Ewa Bomba-Warczak
@ebomba.bsky.social
Assistant Professor of Physiology at the University of Pennsylvania | studying long-lived mitochondrial proteins, organelle stability, mtDNA fidelity in neurons and oocytes
www.bombawarczaklab.com
www.bombawarczaklab.com
Reposted by Ewa Bomba-Warczak
Really thrilled to have our work on mitochondrial presequence strength out today @jcb.org. We establish quantitative parameters to better define "strong" and "weak" presequences both in vitro and in vivo. This work was spearheaded by the ever talented Youmian Yan, a BBSB graduate student in my lab.
Yan, @ianofbristol.bsky.social, @nieminm.bsky.social et al. define quantitative parameters underlying the strength of mitochondrial-targeting presequences, and demonstrate that yeast require strong presequences to facilitate select metabolic pathways in #mitochondria. rupress.org/jcb/article/...
January 8, 2026 at 5:47 PM
Really thrilled to have our work on mitochondrial presequence strength out today @jcb.org. We establish quantitative parameters to better define "strong" and "weak" presequences both in vitro and in vivo. This work was spearheaded by the ever talented Youmian Yan, a BBSB graduate student in my lab.
Reposted by Ewa Bomba-Warczak
In case you overloaded mitochondria and peroxisomes during your holidays, know that they are talking about it... and our speaker Peter Kim overheard the conversation.
This thursday, usual time and place. See you there?
This thursday, usual time and place. See you there?
January 6, 2026 at 5:23 PM
In case you overloaded mitochondria and peroxisomes during your holidays, know that they are talking about it... and our speaker Peter Kim overheard the conversation.
This thursday, usual time and place. See you there?
This thursday, usual time and place. See you there?
MITOchats are all about early career researchers and - of course - mitochondria! Join us tomorrow for three short talks delivered by Julia Riley @joulesriley.bsky.social, Eleonora Stronati, and Joan Blanco-Fernandez @joanblanco.bsky.social. See mitotalks.org for zoom link.
December 10, 2025 at 7:49 PM
MITOchats are all about early career researchers and - of course - mitochondria! Join us tomorrow for three short talks delivered by Julia Riley @joulesriley.bsky.social, Eleonora Stronati, and Joan Blanco-Fernandez @joanblanco.bsky.social. See mitotalks.org for zoom link.
See you all Thursday at MITOchats!! @mitotalks.bsky.social @mito-news.bsky.social @mitowomen.bsky.social @mitoworld.bsky.social
December 9, 2025 at 7:46 PM
See you all Thursday at MITOchats!! @mitotalks.bsky.social @mito-news.bsky.social @mitowomen.bsky.social @mitoworld.bsky.social
Reposted by Ewa Bomba-Warczak
the MITOscience of tomorrow is back.
December 9, 2025 at 9:53 AM
the MITOscience of tomorrow is back.
Reposted by Ewa Bomba-Warczak
Article out by @statnews.com profiling the terminated MOSAIC K99 program even though the goals fulfilled what the NIH says are their priorities: www.statnews.com/2025/12/08/t...
If you’re at #CellBio2025 coming to the MOSAIC scholar session today at 5:30pm in room 116!
If you’re at #CellBio2025 coming to the MOSAIC scholar session today at 5:30pm in room 116!
December 8, 2025 at 3:53 PM
Article out by @statnews.com profiling the terminated MOSAIC K99 program even though the goals fulfilled what the NIH says are their priorities: www.statnews.com/2025/12/08/t...
If you’re at #CellBio2025 coming to the MOSAIC scholar session today at 5:30pm in room 116!
If you’re at #CellBio2025 coming to the MOSAIC scholar session today at 5:30pm in room 116!
First group conference for the Bomba-Warczak lab #CellBio2025 in Philadelphia!
Come find us at poster session today - Molly Healey (P#0705) and tomorrow @tristanwrong.bsky.social (P#1257), and at the spotlight session on the now terminated NIH MOSAIC program tonight at 5:30pm.
Come find us at poster session today - Molly Healey (P#0705) and tomorrow @tristanwrong.bsky.social (P#1257), and at the spotlight session on the now terminated NIH MOSAIC program tonight at 5:30pm.
December 8, 2025 at 6:01 PM
First group conference for the Bomba-Warczak lab #CellBio2025 in Philadelphia!
Come find us at poster session today - Molly Healey (P#0705) and tomorrow @tristanwrong.bsky.social (P#1257), and at the spotlight session on the now terminated NIH MOSAIC program tonight at 5:30pm.
Come find us at poster session today - Molly Healey (P#0705) and tomorrow @tristanwrong.bsky.social (P#1257), and at the spotlight session on the now terminated NIH MOSAIC program tonight at 5:30pm.
