Sean Goldy
@seangoldy.bsky.social
Postdoc at Johns Hopkins Center for Psychedelic and Consciousness Research @jhpsychedelics.bsky.social| Psychologist studying the subjective effects of psychedelics
Love this new review on psychedelics & emotions from colleagues!
One theme—how we measure positive emotions— resonates with our paper on why distinct positive emotions need more focus in psychedelic science, given their potential role in therapeutic benefits: www.tandfonline.com/doi/10.1080/...
One theme—how we measure positive emotions— resonates with our paper on why distinct positive emotions need more focus in psychedelic science, given their potential role in therapeutic benefits: www.tandfonline.com/doi/10.1080/...
August 19, 2025 at 9:10 AM
Love this new review on psychedelics & emotions from colleagues!
One theme—how we measure positive emotions— resonates with our paper on why distinct positive emotions need more focus in psychedelic science, given their potential role in therapeutic benefits: www.tandfonline.com/doi/10.1080/...
One theme—how we measure positive emotions— resonates with our paper on why distinct positive emotions need more focus in psychedelic science, given their potential role in therapeutic benefits: www.tandfonline.com/doi/10.1080/...
📢Had a blast presenting our work on psychedelic facilitator's effects at #PS2025, catching up w/ friends, & seeing what's next for the field, like:
New trials w/ novel psychedelics?
New start-ups to help scale treatments?
Regulatory updates?
A new conference outfit for me?
So many possibilities
New trials w/ novel psychedelics?
New start-ups to help scale treatments?
Regulatory updates?
A new conference outfit for me?
So many possibilities
June 30, 2025 at 5:34 PM
📢Had a blast presenting our work on psychedelic facilitator's effects at #PS2025, catching up w/ friends, & seeing what's next for the field, like:
New trials w/ novel psychedelics?
New start-ups to help scale treatments?
Regulatory updates?
A new conference outfit for me?
So many possibilities
New trials w/ novel psychedelics?
New start-ups to help scale treatments?
Regulatory updates?
A new conference outfit for me?
So many possibilities
How much do psychedelics' subjective effects--which can predict treatment outcomes--shift depending on who guides/facilitates your experience?
Looking forward to presenting on years of trial data examining this question at #PsychedelicScience2025!
Check it out at 10am on 6/19 & hmu if in town!
Looking forward to presenting on years of trial data examining this question at #PsychedelicScience2025!
Check it out at 10am on 6/19 & hmu if in town!
June 10, 2025 at 7:16 PM
How much do psychedelics' subjective effects--which can predict treatment outcomes--shift depending on who guides/facilitates your experience?
Looking forward to presenting on years of trial data examining this question at #PsychedelicScience2025!
Check it out at 10am on 6/19 & hmu if in town!
Looking forward to presenting on years of trial data examining this question at #PsychedelicScience2025!
Check it out at 10am on 6/19 & hmu if in town!
Huge thanks to friends at @imperialcollegeldn.bsky.social
and @schoolofppls.bsky.social for hosting me and sparking some great discussions on psychedelics, well-being, and more.
(I promise I have more than one outfit)
and @schoolofppls.bsky.social for hosting me and sparking some great discussions on psychedelics, well-being, and more.
(I promise I have more than one outfit)
CPCR postdoc Sean Goldy (@seangoldy.bsky.social) spoke at the Centre for Psychedelic Research at Imperial College London and University of Edinburgh, presenting research on psychedelics’ acute subjective effects (e.g., awe), how session facilitators might shape these, and an upcoming trial
May 8, 2025 at 8:06 PM
Huge thanks to friends at @imperialcollegeldn.bsky.social
and @schoolofppls.bsky.social for hosting me and sparking some great discussions on psychedelics, well-being, and more.
(I promise I have more than one outfit)
and @schoolofppls.bsky.social for hosting me and sparking some great discussions on psychedelics, well-being, and more.
(I promise I have more than one outfit)
Reposted by Sean Goldy
Our new paper - the first peer-reviewed brain and phenomenological examination of 5-MeO-DMT is out in Neuro of Consciousness.
