Marie Binvignat
@mbinvignat.bsky.social
MD. PhD in Systems Immunology Sorbonne University
Rheumatology Fellow AP-HP
Rheumatology Fellow AP-HP
Thrilled to share our new paper comparing different LLMs to extract TNFi reasons and treatment trajectories from UCSF de-identified EHR data with @bmeow19.bsky.social, A. Garcia-Agundez and @jyazdanymd.bsky.social published in JAMIA open.
academic.oup.com/jamiaopen/ar...
@ucsf-bchsi.bsky.social
academic.oup.com/jamiaopen/ar...
@ucsf-bchsi.bsky.social
November 14, 2025 at 9:36 PM
Thrilled to share our new paper comparing different LLMs to extract TNFi reasons and treatment trajectories from UCSF de-identified EHR data with @bmeow19.bsky.social, A. Garcia-Agundez and @jyazdanymd.bsky.social published in JAMIA open.
academic.oup.com/jamiaopen/ar...
@ucsf-bchsi.bsky.social
academic.oup.com/jamiaopen/ar...
@ucsf-bchsi.bsky.social
Reposted by Marie Binvignat
A paper in Nature describes an AI system that can prove complex mathematical theories. The system, Google DeepMind’s AlphaProof, has achieved a silver medal-worthy performance at the 2024 International Mathematics Olympiad. go.nature.com/4qUObvN 🧪
November 12, 2025 at 11:18 PM
A paper in Nature describes an AI system that can prove complex mathematical theories. The system, Google DeepMind’s AlphaProof, has achieved a silver medal-worthy performance at the 2024 International Mathematics Olympiad. go.nature.com/4qUObvN 🧪
Reposted by Marie Binvignat
The T cells in these patients showed increased metabolic activity. Elevated levels of inflammatory molecules (IL-6, IL-12, and type I interferon) may be driving the aggressive T cell behavior. #ACR25
October 28, 2025 at 2:14 PM
The T cells in these patients showed increased metabolic activity. Elevated levels of inflammatory molecules (IL-6, IL-12, and type I interferon) may be driving the aggressive T cell behavior. #ACR25
Reposted by Marie Binvignat
Atul Butte, MD, PhD, helped define the field of translational bioinformatics and inspired countless colleagues and trainees.
He will be remembered for his brilliant mind, infectious optimism, generous mentorship.
He will be remembered for his brilliant mind, infectious optimism, generous mentorship.
Remembering Atul Butte
This Medical News article is in remembrance of Atul Butte, MD, PhD, a pioneer in using data science to improve health.
jamanetwork.com
October 3, 2025 at 3:06 PM
Atul Butte, MD, PhD, helped define the field of translational bioinformatics and inspired countless colleagues and trainees.
He will be remembered for his brilliant mind, infectious optimism, generous mentorship.
He will be remembered for his brilliant mind, infectious optimism, generous mentorship.
Reposted by Marie Binvignat
Fresh from the oven 🧨💥
We show that CD4 T cells, especially Tregs, control host-microbiota symbiosis and intestinal barrier integrity to prevent inflammaging, tissue senescence and aging-related multimorbidity
🔥 👵🏻
www.science.org/doi/10.1126/...
We show that CD4 T cells, especially Tregs, control host-microbiota symbiosis and intestinal barrier integrity to prevent inflammaging, tissue senescence and aging-related multimorbidity
🔥 👵🏻
www.science.org/doi/10.1126/...
CD4 T cell therapy counteracts inflammaging and senescence by preserving gut barrier integrity
Treg cells safeguard the intestinal barrier to prevent inflammaging and senescence in a mouse model of premature aging.
www.science.org
August 6, 2025 at 4:58 PM
Fresh from the oven 🧨💥
We show that CD4 T cells, especially Tregs, control host-microbiota symbiosis and intestinal barrier integrity to prevent inflammaging, tissue senescence and aging-related multimorbidity
🔥 👵🏻
www.science.org/doi/10.1126/...
We show that CD4 T cells, especially Tregs, control host-microbiota symbiosis and intestinal barrier integrity to prevent inflammaging, tissue senescence and aging-related multimorbidity
🔥 👵🏻
www.science.org/doi/10.1126/...
