Melike Eren
@neurowithmelike.bsky.social
MSc. Neuroscience &MSc.Physiotherapy| Just a researcher, microglia lover |I hope to become a PhD student in neuroscience | Neuroscience, Anatomy & Exercise Physiology
Reposted by Melike Eren
Imposter syndrome is strongly linked to these two types of perfectionism
Imposter syndrome is strongly linked to these two types of perfectionism
New psychological research reveals that imposter phenomenon is related to rigid and self-critical tendencies. However, perfectionists who hold grandiose views of themselves appear buffered against these feelings of self-doubt.
www.psypost.org
January 25, 2026 at 11:26 AM
Imposter syndrome is strongly linked to these two types of perfectionism
Reposted by Melike Eren
This is Alex Pretti.
This morning he was murdered by ICE. Six ICE agents held him down and shot him at point blank range. Alex was a nurse and researcher at the VA.
Our thoughts are with his loved ones and we stand united in action calling for the abolishment of ICE.
#ScientistsAgainstICE
This morning he was murdered by ICE. Six ICE agents held him down and shot him at point blank range. Alex was a nurse and researcher at the VA.
Our thoughts are with his loved ones and we stand united in action calling for the abolishment of ICE.
#ScientistsAgainstICE
January 24, 2026 at 8:03 PM
This is Alex Pretti.
This morning he was murdered by ICE. Six ICE agents held him down and shot him at point blank range. Alex was a nurse and researcher at the VA.
Our thoughts are with his loved ones and we stand united in action calling for the abolishment of ICE.
#ScientistsAgainstICE
This morning he was murdered by ICE. Six ICE agents held him down and shot him at point blank range. Alex was a nurse and researcher at the VA.
Our thoughts are with his loved ones and we stand united in action calling for the abolishment of ICE.
#ScientistsAgainstICE
Reposted by Melike Eren
Alex Pretti was a scientist.
Alex Pretti, the man shot by ICE in Minneapolis, appears to have previously worked with the federal government at the VA.
There is a photo of him on the VA website, where he’s cited as part of a medical research team.
www.vacsp.research.va.gov/CSP_2004/CSP...
There is a photo of him on the VA website, where he’s cited as part of a medical research team.
www.vacsp.research.va.gov/CSP_2004/CSP...
January 24, 2026 at 7:40 PM
Alex Pretti was a scientist.
Reposted by Melike Eren
New Article! Transsynaptic tracing techniques to interrogate neuronal connectivity of glioblastomas
Transsynaptic tracing techniques to interrogate neuronal connectivity of glioblastomas
Nature Protocols, Published online: 21 January 2026; doi:10.1038/s41596-025-01287-wThis protocol details transsynaptic tracing approaches using retrograde and anterograde viral tracers to map and manipulate neuron–tumor circuits in xenografts, brain organoid models and co-cultures.
dlvr.it
January 21, 2026 at 3:01 PM
New Article! Transsynaptic tracing techniques to interrogate neuronal connectivity of glioblastomas
Reposted by Melike Eren
Now online! Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder
Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder
This study describes the cell-type-specific lysosomal proteome across the major brain cell types and identifies SLC45A1 as a neuron-specific lysosomal sugar exporter linked to lysosomal storage disease.
dlvr.it
January 22, 2026 at 3:59 PM
Now online! Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder
Reposted by Melike Eren
Spatially resolved lipids in a mouse brain model of globoid cell leukodystrophy via IR-MALDESI MSI and parallel reaction monitoring MSI #ABC link.springer.com/article/10.1...
Spatially resolved lipids in a mouse brain model of globoid cell leukodystrophy via IR-MALDESI MSI and parallel reaction monitoring MSI - Analytical and Bioanalytical Chemistry
Globoid cell leukodystrophy (GLD) is a genetic neurodegenerative disease caused by mutations in galactosylceramide β-galactosidase (GALC) that results in the accumulation of the cytotoxic sphingolipid...
link.springer.com
January 23, 2026 at 9:05 PM
Spatially resolved lipids in a mouse brain model of globoid cell leukodystrophy via IR-MALDESI MSI and parallel reaction monitoring MSI #ABC link.springer.com/article/10.1...
