Natalie Turner
@natalieturnerau.bsky.social
Postdoc @ Scripps Research - Yates lab | Extracellular Vesicles | Mass Spectrometry | Proteomics | Bioinformatics. Multi-omics enthusiast. Here to talk science 👩🏻🔬. 🇦🇺 🇺🇸 🇬🇧 .
Very thorough and thought-provoking review on #extracellularvesicles - clinical applications in cancer diagnostics, vaccines, and drug delivery systems, by Greening et al.
Published in Nature Reviews Clinical Oncology:
www.nature.com/articles/s41...
Published in Nature Reviews Clinical Oncology:
www.nature.com/articles/s41...
Clinical relevance of extracellular vesicles in cancer — therapeutic and diagnostic potential - Nature Reviews Clinical Oncology
Extracellular vesicles (EVs), a diverse range of membrane-delimited particles, have multiple cellular functions and, when released by cancer cells, can promote tumour growth and metastatic dissemination. The authors of this Review describe advances in the development of EVs as biomarkers and cancer therapeutics, focusing on clinical translation of EVs into diagnostic and therapeutic clinical tools.
www.nature.com
October 13, 2025 at 1:59 AM
Very thorough and thought-provoking review on #extracellularvesicles - clinical applications in cancer diagnostics, vaccines, and drug delivery systems, by Greening et al.
Published in Nature Reviews Clinical Oncology:
www.nature.com/articles/s41...
Published in Nature Reviews Clinical Oncology:
www.nature.com/articles/s41...
Reposted by Natalie Turner
Obesity may directly drive Alzheimer’s disease. Scientists discovered that tiny messengers released by fat tissue, called extracellular vesicles, can carry harmful signals that accelerate the buildup of amyloid-β plaques in the brain.
www.sciencedaily.com/releases/202...
www.sciencedaily.com/releases/202...
Fat may secretly fuel Alzheimer’s, new research finds
New research from Houston Methodist reveals how obesity may directly drive Alzheimer’s disease. Scientists discovered that tiny messengers released by fat tissue, called extracellular vesicles, can ca...
www.sciencedaily.com
October 4, 2025 at 1:34 AM
Obesity may directly drive Alzheimer’s disease. Scientists discovered that tiny messengers released by fat tissue, called extracellular vesicles, can carry harmful signals that accelerate the buildup of amyloid-β plaques in the brain.
www.sciencedaily.com/releases/202...
www.sciencedaily.com/releases/202...
Reposted by Natalie Turner
Bioengineering assistant professor Marley Dewey has received a National Institutes of Health (NIH) research award to support her work on recently discovered extracellular vesicles that play an important role in tissue repair.👏
Click here to read more: engineering.ucsb.edu/news/marley-...
Click here to read more: engineering.ucsb.edu/news/marley-...
September 9, 2025 at 7:30 PM
Bioengineering assistant professor Marley Dewey has received a National Institutes of Health (NIH) research award to support her work on recently discovered extracellular vesicles that play an important role in tissue repair.👏
Click here to read more: engineering.ucsb.edu/news/marley-...
Click here to read more: engineering.ucsb.edu/news/marley-...
Reposted by Natalie Turner
The new issue of #ScienceSignaling is out!
A study of fruit flies shows a common gut bacterium can enhance the rewarding properties of amphetamines, researchers uncover how proteins in extracellular vesicles can offer clues to HIV blockade, and more. https://scim.ag/45Up9V6
A study of fruit flies shows a common gut bacterium can enhance the rewarding properties of amphetamines, researchers uncover how proteins in extracellular vesicles can offer clues to HIV blockade, and more. https://scim.ag/45Up9V6
September 9, 2025 at 9:00 PM
The new issue of #ScienceSignaling is out!
A study of fruit flies shows a common gut bacterium can enhance the rewarding properties of amphetamines, researchers uncover how proteins in extracellular vesicles can offer clues to HIV blockade, and more. https://scim.ag/45Up9V6
A study of fruit flies shows a common gut bacterium can enhance the rewarding properties of amphetamines, researchers uncover how proteins in extracellular vesicles can offer clues to HIV blockade, and more. https://scim.ag/45Up9V6
EV-microRNAs may serve as early predictors of subfertility in dairy cows.