Reposted by Ewa Bomba-Warczak
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
November 5, 2025 at 5:48 PM
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
Happy Halloween from the Barbie-Warczak lab 💪💅🎃 @tristanwrong.bsky.social
October 31, 2025 at 9:05 PM
Happy Halloween from the Barbie-Warczak lab 💪💅🎃 @tristanwrong.bsky.social
"Keeping mitochondria fit: Crosstalk between biogenesis and redox pathway" Happening now: link to join psu.zoom.us/j/95127917611
www.mitotalks.org
www.mitotalks.org
October 2, 2025 at 3:04 PM
"Keeping mitochondria fit: Crosstalk between biogenesis and redox pathway" Happening now: link to join psu.zoom.us/j/95127917611
www.mitotalks.org
www.mitotalks.org
Reposted by Ewa Bomba-Warczak
The future is visiting again! We are seeking applicants for the 7th season of MITOchats. Deadline for submission is October 17th. Visit www.mitotalks.org for details or submit your application at forms.gle/5D6vWE92yYCi...
September 25, 2025 at 9:59 PM
The future is visiting again! We are seeking applicants for the 7th season of MITOchats. Deadline for submission is October 17th. Visit www.mitotalks.org for details or submit your application at forms.gle/5D6vWE92yYCi...
Reposted by Ewa Bomba-Warczak
Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou
September 17, 2025 at 5:38 PM
Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations, Shannon Rhoads and team!🎉 t.co/BPxKlbU6Ou
Reposted by Ewa Bomba-Warczak
Hello world! Today’s officially the first day of the lab! It’s an empty space currently only filled with ideas (that I don’t have card access to yet 😂) but I’m excited for the science that will happen here! -JCG
September 2, 2025 at 10:52 PM
Hello world! Today’s officially the first day of the lab! It’s an empty space currently only filled with ideas (that I don’t have card access to yet 😂) but I’m excited for the science that will happen here! -JCG
Reposted by Ewa Bomba-Warczak
Very excited to share our latest work, “Mitochondrial presequences harbor variable strengths to maintain organellar function,” led by the fantastically talented @washubbsb.bsky.social graduate student Youmian Yan. A 🧵
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Mitochondrial presequences harbor variable strengths to maintain organellar function
Hundreds of mitochondrial-destined proteins rely on N-terminal presequences for organellar targeting and import. While generally described as positively charged amphipathic helices, presequences lack ...
www.biorxiv.org
May 29, 2025 at 9:18 PM
Very excited to share our latest work, “Mitochondrial presequences harbor variable strengths to maintain organellar function,” led by the fantastically talented @washubbsb.bsky.social graduate student Youmian Yan. A 🧵
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Ewa Bomba-Warczak
Congratulations to Drs. Lynch, Burslem, Marmorstein, Yi-Wei, and the entire research team on the publication of your latest research article in the newest issue of Science magazine! | Science www.science.org/doi/10.1126/...
Molecular basis of influenza ribonucleoprotein complex assembly and processive RNA synthesis
Influenza viruses replicate and transcribe their genome in the context of a conserved ribonucleoprotein (RNP) complex. By integrating cryo–electron microscopy single-particle analysis and cryo–electro...
www.science.org
May 15, 2025 at 6:46 PM
Congratulations to Drs. Lynch, Burslem, Marmorstein, Yi-Wei, and the entire research team on the publication of your latest research article in the newest issue of Science magazine! | Science www.science.org/doi/10.1126/...
Reposted by Ewa Bomba-Warczak
📢 New preprint alert!
We watch ATP, the energy currency, in tiny compartments of brain synapses to show that synapses talk to their local mitochondria to produce energy right when needed during plasticity, required for memory formation: www.biorxiv.org/content/10.1...
We watch ATP, the energy currency, in tiny compartments of brain synapses to show that synapses talk to their local mitochondria to produce energy right when needed during plasticity, required for memory formation: www.biorxiv.org/content/10.1...
April 10, 2025 at 5:10 PM
📢 New preprint alert!
We watch ATP, the energy currency, in tiny compartments of brain synapses to show that synapses talk to their local mitochondria to produce energy right when needed during plasticity, required for memory formation: www.biorxiv.org/content/10.1...
We watch ATP, the energy currency, in tiny compartments of brain synapses to show that synapses talk to their local mitochondria to produce energy right when needed during plasticity, required for memory formation: www.biorxiv.org/content/10.1...
Launching a new lab in today’s climate has been anything but smooth sailing—but today, we celebrate a major milestone! I’m absolutely thrilled to welcome not one, but two incredible graduate students to the lab! 🙌 Welcome Tristan and Molly!
www.bombawarczaklab.com/lab-members/
www.bombawarczaklab.com/lab-members/
May 20, 2025 at 9:59 PM
Launching a new lab in today’s climate has been anything but smooth sailing—but today, we celebrate a major milestone! I’m absolutely thrilled to welcome not one, but two incredible graduate students to the lab! 🙌 Welcome Tristan and Molly!
www.bombawarczaklab.com/lab-members/
www.bombawarczaklab.com/lab-members/
Reposted by Ewa Bomba-Warczak
Excited to see this out in @science.org today!! www.science.org/doi/10.1126/...
