Arne Elofsson
bioinfo.se
Arne Elofsson
@bioinfo.se
Professor in bioinformatics, Stockholm University. Protein structure lover ( interactions predictions, evolution ..). Using machine learning as a part of AI for Sciences for halv my life. In addition to succén, I sometimes rants about sailing or skiing.
Reposted by Arne Elofsson
Isomorphic Labs said IsoDDE, a drug-design system, more than doubles AlphaFold 3's accuracy on the Runs N Poses benchmark and outperforms AlphaFold 3 by 2.3x on antibody–antigen DockQ>0.8 tests.
The Isomorphic Labs Drug Design Engine unlocks a new frontier beyond AlphaFold - Isomorphic Labs
Today, we are excited to share an update on our progress towards a new frontier of drug design. We have unlocked a new paradigm of predictive accuracy in understanding our biomolecular world, allowing...
www.isomorphiclabs.com
February 11, 2026 at 1:15 PM
Reposted by Arne Elofsson
Isomorphic Labs Drug Design Engine (IsoDDE), a unified computational drug-design system

Announcement:
www.isomorphiclabs.com/articles/the...

Report:
storage.googleapis.com/isomorphicla...
February 10, 2026 at 3:16 PM
What has changed in 20 years
February 10, 2026 at 6:30 AM
Reposted by Arne Elofsson
Dinosaurs And Non-Dinosaurs

xkcd.com/3204/
February 9, 2026 at 9:10 PM
Reposted by Arne Elofsson
New preprint with work led by @asrauh.bsky.social in which we explore how double mutant cycles could be used to study molecular interactions in condensates, and highlight difficulties in extracting information about interactions from mutational experiments

www.biorxiv.org/content/10.6...
February 5, 2026 at 9:54 PM
Reposted by Arne Elofsson
I am remiss for pointing out that Jesse @j-my-sci.bsky.social highlights sharing, explainable code, and testing in his paper. These weren’t points he missed, just things I wanted to expound on or highlight (including my TopHat2 typo).

pubs.acs.org/doi/10.1021/...

8/7
Vibe Coding Omics Data Analysis Applications
Building custom data analysis platforms has traditionally required extensive software engineering expertise, limiting access for many researchers. Here, I demonstrate that modern large language models...
pubs.acs.org
January 31, 2026 at 12:05 PM
Reposted by Arne Elofsson
I just released v1.4 + v1.5 of "mkdocs-quiz" this week with some fun new features:

✍️ Fill-in-the-blank quizzes (not just multiple choice)
💾 QTI export for Canvas/Blackboard/Moodle
✨ Interactive terminal CLI quiz runner

github.com/ewels/mkdocs-quiz
January 29, 2026 at 11:14 AM
Reposted by Arne Elofsson
Double-Pronged Extension Cord

xkcd.com/3198/
January 28, 2026 at 3:30 AM
Reposted by Arne Elofsson
Nobody has caused more damage to the US in one single year than Donald Trump:
1. He has abolished the rule of law.
2. He has made the US more corrupt to his benefit than ever.
3. He promotes extreme crony capitalism.
4. He has sharply cut science financing. /1
January 28, 2026 at 3:45 AM
Reposted by Arne Elofsson
Holy shit, there's an open carry #2A protest of ICE happening in Douglas County Colorado -- a very wealthy and very red suburb county of Denver. (I lived there for 16 years.) The Trump Administration pissing off committed gun owners sufficiently for them to join the protests against ICE is wild.
January 28, 2026 at 1:59 AM
Reposted by Arne Elofsson
My hero!!! An amazing scientist and a wonderful person!
Jane Richardson was born #OTD in 1941

+ Developed the Richardson (ribbon) diagram to represent proteins' 3D structure (becoming a standard representation for protein structures)
+ MacArthur Fellow, 1985
+ Elected, Nat'l Academy of Sciences, 1991
+ President, Biophysical Society, 2012

#WomenInSTEM
January 28, 2026 at 12:56 AM
Reposted by Arne Elofsson
Well, I have been hooked on Apple products for many many many years. No longer. I am going to start figuring out how to detach myself from them. #BoycottApple
January 26, 2026 at 4:15 PM
Reposted by Arne Elofsson
Once a vatnik, always vatnik.
January 24, 2026 at 8:36 PM
Reposted by Arne Elofsson
Medan Ukraina fortsätter att utveckla sin utrikes underrättelsetjänst mot krigets krav, så går vi motsatt väg. Karta och verklighet. Så svårt.
Ukraine to Develop Foreign Intelligence Service Combat Units for Operations Abroad - Militarnyi
Ukraine will develop units of the Foreign Intelligence Service to carry out operations necessary to protect the country's interests abroad.
militarnyi.com
January 25, 2026 at 9:14 AM
Cost Savings xkcd.com/3197/
Cost Savings
xkcd.com
January 22, 2026 at 1:41 PM
Reposted by Arne Elofsson
Excellent overview of the (mind-blowing) effects of the Shingles vaccine against dementia by @erictopol.bsky.social Ground Truth 🧪 "Two new studies add to a remarkable body of evidence for benefit" ⬇️

open.substack.com/pub/erictopo...
Spotlight on the Shingles Vaccine—Again!
Two new studies add to a remarkable body of evidence for benefit
open.substack.com
January 22, 2026 at 7:39 AM
Reposted by Arne Elofsson
Trump’s Board of Peace logo is basically the UN logo, except dipped in gold and edited so the world only includes America.
January 22, 2026 at 10:16 AM
Reposted by Arne Elofsson
European leaders must stop appeasing Trump. There can be no more appeasement. I am sick of it and I am confident many other European citizens are too. We must keep our dignity, our pride, our strength, our self respect - otherwise our lives become meaningless.
January 20, 2026 at 9:09 PM
Reposted by Arne Elofsson
My time in @martinsteinegger.bsky.social's group is ending, but I’m staying in Korea to build a lab at Sungkyunkwan University School of Medicine. If you or someone you know is interested in molecular machine learning and open-source bioinformatics, please reach out. I am hiring!
mirdita.org
Mirdita Lab - Laboratory for Computational Biology & Molecular Machine Learning
Mirdita Lab builds scalable bioinformatics methods.
mirdita.org
January 20, 2026 at 11:07 AM
Reposted by Arne Elofsson
"Danish pension fund AkademikerPension announces they will sell all US Treasuries by month-end, citing "rising credit risk" under President Trump."
January 20, 2026 at 4:29 PM