Lol I just logged on for the first time today in weeks and saw this

Josh, I heard a couple years ago that they had purchased an island in St. Vincent and the Grenadines, which has some kind of medical psychedelic law… supposedly they were planning to operate some sort of research-collecting retreat… have you heard anything about this?

Even so, it’s seems like it’s not uniform so I think there’s something else there, and it might yield useful insights to know why if this could ever be determined.

I’ve wondered that, but that’s not what I’ve seen in practice… some people (eg those who aren’t that depressed or anxious but go on a SSRI) have no blunting, and some who are very depressed and desperate for relief get it. But it does seem to be noticed more in milder conditions.

Last but not least, I encourage #everyone to discuss these serious issues with @elsevierconnect.bsky.social and help other academics who are pressuring publishers to adopt better work agreements, more inclusive and respectful of all stakeholders work value and time commitments with their expertises.

The emotional blunting by SSRIs is interesting, since at least in my clinical experience affects only a minority of patients, so the question is… why? I wonder if there might be correlation between psychological types who develop blunting and certain types of responses to psilocybin.

I think an archaeologist would be a lot more qualified to make this observation, personally, but it’s worth noting that across cultures, the more elaborate the object, the less likely it is that it’s used for anything mundane. The “handles” on the mushrooms stones are not good handles.

Also, this paper, which well worth the read: www.nature.com/articles/s41...

I can’t find it now, but there’s a story from a few years ago (I think on Vice) by someone who used to be a raver in the 90s, about how her most transformative MDMA experiences were the conversations she had with strangers waiting in line to use the bathroom. Perhaps another angle of this question.

So I don’t think these results are surprising, and I don’t think they are applicable to most patients who might be looking for therapeutic psychedelic experiences. But it certainly should give everyone pause as to what the “medicine” actually is.

It says it included people who used psychedelics with therapeutic intent. Anyone who’s going to a rave and has therapeutic intent has at least some amount of psychological, and psychedelic, literacy already, and probably a social container( ie, friends, and friends who use psychedelics). So…

@trpwolff.bsky.social @eeschenberg.bsky.social

The latter are truly evil.

cc: @josh-hardman.bsky.social