Caroline Doherty
@mouthpipette.bsky.social
Postdoc in the Laird Lab studying germ cell growth dynamics at UCSF. PhD with the Shvartsman and Gavis labs at Princeton. She/her. Uffda.
Reposted by Caroline Doherty
Reposted by Caroline Doherty
The #devbio project that encompassed the majority of my postdoc is finally out! Huge thanks to my coauthors and our collaborators without whom this work would not have been possible, and my adviser Eszter Posfai who let me play with a light sheet microscope and some colorful mice :)
Thrilled to share our work using live imaging to understand how Epiblast (future embryo proper) and Primitive Endoderm (future extraembryonic tissues) cell fates segregate in the preimplantation mouse embryo. Gargantuan effort led by amazing @rpkimyip.bsky.social, David Denberg and Denis Faerberg!
August 3, 2025 at 4:45 PM
The #devbio project that encompassed the majority of my postdoc is finally out! Huge thanks to my coauthors and our collaborators without whom this work would not have been possible, and my adviser Eszter Posfai who let me play with a light sheet microscope and some colorful mice :)
Reposted by Caroline Doherty
Thrilled to share our work using live imaging to understand how Epiblast (future embryo proper) and Primitive Endoderm (future extraembryonic tissues) cell fates segregate in the preimplantation mouse embryo. Gargantuan effort led by amazing @rpkimyip.bsky.social, David Denberg and Denis Faerberg!
August 2, 2025 at 7:31 PM
Thrilled to share our work using live imaging to understand how Epiblast (future embryo proper) and Primitive Endoderm (future extraembryonic tissues) cell fates segregate in the preimplantation mouse embryo. Gargantuan effort led by amazing @rpkimyip.bsky.social, David Denberg and Denis Faerberg!
Reposted by Caroline Doherty
WAVE complex forms linear arrays at negative membrane curvature to instruct #lamellipodia formation, say Muziyue Wu, Orion Weiner @oweinerlab.bsky.social and colleagues: rupress.org/jcb/article/...
#Biophysics #Cytoskeleton #Migration #Motility #Actin
#Biophysics #Cytoskeleton #Migration #Motility #Actin
July 23, 2025 at 6:45 PM
WAVE complex forms linear arrays at negative membrane curvature to instruct #lamellipodia formation, say Muziyue Wu, Orion Weiner @oweinerlab.bsky.social and colleagues: rupress.org/jcb/article/...
#Biophysics #Cytoskeleton #Migration #Motility #Actin
#Biophysics #Cytoskeleton #Migration #Motility #Actin
Reposted by Caroline Doherty
We’re hiring! Our lab at WashU has an opening for a Senior/Staff Scientist position. If you're passionate about ovarian physiology, oocyte quality, and excited to contribute to a dynamic and growing team, we’d love to hear from you! Reach out to me directly for more information.
July 21, 2025 at 10:39 PM
We’re hiring! Our lab at WashU has an opening for a Senior/Staff Scientist position. If you're passionate about ovarian physiology, oocyte quality, and excited to contribute to a dynamic and growing team, we’d love to hear from you! Reach out to me directly for more information.
Reposted by Caroline Doherty
Tomorrow's front page of the Minnesota Star Tribune
June 15, 2025 at 2:47 AM
Tomorrow's front page of the Minnesota Star Tribune
Reposted by Caroline Doherty
Check out our latest blog post giving an overview on the 2025 Annual Symposium, held early this month in Chicago:
www.jccfund.org/blog/2025-an...
www.jccfund.org/blog/2025-an...
2025 Annual Symposium Overview - Jane Coffin Childs Memorial Fund
The Jane Coffin Childs Memorial Fund for Medical Research community reconvened from May 7th – 9th in Chicago for the 2025 Annual Symposium. In this blog we’ll give an overview for the entire Symposium...
www.jccfund.org
May 22, 2025 at 1:23 PM
Check out our latest blog post giving an overview on the 2025 Annual Symposium, held early this month in Chicago:
www.jccfund.org/blog/2025-an...
www.jccfund.org/blog/2025-an...
Reposted by Caroline Doherty
Some of the CDC's main channels for communicating urgent health information to the public have gone silent.
