathellier@cnrs.fr
June 15, 2025 at 8:20 AM
The other shoe finally dropped. We were notified this morning that our NIH funding for our work on photopharmacology tools has been cut.

We’ll keep going with or without them 🤷‍♂️
June 13, 2025 at 12:52 PM
Reposted by Nicolas Guyon
#NewsletterLaunch!
📢Introducing Transcript- our new quarterly newsletter featuring stories of discoveries, ideas & the people bringing them to life at NCBS!

📖Read here: bit.ly/transcript_n...

📩Subscribe to get our Newsletter delivered directly to your inbox: bit.ly/4kEQxvh
June 12, 2025 at 5:01 AM