KingFranklinIV
@kingfrankliniv.bsky.social
Psychiatrist/Instructor, Mass General Hospital/Harvard Medical School | antireductionist, subjective experience, psychedelics | my views
Pinned
Happy to share that my group's new paper, "Psychedelic-assisted Therapy as a Promising Treatment for Irritable Bowel Syndrome", building on exciting cross-disciplinary work at Mass General Hospital, is now published in the Journal of Clinical Gastroenterology:
pubmed.ncbi.nlm.nih.gov/39998940/
pubmed.ncbi.nlm.nih.gov/39998940/
Reposted by KingFranklinIV
BREAKING: Czech Republic Set to Allow Medical Use of Psilocybin
If approved by the Senate next month, it will become the third country in the world to allow access to a psychedelic ahead of conventional marketing approval.
If approved by the Senate next month, it will become the third country in the world to allow access to a psychedelic ahead of conventional marketing approval.
May 31, 2025 at 5:20 PM
BREAKING: Czech Republic Set to Allow Medical Use of Psilocybin
If approved by the Senate next month, it will become the third country in the world to allow access to a psychedelic ahead of conventional marketing approval.
If approved by the Senate next month, it will become the third country in the world to allow access to a psychedelic ahead of conventional marketing approval.
Reposted by KingFranklinIV
Just when you thought it couldn't possibly get any worse.
May 18, 2025 at 4:52 PM
Just when you thought it couldn't possibly get any worse.
Reposted by KingFranklinIV
Participate in the Global Psychedelic Survey 2025 (GPS 2025), a large global study on psychedelic use.
Sponsored by Uni of Michigan, closes May 16!
Win 1 of 15 $100 Amazon gift cards.
Take part: bit.ly/GPS2025-survey
#GPS2025 #PsychedelicResearch #GlobalSurvey
Sponsored by Uni of Michigan, closes May 16!
Win 1 of 15 $100 Amazon gift cards.
Take part: bit.ly/GPS2025-survey
#GPS2025 #PsychedelicResearch #GlobalSurvey
May 11, 2025 at 11:25 PM
Participate in the Global Psychedelic Survey 2025 (GPS 2025), a large global study on psychedelic use.
Sponsored by Uni of Michigan, closes May 16!
Win 1 of 15 $100 Amazon gift cards.
Take part: bit.ly/GPS2025-survey
#GPS2025 #PsychedelicResearch #GlobalSurvey
Sponsored by Uni of Michigan, closes May 16!
Win 1 of 15 $100 Amazon gift cards.
Take part: bit.ly/GPS2025-survey
#GPS2025 #PsychedelicResearch #GlobalSurvey
Reposted by KingFranklinIV
Quite a nice image of 5-HT2A receptor distribution by Blake in the lab using our mice (I think now at JAX)
pubmed.ncbi.nlm.nih.gov/37808655/
pubmed.ncbi.nlm.nih.gov/37808655/
May 8, 2025 at 7:27 PM
Quite a nice image of 5-HT2A receptor distribution by Blake in the lab using our mice (I think now at JAX)
pubmed.ncbi.nlm.nih.gov/37808655/
pubmed.ncbi.nlm.nih.gov/37808655/
Reposted by KingFranklinIV
Huge thanks to friends at @imperialcollegeldn.bsky.social
and @schoolofppls.bsky.social for hosting me and sparking some great discussions on psychedelics, well-being, and more.
(I promise I have more than one outfit)
and @schoolofppls.bsky.social for hosting me and sparking some great discussions on psychedelics, well-being, and more.
(I promise I have more than one outfit)
CPCR postdoc Sean Goldy (@seangoldy.bsky.social) spoke at the Centre for Psychedelic Research at Imperial College London and University of Edinburgh, presenting research on psychedelics’ acute subjective effects (e.g., awe), how session facilitators might shape these, and an upcoming trial
May 8, 2025 at 8:06 PM
Huge thanks to friends at @imperialcollegeldn.bsky.social
and @schoolofppls.bsky.social for hosting me and sparking some great discussions on psychedelics, well-being, and more.