TLDR: We tested whether ‘the mount Everest’ of psychedelics could induce a complete state of consciousness deconstruction while preserving awareness. 1/n
#neuroskyence
TLDR: We tested whether ‘the mount Everest’ of psychedelics could induce a complete state of consciousness deconstruction while preserving awareness. 1/n
#neuroskyence
April 23, 2025 at 2:06 PM
Our new paper - the first peer-reviewed brain and phenomenological examination of 5-MeO-DMT is out in Neuro of Consciousness.
TLDR: We tested whether ‘the mount Everest’ of psychedelics could induce a complete state of consciousness deconstruction while preserving awareness. 1/n
#neuroskyence
TLDR: We tested whether ‘the mount Everest’ of psychedelics could induce a complete state of consciousness deconstruction while preserving awareness. 1/n
#neuroskyence
Great fun presenting my program of research covering the science of self-transcendence at @ucl.ac.uk and @uclsap.bsky.social’s @unityproject.bsky.social project.
CPCR Postdoc Sean Goldy (@seangoldy.bsky.social) presenting on the science of self-transcendence to University College London
April 17, 2025 at 12:04 PM
Great fun presenting my program of research covering the science of self-transcendence at @ucl.ac.uk and @uclsap.bsky.social’s @unityproject.bsky.social project.
‼️Excited to speak at this year's @breakingconvention.bsky.social ! I'll cover our work on how much people's subjective effects differ by who guides them, spanning years of clinical trials and hundreds of participants at @JHPsychedelics. First time attending Breaking Convention, too! 👋
April 14, 2025 at 11:07 AM
‼️Excited to speak at this year's @breakingconvention.bsky.social ! I'll cover our work on how much people's subjective effects differ by who guides them, spanning years of clinical trials and hundreds of participants at @JHPsychedelics. First time attending Breaking Convention, too! 👋
Reposted by Sean Goldy
So the first "psilocybin healing centre" has finally opened in Colorado. Price is USD$2,000 for an 8-hour facilitated dose session plus a couple of pre and post consultations.
Guided Journey Work Package | The Center Origin
Are you seeking profound healing, inner peace, and a deeper connection with yourself & others? Our Journey Work Program is carefully designed to guide you through a transformative experience that tran...
www.thecenterorigin.com
April 3, 2025 at 4:48 AM
So the first "psilocybin healing centre" has finally opened in Colorado. Price is USD$2,000 for an 8-hour facilitated dose session plus a couple of pre and post consultations.
How awe-inspiring are psychedelic experiences and why might emotions like awe play a role in psychedelics' benefits?
Excited to speak on this in our @affectscience.bsky.social symposium on awe today! #AffectScience2025
Excited to speak on this in our @affectscience.bsky.social symposium on awe today! #AffectScience2025
March 21, 2025 at 3:57 PM
How awe-inspiring are psychedelic experiences and why might emotions like awe play a role in psychedelics' benefits?
Excited to speak on this in our @affectscience.bsky.social symposium on awe today! #AffectScience2025
Excited to speak on this in our @affectscience.bsky.social symposium on awe today! #AffectScience2025
‼️Compelling new RCT work on psilocybin for AUD led by the outstanding @nathalierieser.bsky.social! Raises important questions about what might and might not work in psychedelic-assisted treatment for AUD. A monumental effort that grows our knowledge of psychedelics👏
Hi everyone, if you are interested in #psychedelic-assisted therapy, we just published a new study: www.sciencedirect.com/science/arti.... Congratulations to Dr. Nathalie Rieser, who has done a terrific job spearheading this project.
Psilocybin-assisted therapy for relapse prevention in alcohol use disorder: a phase 2 randomized clinical trial
Despite the promising therapeutic effects of psilocybin, its efficacy in preventing relapse after withdrawal treatment for alcohol use disorder (AUD) …
www.sciencedirect.com
March 17, 2025 at 2:59 PM
‼️Compelling new RCT work on psilocybin for AUD led by the outstanding @nathalierieser.bsky.social! Raises important questions about what might and might not work in psychedelic-assisted treatment for AUD. A monumental effort that grows our knowledge of psychedelics👏
❓ How much do psychedelic guides influence people's hashtag psychedelic experiences in clinical trials?