Reposted by Melike Eren
Diffuse midline glioma tumor cells communicate with microglia through IGSF11-VISTA signaling, a tragetable pathway to promote tumor control
@cp-cancercell.bsky.social @radboudumc.bsky.social @rcollot.bsky.social
www.cell.com/cancer-cell/...
@cp-cancercell.bsky.social @radboudumc.bsky.social @rcollot.bsky.social
www.cell.com/cancer-cell/...
January 23, 2026 at 5:50 PM
Diffuse midline glioma tumor cells communicate with microglia through IGSF11-VISTA signaling, a tragetable pathway to promote tumor control
@cp-cancercell.bsky.social @radboudumc.bsky.social @rcollot.bsky.social
www.cell.com/cancer-cell/...
@cp-cancercell.bsky.social @radboudumc.bsky.social @rcollot.bsky.social
www.cell.com/cancer-cell/...
Reposted by Melike Eren
We put CellBouncer to the test with a challenging demultiplexing problem of assigning 24 hominid tetraploid composite cell lines generated by Bryan Pavlovic to both individuals-of-origin and identifying the mitochondrial haplotypes present.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
March 24, 2025 at 10:07 PM
We put CellBouncer to the test with a challenging demultiplexing problem of assigning 24 hominid tetraploid composite cell lines generated by Bryan Pavlovic to both individuals-of-origin and identifying the mitochondrial haplotypes present.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Melike Eren
EMBOMtg Paris May 6-9
@aydoganlab.bsky.social @jamesbriscoe.bsky.social @brunetlab.bsky.social @ebisuyamiki.bsky.social @mwdorr.bsky.social @beyerlab.bsky.social @franckp.bsky.social @janereznick.bsky.social @olmedo-lab.bsky.social @perez-carrasco.bsky.social
meetings.embo.org/event/25-dev...
@aydoganlab.bsky.social @jamesbriscoe.bsky.social @brunetlab.bsky.social @ebisuyamiki.bsky.social @mwdorr.bsky.social @beyerlab.bsky.social @franckp.bsky.social @janereznick.bsky.social @olmedo-lab.bsky.social @perez-carrasco.bsky.social
meetings.embo.org/event/25-dev...
Developmental timing across species: From mechanisms to evolutionary insights
Like choreography, development consists of a highly ordered suite of steps and transitions. Modifying developmental tempo can affect final size and composition of tissues, as well as their plasticity…
meetings.embo.org
March 29, 2025 at 3:00 PM
Reposted by Melike Eren
Excited to share @rbrianroome.bsky.social ‘s beautiful paper on development of the dorsal horn of the mouse spinal cord @science.org
This is how the anatomical organization and cell types that process pain, touch, body position and more are laid down.
www.science.org/doi/10.1126/...
This is how the anatomical organization and cell types that process pain, touch, body position and more are laid down.
www.science.org/doi/10.1126/...
Ontogeny of the spinal cord dorsal horn
The dorsal horn of the mammalian spinal cord is organized into laminae where each layer is populated by different neuron types, has distinctive circuit connections, and plays specialized roles in beha...
www.science.org
January 8, 2026 at 7:59 PM
Excited to share @rbrianroome.bsky.social ‘s beautiful paper on development of the dorsal horn of the mouse spinal cord @science.org
This is how the anatomical organization and cell types that process pain, touch, body position and more are laid down.
www.science.org/doi/10.1126/...
This is how the anatomical organization and cell types that process pain, touch, body position and more are laid down.
www.science.org/doi/10.1126/...
Reposted by Melike Eren
1/ Our new study, led by Jingwen Ding, examines the role of transcription factors during human neurogenesis to identify gene regulatory networks influencing cell fate, maturation, and subtype specification
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Dissecting gene regulatory networks governing human cortical cell fate - Nature
Systematic screening of transcription factors reveals conserved mechanisms governing cortical radial glia lineage progression across primates and provides a framework for functional dissecti...
www.nature.com
January 23, 2026 at 1:16 AM
1/ Our new study, led by Jingwen Ding, examines the role of transcription factors during human neurogenesis to identify gene regulatory networks influencing cell fate, maturation, and subtype specification
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Melike Eren
I think I'll give up on the idea of doing a PhD and find myself a new path.
