UW Genome Sciences
@uwgenome.bsky.social
The Department of Genome Sciences at The University of Washington
Congratulations to Bill Noble on receiving the 2026 Gil Omenn Computational Proteomics Award from US HUPO!
us-hupo.org/Computationa...
us-hupo.org/Computationa...
US HUPO - Computational Proteomics Award
us-hupo.org
November 12, 2025 at 5:14 PM
Congratulations to Bill Noble on receiving the 2026 Gil Omenn Computational Proteomics Award from US HUPO!
us-hupo.org/Computationa...
us-hupo.org/Computationa...
Congratulations to Mike MacCoss on receiving the Donald F. Hunt Distinguished Contribution in Proteomics Award from US HUPO!
us-hupo.org/Distinguishe...
us-hupo.org/Distinguishe...
US HUPO - Distinguished Contribution Award
us-hupo.org
November 12, 2025 at 5:12 PM
Congratulations to Mike MacCoss on receiving the Donald F. Hunt Distinguished Contribution in Proteomics Award from US HUPO!
us-hupo.org/Distinguishe...
us-hupo.org/Distinguishe...
Congratulations to Winston Dredge on being awarded a WRF Postdoctoral Fellowship!
November 2, 2025 at 9:12 PM
Congratulations to Winston Dredge on being awarded a WRF Postdoctoral Fellowship!
Jay Shendure elected to National Academy of Medicine
newsroom.uw.edu/blog/jay-she...
newsroom.uw.edu/blog/jay-she...
Jay Shendure elected to National Academy of Medicine - UW Medicine | Newsroom
newsroom.uw.edu
October 28, 2025 at 3:17 PM
Jay Shendure elected to National Academy of Medicine
newsroom.uw.edu/blog/jay-she...
newsroom.uw.edu/blog/jay-she...
CellCover Defines Marker Gene Panels Capturing Developmental Progression in Neocortical Neural Stem Cell Identity
elifesciences.org/reviewed-pre...
elifesciences.org/reviewed-pre...
elifesciences.org
October 22, 2025 at 11:07 PM
CellCover Defines Marker Gene Panels Capturing Developmental Progression in Neocortical Neural Stem Cell Identity
elifesciences.org/reviewed-pre...
elifesciences.org/reviewed-pre...
Mechanisms underlying thermally induced growth plasticity in juvenile Pacific halibut
journals.biologists.com/jeb/article/...
journals.biologists.com/jeb/article/...
October 6, 2025 at 5:55 PM
Mechanisms underlying thermally induced growth plasticity in juvenile Pacific halibut
journals.biologists.com/jeb/article/...
journals.biologists.com/jeb/article/...
Epithelial competition determines gene therapy potential to suppress Fanconi Anemia oral cancer risk
journals.plos.org/ploscompbiol...
journals.plos.org/ploscompbiol...
Epithelial competition determines gene therapy potential to suppress Fanconi Anemia oral cancer risk
Author summary We investigated factors influencing the success of oral mucosal gene therapy for Fanconi Anemia (FA), a genetic syndrome marked by DNA repair defects in conjunction with a heightened ri...
journals.plos.org
September 23, 2025 at 11:14 PM
Epithelial competition determines gene therapy potential to suppress Fanconi Anemia oral cancer risk
journals.plos.org/ploscompbiol...
journals.plos.org/ploscompbiol...
Registration is now open for the Mutational Scanning Symposium!!
25-27 March 2026
Melbourne, Australia
Matt Hurles (Wellcome Sanger) and Maitreya Dunham (University of Washington)
Deadline for abstract submissions: 2 November 2025.
www.mss2026.org
25-27 March 2026
Melbourne, Australia
Matt Hurles (Wellcome Sanger) and Maitreya Dunham (University of Washington)
Deadline for abstract submissions: 2 November 2025.
www.mss2026.org
MSS26
Mutational Scanning Symposium 2026, 25-27 March, Melbourne
www.mss2026.org
September 18, 2025 at 8:41 PM
Registration is now open for the Mutational Scanning Symposium!!
