Marc Liesa
@marcliesa.bsky.social
Tenured Group Leader, Institut de Biologia Molecular de Barcelona, @csic.es. Previous Associate Professor at @uofcalifornia.bsky.social Los Angeles, Post Doc at @bostonu.bsky.social & PhD @ub.edu. https://t.co/bvx8gnppAW
Reposted by Marc Liesa
Extremely happy to see this out in @embojournal.org! Here we provide a guide on how to accurately determine mitochondrial membrane potential. Thanks to @marcliesa.bsky.social for the opportunity and to everyone involved! We hope you find it useful!
@ibmb-csic.bsky.social
@ibmb-csic.bsky.social
Measuring mitochondrial membrane potential
@marcliesa.bsky.social , Guillermo Martínez-Corrales et al @ibmb-csic.bsky.social comment on common misinterpretation of mitochondrial membrane potential measurements & suggest guidelines for accurate determination in cells
www.embopress.org/doi/full/10....
@marcliesa.bsky.social , Guillermo Martínez-Corrales et al @ibmb-csic.bsky.social comment on common misinterpretation of mitochondrial membrane potential measurements & suggest guidelines for accurate determination in cells
www.embopress.org/doi/full/10....
November 17, 2025 at 4:43 PM
Extremely happy to see this out in @embojournal.org! Here we provide a guide on how to accurately determine mitochondrial membrane potential. Thanks to @marcliesa.bsky.social for the opportunity and to everyone involved! We hope you find it useful!
@ibmb-csic.bsky.social
@ibmb-csic.bsky.social
Very happy with this comment out today! It was a fantastic teamwork effort, with invaluable input from the editor @embojournal.org and the reviewers. Thanks a lot to all involved! @csic.es @ibmb-csic.bsky.social
Measuring mitochondrial membrane potential
@marcliesa.bsky.social , Guillermo Martínez-Corrales et al @ibmb-csic.bsky.social comment on common misinterpretation of mitochondrial membrane potential measurements & suggest guidelines for accurate determination in cells
www.embopress.org/doi/full/10....
@marcliesa.bsky.social , Guillermo Martínez-Corrales et al @ibmb-csic.bsky.social comment on common misinterpretation of mitochondrial membrane potential measurements & suggest guidelines for accurate determination in cells
www.embopress.org/doi/full/10....
November 17, 2025 at 3:23 PM
Very happy with this comment out today! It was a fantastic teamwork effort, with invaluable input from the editor @embojournal.org and the reviewers. Thanks a lot to all involved! @csic.es @ibmb-csic.bsky.social
Reposted by Marc Liesa
Measuring mitochondrial membrane potential
@marcliesa.bsky.social , Guillermo Martínez-Corrales et al @ibmb-csic.bsky.social comment on common misinterpretation of mitochondrial membrane potential measurements & suggest guidelines for accurate determination in cells
www.embopress.org/doi/full/10....
@marcliesa.bsky.social , Guillermo Martínez-Corrales et al @ibmb-csic.bsky.social comment on common misinterpretation of mitochondrial membrane potential measurements & suggest guidelines for accurate determination in cells
www.embopress.org/doi/full/10....
November 17, 2025 at 2:28 PM
Measuring mitochondrial membrane potential
@marcliesa.bsky.social , Guillermo Martínez-Corrales et al @ibmb-csic.bsky.social comment on common misinterpretation of mitochondrial membrane potential measurements & suggest guidelines for accurate determination in cells
www.embopress.org/doi/full/10....
@marcliesa.bsky.social , Guillermo Martínez-Corrales et al @ibmb-csic.bsky.social comment on common misinterpretation of mitochondrial membrane potential measurements & suggest guidelines for accurate determination in cells
www.embopress.org/doi/full/10....