Congrats Pevindu for this final publication from his PhD and our time with Prof Murray Mitchell at QUT in Brisbane, Australia. 🇦🇺
#extracellularvesicles #biomarkers
isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
Congrats Pevindu for this final publication from his PhD and our time with Prof Murray Mitchell at QUT in Brisbane, Australia. 🇦🇺
#extracellularvesicles #biomarkers
isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
MicroRNA (miRNA) in Plasma Small Extracellular Vesicles (sEV) as Potential Early Indicators of Dairy Cow Subfertility
Pregnancy and live birth rates are commonly used metrics to define fertility in humans and animals. The impact of aberrant microRNA (miRNA) expression on fertility-related genes represents a signific....
isevjournals.onlinelibrary.wiley.com
September 1, 2025 at 3:08 PM
EV-microRNAs may serve as early predictors of subfertility in dairy cows.
Congrats Pevindu for this final publication from his PhD and our time with Prof Murray Mitchell at QUT in Brisbane, Australia. 🇦🇺
#extracellularvesicles #biomarkers
isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
Congrats Pevindu for this final publication from his PhD and our time with Prof Murray Mitchell at QUT in Brisbane, Australia. 🇦🇺
#extracellularvesicles #biomarkers
isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Natalie Turner
Dr. Dolores Di Vizio received the International Society for Extracellular Vesicles (ISEV) Special Achievement Award for her work showing large extracellular vesicles are functional mediators of #cancer progression. @isev.org
bioquicknews.com/isev-2025-sp...
bioquicknews.com/isev-2025-sp...
July 25, 2025 at 12:04 AM
Dr. Dolores Di Vizio received the International Society for Extracellular Vesicles (ISEV) Special Achievement Award for her work showing large extracellular vesicles are functional mediators of #cancer progression. @isev.org
bioquicknews.com/isev-2025-sp...
bioquicknews.com/isev-2025-sp...
Reposted by Natalie Turner
Very excited to share my postdoc work- out now at PNAS!
Learn more about how neurons facing chronic autophagic stress compensate by upregulating two secretion pathways
Autophagic stress activates distinct compensatory secretory pathways in neurons | PNAS www.pnas.org/doi/10.1073/...
Learn more about how neurons facing chronic autophagic stress compensate by upregulating two secretion pathways
Autophagic stress activates distinct compensatory secretory pathways in neurons | PNAS www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
July 7, 2025 at 7:38 PM
Very excited to share my postdoc work- out now at PNAS!
Learn more about how neurons facing chronic autophagic stress compensate by upregulating two secretion pathways
Autophagic stress activates distinct compensatory secretory pathways in neurons | PNAS www.pnas.org/doi/10.1073/...
Learn more about how neurons facing chronic autophagic stress compensate by upregulating two secretion pathways
Autophagic stress activates distinct compensatory secretory pathways in neurons | PNAS www.pnas.org/doi/10.1073/...
Reposted by Natalie Turner
This rate of validation suggests that affinity reagents such as antibodies should be considered non-specific until proven otherwise:
357 validated antibodies out of 1,124 tested.
.
357 validated antibodies out of 1,124 tested.
.
June 25, 2025 at 7:42 PM
This rate of validation suggests that affinity reagents such as antibodies should be considered non-specific until proven otherwise:
357 validated antibodies out of 1,124 tested.
.
357 validated antibodies out of 1,124 tested.
.
Reposted by Natalie Turner
New organ clock data support the anti-aging benefits of estrogen for postmenopausal women. Reviewed here in context with previous and other recent reports.
erictopol.substack.com/p/new-anti-a...
erictopol.substack.com/p/new-anti-a...
July 5, 2025 at 5:09 PM
New organ clock data support the anti-aging benefits of estrogen for postmenopausal women. Reviewed here in context with previous and other recent reports.
erictopol.substack.com/p/new-anti-a...
erictopol.substack.com/p/new-anti-a...
Reposted by Natalie Turner
‼️ Job alert 🚨: I have an open 3-year postdoc position in my lab to develop novel crosslinking mass spectrometry workflows. 🧪🧪 So if you want to do cool stuff in protein MS, please apply ! ⬇️ Please RT
www.verwaltung.uni-halle.de/dezern3/Auss...
#Academicsky
#Chemsky
#teammassspec
www.verwaltung.uni-halle.de/dezern3/Auss...