(I promise I have more than one outfit)
and @schoolofppls.bsky.social for hosting me and sparking some great discussions on psychedelics, well-being, and more.
(I promise I have more than one outfit)
Reposted by KingFranklinIV
I was invited to join as Editorial Board Member of a new @elsevierconnect.bsky.social journal
Here's why I #declined an uncompensated role in #AcademicPublishing 🧵🧪🧠📈
Here's why I #declined an uncompensated role in #AcademicPublishing 🧵🧪🧠📈
May 8, 2025 at 1:09 PM
I was invited to join as Editorial Board Member of a new @elsevierconnect.bsky.social journal
Here's why I #declined an uncompensated role in #AcademicPublishing 🧵🧪🧠📈
Here's why I #declined an uncompensated role in #AcademicPublishing 🧵🧪🧠📈
Reposted by KingFranklinIV
Last but not least, I encourage #everyone to discuss these serious issues with @elsevierconnect.bsky.social and help other academics who are pressuring publishers to adopt better work agreements, more inclusive and respectful of all stakeholders work value and time commitments with their expertises.
May 8, 2025 at 1:09 PM
Last but not least, I encourage #everyone to discuss these serious issues with @elsevierconnect.bsky.social and help other academics who are pressuring publishers to adopt better work agreements, more inclusive and respectful of all stakeholders work value and time commitments with their expertises.
Reposted by KingFranklinIV
Finally out! Happy bicycle day.
Continuous EEG-fMRI before during and after administration of the psychedelic DMT reveals time-resolved alterations in human brain dynamics.
@parkersingleton.bsky.social
doi.org/10.1038/s420...
@parkersingleton.bsky.social
doi.org/10.1038/s420...
Network control energy reductions under DMT relate to serotonin receptors, signal diversity, and subjective experience - Communications Biology
Continuous EEG-fMRI before during and after administration of the psychedelic DMT reveals time-resolved alterations in human brain dynamics.
doi.org
April 19, 2025 at 12:10 PM
Finally out! Happy bicycle day.
Reposted by KingFranklinIV
Contextual effects in musculoskeletal pain: are we overlooking essential factors? www.frontiersin.org/journals/psy...
April 18, 2025 at 8:24 AM
Contextual effects in musculoskeletal pain: are we overlooking essential factors? www.frontiersin.org/journals/psy...
Reposted by KingFranklinIV
New review stating the inconvient truth regarding RCTs in #psychiatry:
"expectations and blinding integrity are rarely measured" 🧪
Then why #psychedelic critics repeatedly turned a blind eye to this, pretending psychedelic RCTs were less rigorous than usual ?!? 🤔
jamanetwork.com/journals/jam...
"expectations and blinding integrity are rarely measured" 🧪
Then why #psychedelic critics repeatedly turned a blind eye to this, pretending psychedelic RCTs were less rigorous than usual ?!? 🤔
jamanetwork.com/journals/jam...
Expectancy Effects, Blinding Integrity, and Placebo Response in Psychiatric Disorders
This narrative review discusses the impact of expectancy effects and functional unblinding on treatment responses in randomized clinical trials of treatments in psychiatry.
jamanetwork.com
March 31, 2025 at 9:20 AM
New review stating the inconvient truth regarding RCTs in #psychiatry:
"expectations and blinding integrity are rarely measured" 🧪
Then why #psychedelic critics repeatedly turned a blind eye to this, pretending psychedelic RCTs were less rigorous than usual ?!? 🤔
jamanetwork.com/journals/jam...
"expectations and blinding integrity are rarely measured" 🧪
Then why #psychedelic critics repeatedly turned a blind eye to this, pretending psychedelic RCTs were less rigorous than usual ?!? 🤔
jamanetwork.com/journals/jam...