📢 Next Friday at ISRP (www.isrpsych.org), I'll present some exciting work on the impacts of guides/therapists on people's psychedelic subjective effects.
📢 Next Friday at ISRP (www.isrpsych.org), I'll present some exciting work on the impacts of guides/therapists on people's psychedelic subjective effects.
February 28, 2025 at 5:51 PM
❓ How much do psychedelic guides influence people's hashtag psychedelic experiences in clinical trials?
📢 Next Friday at ISRP (www.isrpsych.org), I'll present some exciting work on the impacts of guides/therapists on people's psychedelic subjective effects.
📢 Next Friday at ISRP (www.isrpsych.org), I'll present some exciting work on the impacts of guides/therapists on people's psychedelic subjective effects.
Here at Hopkins, we now have a clinic for people experiencing difficulties after a psychedelic experience--the first of it's kind. Please share widely to help get the word out for those who might need help!
Proud to be part of such a world-class team extending research & care around psychedelics.
Proud to be part of such a world-class team extending research & care around psychedelics.
Excited to announce a clinic for individuals experiencing difficulties following a psychedelic experience. I believe this is the first clinic of its kind in the US and is right here at
@HopkinsMedicine
, where we aim to learn about & address the benefits & risks of psychedelics
🧵
@HopkinsMedicine
, where we aim to learn about & address the benefits & risks of psychedelics
🧵
February 12, 2025 at 3:16 PM
Here at Hopkins, we now have a clinic for people experiencing difficulties after a psychedelic experience--the first of it's kind. Please share widely to help get the word out for those who might need help!
Proud to be part of such a world-class team extending research & care around psychedelics.
Proud to be part of such a world-class team extending research & care around psychedelics.
Come join us at what I think is one of the coolest places to work, study, and thrive, all while expanding our understanding of psychedelics 🪐
Join the world’s premier psychedelic research center!
My lab at
@JHPsychedelics
is hiring 3 Research Program Coordinators. We're looking for talented, hard-working, rigorous emerging scientists to contribute to scientific studies, including psychedelic admin trials.
Links:
My lab at
@JHPsychedelics
is hiring 3 Research Program Coordinators. We're looking for talented, hard-working, rigorous emerging scientists to contribute to scientific studies, including psychedelic admin trials.
Links:
February 5, 2025 at 4:09 PM
Come join us at what I think is one of the coolest places to work, study, and thrive, all while expanding our understanding of psychedelics 🪐
Reposted by Sean Goldy
A new review of prep materials led by CPCR Faculty David Yaden (@existwell.bsky.social) shows psilocybin trial prep materials strongly emphasize safety yet can also shape participant expectations—highlighting a delicate balance between ensuring well-being and avoiding unintended bias.
January 28, 2025 at 3:42 PM
A new review of prep materials led by CPCR Faculty David Yaden (@existwell.bsky.social) shows psilocybin trial prep materials strongly emphasize safety yet can also shape participant expectations—highlighting a delicate balance between ensuring well-being and avoiding unintended bias.
Why should we consider distinct positive emotions--like awe, compassion, or gratitude--in psychedelic science? 🧵
www.tandfonline.com/eprint/MMUW7...
www.tandfonline.com/eprint/MMUW7...
Considering distinct positive emotions in psychedelic science
In this review, we discuss psychedelics’ acute subjective and persisting therapeutic effects, outline the science of positive emotions, and highlight the value in considering distinct positive emot...
www.tandfonline.com
December 18, 2024 at 4:56 PM
Why should we consider distinct positive emotions--like awe, compassion, or gratitude--in psychedelic science? 🧵
www.tandfonline.com/eprint/MMUW7...
www.tandfonline.com/eprint/MMUW7...
Reposted by Sean Goldy
New article on psychedelic risks and benefits in naturalistic use led by CPCR postdoc Sean Goldy (@seangoldy.bsky.social), featuring David Yaden (@existwell.bsky.social) and many others. Check out the thread below !