Diseases are spreading. The CDC isn't warning the public like it was months ago
Some of the CDC's main channels for communicating urgent health information to the public have gone silent.
www.npr.org
May 21, 2025 at 11:24 AM
Some of the CDC's main channels for communicating urgent health information to the public have gone silent.
Reposted by Caroline Doherty
#DBfeature #Oocyte
Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
by Monique Mills, Ewelina Bolcun-Filas
www.sciencedirect.com/science/arti...
Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
by Monique Mills, Ewelina Bolcun-Filas
www.sciencedirect.com/science/arti...
May 21, 2025 at 12:20 PM
#DBfeature #Oocyte
Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
by Monique Mills, Ewelina Bolcun-Filas
www.sciencedirect.com/science/arti...
Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes
by Monique Mills, Ewelina Bolcun-Filas
www.sciencedirect.com/science/arti...
Reposted by Caroline Doherty
The Trump administration this week eliminated funding for Harvard research projects across a host of areas, from the origins of breast cancer and the impact of nutrition on fertility to antibiotic resistance.
Feds yank funds from Harvard breast cancer, fertility, antibiotics research
The Trump administration is following through on threats to terminate $2.7 billion dollars in federal grants and other funding at Harvard University, punishment for alleged antisemitism on campus. One...
www.wbur.org
May 16, 2025 at 8:31 PM
The Trump administration this week eliminated funding for Harvard research projects across a host of areas, from the origins of breast cancer and the impact of nutrition on fertility to antibiotic resistance.
Reposted by Caroline Doherty
Our universities are so good that our adversaries send their children to be educated here. We’re dismantling that unbelievable strategic advantage, hurting our own children and our own health in the process.
Shutting down medical research — not just within NIH, but everywhere that’s funded by NIH — will have long-term effects on medicine & short-term effects on state, higher education & hospital budgets. This affects all of us, not just researchers.
The assault on NIH is a test for how the national media covers the Trump admin: Trump is shutting down medical research!
That is easy to communicate. Will they treat it as a 5 alarm fire in a way that forces the government to respond, or will they downplay & caveat it?
That is easy to communicate. Will they treat it as a 5 alarm fire in a way that forces the government to respond, or will they downplay & caveat it?
January 23, 2025 at 2:01 AM
Our universities are so good that our adversaries send their children to be educated here. We’re dismantling that unbelievable strategic advantage, hurting our own children and our own health in the process.
Reposted by Caroline Doherty
Congrats to the 2025 JCC Symposium Poster Presentation Award Winners: Dr. Xinyu Ling, Dr. Pablo Villar, and Dr. Zhuoning Zou!!!
May 9, 2025 at 4:46 PM
Congrats to the 2025 JCC Symposium Poster Presentation Award Winners: Dr. Xinyu Ling, Dr. Pablo Villar, and Dr. Zhuoning Zou!!!
Reposted by Caroline Doherty
It is a cloudy day in Chicago, but the science is shining here inside the Gleacher Center at the University of Chicago at the 2025 JCC Annual Symposium.
First up this morning: science talks from our 3rd year JCC Fellows ... buckle up!
1 / a lot
First up this morning: science talks from our 3rd year JCC Fellows ... buckle up!
1 / a lot
May 8, 2025 at 1:59 PM
It is a cloudy day in Chicago, but the science is shining here inside the Gleacher Center at the University of Chicago at the 2025 JCC Annual Symposium.
First up this morning: science talks from our 3rd year JCC Fellows ... buckle up!
1 / a lot
First up this morning: science talks from our 3rd year JCC Fellows ... buckle up!
1 / a lot
Reposted by Caroline Doherty
Congrats to the the 2025 JCC Symposium science talk award winners: Dr. Caroline Doherty @mouthpipette.bsky.social , Dr. Phi Nguyen @phi-nguyen.bsky.social , and Dr. Leo Yan!!!
May 9, 2025 at 4:39 PM
Congrats to the the 2025 JCC Symposium science talk award winners: Dr. Caroline Doherty @mouthpipette.bsky.social , Dr. Phi Nguyen @phi-nguyen.bsky.social , and Dr. Leo Yan!!!
