Kat Mayer-Barber,PhD
@mayerbarber.bsky.social
Cellular mucosal immunologist- lung- 🫁 innate immunity and inflammtion @IRP/NIAID/NIH - views my own
https://www.niaid.nih.gov/research/katrin-d-mayer-barber-dr-rer-nat-phd
https://www.niaid.nih.gov/research/katrin-d-mayer-barber-dr-rer-nat-phd
Pinned
Best #Nikolaus 🎅! Our paper on how the 🫁 microenvironment can shape #innate immunity against #viruses is out @sciimmunology.bsky.social This was a herculean effort brilliantly led by @pauljbaker.bsky.social who singlehandedly established the model in the lab during the pandemic. 🧪 #Immunosky 1/9
Reposted by Kat Mayer-Barber,PhD
A ‘simple’ experiment but an amazing gem of a reference!
Just stimulate blood, observe and describe…
#ImmunoSky
Just stimulate blood, observe and describe…
#ImmunoSky
Stimulating immune cells in vitro is a common experimental lab model. We profiled 150K blood immune cells treated with 11 different stimuli to compare the effects. The data are freely available for researchers. See the preprint for our findings and to access the data 🧪 doi.org/10.1101/2025...
July 6, 2025 at 1:18 PM
A ‘simple’ experiment but an amazing gem of a reference!
Just stimulate blood, observe and describe…
#ImmunoSky
Just stimulate blood, observe and describe…
#ImmunoSky
Reposted by Kat Mayer-Barber,PhD
Please share and distribute
ILC6 in Vancouver
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available
Secure your spot and discounted fees during early bird registration and come visit beautiful Vancouver.
ILC6 in Vancouver
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available
Secure your spot and discounted fees during early bird registration and come visit beautiful Vancouver.
January 15, 2026 at 2:42 PM
Please share and distribute
ILC6 in Vancouver
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available
Secure your spot and discounted fees during early bird registration and come visit beautiful Vancouver.
ILC6 in Vancouver
Abstract submission and registration are open:
ilc6vancouver.com
#immunosky #ILC6vancouver #ILC6
Lots of presenter spots available
Secure your spot and discounted fees during early bird registration and come visit beautiful Vancouver.
Reposted by Kat Mayer-Barber,PhD
This is a very appealing meeting in Paris later this year...
"The complexity of mycobacterial infections: from research to real-world impact"
#EMBOComplexInfections
#TBSky for the tuberculosis research, but also #NTM #Leprosy #IDSky #ImmunoSky
meetings.embo.org/event/26-myc...
"The complexity of mycobacterial infections: from research to real-world impact"
#EMBOComplexInfections
#TBSky for the tuberculosis research, but also #NTM #Leprosy #IDSky #ImmunoSky
meetings.embo.org/event/26-myc...
The complexity of mycobacterial infections: from research to real-world impact
Tuberculosis (TB), caused by Mycobacterium tuberculosis , remains one of the deadliest infectious diseases worldwide. Meanwhile, non-tuberculous mycobacteria (NTM) are an increasing global health co…
meetings.embo.org
January 15, 2026 at 11:34 PM
This is a very appealing meeting in Paris later this year...
"The complexity of mycobacterial infections: from research to real-world impact"
#EMBOComplexInfections
#TBSky for the tuberculosis research, but also #NTM #Leprosy #IDSky #ImmunoSky
meetings.embo.org/event/26-myc...
"The complexity of mycobacterial infections: from research to real-world impact"
#EMBOComplexInfections
#TBSky for the tuberculosis research, but also #NTM #Leprosy #IDSky #ImmunoSky
meetings.embo.org/event/26-myc...
Reposted by Kat Mayer-Barber,PhD
Important paper by Björn
Corleis. For decades a central tenet of #tuberculosis immunology has that IFNγ-driven iNOS expression in macrophages is the primary mechanism of bacterial control. Turns out this is really only in mice and maybe cattle. It’s not true in most species including humans an NHP.
Corleis. For decades a central tenet of #tuberculosis immunology has that IFNγ-driven iNOS expression in macrophages is the primary mechanism of bacterial control. Turns out this is really only in mice and maybe cattle. It’s not true in most species including humans an NHP.