Link to original publication: journals.sagepub.com/doi/full/10....
Link to original publication: journals.sagepub.com/doi/full/10....
1/ 🚨 New paper alert! Across 2 studies (N = 1,257) using a panel service to get more representative samples, we compared psychedelic experiences to cannabis ones in terms of both immediate and long-term risks and benefits. Here's what we discovered! 👇
journals.sagepub.com/eprint/QPYJ7...
journals.sagepub.com/eprint/QPYJ7...
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
journals.sagepub.com
December 6, 2024 at 2:13 PM
New article on psychedelic risks and benefits in naturalistic use led by CPCR postdoc Sean Goldy (@seangoldy.bsky.social), featuring David Yaden (@existwell.bsky.social) and many others. Check out the thread below !
Link to original publication: journals.sagepub.com/doi/full/10....
Link to original publication: journals.sagepub.com/doi/full/10....
1/ 🚨 New paper alert! Across 2 studies (N = 1,257) using a panel service to get more representative samples, we compared psychedelic experiences to cannabis ones in terms of both immediate and long-term risks and benefits. Here's what we discovered! 👇
journals.sagepub.com/eprint/QPYJ7...
journals.sagepub.com/eprint/QPYJ7...
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
journals.sagepub.com
December 3, 2024 at 5:51 PM
1/ 🚨 New paper alert! Across 2 studies (N = 1,257) using a panel service to get more representative samples, we compared psychedelic experiences to cannabis ones in terms of both immediate and long-term risks and benefits. Here's what we discovered! 👇
journals.sagepub.com/eprint/QPYJ7...
journals.sagepub.com/eprint/QPYJ7...
🔬Our new paper outlines the limits of our understanding of psychedelics' subjective effects & how we can improve our science moving forward, going beyond just mystical experience. Proud to be a part of this with @existwell.bsky.social, Brandon Weiss, & Roland Griffiths.
It’s high time the field of psychedelic research move beyond the mystical experience construct (MEQ). While many critiques of the measure rest on misconceptions, persistent misunderstandings & psychometric limitations lead us to recommend transcending it.
- Nature R Psy: nature.com/articles/s44...
- Nature R Psy: nature.com/articles/s44...
Clinically relevant acute subjective effects of psychedelics beyond mystical experience - Nature Reviews Psychology
The therapeutic benefits of psychedelics might be ascribed to their subjective effects, but methodological barriers limit interpretation of this association. In this Review, Yaden et al. balance the l...
nature.com
November 27, 2024 at 6:16 PM
🔬Our new paper outlines the limits of our understanding of psychedelics' subjective effects & how we can improve our science moving forward, going beyond just mystical experience. Proud to be a part of this with @existwell.bsky.social, Brandon Weiss, & Roland Griffiths.
Reposted by Sean Goldy
Written with huge assistance from CPCR faculty
Brandon Weiss & CPCR postdoc
@seangoldy.bsky.social. This project sparked many fruitful discussions on the topic. Roland Griffiths, who often voiced his problems with the 'mystical' label, worked on the paper before he died
@jhpsychedelics.bsky.social
Brandon Weiss & CPCR postdoc
@seangoldy.bsky.social. This project sparked many fruitful discussions on the topic. Roland Griffiths, who often voiced his problems with the 'mystical' label, worked on the paper before he died
@jhpsychedelics.bsky.social
November 27, 2024 at 4:56 PM
Written with huge assistance from CPCR faculty
Brandon Weiss & CPCR postdoc
@seangoldy.bsky.social. This project sparked many fruitful discussions on the topic. Roland Griffiths, who often voiced his problems with the 'mystical' label, worked on the paper before he died
@jhpsychedelics.bsky.social
Brandon Weiss & CPCR postdoc
@seangoldy.bsky.social. This project sparked many fruitful discussions on the topic. Roland Griffiths, who often voiced his problems with the 'mystical' label, worked on the paper before he died
@jhpsychedelics.bsky.social
Case study of "non-hallucinogenic psychedelic" Tabernanthalog suggests it might evoke feelings of “supernatural patience”.