January 22, 2026 at 10:24 AM
I think I'll give up on the idea of doing a PhD and find myself a new path.
What fascinates me about pregnancy in MS is its ability to transiently reprogram inflammation. This effect can't be explained by hormones alone; neuroimmune signals such as GDF15 appear to play central role. The key question is why this protection collapses postpartum.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
A GDF-15–GFRAL axis controls autoimmune T cell responses during neuroinflammation - Nature Immunology
Here the authors show that endogenous or therapeutically delivered GDF-15 activates brainstem neurons that trigger splenic β-adrenergic signaling. This, in turn, suppresses autoreactive T cells and re...
www.nature.com
January 22, 2026 at 9:44 AM
What fascinates me about pregnancy in MS is its ability to transiently reprogram inflammation. This effect can't be explained by hormones alone; neuroimmune signals such as GDF15 appear to play central role. The key question is why this protection collapses postpartum.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Melike Eren
Our new paper is out in @natmed.nature.com 😱! A thread:
Can our thoughts and feelings directly affect our physical well-being? Our pre-registered, double-blind RCT investigated this by testing if modulating the brain's reward system could enhance immune responses to vaccination.
Can our thoughts and feelings directly affect our physical well-being? Our pre-registered, double-blind RCT investigated this by testing if modulating the brain's reward system could enhance immune responses to vaccination.
January 21, 2026 at 5:55 PM
Our new paper is out in @natmed.nature.com 😱! A thread:
Can our thoughts and feelings directly affect our physical well-being? Our pre-registered, double-blind RCT investigated this by testing if modulating the brain's reward system could enhance immune responses to vaccination.
Can our thoughts and feelings directly affect our physical well-being? Our pre-registered, double-blind RCT investigated this by testing if modulating the brain's reward system could enhance immune responses to vaccination.
Reposted by Melike Eren
If you’ve hatched a New Year plan to move abroad, improve your presentations or chase happiness as a 20-something researcher, you’ll find advice aplenty in these books.
go.nature.com/3NnF1bG
go.nature.com/3NnF1bG
Nine books to help shape your science career in 2026
If you’ve hatched a New Year plan to move abroad, improve your presentations or chase happiness as a 20-something researcher, you’ll find advice aplenty in these books.
go.nature.com
January 2, 2026 at 2:00 PM
If you’ve hatched a New Year plan to move abroad, improve your presentations or chase happiness as a 20-something researcher, you’ll find advice aplenty in these books.
go.nature.com/3NnF1bG
go.nature.com/3NnF1bG
Reposted by Melike Eren
Beyond thrilled to share my PhD work out today in @natcellbio.nature.com , uncovering a nanoscale acidic environment around lysosomes that controls their mobility through proton signaling.🥳🥳🥳
Great thanks to my advisors and excellent peers for helping me！
www.nature.com/articles/s41...
Great thanks to my advisors and excellent peers for helping me！
www.nature.com/articles/s41...
DNA nanodevices detect an acidic nanolayer on the lysosomal surface - Nature Cell Biology
Tan and colleagues develop DNA nanodevices to detect the pH of the lysosomal outer surface, observing an acidic layer generated by TMEM175 that regulates lysosome positioning in response to changes in...
www.nature.com
January 21, 2026 at 11:27 AM
Beyond thrilled to share my PhD work out today in @natcellbio.nature.com , uncovering a nanoscale acidic environment around lysosomes that controls their mobility through proton signaling.🥳🥳🥳
Great thanks to my advisors and excellent peers for helping me！
www.nature.com/articles/s41...
Great thanks to my advisors and excellent peers for helping me！
www.nature.com/articles/s41...
journals.lww.com
January 21, 2026 at 3:19 PM
Reposted by Melike Eren
New paper out: Neural correlates of #social affect and social cognition as risk markers of #bipolardisorder
Big congrats to Dahna Choi et al. 🎉
@tudresden.bsky.social @kanskelab.bsky.social @dgps.bsky.social @biodgps-dgpa.bsky.social
doi.org/10.1192/bjp....