Species-specific iNOS expression distinguishes epithelial and myeloid IFNγ responses in tuberculosis https://www.biorxiv.org/content/10.64898/2026.01.11.697682v1
January 16, 2026 at 12:52 AM
Important paper by Björn
Corleis. For decades a central tenet of #tuberculosis immunology has that IFNγ-driven iNOS expression in macrophages is the primary mechanism of bacterial control. Turns out this is really only in mice and maybe cattle. It’s not true in most species including humans an NHP.
Corleis. For decades a central tenet of #tuberculosis immunology has that IFNγ-driven iNOS expression in macrophages is the primary mechanism of bacterial control. Turns out this is really only in mice and maybe cattle. It’s not true in most species including humans an NHP.
Reposted by Kat Mayer-Barber,PhD
The Barber lab is looking to hire post-docs to work on #tuberculosis #immunology using murine and NHP models. BSL3 experience not required. Check out our lab in the NIH intramural program in Bethesda MD!
January 15, 2026 at 12:15 PM
The Barber lab is looking to hire post-docs to work on #tuberculosis #immunology using murine and NHP models. BSL3 experience not required. Check out our lab in the NIH intramural program in Bethesda MD!
Reposted by Kat Mayer-Barber,PhD
The @ragoninstitute.bsky.social is launching a new faculty search for a computational immunologist! Applications are open now and reviewed on a rolling basis. Please share broadly with your networks! #immunosky
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Computational Immunologist - Boston, Massachusetts (US) job with Ragon Institute of MGH, MIT, & Harvard | 12849577
The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard in Cambridge MA, together with the Departmen
www.nature.com
December 7, 2025 at 4:32 PM
The @ragoninstitute.bsky.social is launching a new faculty search for a computational immunologist! Applications are open now and reviewed on a rolling basis. Please share broadly with your networks! #immunosky
www.nature.com/naturecareer...
www.nature.com/naturecareer...
Reposted by Kat Mayer-Barber,PhD
Reposted by Kat Mayer-Barber,PhD
Check out our new paper with @nelson-lab.bsky.social. We used scRNAseq to profile the function of Mtb peptide-specific T cells from NHP and human lung granulomas. Beyond IFNγ, Mtb-specific T cells make a bunch of unexpected stuff, and human and NHP cell are really similar.
December 4, 2025 at 10:15 PM
Check out our new paper with @nelson-lab.bsky.social. We used scRNAseq to profile the function of Mtb peptide-specific T cells from NHP and human lung granulomas. Beyond IFNγ, Mtb-specific T cells make a bunch of unexpected stuff, and human and NHP cell are really similar.
Reposted by Kat Mayer-Barber,PhD
What we’ve got here is failure to communicate - some macrophages you just can’t reach!
Multiple features of granulomas limit effective T cell:MΦ interactions, posing a major barrier for vaccine-mediated protection.
Check out our new review!
onlinelibrary.wiley.com/doi/10.1111/...
Multiple features of granulomas limit effective T cell:MΦ interactions, posing a major barrier for vaccine-mediated protection.
Check out our new review!
onlinelibrary.wiley.com/doi/10.1111/...
<em>Journal of Internal Medicine</em> | Wiley Online Library
Tuberculosis (TB) remains a leading infectious cause of morbidity and mortality, and the development of a new, highly effective vaccine would have a tremendous beneficial impact on global health. Alt....
onlinelibrary.wiley.com
December 5, 2025 at 8:19 PM
What we’ve got here is failure to communicate - some macrophages you just can’t reach!
Multiple features of granulomas limit effective T cell:MΦ interactions, posing a major barrier for vaccine-mediated protection.
Check out our new review!
onlinelibrary.wiley.com/doi/10.1111/...
Multiple features of granulomas limit effective T cell:MΦ interactions, posing a major barrier for vaccine-mediated protection.
Check out our new review!
onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Kat Mayer-Barber,PhD
Job Alert
Junior Research Group Leader – Translation of Next Generation Anti-Cancer Cellular Immunotherapies
Deadline: 2026-01-07
Location: Germany, Mainz
👉 www.academiceurope.com/ads/junior-r...
#CancerResearch #DataScience #Immunology #MedicalScience #Medicine #PhD #leadershipskills #hiring
Junior Research Group Leader – Translation of Next Generation Anti-Cancer Cellular Immunotherapies
Deadline: 2026-01-07
Location: Germany, Mainz
👉 www.academiceurope.com/ads/junior-r...
