Blame declining confidence, a lack of convenience and rising complacency

One of Sweden’s most delicious exports, Jansson’s temptation, otherwise known as Janssons frestelse, is a creamy potato casserole with melty onions and umami-packed tinned sprats (see Tip) There are a few theories as to the origin of this Swedish classic, which is often served with schnapps as part of the Julbord, or Christmas table One suggests that it was named after a 1928 silent film, while an older story says that it was named after the opera singer Per Adolf Janzon — but that one’s “not so likely” according to Jens Linder, a Swedish food writer

Scientific discovery relies on innovative software as much as experimental methods, especially in proteomics, where computational tools are essential for mass spectrometer setup, data analysis, and interpretation. Since the introduction of SEQUEST, proteomics software has grown into a complex ecosystem of algorithms, predictive models, and workflows, but the field faces challenges, including the increasing complexity of mass spectrometry data, limited reproducibility due to proprietary software, and difficulties integrating with other omics disciplines. Closed-source, platform-specific tools exacerbate these issues by restricting innovation, creating inefficiencies, and imposing hidden costs on the community. Open-source software (OSS), aligned with the FAIR Principles (Findable, Accessible, Interoperable, Reusable), offers a solution by promoting transparency, reproducibility, and community-driven development, which fosters collaboration and continuous improvement. In this manuscript, we explore the role of OSS in computational proteomics, its alignment with FAIR principles, and its potential to address challenges related to licensing, distribution, and standardization. Drawing on lessons from other omics fields, we present a vision for a future where OSS and FAIR principles underpin a transparent, accessible, and innovative proteomics community.

At Stockholm University the Department of Biochemistry and Biophysics (DBB) and the Department of Molecular Biosciences, The Wenner-Gren Institute (MBW) are looking to fill one position as DDLS fellow

Join leading scientists at Nordic MSP 2025 at ODEON in Odense, Denmark. A premier conference on mass spectrometry and proteomics.

imageimagehu.MAP3.0 integrates mass spectrometry experiments to identify human protein complexes. Using this resource, this study characterizes covariation of complexes, identifies mutually exclusive ...

Mass spectrometry is the dominant technology in the field of proteomics, enabling high-throughput analysis of the protein content of complex biological samples. Due to the complexity of the instrument...

We are looking for a motivated PhD student to join us in a unique, collaborative project between our Affinity Ligand Design team at Cytiva and the Elofsson group at Stockholm University, where we will...

Proteins are the building blocks of life. They build our cells, send signals and transport substances. But they will only work correctly if they attain their exact 3-dimensional form. Gunnar von Heijn...

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