Congrats to @mariamarcosalvador.bsky.social on her first publication, just out in @oacjournal.bsky.social !
A systematic literature review on TCR and HLA in osteoarthritis:
🔗 www.oarsijournal.com/article/S106...
@enkrnita.bsky.social @jeremiesellam.bsky.social @sorbonne-universite.fr
A systematic literature review on TCR and HLA in osteoarthritis:
🔗 www.oarsijournal.com/article/S106...
@enkrnita.bsky.social @jeremiesellam.bsky.social @sorbonne-universite.fr
T-cell receptor repertoire and HLA in osteoarthritis: A systematic literature review
The aim of this systematic literature review was to provide a comprehensive overview
of T-Cell Receptor (TCR) mediated immunity research in osteoarthritis (OA).
www.oarsijournal.com
September 8, 2025 at 7:04 PM
Congrats to @mariamarcosalvador.bsky.social on her first publication, just out in @oacjournal.bsky.social !
A systematic literature review on TCR and HLA in osteoarthritis:
🔗 www.oarsijournal.com/article/S106...
@enkrnita.bsky.social @jeremiesellam.bsky.social @sorbonne-universite.fr
A systematic literature review on TCR and HLA in osteoarthritis:
🔗 www.oarsijournal.com/article/S106...
@enkrnita.bsky.social @jeremiesellam.bsky.social @sorbonne-universite.fr
Reposted by Marie Binvignat
The UCSF community mourns the passing of Atul Butte, MD, PhD, a bold thinker, inspiring mentor and founding director of the Bakar Computational Health Sciences Institute.
tiny.ucsf.edu/tGz3QY
tiny.ucsf.edu/tGz3QY
UCSF Bioinformatics Pioneer Atul Butte Dies at 55
Atul Butte, who championed the use of big data in science and health care and inspired a generation of trainees at UC San Francisco and beyond to pursue the fields he pioneered — translational and cli...
tiny.ucsf.edu
June 24, 2025 at 11:18 PM
The UCSF community mourns the passing of Atul Butte, MD, PhD, a bold thinker, inspiring mentor and founding director of the Bakar Computational Health Sciences Institute.
tiny.ucsf.edu/tGz3QY
tiny.ucsf.edu/tGz3QY
Reposted by Marie Binvignat
Review @natrevrheum.nature.com @deepakarao.bsky.social
Immune-cell profiling to guide stratification and treatment of patients with rheumatic diseases
www.nature.com/articles/s41...
Immune-cell profiling to guide stratification and treatment of patients with rheumatic diseases
www.nature.com/articles/s41...
Immune-cell profiling to guide stratification and treatment of patients with rheumatic diseases - Nature Reviews Rheumatology
In this Review article, the potential of cytometry- and single-cell RNA sequencing-based immune profiling for aiding the diagnosis and personalized treatment of rheumatic diseases is discussed.
www.nature.com
September 1, 2025 at 7:38 PM
Review @natrevrheum.nature.com @deepakarao.bsky.social
Immune-cell profiling to guide stratification and treatment of patients with rheumatic diseases
www.nature.com/articles/s41...
Immune-cell profiling to guide stratification and treatment of patients with rheumatic diseases
www.nature.com/articles/s41...
Reposted by Marie Binvignat
Recently in #Science #Immunology: Van der Veeken & al @ IMP @viennabiocenter.bsky.social generated 🐁 w auxin-inducible degradable #Foxp3! Tissue #Tregs minimally unaffected @ homeostasis but highly dependent on continuous Foxp3 activity in models of #autoimmunity, #viral #infection, & #cancer !
Inducible protein degradation reveals inflammation-dependent function of the Treg cell lineage–defining transcription factor Foxp3
Acute Foxp3 protein depletion selectively affects Treg cells responding to type 1 inflammation.
www.science.org
June 20, 2025 at 6:51 AM
Recently in #Science #Immunology: Van der Veeken & al @ IMP @viennabiocenter.bsky.social generated 🐁 w auxin-inducible degradable #Foxp3! Tissue #Tregs minimally unaffected @ homeostasis but highly dependent on continuous Foxp3 activity in models of #autoimmunity, #viral #infection, & #cancer !