Reposted by Marc Liesa
Blocking extracellular glycine uptake mediated by GlyT1 mitigates protoporphyria
@marcliesa.bsky.social provides a Commentary on Ducamp et al. (buff.ly/W67oexo)
buff.ly/9TuVOy3
@marcliesa.bsky.social provides a Commentary on Ducamp et al. (buff.ly/W67oexo)
buff.ly/9TuVOy3
September 19, 2025 at 1:20 PM
Blocking extracellular glycine uptake mediated by GlyT1 mitigates protoporphyria
@marcliesa.bsky.social provides a Commentary on Ducamp et al. (buff.ly/W67oexo)
buff.ly/9TuVOy3
@marcliesa.bsky.social provides a Commentary on Ducamp et al. (buff.ly/W67oexo)
buff.ly/9TuVOy3
Thank you @jclinical-invest.bsky.social for inviting me to write a commentary about the original study published yesterday by Ducamp and colleagues, which shows a metabolic strategy to treat protoporphyrias. Commentary: www.jci.org/articles/vie.... Article: www.jci.org/articles/vie....
JCI -
Blocking extracellular glycine uptake mediated by GlyT1 mitigates protoporphyria
www.jci.org
September 17, 2025 at 2:17 PM
Thank you @jclinical-invest.bsky.social for inviting me to write a commentary about the original study published yesterday by Ducamp and colleagues, which shows a metabolic strategy to treat protoporphyrias. Commentary: www.jci.org/articles/vie.... Article: www.jci.org/articles/vie....
Reposted by Marc Liesa
Irene Hernando-Herráez, a researcher at the IBMB-CSIC, has been awarded a Starting Grant from the European Research Council (@erc.europa.eu), funded with €1.5 million. These prestigious grants support young scientists leading outstanding research projects. #ERCStG
September 4, 2025 at 10:36 AM
Irene Hernando-Herráez, a researcher at the IBMB-CSIC, has been awarded a Starting Grant from the European Research Council (@erc.europa.eu), funded with €1.5 million. These prestigious grants support young scientists leading outstanding research projects. #ERCStG
Reposted by Marc Liesa
🚨 Join us for the @faseborg.bsky.social
Meeting on Mechanisms of Mitochondrial DNA Mutation and Repair, June 1 - 5, 2025 | Nashville, Tennessee. 📅 Abstract submission & Early Registration close on April 20, 2025! Don't miss out: events.faseb.org/event/mitoch... Please re-post!
Meeting on Mechanisms of Mitochondrial DNA Mutation and Repair, June 1 - 5, 2025 | Nashville, Tennessee. 📅 Abstract submission & Early Registration close on April 20, 2025! Don't miss out: events.faseb.org/event/mitoch... Please re-post!
April 12, 2025 at 1:42 PM
🚨 Join us for the @faseborg.bsky.social
Meeting on Mechanisms of Mitochondrial DNA Mutation and Repair, June 1 - 5, 2025 | Nashville, Tennessee. 📅 Abstract submission & Early Registration close on April 20, 2025! Don't miss out: events.faseb.org/event/mitoch... Please re-post!
Meeting on Mechanisms of Mitochondrial DNA Mutation and Repair, June 1 - 5, 2025 | Nashville, Tennessee. 📅 Abstract submission & Early Registration close on April 20, 2025! Don't miss out: events.faseb.org/event/mitoch... Please re-post!
Reposted by Marc Liesa
We had an amazing time with the ABC family and already miss you all! Can’t wait to hear your exciting talks, have great discussions, and hit the slopes of the Alps again. #ABC2025
See you next time!🗻⛷️🚠🧬🧫🧪💙
See you next time!🗻⛷️🚠🧬🧫🧪💙
March 7, 2025 at 9:13 AM
We had an amazing time with the ABC family and already miss you all! Can’t wait to hear your exciting talks, have great discussions, and hit the slopes of the Alps again. #ABC2025
See you next time!🗻⛷️🚠🧬🧫🧪💙
See you next time!🗻⛷️🚠🧬🧫🧪💙
Reposted by Marc Liesa
Maria Zoghbi says she's in "ABC transporter heaven" at #ABC2025 🥰
A closer look at ABCB10 transporter dynamics may well keep you on cloud number nine... ☁️⭐️
A closer look at ABCB10 transporter dynamics may well keep you on cloud number nine... ☁️⭐️
March 1, 2025 at 10:00 AM
Maria Zoghbi says she's in "ABC transporter heaven" at #ABC2025 🥰
A closer look at ABCB10 transporter dynamics may well keep you on cloud number nine... ☁️⭐️
A closer look at ABCB10 transporter dynamics may well keep you on cloud number nine... ☁️⭐️
Reposted by Marc Liesa
Moving into mitochondria with Marc Liesa! ABCB10, heme and redox stress:
Some projects are literally a blood.bath... maybe sounds familiar to some other researchers out there? 😅🩸
Some projects are literally a blood.bath... maybe sounds familiar to some other researchers out there? 😅🩸
February 28, 2025 at 10:59 AM
Moving into mitochondria with Marc Liesa! ABCB10, heme and redox stress:
Some projects are literally a blood.bath... maybe sounds familiar to some other researchers out there? 😅🩸
Some projects are literally a blood.bath... maybe sounds familiar to some other researchers out there? 😅🩸
Reposted by Marc Liesa
Educació i innovació www.elpuntavui.cat/opinio/artic... @epons.bsky.social @jordivitria.bsky.social @pcb-ub.bsky.social @abadal.bsky.social @aristides-lopez.bsky.social @maricarmenb.bsky.social @kutandalkim.bsky.social @gaiaub.bsky.social @vcliments.bsky.social @marcliesa.bsky.social
Educació i innovació
Ha començat una nova legislatura. Hi ha un nou govern a Catalunya i s'esperen els nous equips dels departaments. Al mes d'agost i sense conèixer els equips que acompanyaran els consellers no es poden....
