Joseph Flynn, MD
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jostflynnmd.bsky.social
Joseph Flynn, MD
@jostflynnmd.bsky.social
Professor of Pediatrics, University of Washington and Nephrologist at Seattle Children's/Editor-in-Chief @ped-neph.bsky.social/ PGY-39 / 🏳️‍🌈
This is a great commentary - really enjoyed it @aspneph.bsky.social #nephsky #pedsky @ipna.bsky.social
New from Dr Gbadegesin in AJKD

KDOQI US Commentary on the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children

https://pubmed.ncbi.nlm.nih.gov/41577383/
January 24, 2026 at 10:03 PM
Reposted by Joseph Flynn, MD
steroid reduction in GN

www.kireports.org/article/S246...

excellent review by ottawa GN group in @kireports.bsky.social @michael-toal.bsky.social and team
January 24, 2026 at 4:33 PM
Reposted by Joseph Flynn, MD
“These actions will make Americans less safe and more vulnerable to gun violence,” Georgia Senator Raphael Warnock, Maryland Senator Angela Alsobrooks, and six members of Congress wrote in a letter to Attorney General Pam Bondi.
Bulletin: Lawmakers Blast Federal Funding Cuts to Gun Violence Prevention
A Trace analysis found that the Trump administration has terminated grants worth more than $200 million for gun violence prevention programs and research.
www.thetrace.org
January 23, 2026 at 3:27 PM
Reposted by Joseph Flynn, MD
It's @pasmeeting.bsky.social Abstract Notification day!! Good luck to everyone, especially @aspneph.bsky.social @babykidney.bsky.social researchers. Looking forward to hearing about all the posters and platform presentations!
January 15, 2026 at 3:46 PM
This is spot-on!
I think it’s time to trot out one of my favorite TV show quotes of all time.
January 19, 2026 at 1:55 AM
Reposted by Joseph Flynn, MD
More great news from Dr. Katherine Tuttle, who is quoted in the article: "Mechanistic effects of semaglutide reduce albuminuria, preserve glomerular filtration." @uwmedicine.bsky.social @uwnephrology.bsky.social #nephsky #kidney #glomerular #CKD #semaglutide #diabetes

www.healio.com/news/nephrol...
Mechanistic effects of semaglutide reduce albuminuria, preserve glomerular filtration
HOUSTON — Semaglutide demonstrated efficacy in reducing albuminuria and preserving glomerular filtration for patients with chronic kidney disease and type 2 diabetes, according to study data presented...
www.healio.com
December 4, 2025 at 6:33 PM
Reposted by Joseph Flynn, MD
Dr. Mike Granda presents "Go or No Go: Gray Zones and Recent Evidence in Obstructive AKI."
#kidney #AKI #nephsky #renal @uwmedicine.bsky.social
Watch: youtu.be/oTAEOg9xJF0
Michael Granda, MD - Go or No Go: Gray Zones and Recent Evidence in Obstructive AKI
YouTube video by University of Washington Division of Nephrology
youtu.be
January 12, 2026 at 8:50 PM
The feasibility of noninvasive blood pressure monitoring in infants with a birth weight under 500 grams
www.nature.com/articles/s41...
January 12, 2026 at 4:08 AM
Reposted by Joseph Flynn, MD
>2,100 research projects funded by the NIH were terminated in 2025...In this comment, patients, care partners, and scientists share our perspective about what's at stake...and why advocacy is essential to our path forward @natureportfolio.nature.com @apha.org @aclu.org www.nature.com/articles/s41...
October 15, 2025 at 5:22 PM
Reposted by Joseph Flynn, MD
Kidney function monitoring in pediatric sickle cell disease: evidence from the NEPHRODREPA study
#nephsky
Kidney function monitoring in pediatric sickle cell disease: evidence from the NEPHRODREPA study - Pediatric Nephrology
Background Sickle cell disease (SCD) induces early kidney abnormalities, beginning in childhood with glomerular hyperfiltration and progressing toward chronic kidney disease. Estimating glomerular…
buff.ly
January 10, 2026 at 9:00 PM
Reposted by Joseph Flynn, MD
Case report: When the kidneys speak for the brain: a nephrological presentation of a rare neurological disorder
#nephsky
When the kidneys speak for the brain: a nephrological presentation of a rare neurological disorder - Pediatric Nephrology
Lesch–Nyhan syndrome (LNS) is a rare X-linked recessive disorder caused by complete deficiency of hypoxanthine-guanine phosphoribosyltransferase (HPRT). While the disease is classically characterized…
buff.ly
January 11, 2026 at 10:00 PM
Reposted by Joseph Flynn, MD
DAN-RSV phase 4 trial: Respiratory syncytial virus causes some 470,000 hospitalizations and 33,000 deaths in industrialized countries annually. Research findings on the bivalent RSV prefusion F protein–based vaccine are summarized in a new Quick Take video. nej.md/4qKqmWE

#MedSky #CardioSky
January 11, 2026 at 8:01 PM
Comparison of two validated oscillometric devices in a home-like setup reveals pronounced blood pressure differences and reduced precision
www.nature.com/articles/s41...
January 11, 2026 at 8:12 PM
Reposted by Joseph Flynn, MD
The phase 3 APPEAR-C3G study showed iptacopan significantly reduced proteinuria at 6 months in people with C3 glomerulopathy. #nephrology #nephsky #C3G
www.docwirenews.com/post/iptacop...
Iptacopan Is Safe and Effective for Patients With C3G | Docwire News
Iptacopan showed strong proteinuria reduction in C3 glomerulopathy (C3G) at 6 months when added to supportive care including RAAS inhibition and immunosuppression.
www.docwirenews.com
January 6, 2026 at 6:23 PM
Reposted by Joseph Flynn, MD
Tacrolimus is an essential immunosuppressive therapy to prevent acute rejection post-kidney transplantation. Read this Original Article on tacrolimus trough levels on acute rejection in pediatric kidney transplant recipients. Open Access
link.springer.com/article/10.1...
January 5, 2026 at 9:13 PM
Reposted by Joseph Flynn, MD
Neonatal AKI is common in infants born extremely preterm (EPT, <28 wks gestation), is assoc w/increased mortality & likely to be assoc w/kidney dysfunction later in life. Read this Original Article on AKI in EPT infants: findings from an Australian study.
link.springer.com/article/10.1...
January 6, 2026 at 6:34 PM
Reposted by Joseph Flynn, MD
Albuminuria is an established early marker of kidney damage & a strong predictor of cardiovascular risk. Read this Original Article on the association between serum 25-hydroxyvitamin D levels & urinary albumin-to-creatinine ratio among Korean adolescents.
link.springer.com/article/10.1...
January 6, 2026 at 7:04 PM
Reposted by Joseph Flynn, MD
Wow - excellent discussion of the totally underwhelming BICAR-ICU2 trial

podcasts.apple.com/ca/podcast/f...

@nephcrit.bsky.social fighting a line fight against the unimpressed nephrons with guest @weddellite.bsky.social

#NephSky #EMIMCC
FF 88 BICARICU-2, Bicarbonate in the ICU. Helpful or just a number fixer?
Podcast Episode · Freely Filtered, a NephJC Podcast · 2025-12-27 · 1h 25m
podcasts.apple.com
January 3, 2026 at 3:07 AM
Reposted by Joseph Flynn, MD
Children w/refractory nephrotic syndrome (NS) often experience frequent relapses despite combination immunosuppressive therapy. Read this Original Article on scheduled rituximab in children w/refractory NS after multi-target therapy failure. Open Access
link.springer.com/article/10.1...
January 2, 2026 at 7:55 PM