#CancerResearch #DataScience #Immunology #MedicalScience #Medicine #PhD #leadershipskills #hiring
December 1, 2025 at 10:14 AM
Job Alert
Junior Research Group Leader – Translation of Next Generation Anti-Cancer Cellular Immunotherapies
Deadline: 2026-01-07
Location: Germany, Mainz
👉 www.academiceurope.com/ads/junior-r...
#CancerResearch #DataScience #Immunology #MedicalScience #Medicine #PhD #leadershipskills #hiring
Junior Research Group Leader – Translation of Next Generation Anti-Cancer Cellular Immunotherapies
Deadline: 2026-01-07
Location: Germany, Mainz
👉 www.academiceurope.com/ads/junior-r...
#CancerResearch #DataScience #Immunology #MedicalScience #Medicine #PhD #leadershipskills #hiring
Reposted by Kat Mayer-Barber,PhD
Splenic cDC1 efferocytosis and cross-presentation to CD8 T cells is promoted by GPR34 and lysophosphatidylserine, say Hanson Tam, Jason Cyster and colleagues: rupress.org/jem/article/...
#InnateImmunity #inflammation
@HHMI.org
#InnateImmunity #inflammation
@HHMI.org
November 17, 2025 at 2:30 PM
Splenic cDC1 efferocytosis and cross-presentation to CD8 T cells is promoted by GPR34 and lysophosphatidylserine, say Hanson Tam, Jason Cyster and colleagues: rupress.org/jem/article/...
#InnateImmunity #inflammation
@HHMI.org
#InnateImmunity #inflammation
@HHMI.org
Reposted by Kat Mayer-Barber,PhD
Assistant Professor position posted for my Department, Biological Sciences at UNC Charlotte! Current research foci: Immunology, Microbiology, Virology; Biomolecular Function; Proteostasis; Genome Integrity; Epigenome Regulation; Cancer; Environmental Risks. jobs.charlotte.edu/postings/65141
Assistant Professor
Applicants should possess a Ph.D. in the biological sciences or related fields.Candidates are expected to document expertise in their specialty by a record of postdoctoral training, peer reviewed publ...
jobs.charlotte.edu
November 19, 2025 at 2:16 PM
Assistant Professor position posted for my Department, Biological Sciences at UNC Charlotte! Current research foci: Immunology, Microbiology, Virology; Biomolecular Function; Proteostasis; Genome Integrity; Epigenome Regulation; Cancer; Environmental Risks. jobs.charlotte.edu/postings/65141
Reposted by Kat Mayer-Barber,PhD
if you are interested in a PhD in tuberculosis drug discovery, check out our opportunities 🧪🦠 #Tuberculosis lstm.ac/PhD
PhD opportunities
lstm.ac
November 24, 2025 at 3:18 PM
if you are interested in a PhD in tuberculosis drug discovery, check out our opportunities 🧪🦠 #Tuberculosis lstm.ac/PhD
Reposted by Kat Mayer-Barber,PhD
📢Are you a postdoctoral researcher with an excellent track record in #immunology and/or related field? We are hiring, but hurry, call closes 27 November! Apply and join us in Finland! Read more 👉 https://bit.ly/4r83ktP
#ImmunoSky #MedSky #LifeScience
#ImmunoSky #MedSky #LifeScience
November 21, 2025 at 8:48 AM
📢Are you a postdoctoral researcher with an excellent track record in #immunology and/or related field? We are hiring, but hurry, call closes 27 November! Apply and join us in Finland! Read more 👉 https://bit.ly/4r83ktP
#ImmunoSky #MedSky #LifeScience
#ImmunoSky #MedSky #LifeScience
Reposted by Kat Mayer-Barber,PhD
We have a last few chances to get your spot at #KSFUNGALPATH26 meeting next year! Submit your abstract by Dec 5 to be considered. Don't miss out!
#immunosky 🧪🍄
#immunosky 🧪🍄
Missed the short talk abstract deadline for Keystone Symposia on Fungal Pathogens? Last chance! Late-Breaking Abstracts are open until Dec 5, 11:59 PM MST. Submit now: hubs.ly/Q03TkWjd0
@therad-lab.bsky.social
#KSFungalPath26 #fungalpathogens #fungalinfection #pathogenesis
@therad-lab.bsky.social
#KSFungalPath26 #fungalpathogens #fungalinfection #pathogenesis
November 17, 2025 at 9:10 PM
We have a last few chances to get your spot at #KSFUNGALPATH26 meeting next year! Submit your abstract by Dec 5 to be considered. Don't miss out!