Reposted by Caroline Doherty
A duo of preprints on the dynamics of the first cell fate decision in mouse by Madeleine Chalifoux (first grad student in the lab!) and Maria Avdeeva (Flatiron).
We use quantitative live imaging of key cell fate determinants to follow the segregation of inner cell mass and trophectoderm lineages.
We use quantitative live imaging of key cell fate determinants to follow the segregation of inner cell mass and trophectoderm lineages.
March 5, 2025 at 2:54 AM
A duo of preprints on the dynamics of the first cell fate decision in mouse by Madeleine Chalifoux (first grad student in the lab!) and Maria Avdeeva (Flatiron).
We use quantitative live imaging of key cell fate determinants to follow the segregation of inner cell mass and trophectoderm lineages.
We use quantitative live imaging of key cell fate determinants to follow the segregation of inner cell mass and trophectoderm lineages.
Reposted by Caroline Doherty
I understand that ChatGPT is down and fortunately this is not a problem for me as I have spent considerable time developing a local language model that I am able to run autonomously, fueled by Coke Zero and snacks
January 23, 2025 at 4:18 PM
I understand that ChatGPT is down and fortunately this is not a problem for me as I have spent considerable time developing a local language model that I am able to run autonomously, fueled by Coke Zero and snacks
Reposted by Caroline Doherty
A Hallmark movie where instead of moving to a small town and falling in love, I move to the country and I eat a lot of peaches.
December 17, 2024 at 1:44 PM
A Hallmark movie where instead of moving to a small town and falling in love, I move to the country and I eat a lot of peaches.
Reposted by Caroline Doherty
Any Minnesotans on here?
December 10, 2024 at 5:27 PM
Any Minnesotans on here?
Reposted by Caroline Doherty
I don't know who needs to know this, but Pro Publica has an online thing that will format a letter to your US health insurance company to demand the records behind a claim denial. (which the insurance is then legally required to provide in most cases)
projects.propublica.org/claimfile/
projects.propublica.org/claimfile/
Find Out Why Health Insurance Denied Your Claim
You likely have the right to access records that explain why your insurer denied your claim or prior authorization request. Use ProPublica’s free tool to generate a letter requesting your claim file f...
projects.propublica.org
March 22, 2024 at 1:25 PM
I don't know who needs to know this, but Pro Publica has an online thing that will format a letter to your US health insurance company to demand the records behind a claim denial. (which the insurance is then legally required to provide in most cases)
projects.propublica.org/claimfile/
projects.propublica.org/claimfile/
Tsunami warning? Cool cool cool cool cool cool cool.
December 5, 2024 at 7:18 PM
Tsunami warning? Cool cool cool cool cool cool cool.
Reposted by Caroline Doherty
🎨 In case anyone need…
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
November 23, 2024 at 3:50 PM
🎨 In case anyone need…
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool 🙏!
Check it out 👇
bioart.niaid.nih.gov
Hot off the press with the thesis work of @ezlevy.bsky.social and @isabellaleite.bsky.social! The @eposfai.bsky.social and Shvartsman labs show how the balance of cell protusions and cyst fractionation controls the variability in germline cyst size in mice.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
A tug-of-war between germ cell motility and intercellular bridges controls germline cyst formation in mice
Gametes in many species develop in cysts—clusters of germ cells formed by incomplete cytokinesis—that remain connected through intercellular bridges (…
www.sciencedirect.com
November 20, 2024 at 8:22 PM
Hot off the press with the thesis work of @ezlevy.bsky.social and @isabellaleite.bsky.social! The @eposfai.bsky.social and Shvartsman labs show how the balance of cell protusions and cyst fractionation controls the variability in germline cyst size in mice.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Check out this work from my former labmates! The movies are insane!
Check out our new paper in @currentbiology.bsky.social by amazing grad students @ezlevy.bsky.social and @isabellaleite.bsky.social “A tug-of-war between germ cell motility and intercellular bridges controls germline cyst formation in mice”
authors.elsevier.com/a/1k7fg3QW8S...
authors.elsevier.com/a/1k7fg3QW8S...
November 20, 2024 at 8:16 PM
Check out this work from my former labmates! The movies are insane!
Reposted by Caroline Doherty
You asked for it...
November 19, 2024 at 11:31 PM
You asked for it...