#Academicsky
#Chemsky
#teammassspec
www.verwaltung.uni-halle.de
June 25, 2025 at 12:44 PM
‼️ Job alert 🚨: I have an open 3-year postdoc position in my lab to develop novel crosslinking mass spectrometry workflows. 🧪🧪 So if you want to do cool stuff in protein MS, please apply ! ⬇️ Please RT
www.verwaltung.uni-halle.de/dezern3/Auss...
#Academicsky
#Chemsky
#teammassspec
www.verwaltung.uni-halle.de/dezern3/Auss...
#Academicsky
#Chemsky
#teammassspec
Reposted by Natalie Turner
Excited to share part two of our plant extracellular vesicles story on BioRxiv! Using proximity labeling the awesome power of genetics to figure out how these lil’ guys are secreted.
Part one: doi.org/10.1002/jev2...
Part two:
www.biorxiv.org/content/10.1...
Part one: doi.org/10.1002/jev2...
Part two:
www.biorxiv.org/content/10.1...
June 22, 2025 at 9:36 PM
Excited to share part two of our plant extracellular vesicles story on BioRxiv! Using proximity labeling the awesome power of genetics to figure out how these lil’ guys are secreted.
Part one: doi.org/10.1002/jev2...
Part two:
www.biorxiv.org/content/10.1...
Part one: doi.org/10.1002/jev2...
Part two:
www.biorxiv.org/content/10.1...
Reposted by Natalie Turner
People are having very strange conversations with ChatGPT, in which they discover secret cabals or conspiracies or that we are all in fact living in The Matrix.
It sends these people into delusional spirals.
Then ChatGPT tells them to email me about it.
www.nytimes.com/2025/06/13/t...
It sends these people into delusional spirals.
Then ChatGPT tells them to email me about it.
www.nytimes.com/2025/06/13/t...
They Asked an A.I. Chatbot Questions. The Answers Sent Them Spiraling.
www.nytimes.com
June 13, 2025 at 9:44 AM
People are having very strange conversations with ChatGPT, in which they discover secret cabals or conspiracies or that we are all in fact living in The Matrix.
It sends these people into delusional spirals.
Then ChatGPT tells them to email me about it.
www.nytimes.com/2025/06/13/t...
It sends these people into delusional spirals.
Then ChatGPT tells them to email me about it.
www.nytimes.com/2025/06/13/t...
💡 This week I attended #ASMS2025 in Baltimore to present 'Deep proteome characterization unveils distinct secretory phenotypes of Wild Type and familial Alzheimer's Disease organoids'. Our findings shed light on how secretory differences may influence disease progression and biomarker discovery.
June 6, 2025 at 12:59 PM
💡 This week I attended #ASMS2025 in Baltimore to present 'Deep proteome characterization unveils distinct secretory phenotypes of Wild Type and familial Alzheimer's Disease organoids'. Our findings shed light on how secretory differences may influence disease progression and biomarker discovery.
Reposted by Natalie Turner
Heading to #ASMS2025 next week? Check out our talks and posters from the Yates lab!
See the poster below for details 😁👇
#proteomics
#extracellularvesicles
#massspec
#glycoproteomics
@jyates.bsky.social
See the poster below for details 😁👇
#proteomics
#extracellularvesicles
#massspec
#glycoproteomics
@jyates.bsky.social
May 30, 2025 at 3:24 AM
Heading to #ASMS2025 next week? Check out our talks and posters from the Yates lab!
See the poster below for details 😁👇
#proteomics
#extracellularvesicles
#massspec
#glycoproteomics
@jyates.bsky.social
See the poster below for details 😁👇
#proteomics
#extracellularvesicles
#massspec
#glycoproteomics
@jyates.bsky.social
Reposted by Natalie Turner
Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab
May 13, 2025 at 11:37 PM
Yesterday, the NIH R35 “Outstanding Investigator” grant to fund scientists in my lab studying antibiotic resistance was terminated for reasons not related to the content of the science, or any actions taken by me or members of my lab
Ahhh my trusty qEV column, how I have missed you ❤️❤️❤️
Although, it’s still like watching paint dry 🤦🏻♀️😴
#extracellularvesicles #exosomes
Although, it’s still like watching paint dry 🤦🏻♀️😴
#extracellularvesicles #exosomes
May 6, 2025 at 7:06 PM
Ahhh my trusty qEV column, how I have missed you ❤️❤️❤️
Although, it’s still like watching paint dry 🤦🏻♀️😴
#extracellularvesicles #exosomes
Although, it’s still like watching paint dry 🤦🏻♀️😴
#extracellularvesicles #exosomes
Good news! My article received enough views to be a Top Viewed Article. Read it here:
onlinelibrary.wiley.com/doi/10.1002/...