www.elpuntavui.cat
December 29, 2024 at 9:52 AM
Reposted by Marc Liesa
Preprint alert!! How zonated hepatocytes adapt to changes in lipid influx due to fasting or a Western diet (WD). We developed a microscopy-based phenotyping method called single-cell phenomics (scPhenomics) to measure the features of mitochondria and lipid droplets (LDs).
December 12, 2024 at 5:11 PM
Preprint alert!! How zonated hepatocytes adapt to changes in lipid influx due to fasting or a Western diet (WD). We developed a microscopy-based phenotyping method called single-cell phenomics (scPhenomics) to measure the features of mitochondria and lipid droplets (LDs).
Reposted by Marc Liesa
Join your fellow #ABC friends in the lecture hall and on the slopes for ABC2025 in Innsbruck Feb 27-Mar03!
Register abc2025meeting.org and see our invited speakers´list below! See you in Innsbruck!🧬⛰️🏂🧪
Register abc2025meeting.org and see our invited speakers´list below! See you in Innsbruck!🧬⛰️🏂🧪
December 2, 2024 at 6:03 PM
Join your fellow #ABC friends in the lecture hall and on the slopes for ABC2025 in Innsbruck Feb 27-Mar03!
Register abc2025meeting.org and see our invited speakers´list below! See you in Innsbruck!🧬⛰️🏂🧪
Register abc2025meeting.org and see our invited speakers´list below! See you in Innsbruck!🧬⛰️🏂🧪
Reposted by Marc Liesa
December 2, 2024 at 4:21 PM
Reposted by Marc Liesa
SHADES OF BLUE
Blue zones, supposed havens of longevity, have become a global brand. But skeptics think they rest on shaky science
www.science.org/content/arti...
Blue zones, supposed havens of longevity, have become a global brand. But skeptics think they rest on shaky science
www.science.org/content/arti...
Do ‘blue zones,’ supposed havens of longevity, rest on shaky science?
Critics say extraordinary life spans reflect faulty record keeping, not healthy lifestyles
www.science.org
November 26, 2024 at 7:31 AM
SHADES OF BLUE
Blue zones, supposed havens of longevity, have become a global brand. But skeptics think they rest on shaky science
www.science.org/content/arti...
Blue zones, supposed havens of longevity, have become a global brand. But skeptics think they rest on shaky science
www.science.org/content/arti...