Reposted by KingFranklinIV
How awe-inspiring are psychedelic experiences and why might emotions like awe play a role in psychedelics' benefits?
Excited to speak on this in our @affectscience.bsky.social symposium on awe today! #AffectScience2025
Excited to speak on this in our @affectscience.bsky.social symposium on awe today! #AffectScience2025
March 21, 2025 at 3:57 PM
How awe-inspiring are psychedelic experiences and why might emotions like awe play a role in psychedelics' benefits?
Excited to speak on this in our @affectscience.bsky.social symposium on awe today! #AffectScience2025
Excited to speak on this in our @affectscience.bsky.social symposium on awe today! #AffectScience2025
There's been a bit of press on the HALT act which would place fentanyl analogues into Sched 1, but I haven't seen any comment on the very significant changes proposed for Sched 1 research—for the better, it appears: www.congress.gov/bill/119th-c...
www.congress.gov
March 7, 2025 at 5:36 PM
There's been a bit of press on the HALT act which would place fentanyl analogues into Sched 1, but I haven't seen any comment on the very significant changes proposed for Sched 1 research—for the better, it appears: www.congress.gov/bill/119th-c...
Reposted by KingFranklinIV
How Much Should Americans Worry About Elon Musk’s Ketamine Use?
@shaylalove.bsky.social for The Atlantic.
www.theatlantic.com/health/archi...
@shaylalove.bsky.social for The Atlantic.
www.theatlantic.com/health/archi...
How Much Should Americans Worry About Elon Musk’s Ketamine Use?
Excessive use of the drug can make anyone feel like they rule the world.
www.theatlantic.com
March 5, 2025 at 7:57 PM
How Much Should Americans Worry About Elon Musk’s Ketamine Use?
@shaylalove.bsky.social for The Atlantic.
www.theatlantic.com/health/archi...
@shaylalove.bsky.social for The Atlantic.
www.theatlantic.com/health/archi...
Reposted by KingFranklinIV
A Rundown of Colorado’s Natural Medicine Program
A short, simple guide to CO's regulated psychedelics program's key rules and structure.
psychedelicalpha.com/news/a-rundo...
A short, simple guide to CO's regulated psychedelics program's key rules and structure.
psychedelicalpha.com/news/a-rundo...
A Rundown of Colorado’s Natural Medicine Program - Psychedelic Alpha
Now that the rules for Colorado’s regulated psychedelics program are set and license applications are open, Healing Advocacy Fund’s Colorado Director Tasia Poinsatte provides a brief…
psychedelicalpha.com
March 5, 2025 at 5:55 PM
A Rundown of Colorado’s Natural Medicine Program
A short, simple guide to CO's regulated psychedelics program's key rules and structure.
psychedelicalpha.com/news/a-rundo...
A short, simple guide to CO's regulated psychedelics program's key rules and structure.
psychedelicalpha.com/news/a-rundo...
Reposted by KingFranklinIV
Moving beyond "harm reduction" to "benefit enhancement" in psychedelic healthcare may be essential as more people seek guidance on therapeutic use. #psychedelicscience
Beyond 'do no harm': The ethics of maximizing benefit from psychedelics in healthcare - Journal of Medical Ethics blog
By Jason Luoma and Brian Pilecki. The use of psychedelics in the USA has rapidly increased over the last decade, not only for recreational purposes but also for therapeutic purposes. For example, rate...
blogs.bmj.com
March 5, 2025 at 11:36 PM
Moving beyond "harm reduction" to "benefit enhancement" in psychedelic healthcare may be essential as more people seek guidance on therapeutic use. #psychedelicscience
Psychedelics + grandiosity + tons of power, what could go wrong
March 5, 2025 at 7:36 PM
Psychedelics + grandiosity + tons of power, what could go wrong
Reposted by KingFranklinIV
Great work for psychedelic research to overcome RCT-based epistemic authoritarianism, led by @sdmuthu.bsky.social and @tehseennoorani.bsky.social 👏👏👏.