May 1, 2025 at 6:17 PM
Excited to see this out in @science.org today!! www.science.org/doi/10.1126/...
Reposted by Ewa Bomba-Warczak
My father-in-law, Jack Strominger, and I wrote a letter to the @wsj.com editor about the current threats to science due to Trump's funding freeze. Please repost! www.wsj.com/opinion/scie...
Opinion | Science Suffers With Trump’s Funding Freeze
America’s scientific enterprise demands reliable stewardship, not destabilizing political intervention.
www.wsj.com
April 21, 2025 at 6:21 PM
My father-in-law, Jack Strominger, and I wrote a letter to the @wsj.com editor about the current threats to science due to Trump's funding freeze. Please repost! www.wsj.com/opinion/scie...
Reposted by Ewa Bomba-Warczak
The Rutter Lab is attending ASBMB! If you are interested in cell metabolism, check out Jared, @queren-alcantara.bsky.social and @luisci22.bsky.social research talks in the sessions below. See you in Chicago! @hhmi.org @uofubiochem.bsky.social @bwfund.bsky.social @cziscience.bsky.social
April 8, 2025 at 12:07 AM
The Rutter Lab is attending ASBMB! If you are interested in cell metabolism, check out Jared, @queren-alcantara.bsky.social and @luisci22.bsky.social research talks in the sessions below. See you in Chicago! @hhmi.org @uofubiochem.bsky.social @bwfund.bsky.social @cziscience.bsky.social
Reposted by Ewa Bomba-Warczak
My quote of the day
"Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less."
Maria Salomea Skłodowska-Curie (Marie Curie)
First female Nobelist, 1st person to win 2 Nobels, and only person to win Nobels in 2 scientific fields.
"Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less."
Maria Salomea Skłodowska-Curie (Marie Curie)
First female Nobelist, 1st person to win 2 Nobels, and only person to win Nobels in 2 scientific fields.
April 6, 2025 at 5:09 PM
My quote of the day
"Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less."
Maria Salomea Skłodowska-Curie (Marie Curie)
First female Nobelist, 1st person to win 2 Nobels, and only person to win Nobels in 2 scientific fields.
"Nothing in life is to be feared, it is only to be understood. Now is the time to understand more, so that we may fear less."
Maria Salomea Skłodowska-Curie (Marie Curie)
First female Nobelist, 1st person to win 2 Nobels, and only person to win Nobels in 2 scientific fields.
Reposted by Ewa Bomba-Warczak
Thrilled to announce that the registration for the EMBO workshop „Mitochondria in the Nervous System“ is now open.
Join us from Sep 29th to Oct 2nd in beautiful Engelberg, Switzerland!
meetings.embo.org/event/25-mit...
Join us from Sep 29th to Oct 2nd in beautiful Engelberg, Switzerland!
meetings.embo.org/event/25-mit...
Mitochondria in the Nervous System
The brain is a high energy-demanding tissue with an heterogenous cellular composition. Most of the energy consumed is used for maintenance of neuronal synaptic transmission, and neurons almost exclus…
meetings.embo.org
April 4, 2025 at 1:44 PM
Thrilled to announce that the registration for the EMBO workshop „Mitochondria in the Nervous System“ is now open.
Join us from Sep 29th to Oct 2nd in beautiful Engelberg, Switzerland!
meetings.embo.org/event/25-mit...
Join us from Sep 29th to Oct 2nd in beautiful Engelberg, Switzerland!
meetings.embo.org/event/25-mit...
Reposted by Ewa Bomba-Warczak
NIH MOSAIC program’s termination is a massive loss for the next generation of scientists, threatening the research workforce’s future and human health. We remain committed to supporting MOSAIC Scholars with critical resources for the remainder of the award and beyond. Full statement: buff.ly/TSMrvXq
April 4, 2025 at 7:48 PM
NIH MOSAIC program’s termination is a massive loss for the next generation of scientists, threatening the research workforce’s future and human health. We remain committed to supporting MOSAIC Scholars with critical resources for the remainder of the award and beyond. Full statement: buff.ly/TSMrvXq
Reposted by Ewa Bomba-Warczak
The termination of the NIH MOSAIC program is a critical loss. As one of the 5 societies supporting MOSAIC scholars, ASCB remains dedicated to supporting early-career scientists & broadening the biomedical workforce. We'll continue our mentorship & development efforts through the end of the grant.
ASCB Responds to the NIH’s Termination of the MOSAIC Program - ASCB
As one of the five scientific societies funded to provide professional development support through the NIH Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) program, th...
www.ascb.org
April 3, 2025 at 4:56 PM
The termination of the NIH MOSAIC program is a critical loss. As one of the 5 societies supporting MOSAIC scholars, ASCB remains dedicated to supporting early-career scientists & broadening the biomedical workforce. We'll continue our mentorship & development efforts through the end of the grant.