#TopViewedArticle @wiley.com
#milk #extracellularvesicles #proteomics #bioinformatics
onlinelibrary.wiley.com/doi/10.1002/...
#TopViewedArticle @wiley.com
#milk #extracellularvesicles #proteomics #bioinformatics
Omics Analysis of Extracellular Vesicles Recovered from Infant Formula Products and Milk: Towards Personalized Infant Nutrition
Proteomics and next-generation small RNA-seq enables cross-species analysis of extracellular vesicles (EVs) recovered from human milk, cow milk (CM), and lyophilized infant formula (IF) products. IF ...
onlinelibrary.wiley.com
April 16, 2025 at 3:10 PM
Good news! My article received enough views to be a Top Viewed Article. Read it here:
onlinelibrary.wiley.com/doi/10.1002/...
#TopViewedArticle @wiley.com
#milk #extracellularvesicles #proteomics #bioinformatics
onlinelibrary.wiley.com/doi/10.1002/...
#TopViewedArticle @wiley.com
#milk #extracellularvesicles #proteomics #bioinformatics
Reposted by Natalie Turner
Wow! Mitochondria can actually be transferred to other cells if needed through nanotubes, in extracellular bubble-shaped vesicles, or by free floating through the blood. buff.ly/33kcDdS
Donating mitochondria to another cell may help to repair damaged cells or support immune function.
#medsky 🧪
Donating mitochondria to another cell may help to repair damaged cells or support immune function.
#medsky 🧪
Cells are swapping their mitochondria. What does this mean for our health?
Researchers are studying why the energy factories are moving between cells and whether the process can be harnessed to treat cancer and other diseases.
buff.ly
April 10, 2025 at 3:59 AM
Wow! Mitochondria can actually be transferred to other cells if needed through nanotubes, in extracellular bubble-shaped vesicles, or by free floating through the blood. buff.ly/33kcDdS
Donating mitochondria to another cell may help to repair damaged cells or support immune function.
#medsky 🧪
Donating mitochondria to another cell may help to repair damaged cells or support immune function.
#medsky 🧪
Reposted by Natalie Turner
Cool new study showing glycoRNAs on circulating extracellular vesicles may have diagnostic utility #glycotime
Advancing #glycoRNA imaging with FRET-based detection and expanding the scope of their presentation to extracellular vesicles - interestingly high levels of sialoglycoRNAs on blood EVs can be predictive of having cancer @naturecomms.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com
April 11, 2025 at 3:16 PM
Cool new study showing glycoRNAs on circulating extracellular vesicles may have diagnostic utility #glycotime
pubs.acs.org/doi/10.1021/...
Comparison of Protein Solubilization and Normalization Methods for #Proteomics Analysis of Extracellular Vesicles from Urine
#extracellularvesicles
Comparison of Protein Solubilization and Normalization Methods for #Proteomics Analysis of Extracellular Vesicles from Urine
#extracellularvesicles
Comparison of Protein Solubilization and Normalization Methods for Proteomics Analysis of Extracellular Vesicles from Urine
Extracellular vesicles (EVs) play a vital role in numerous biological processes. Proteomic research of EVs is crucial for understanding their functions and potential therapeutic implications. Despite ...
pubs.acs.org
April 6, 2025 at 10:26 PM
pubs.acs.org/doi/10.1021/...
Comparison of Protein Solubilization and Normalization Methods for #Proteomics Analysis of Extracellular Vesicles from Urine
#extracellularvesicles
Comparison of Protein Solubilization and Normalization Methods for #Proteomics Analysis of Extracellular Vesicles from Urine
#extracellularvesicles
Linking this here for all #bioinformatics #proteomics #lipidomics #genomics #transcriptomics people…
We are really experiencing a data reproducibility crisis, strongly linked to poor reporting practices.