Thankful for the invite to to collaborate, together with @trpwolff.bsky.social, @mattbagg.bsky.social and others.
osf.io/preprints/ps... 🧪🧠💊
Thankful for the invite to to collaborate, together with @trpwolff.bsky.social, @mattbagg.bsky.social and others.
osf.io/preprints/ps... 🧪🧠💊
February 19, 2025 at 2:21 PM
Great work for psychedelic research to overcome RCT-based epistemic authoritarianism, led by @sdmuthu.bsky.social and @tehseennoorani.bsky.social 👏👏👏.
Thankful for the invite to to collaborate, together with @trpwolff.bsky.social, @mattbagg.bsky.social and others.
osf.io/preprints/ps... 🧪🧠💊
Thankful for the invite to to collaborate, together with @trpwolff.bsky.social, @mattbagg.bsky.social and others.
osf.io/preprints/ps... 🧪🧠💊
Happy to share that my group's new paper, "Psychedelic-assisted Therapy as a Promising Treatment for Irritable Bowel Syndrome", building on exciting cross-disciplinary work at Mass General Hospital, is now published in the Journal of Clinical Gastroenterology:
pubmed.ncbi.nlm.nih.gov/39998940/
pubmed.ncbi.nlm.nih.gov/39998940/
March 2, 2025 at 1:59 AM
Happy to share that my group's new paper, "Psychedelic-assisted Therapy as a Promising Treatment for Irritable Bowel Syndrome", building on exciting cross-disciplinary work at Mass General Hospital, is now published in the Journal of Clinical Gastroenterology:
pubmed.ncbi.nlm.nih.gov/39998940/
pubmed.ncbi.nlm.nih.gov/39998940/
Nice to see some fresh and audacious new ideas of things that have never been tried before, this must be the 'change' voters voted for
He added that the admin. is going to spend $100-200M on an ad campaign "saying how bad drugs are".
"One of the things we're going to do is we're going to do an advertising campaign, they're working on it right now, and that's saying how bad drugs are for you."
"One of the things we're going to do is we're going to do an advertising campaign, they're working on it right now, and that's saying how bad drugs are for you."
February 25, 2025 at 4:40 AM
Nice to see some fresh and audacious new ideas of things that have never been tried before, this must be the 'change' voters voted for
Reposted by KingFranklinIV
We’ve launched a new clinical trial exploring the efficacy of psilocybin therapy for anorexia nervosa in young adults (age 18 to 25)!
Learn more at tiny.ucsf.edu/HTkr9L or take our pre-screen survey to see if you’re a good fit tiny.ucsf.edu/gmvCA3.
Learn more at tiny.ucsf.edu/HTkr9L or take our pre-screen survey to see if you’re a good fit tiny.ucsf.edu/gmvCA3.
UCSF Anorexia Trial: Psilocybin for Anorexia in Young Adults
This Anorexia and Psilocybin study at UCSF is now recruiting people ages 18-25.
tiny.ucsf.edu
February 25, 2025 at 4:38 AM
We’ve launched a new clinical trial exploring the efficacy of psilocybin therapy for anorexia nervosa in young adults (age 18 to 25)!
Learn more at tiny.ucsf.edu/HTkr9L or take our pre-screen survey to see if you’re a good fit tiny.ucsf.edu/gmvCA3.
Learn more at tiny.ucsf.edu/HTkr9L or take our pre-screen survey to see if you’re a good fit tiny.ucsf.edu/gmvCA3.
Nice writeup. I think what is most interesting to observe in the tension referred to here is the selective use of science in these debates. You see a strange alliance among the critics on psychedelics, some of whom are aware (and vocally so) on the ways in which science and medicine often 1/
Mia Cara Cosco explores some of the major discussions at the event, including what she perceived to be palpable tensions surrounding the roles of science, spirituality, and commercialisation in the psychedelics field.
psychedelicalpha.com/news/a-cruci...
psychedelicalpha.com/news/a-cruci...