Big congrats to Dahna Choi et al. 🎉
@tudresden.bsky.social @kanskelab.bsky.social @dgps.bsky.social @biodgps-dgpa.bsky.social
doi.org/10.1192/bjp....
January 21, 2026 at 1:49 PM
New paper out: Neural correlates of #social affect and social cognition as risk markers of #bipolardisorder
Big congrats to Dahna Choi et al. 🎉
@tudresden.bsky.social @kanskelab.bsky.social @dgps.bsky.social @biodgps-dgpa.bsky.social
doi.org/10.1192/bjp....
Big congrats to Dahna Choi et al. 🎉
@tudresden.bsky.social @kanskelab.bsky.social @dgps.bsky.social @biodgps-dgpa.bsky.social
doi.org/10.1192/bjp....
Throughout my life, I have studied at the best state schools in my country, and I am grateful for this education. However, because I only received education in sci&math; stem. I am not good at social sciences. As a scientist(c), I realised that reading about social sci specifically philosophy
January 21, 2026 at 1:36 PM
Throughout my life, I have studied at the best state schools in my country, and I am grateful for this education. However, because I only received education in sci&math; stem. I am not good at social sciences. As a scientist(c), I realised that reading about social sci specifically philosophy
Reposted by Melike Eren
If you are a neuroscience PhD student outside of Europe, and want to spend some time here, this is a fantastic opportunity!
🌍 Applications are open! The IBRO Exchange Fellowships give early career #neuroscientists to conduct lab visits with several expenses covered during the exchange.
🗓 Apply by 15 Apr: https://ibro.org/grant/exchange-fellowships/
#grant #IBROinAsiaPacific #IBROinUSCanada #IBROinAfrica #IBROinLatAm
🗓 Apply by 15 Apr: https://ibro.org/grant/exchange-fellowships/
#grant #IBROinAsiaPacific #IBROinUSCanada #IBROinAfrica #IBROinLatAm
January 15, 2026 at 12:11 PM
If you are a neuroscience PhD student outside of Europe, and want to spend some time here, this is a fantastic opportunity!
Reposted by Melike Eren
Needless bureaucracy and “bullshit jobs” are preventing academics from fulfilling their core creative responsibilities and making clinical research an “impossible task”, a leading neuroscientist has warned. @patrickjack.bsky.social reports
#AcademicSky
#AcademicSky
‘Mountain of small things’ killing academia, warns Oxford scholar
Overly cautious institutions pushing ‘bullshit jobs’ on their staff ‘destroying academia from within’, says neuroscientist
www.timeshighereducation.com
April 10, 2025 at 7:41 AM
Needless bureaucracy and “bullshit jobs” are preventing academics from fulfilling their core creative responsibilities and making clinical research an “impossible task”, a leading neuroscientist has warned. @patrickjack.bsky.social reports
#AcademicSky
#AcademicSky
Reposted by Melike Eren
Call for Symposium Proposals NOW OPEN | #Glia2027
Submit proposals for Symposia, Special Trainee and Technical Symposia covering all aspects of glial biology (CNS & PNS).
Deadline: 8 April 2026.
Details: www.glia-meeting.eu
#GlialCells #Astrocytes #Oligodendrocytes #Microglia #SchwannCells
Submit proposals for Symposia, Special Trainee and Technical Symposia covering all aspects of glial biology (CNS & PNS).
Deadline: 8 April 2026.
Details: www.glia-meeting.eu
#GlialCells #Astrocytes #Oligodendrocytes #Microglia #SchwannCells
January 20, 2026 at 9:38 AM
Call for Symposium Proposals NOW OPEN | #Glia2027
Submit proposals for Symposia, Special Trainee and Technical Symposia covering all aspects of glial biology (CNS & PNS).
Deadline: 8 April 2026.
Details: www.glia-meeting.eu
#GlialCells #Astrocytes #Oligodendrocytes #Microglia #SchwannCells
Submit proposals for Symposia, Special Trainee and Technical Symposia covering all aspects of glial biology (CNS & PNS).
Deadline: 8 April 2026.
Details: www.glia-meeting.eu
#GlialCells #Astrocytes #Oligodendrocytes #Microglia #SchwannCells