#immunosky 🧪🍄
#immunosky 🧪🍄
Reposted by Kat Mayer-Barber,PhD
How do cytokines shape immune cells?
We analyzed and visualized Parse Bio's 10M PBMC dataset to give researchers a powerful tool for exploring the dynamics between cytokines & peripheral blood mononuclear cells.
More: https://apps.allenimmunology.org/aifi/resources/parse-10m-cytokines/
#ImmunoSky
We analyzed and visualized Parse Bio's 10M PBMC dataset to give researchers a powerful tool for exploring the dynamics between cytokines & peripheral blood mononuclear cells.
More: https://apps.allenimmunology.org/aifi/resources/parse-10m-cytokines/
#ImmunoSky
November 21, 2025 at 3:57 PM
How do cytokines shape immune cells?
We analyzed and visualized Parse Bio's 10M PBMC dataset to give researchers a powerful tool for exploring the dynamics between cytokines & peripheral blood mononuclear cells.
More: https://apps.allenimmunology.org/aifi/resources/parse-10m-cytokines/
#ImmunoSky
We analyzed and visualized Parse Bio's 10M PBMC dataset to give researchers a powerful tool for exploring the dynamics between cytokines & peripheral blood mononuclear cells.
More: https://apps.allenimmunology.org/aifi/resources/parse-10m-cytokines/
#ImmunoSky
Reposted by Kat Mayer-Barber,PhD
#Immunosky people! 6th International Conference on Innate Lymphoid Cells - ILC6 in Vancouver.
ilc6vancouver.com
First program draft online. Abstract submission and registration officially open!
#ILC6 #ILC6Vancouver #2026ILC6
ilc6vancouver.com
First program draft online. Abstract submission and registration officially open!
#ILC6 #ILC6Vancouver #2026ILC6
November 21, 2025 at 10:03 PM
#Immunosky people! 6th International Conference on Innate Lymphoid Cells - ILC6 in Vancouver.
ilc6vancouver.com
First program draft online. Abstract submission and registration officially open!
#ILC6 #ILC6Vancouver #2026ILC6
ilc6vancouver.com
First program draft online. Abstract submission and registration officially open!
#ILC6 #ILC6Vancouver #2026ILC6
Reposted by Kat Mayer-Barber,PhD
This the lung micro environment regulates the macrophage glycocalyx via local cytokines at rest and following infection, a process likely crucial to viral infection
November 20, 2025 at 8:13 PM
This the lung micro environment regulates the macrophage glycocalyx via local cytokines at rest and following infection, a process likely crucial to viral infection
Reposted by Kat Mayer-Barber,PhD
Delighted to share our new pre-print from PhD student Ziyun Zhang joint with @tracyh9494.bsky.social demonstrating that lung alveolar macrophages have a dense glycocalyx and interstitial macrophages do not, @mcrcellmatrix.bsky.social @lydiabeckeriii.bsky.social www.biorxiv.org/content/10.1...
Airway macrophage specific expression of a dense glycocalyx and its remodelling following viral infection
The glycocalyx is best studied for its regulation of immune cell trafficking from the vasculature into inflamed tissues. The glycocalyx is composed of a range of glycans and glyco-proteins that form a...
www.biorxiv.org
November 20, 2025 at 8:13 PM
Delighted to share our new pre-print from PhD student Ziyun Zhang joint with @tracyh9494.bsky.social demonstrating that lung alveolar macrophages have a dense glycocalyx and interstitial macrophages do not, @mcrcellmatrix.bsky.social @lydiabeckeriii.bsky.social www.biorxiv.org/content/10.1...
Reposted by Kat Mayer-Barber,PhD
We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783
Apply - Interfolio
{{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
October 7, 2025 at 4:10 PM
We're hiring! Check out our ad and please re-post or forward to interested #Microbiology parties: apply.interfolio.com/174783
Reposted by Kat Mayer-Barber,PhD
#WeekendRead! #FriendOrFoes?! Zhang &co show @cp-immunity.bsky.social that herpes simplex virus #HSV1 exploits changes in membrane integrity to activate a GPI-anchored hydrolase which degrades cGAMP preventing #cGAS/#STING activation & favoring virus infection
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Membrane integrity changes upon viral infection activate sphingomyelinase SMPDL3B to restrict cGAS-STING signaling via cGAMP degradation
Wang et al. find that cell membrane stress upon viral infection induces expression
and stabilization of host sphingomyelin phosphodiesterase acid-like 3B (SMPDL3B),
which, in turn, degrades cGAMP to s...
www.cell.com
November 16, 2025 at 4:37 PM
#WeekendRead! #FriendOrFoes?! Zhang &co show @cp-immunity.bsky.social that herpes simplex virus #HSV1 exploits changes in membrane integrity to activate a GPI-anchored hydrolase which degrades cGAMP preventing #cGAS/#STING activation & favoring virus infection
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Reposted by Kat Mayer-Barber,PhD
#Openpositions #ImmunoSky #MedSky #wearehiring
Are you a postdoctoral researcher with an excellent track record in immunology research and/or a related field? Come and work with us in Finland!