Reposted by Marie Binvignat
🚨 NEW 🚨
🤩 This month's Editors Choice (Clinical) is about intestinal health and hand #osteoarthritis
Read more from @mbinvignat.bsky.social @jeremiesellam.bsky.social - www.oarsijournal.com/article/S106...
🤩 This month's Editors Choice (Clinical) is about intestinal health and hand #osteoarthritis
Read more from @mbinvignat.bsky.social @jeremiesellam.bsky.social - www.oarsijournal.com/article/S106...
May 31, 2025 at 11:48 PM
🚨 NEW 🚨
🤩 This month's Editors Choice (Clinical) is about intestinal health and hand #osteoarthritis
Read more from @mbinvignat.bsky.social @jeremiesellam.bsky.social - www.oarsijournal.com/article/S106...
🤩 This month's Editors Choice (Clinical) is about intestinal health and hand #osteoarthritis
Read more from @mbinvignat.bsky.social @jeremiesellam.bsky.social - www.oarsijournal.com/article/S106...
Check out our new editorial on molecular endotypes and theratypes in osteoarthritis with @jeremiesellam.bsky.social, just out in Annals of the Rheumatic Diseases
ard.eular.org/article/S000...
@crsa-paris.bsky.social @sorbonne-universite.fr
ard.eular.org/article/S000...
@crsa-paris.bsky.social @sorbonne-universite.fr
Molecular endotypes and theratypes in osteoarthritis: transforming a concept into reality with deep learning and multiomics
Osteoarthritis (OA) is now understood as a heterogeneous disease in many respects,
including its clinical presentation, underlying pathophysiological mechanisms, and
response to treatments. Distinct p...
ard.eular.org
May 24, 2025 at 6:29 AM
Check out our new editorial on molecular endotypes and theratypes in osteoarthritis with @jeremiesellam.bsky.social, just out in Annals of the Rheumatic Diseases
ard.eular.org/article/S000...
@crsa-paris.bsky.social @sorbonne-universite.fr
ard.eular.org/article/S000...
@crsa-paris.bsky.social @sorbonne-universite.fr
Reposted by Marie Binvignat
We’re proud to celebrate @atulbutte.bsky.social on his election to the American Academy of Arts and Sciences, one of the nation’s oldest honor societies. A leader in biomedical data science, his work is reshaping how we diagnose and treat disease. tiny.ucsf.edu/CUz7gN
UCSF Scientist Receives High Honor for Exceptional Career
Researcher and campus leader Atul Butte, MD, PhD, has been recognized for his outstanding career in the computational and health sciences with induction into the American Academy of Arts and Sciences,...
tiny.ucsf.edu
May 1, 2025 at 6:20 PM
We’re proud to celebrate @atulbutte.bsky.social on his election to the American Academy of Arts and Sciences, one of the nation’s oldest honor societies. A leader in biomedical data science, his work is reshaping how we diagnose and treat disease. tiny.ucsf.edu/CUz7gN
Happy to share our new article on Intestinal Permeability serum biomarkers in Erosive hand OA with @jeremiesellam.bsky.social @larhumato.bsky.social @enkrnita.bsky.social and team
Read the paper here: www.oarsijournal.com/article/S106...
@crsa-paris.bsky.social @oacjournal.bsky.social
Read the paper here: www.oarsijournal.com/article/S106...
@crsa-paris.bsky.social @oacjournal.bsky.social
Serum intestinal permeability biomarkers are associated with erosive hand osteoarthritis and radiographic severity: results from the DIGICOD cohort
To investigate the association between intestinal permeability alteration and erosive
hand osteoarthritis (EHOA).
www.oarsijournal.com
April 8, 2025 at 6:39 AM
Happy to share our new article on Intestinal Permeability serum biomarkers in Erosive hand OA with @jeremiesellam.bsky.social @larhumato.bsky.social @enkrnita.bsky.social and team
Read the paper here: www.oarsijournal.com/article/S106...
@crsa-paris.bsky.social @oacjournal.bsky.social
Read the paper here: www.oarsijournal.com/article/S106...
@crsa-paris.bsky.social @oacjournal.bsky.social
Reposted by Marie Binvignat