N = 1, but it points to the need for more research on the psychological impacts of these compounds.
awjuliani.medium.com/a-phenomenol...
N = 1, but it points to the need for more research on the psychological impacts of these compounds.
awjuliani.medium.com/a-phenomenol...
December 30, 2023 at 9:24 PM
Case study of "non-hallucinogenic psychedelic" Tabernanthalog suggests it might evoke feelings of “supernatural patience”.
N = 1, but it points to the need for more research on the psychological impacts of these compounds.
awjuliani.medium.com/a-phenomenol...
N = 1, but it points to the need for more research on the psychological impacts of these compounds.
awjuliani.medium.com/a-phenomenol...
Is 5-MeO-DMT an aytpical psychedelic? Some work suggests so:
-Greater affinity for 5-HT1A receptors
-More likely to produce "reactivation" experiences
-Unique trip effects, like "white outs"
link.springer.com/article/10.1...
-Greater affinity for 5-HT1A receptors
-More likely to produce "reactivation" experiences
-Unique trip effects, like "white outs"
link.springer.com/article/10.1...
December 12, 2023 at 8:58 PM
Is 5-MeO-DMT an aytpical psychedelic? Some work suggests so:
-Greater affinity for 5-HT1A receptors
-More likely to produce "reactivation" experiences
-Unique trip effects, like "white outs"
link.springer.com/article/10.1...
-Greater affinity for 5-HT1A receptors
-More likely to produce "reactivation" experiences
-Unique trip effects, like "white outs"
link.springer.com/article/10.1...
What are the ethical considerations of "nonsubjective" (tripless) psychedelics? What might we lose without the trip?
A lot is at stake if we remove the choice to potentially have deeply meaningful experiences via psychedelics: www.cambridge.org/core/journal...
A lot is at stake if we remove the choice to potentially have deeply meaningful experiences via psychedelics: www.cambridge.org/core/journal...
December 4, 2023 at 5:37 PM
What are the ethical considerations of "nonsubjective" (tripless) psychedelics? What might we lose without the trip?
A lot is at stake if we remove the choice to potentially have deeply meaningful experiences via psychedelics: www.cambridge.org/core/journal...
A lot is at stake if we remove the choice to potentially have deeply meaningful experiences via psychedelics: www.cambridge.org/core/journal...
New work from Ceyda Sayali and co here at Hopkins on Ritalin and its varying, *not* one-size-fits-all impacts on creativity
www.psypost.org/2023/11/rita...
www.psypost.org/2023/11/rita...
November 30, 2023 at 2:39 PM
New work from Ceyda Sayali and co here at Hopkins on Ritalin and its varying, *not* one-size-fits-all impacts on creativity
www.psypost.org/2023/11/rita...
www.psypost.org/2023/11/rita...
What are now typically known as psychedelics have been/are called a lot of different things.
We've got hallucinogens, psychotomimetics, entheogens, empatho/entactogens (for MDMA)...what's next/what feels the most relevant?
We've got hallucinogens, psychotomimetics, entheogens, empatho/entactogens (for MDMA)...what's next/what feels the most relevant?
November 13, 2023 at 7:48 PM
What are now typically known as psychedelics have been/are called a lot of different things.
We've got hallucinogens, psychotomimetics, entheogens, empatho/entactogens (for MDMA)...what's next/what feels the most relevant?
We've got hallucinogens, psychotomimetics, entheogens, empatho/entactogens (for MDMA)...what's next/what feels the most relevant?
Imperial's Centre for Psychedelic Research finds that continuous DMT infusion was well-tolerated (low anxiety), with sustained peak effects over time (~42min‼️).
journals.sagepub.com/doi/epub/10....
journals.sagepub.com/doi/epub/10....
October 30, 2023 at 8:19 PM
Imperial's Centre for Psychedelic Research finds that continuous DMT infusion was well-tolerated (low anxiety), with sustained peak effects over time (~42min‼️).
journals.sagepub.com/doi/epub/10....
journals.sagepub.com/doi/epub/10....