👉Read more: bit.ly/43C68Fd
Are you a postdoctoral researcher with an excellent track record in immunology research and/or a related field? Come and work with us in Finland!
👉Read more: bit.ly/43C68Fd
October 27, 2025 at 7:25 AM
#Openpositions #ImmunoSky #MedSky #wearehiring
Are you a postdoctoral researcher with an excellent track record in immunology research and/or a related field? Come and work with us in Finland!
👉Read more: bit.ly/43C68Fd
Are you a postdoctoral researcher with an excellent track record in immunology research and/or a related field? Come and work with us in Finland!
👉Read more: bit.ly/43C68Fd
Reposted by Kat Mayer-Barber,PhD
NEW Perspective by @alazozcan.bsky.social, Tommaso Vicanolo, Veronique Angeli, Yuval Rinkevich & @drusqui.bsky.social presents a model of immune cells as architects of tissue barriers, by depositing matrix components or by interactions with structural cells and the ECM
#structuralimmunity #immunosky
#structuralimmunity #immunosky
Structural immunity: immune cells as architects of tissue barriers - Nature Reviews Immunology
This Perspective presents a framework of ‘structural immunity’ that positions immune cells as architects of tissue structure. Beyond their roles in antimicrobial defence, we posit that immune cells co...
www.nature.com
October 28, 2025 at 3:16 PM
NEW Perspective by @alazozcan.bsky.social, Tommaso Vicanolo, Veronique Angeli, Yuval Rinkevich & @drusqui.bsky.social presents a model of immune cells as architects of tissue barriers, by depositing matrix components or by interactions with structural cells and the ECM
#structuralimmunity #immunosky
#structuralimmunity #immunosky
Reposted by Kat Mayer-Barber,PhD
I was impressed with the meticulous work that Sarah did and how well she led a team of undergrads, rotation students, and the chemist collaborator, Abiodun Aderibigbe, who did the XPS analysis. There is more in the paper that I don't have time to capture here, please read the paper for more info!
Cold-water gut isolate from threespine stickleback (Gasterosteus aculeatus) reveals polypropylene surface oxidation and co-culture inhibition
Polyethylene terephthalate (PET) and polypropylene (PP), two of the most widely produced plastics in the United States, persist in cold-water environments where plastic-degrading microbes have been po...
www.biorxiv.org
October 23, 2025 at 8:29 PM
I was impressed with the meticulous work that Sarah did and how well she led a team of undergrads, rotation students, and the chemist collaborator, Abiodun Aderibigbe, who did the XPS analysis. There is more in the paper that I don't have time to capture here, please read the paper for more info!
Reposted by Kat Mayer-Barber,PhD
Ok, I have a minute, let's do this. Our lab is interested in contaminants found in Alaskan waters and identifying microbes from a fish native to Alaska, three-spine stickleback, to use in bioremediation in cold water lakes. Sarah was interested in microplastics, which I wasn't really studying. 1/n
I am so proud of @spasqualetti.bsky.social and this BioRxiv paper! I have to prep for class, but later today I'll highlight some of her findings about a stickleback gut isolate that can degrade plastic and other microbes that inhibit it's ability. 🦠🔬
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Cold-water gut isolate from threespine stickleback (Gasterosteus aculeatus) reveals polypropylene surface oxidation and co-culture inhibition
Polyethylene terephthalate (PET) and polypropylene (PP), two of the most widely produced plastics in the United States, persist in cold-water environments where plastic-degrading microbes have been po...
www.biorxiv.org
October 23, 2025 at 7:26 PM
Ok, I have a minute, let's do this. Our lab is interested in contaminants found in Alaskan waters and identifying microbes from a fish native to Alaska, three-spine stickleback, to use in bioremediation in cold water lakes. Sarah was interested in microplastics, which I wasn't really studying. 1/n