25-27 March 2026
Melbourne, Australia
Matt Hurles (Wellcome Sanger) and Maitreya Dunham (University of Washington)
Deadline for abstract submissions: 2 November 2025.
www.mss2026.org
25-27 March 2026
Melbourne, Australia
Matt Hurles (Wellcome Sanger) and Maitreya Dunham (University of Washington)
Deadline for abstract submissions: 2 November 2025.
www.mss2026.org
Reposted by UW Genome Sciences
🧬 How fast do humans mutate?
Our groundbreaking study tracks DNA changes across 4 generations to reveal the pace of human evolution revealing insights into our genetic legacy. Watch now 👉 youtu.be/6TTCZdZd4Y4
#Genetics #Evolution #ScienceVideo #Nature @hhmi.org @uwgenome.bsky.social
Our groundbreaking study tracks DNA changes across 4 generations to reveal the pace of human evolution revealing insights into our genetic legacy. Watch now 👉 youtu.be/6TTCZdZd4Y4
#Genetics #Evolution #ScienceVideo #Nature @hhmi.org @uwgenome.bsky.social
How quickly do humans mutate? Four generations help answer the question
YouTube video by nature video
youtu.be
September 8, 2025 at 8:56 PM
🧬 How fast do humans mutate?
Our groundbreaking study tracks DNA changes across 4 generations to reveal the pace of human evolution revealing insights into our genetic legacy. Watch now 👉 youtu.be/6TTCZdZd4Y4
#Genetics #Evolution #ScienceVideo #Nature @hhmi.org @uwgenome.bsky.social
Our groundbreaking study tracks DNA changes across 4 generations to reveal the pace of human evolution revealing insights into our genetic legacy. Watch now 👉 youtu.be/6TTCZdZd4Y4
#Genetics #Evolution #ScienceVideo #Nature @hhmi.org @uwgenome.bsky.social
Congratulations to Zukai Liu and Bria Metzger on being awarded Parker Travel Awards for best poster at the 2025 department retreat!
September 14, 2025 at 9:22 PM
Congratulations to Zukai Liu and Bria Metzger on being awarded Parker Travel Awards for best poster at the 2025 department retreat!
Multiplex and multimodal mapping of variant effects in secreted proteins via MultiSTEP
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Multiplex and multimodal mapping of variant effects in secreted proteins via MultiSTEP - Nature Structural & Molecular Biology
Multiplexed assays of variant effect can resolve clinical variants but are incompatible with secreted proteins. Here Popp et al. develop MultiSTEP, a generalizable surface-tethering method to assess v...
www.nature.com
September 10, 2025 at 3:55 AM
Multiplex and multimodal mapping of variant effects in secreted proteins via MultiSTEP
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Congratulations to Olivia Waltner on being awarded the Bonita and David Brewer Fellowship!
September 2, 2025 at 5:51 PM
Congratulations to Olivia Waltner on being awarded the Bonita and David Brewer Fellowship!
Lineage-resolved analysis of embryonic gene expression evolution in C. elegans and C. briggsae
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Lineage-resolved analysis of embryonic gene expression evolution in C. elegans and C. briggsae
The constraints that govern the evolution of gene expression patterns across development remain unclear. Single-cell RNA sequencing can detail these constraints by systematically profiling homologous ...
www.science.org
August 21, 2025 at 5:13 PM
Lineage-resolved analysis of embryonic gene expression evolution in C. elegans and C. briggsae
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Accelerating Biomolecular Modeling with AtomWorks and RF3
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Accelerating Biomolecular Modeling with AtomWorks and RF3
Deep learning methods trained on protein structure databases have revolutionized biomolecular structure prediction, but developing and training new models remains a considerable challenge. To facilita...
www.biorxiv.org
August 20, 2025 at 10:56 PM
Accelerating Biomolecular Modeling with AtomWorks and RF3
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Congratulations to Jenny Nathans on being awarded an NRSA Fellowship!
August 4, 2025 at 9:06 PM
Congratulations to Jenny Nathans on being awarded an NRSA Fellowship!
Congratulations to Caleb Carr on being awarded an NRSA Fellowship!
July 28, 2025 at 4:11 PM
Congratulations to Caleb Carr on being awarded an NRSA Fellowship!