A Crucible of Academia, Psychedelics, and Religion: Psychedelic Intersections 2025 at The Harvard Divinity School - Psychedelic Alpha
Mia Cara Cosco attended Psychedelic Intersections at Harvard earlier this month and provides this Dispatch for Psychedelic Alpha. In her article, Cosco explores some of the major discussions at the…
psychedelicalpha.com
February 24, 2025 at 6:52 PM
Nice writeup. I think what is most interesting to observe in the tension referred to here is the selective use of science in these debates. You see a strange alliance among the critics on psychedelics, some of whom are aware (and vocally so) on the ways in which science and medicine often 1/
Cardiology study looking at people who use psychedelics a colleague is working on, please share, requires in person visit (Boston).
February 24, 2025 at 6:44 PM
Cardiology study looking at people who use psychedelics a colleague is working on, please share, requires in person visit (Boston).
1. Clinical research with psychedelics +/- acerbic commentary on same
2. Psilocybin-assisted [Acceptance and Commitment] therapy for irritable bowel syndrome
3. Just finished The Posthumous Memoirs of Brás Cubas, by Machado de Assis, and highly recommend. Started White Lotus S3 last night
2. Psilocybin-assisted [Acceptance and Commitment] therapy for irritable bowel syndrome
3. Just finished The Posthumous Memoirs of Brás Cubas, by Machado de Assis, and highly recommend. Started White Lotus S3 last night
Bluesky Psychedelics People: Let's (re-)intro ourselves to one another!
Quote this post and tell us:
1) What you do in the field
2) A project you're currently working on
3) A show/film/book you're enjoying
Quote this post and tell us:
1) What you do in the field
2) A project you're currently working on
3) A show/film/book you're enjoying
February 24, 2025 at 5:37 PM
1. Clinical research with psychedelics +/- acerbic commentary on same
2. Psilocybin-assisted [Acceptance and Commitment] therapy for irritable bowel syndrome
3. Just finished The Posthumous Memoirs of Brás Cubas, by Machado de Assis, and highly recommend. Started White Lotus S3 last night
2. Psilocybin-assisted [Acceptance and Commitment] therapy for irritable bowel syndrome
3. Just finished The Posthumous Memoirs of Brás Cubas, by Machado de Assis, and highly recommend. Started White Lotus S3 last night
Call for papers - General Hospital Psychiatry, special issue on psychedelics. GHP focuses on issues at the interface of psychiatry and general medical settings (eg, integrated care, med-psych, psychosomatics, CL psych, mental health services). Please share!
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
General Hospital Psychiatry | ScienceDirect.com by Elsevier - General Hospital Psychiatry | ScienceDirect.com by ElsevierScienceDirect
Read the latest articles of General Hospital Psychiatry at ScienceDirect.com, Elsevier’s leading platform of peer-reviewed scholarly literature
www.sciencedirect.com
February 24, 2025 at 3:26 AM
Call for papers - General Hospital Psychiatry, special issue on psychedelics. GHP focuses on issues at the interface of psychiatry and general medical settings (eg, integrated care, med-psych, psychosomatics, CL psych, mental health services). Please share!
www.sciencedirect.com/special-issu...
www.sciencedirect.com/special-issu...
My first post will be the paper I co-authored with many fine people, and that I hope will help anyone crazy enough to think they want to do psychedelic research: "Practical considerations in the establishment of psychedelic research programs". It's open access.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Practical considerations in the establishment of psychedelic research programs - Psychopharmacology
Rationale There is increasing interest in establishing psychedelic research programs at academic medical centers. However, psychedelics are intensely psychoactive, carry considerable sociopolitical ba...
link.springer.com
February 24, 2025 at 1:02 AM
My first post will be the paper I co-authored with many fine people, and that I hope will help anyone crazy enough to think they want to do psychedelic research: "Practical considerations in the establishment of psychedelic research programs". It's open access.
link.springer.com/article/10.1...
link.springer.com/article/10.1...