It’s time for a change- but needs your support! 🙏
www.linkedin.com/posts/natali...
We are really experiencing a data reproducibility crisis, strongly linked to poor reporting practices.
It’s time for a change- but needs your support! 🙏
www.linkedin.com/posts/natali...
#bioinformatics #omics #proteomics #transcriptomics #genomics #lipidomics… | Natalie Turner | 16 comments
This should probably be a blog post, but I don't have a blog, so...
For the past 3 months I have been a TA (= teaching assistant, for all those not in the US) for an Applied Bioinformatics an...
www.linkedin.com
April 5, 2025 at 4:16 PM
Linking this here for all #bioinformatics #proteomics #lipidomics #genomics #transcriptomics people…
We are really experiencing a data reproducibility crisis, strongly linked to poor reporting practices.
It’s time for a change- but needs your support! 🙏
www.linkedin.com/posts/natali...
We are really experiencing a data reproducibility crisis, strongly linked to poor reporting practices.
It’s time for a change- but needs your support! 🙏
www.linkedin.com/posts/natali...
‘The Diminishing of American Science’
The consequences of the NIH crisis is likely going to be far more extreme than we can even predict.
Prof Yates sums it up nicely for the Analytical Scientist.
#TeamMassSpec #proteomics #extracellularvesicles
theanalyticalscientist.com/business-edu...
The consequences of the NIH crisis is likely going to be far more extreme than we can even predict.
Prof Yates sums it up nicely for the Analytical Scientist.
#TeamMassSpec #proteomics #extracellularvesicles
theanalyticalscientist.com/business-edu...
The Diminishing of American Science
If US laboratories will have less money to pay staff, conduct research, and collaborate American science will be greatly diminished
theanalyticalscientist.com
March 22, 2025 at 4:29 AM
‘The Diminishing of American Science’
The consequences of the NIH crisis is likely going to be far more extreme than we can even predict.
Prof Yates sums it up nicely for the Analytical Scientist.
#TeamMassSpec #proteomics #extracellularvesicles
theanalyticalscientist.com/business-edu...
The consequences of the NIH crisis is likely going to be far more extreme than we can even predict.
Prof Yates sums it up nicely for the Analytical Scientist.
#TeamMassSpec #proteomics #extracellularvesicles
theanalyticalscientist.com/business-edu...
Reposted by Natalie Turner
Quantitative Lipid Analysis of Extracellular Vesicle Preparations: A Perspective #JEV #MassSpec isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
Quantitative Lipid Analysis of Extracellular Vesicle Preparations: A Perspective
Quantitative lipidomic analysis performed by mass spectrometry is required for determination of the lipid content of extracellular vesicles (EVs). Such methods can provide information about the total...
isevjournals.onlinelibrary.wiley.com
March 17, 2025 at 8:33 PM
Quantitative Lipid Analysis of Extracellular Vesicle Preparations: A Perspective #JEV #MassSpec isevjournals.onlinelibrary.wiley.com/doi/10.1002/...
‘Uptake of small #extracellularvesicles by recipient cells is facilitated by paracrine adhesion signalling’ 🧐
Of note is that this study was performed using 2 tumour cell lines and all sEVs isolated were CD63 positive, regardless of cell type and EV subtype.
www.nature.com/articles/s41...
Of note is that this study was performed using 2 tumour cell lines and all sEVs isolated were CD63 positive, regardless of cell type and EV subtype.
www.nature.com/articles/s41...
Uptake of small extracellular vesicles by recipient cells is facilitated by paracrine adhesion signaling - Nature Communications
Hirosawa et al. use single particle tracking and superresolution imaging to demonstrate that tumor-derived small extracellular vesicles (sEVs) undergo clathrin-independent endocytosis, with some using...
www.nature.com
March 18, 2025 at 1:28 AM
‘Uptake of small #extracellularvesicles by recipient cells is facilitated by paracrine adhesion signalling’ 🧐
Of note is that this study was performed using 2 tumour cell lines and all sEVs isolated were CD63 positive, regardless of cell type and EV subtype.
www.nature.com/articles/s41...
Of note is that this study was performed using 2 tumour cell lines and all sEVs isolated were CD63 positive, regardless of cell type and EV subtype.
www.nature.com/articles/s41...