Reposted by Marc Liesa
Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism
The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.
doi.org
November 25, 2024 at 11:16 AM
Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
Reposted by Marc Liesa
Do you know who Douglas Prasher is? Many don't, even though he is the person who cloned the original #GFP gene in the late 1980s. In my short history of plant light #microscopy I also cover a bit of his story - & why he is relatively unknown today, despite the importance of his work. See this 🧵👇
May 20, 2024 at 2:19 PM
Do you know who Douglas Prasher is? Many don't, even though he is the person who cloned the original #GFP gene in the late 1980s. In my short history of plant light #microscopy I also cover a bit of his story - & why he is relatively unknown today, despite the importance of his work. See this 🧵👇
Reposted by Marc Liesa
“The product of your education is not your thesis, it’s yourself“
@annarogers.bsky.social on why not to rely on LLM AI to write for you in graduate school. hackingsemantics.xyz/2024/writing/
@annarogers.bsky.social on why not to rely on LLM AI to write for you in graduate school. hackingsemantics.xyz/2024/writing/
On AI-assisted writing in graduate school
What is the proper role of AI ‘assistance’ in graduate student writing? It depends on what you mean by ‘graduate’.
hackingsemantics.xyz
November 17, 2024 at 2:56 PM
“The product of your education is not your thesis, it’s yourself“
@annarogers.bsky.social on why not to rely on LLM AI to write for you in graduate school. hackingsemantics.xyz/2024/writing/
@annarogers.bsky.social on why not to rely on LLM AI to write for you in graduate school. hackingsemantics.xyz/2024/writing/
2 days left to register and present a poster to the 10th MetNet meeting on mitochondria and metabolism. The final program with the selected short talks is now available. Looking forward to see you! @EMBO @IBMB_CSIC @IBUB_UB @IRBBarcelona @ciberdem @idibaps @VHIR_ @UABBarcelona
November 20, 2024 at 8:27 AM
2 days left to register and present a poster to the 10th MetNet meeting on mitochondria and metabolism. The final program with the selected short talks is now available. Looking forward to see you! @EMBO @IBMB_CSIC @IBUB_UB @IRBBarcelona @ciberdem @idibaps @VHIR_ @UABBarcelona
Deadline for registration to the Mitochondria and Metabolism meeting October 24-25th in Barcelona is soon! Sept 15 for oral presentation and Oct 3rd to secure your spot! With an @EMBO keynote lecture! Registration link:
November 20, 2024 at 8:27 AM
Deadline for registration to the Mitochondria and Metabolism meeting October 24-25th in Barcelona is soon! Sept 15 for oral presentation and Oct 3rd to secure your spot! With an @EMBO keynote lecture! Registration link:
Do not miss the most special Mitochondria Meeting in Barcelona, Oct 24-25th, with @OrianShirihai @GenoxphosLab @SWculek @FormentiniLaura @AlbertPol10 @QuintanaLab @mitodynamics @avlecvie @LabScorrano @AntonioZorzano ..., incl. short talks & posters. Registration & Program👇 .
November 20, 2024 at 8:27 AM
Do not miss the most special Mitochondria Meeting in Barcelona, Oct 24-25th, with @OrianShirihai @GenoxphosLab @SWculek @FormentiniLaura @AlbertPol10 @QuintanaLab @mitodynamics @avlecvie @LabScorrano @AntonioZorzano ..., incl. short talks & posters. Registration & Program👇 .
Highly motivated after the kick-off meeting with @CSIC colleagues and president @delPinoE for the preparation of a Science 4 Policy report about Metabolic Diseases, together with @DiabetesLabIBGM, María Monsalve, Angela M Valverde, María Angeles Martín and Yolanda Sanz.
November 20, 2024 at 8:27 AM
Highly motivated after the kick-off meeting with @CSIC colleagues and president @delPinoE for the preparation of a Science 4 Policy report about Metabolic Diseases, together with @DiabetesLabIBGM, María Monsalve, Angela M Valverde, María Angeles Martín and Yolanda Sanz.
Very excited with our new study just published in Redox Biology! We show that mitochondrial redox in hepatocytes determines the pro-inflammatory capacity of infiltrated neutrophils in alcohol-induced hepatitis.
November 20, 2024 at 8:27 AM
Very excited with our new study just published in Redox Biology! We show that mitochondrial redox in hepatocytes determines the pro-inflammatory capacity of infiltrated neutrophils in alcohol-induced hepatitis.
It is out! Here we describe a new method to isolate peridroplet mitochondria (PDM) from white adipose tissue (WAT), revealing unique functional characteristics in WAT PDM determined by lipid droplet size.
November 20, 2024 at 8:27 AM
It is out! Here we describe a new method to isolate peridroplet mitochondria (PDM) from white adipose tissue (WAT), revealing unique functional characteristics in WAT PDM determined by lipid droplet size.