Complex genetic variation in nearly complete human genomes
pubmed.ncbi.nlm.nih.gov/40702183/
pubmed.ncbi.nlm.nih.gov/40702183/
Complex genetic variation in nearly complete human genomes - PubMed
Diverse sets of complete human genomes are required to construct a pangenome reference and to understand the extent of complex structural variation. Here we sequence 65 diverse human genomes and build...
pubmed.ncbi.nlm.nih.gov
July 24, 2025 at 2:49 PM
Complex genetic variation in nearly complete human genomes
pubmed.ncbi.nlm.nih.gov/40702183/
pubmed.ncbi.nlm.nih.gov/40702183/
Reposted by UW Genome Sciences
Using >130 human & 12 primate haplotypes, we reconstruct the chromosome 22q11.2 evolution to identify haplotype structures linked to deletions or inversions, explaining the lower prevalence of 22q11.2 deletion syndrome in individuals of African descent. @hhmi.org @uwgenome.bsky.social
July 8, 2025 at 6:30 PM
Using >130 human & 12 primate haplotypes, we reconstruct the chromosome 22q11.2 evolution to identify haplotype structures linked to deletions or inversions, explaining the lower prevalence of 22q11.2 deletion syndrome in individuals of African descent. @hhmi.org @uwgenome.bsky.social
Congratulations to Maggie Russell on receiving the UW Graduate School's Distinguished Dissertation Award!
July 3, 2025 at 9:25 PM
Congratulations to Maggie Russell on receiving the UW Graduate School's Distinguished Dissertation Award!
Congratulations to Leah Anderson on winning the best talk award at the Pacific Northwest Yeast Club meeting!
www.pnwyc.net
www.pnwyc.net
PNWYC
PNWYC 2025 Meeting
A day for yeast labs in the Pacific Northwest to get together and share research, outreach, teaching, and more!
June 20th, 2025, in Vancouver, Canada
Michael Smith Laboratories, Uni...
www.pnwyc.net
July 2, 2025 at 6:35 PM
Congratulations to Leah Anderson on winning the best talk award at the Pacific Northwest Yeast Club meeting!
www.pnwyc.net
www.pnwyc.net
Congratulations to Alison Feder on receiving the SMBE 2025 Early-Career Excellence Award!
members.smbe.org/news/Details...
members.smbe.org/news/Details...
SMBE 2025 Faculty Award Winners
SMBE is delighted to announce our 2025 Faculty Award Winners!
Early-Career Excellence Award winner: Alison Feder
Alison Feder is an Assistant Professor of Genome Sciences at the University of Washingt...
members.smbe.org
June 27, 2025 at 5:38 PM
Congratulations to Alison Feder on receiving the SMBE 2025 Early-Career Excellence Award!
members.smbe.org/news/Details...
members.smbe.org/news/Details...
Congratulations to Leah Anderson and Elliott Swanson on receiving the Sonia Ting Travel Award!
June 27, 2025 at 4:32 PM
Congratulations to Leah Anderson and Elliott Swanson on receiving the Sonia Ting Travel Award!
Gene clusters linked to insulin resistance identified in a genome-wide study of the Taiwan Biobank population
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Gene clusters linked to insulin resistance identified in a genome-wide study of the Taiwan Biobank population - Nature Communications
Understanding genetic drivers of insulin resistance is crucial for addressing metabolic disorders. Here, the authors show associations involving GCKR, MLXIPL, APOA5, and APOC1, highlighting adipose ti...
www.nature.com
May 22, 2025 at 6:31 PM
Gene clusters linked to insulin resistance identified in a genome-wide study of the Taiwan Biobank population
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Harmful algal blooms are preceded by a predictable and quantifiable shift in the oceanic microbiome
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Harmful algal blooms are preceded by a predictable and quantifiable shift in the oceanic microbiome - Nature Communications
Harmful algal blooms (HABs) pose negative worldwide impacts that could be minimized through the development of a forecasting tool. Quantitative analysis of peptides produced by a coastal microbiome pr...
www.nature.com
May 21, 2025 at 10:27 PM
Harmful algal blooms are preceded by a predictable and quantifiable shift in the oceanic microbiome
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Population size interacts with reproductive longevity to shape the germline mutation rate
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
May 20, 2025 at 5:59 PM
Population size interacts with reproductive longevity to shape the germline mutation rate
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...