aspneph.bsky.social
@aspneph.bsky.social
A Pooled Analysis of Sex Differences in Lupus Nephritis
A Pooled Analysis of Sex Differences in Lupus Nephritis
Lupus nephritis (LN) has been reported to be more severe and have worse outcomes in males than females. In order to determine if sex differences exist in disease severity at diagnosis or relapse,…
buff.ly
November 9, 2025 at 11:30 PM
Thirst, sodium, and the hospitalized child: rethinking hypernatremia
(Editorial Commentary )
Thirst, sodium, and the hospitalized child: rethinking hypernatremia - Pediatric Nephrology
Pediatric Nephrology -
buff.ly
November 9, 2025 at 7:22 PM
Iptacopan in patients with IgA nephropathy from East Asia
Iptacopan in patients with IgA nephropathy from East Asia
IgA nephropathy (IgAN) has a high risk of progression to kidney failure in East Asia. At the Month 9 interim analysis (IA) of APPLAUSE-IgAN, iptacopan, a complement factor B inhibitor, demonstrated a…
buff.ly
November 9, 2025 at 3:30 PM
Creatinine’s hidden compartments: why cystatin C “Gets there first”
Creatinine’s hidden compartments: why cystatin C “Gets there first” - Pediatric Nephrology
Pediatric Nephrology -
buff.ly
November 8, 2025 at 7:20 PM
Commentary on “Risk factors for perinatal and neonatal mortality in cases with congenital anomalies of the kidney and urinary tract: a nested cohort study” (letter to editors)
Commentary on “Risk factors for perinatal and neonatal mortality in cases with congenital anomalies of the kidney and urinary tract: a nested cohort study” - Pediatric Nephrology
Pediatric Nephrology -
buff.ly
November 8, 2025 at 2:00 PM
Biomarker prediction of delayed graft function and prognosis post-kidney transplantation
Biomarker prediction of delayed graft function and prognosis post-kidney transplantation
Aminoacylase-1 (ACY1) and additional biomarkers were evaluated for prediction of delayed graft function (DGF) and prognosis following kidney transplantation.
buff.ly
November 7, 2025 at 9:45 PM
Delphi consensus on surrogate endpoints in C3G and primary IC-MPGN
Delphi consensus on surrogate endpoints in C3G and primary IC-MPGN
C3 glomerulopathy (C3G) and primary immune complex-mediated membranoproliferative glomerulonephritis (IC-MPGN) are rare kidney diseases driven by complement dysregulation. Proteinuria is a commonly…
buff.ly
November 7, 2025 at 6:32 PM
Welcome new ASPN councilors!
Grateful to John David Spencer, Zubin Modi, and Keia Sanderson for their commitment to advancing the care of children with kidney disease and to supporting our vibrant pediatric nephrology community. We look forward to their leadership and contributions in the years!
November 7, 2025 at 4:01 PM
Current and Emerging Therapies for C3 Glomerulopathy and Primary (Idiopathic) Immune Complex Membranoproliferative Glomerulonephritis (review)
buff.ly/Q3Xy09A
Current and Emerging Therapies for C3 Glomerulopathy and Primary (Idiopathic) Immune Complex Membranoproliferative Glomerulonephritis
C3 glomerulopathy (C3G) and primary (idiopathic) immune complex membranoproliferative glomerulonephritis (IC-MPGN) are rare kidney diseases characterized by dysregulation of the complement system and…
www.kireports.org
November 7, 2025 at 3:29 PM
Liver cyst infection outcomes in patients with autosomal dominant polycystic kidney disease.
buff.ly/ErJ7Iaa
Liver cyst infection outcomes in patients with autosomal dominant polycystic kidney disease.
Liver cyst infection is a rare and severe complication of the liver cysts associated with autosomal dominant polycystic kidney disease (ADPKD), and evidence-based data for optimal management is…
www.kireports.org
November 7, 2025 at 12:24 PM
Automatically Measuring Kidney, Liver, and Cyst Volumes in Autosomal Dominant Polycystic Kidney Disease
buff.ly
November 6, 2025 at 5:52 PM
Review: Visceral #Obesity and Metabolic Dysfunction in IgA Nephropathy: Nutritional and Metabolic Perspectives on Disease Progression
#openaccess
#nephsky
buff.ly
November 3, 2025 at 5:04 PM
Prevalence of high blood pressure and #hypertension among children and adolescents in Europe: a systematic review and meta-analysis
#openaccess
buff.ly
November 3, 2025 at 12:01 PM
Cardiac Biomarkers in Chronic Kidney Disease: Signal or Noise?
buff.ly
November 2, 2025 at 10:00 PM
Review: Complement Profiling in Glomerular Disease: Insights from Laser Microdissection and Mass Spectrometry
#nephsky
buff.ly
November 2, 2025 at 4:00 PM
Sodium glucose cotransporter 2 inhibition does not improve active lupus nephritis in MRLlpr/lpr mice
#nephsky
Sodium glucose cotransporter 2 inhibition does not improve active lupus nephritis in MRLlpr/lpr mice
Sodium glucose cotransporter 2 inhibitors (SGT2i) have delayed the progression of chronic kidney disease with or without diabetes. However, its effect in active glomerulonephritis such as lupus…
buff.ly
November 1, 2025 at 9:00 PM
Review: Drug repurposing in PIK3CA-related overgrowth spectrum: breakthroughs from overgrowth syndromes to kidney disease
#openaccess
#nephsky
Drug repurposing in PIK3CA-related overgrowth spectrum: breakthroughs from overgrowth syndromes to kidney disease
PI3Kα is a ubiquitous lipid kinase that transduces extracellular growth, proliferation and metabolism signals. Genes involved in the PI3Kα signaling pathway are frequently mutated in cancer. Apart…
www.kidney-international.org
November 1, 2025 at 6:01 PM
Single-cell spatial transcriptomics reveal intraglomerular cell activation and ligand-receptor relationships in chronic, active antibody mediated rejection
#nephsky
Single-cell spatial transcriptomics reveal intraglomerular cell activation and ligand-receptor relationships in chronic, active antibody mediated rejection
Chronic active antibody-mediated rejection (CAMR) is a leading cause of late kidney allograft dysfunction, characterized by transplant glomerulopathy involving glomerular endothelial cells (GEC),…
buff.ly
November 1, 2025 at 3:00 PM
Infliximab for Grade III/IV ICI Nephritis Clinical and Translational Evidence
#openaccess
#nephsky
Infliximab for Grade III/IV ICI Nephritis Clinical and Translational Evidence
Acute interstitial nephritis (AIN) is a common presentation of immune checkpoint inhibitor (ICI) toxicity. Increased TNF-α expression has been observed in ICI-induced AIN. In this study, we compared…
buff.ly
October 31, 2025 at 10:01 PM
International environmental impact of chronic kidney disease care
#openaccess
#nephsky
International environmental impact of chronic kidney disease care
Data reporting the environmental impact of the overall chronic kidney disease (CKD) care pathway are limited.
buff.ly
October 31, 2025 at 7:00 PM
Polygenic risk scores predicting estimated GFR validated with iohexol clearance
#openaccess
#nephsky
Polygenic risk scores predicting estimated GFR validated with iohexol clearance
Genome-wide association studies (GWAS) have identified hundreds of single nucleotide variants (SNV) associated with estimated GFR (eGFR). eGFR has been used as a proxy phenotype due to the complexity…
buff.ly
October 31, 2025 at 5:00 PM
Prevalence of skin cancers in kidney transplant recipients - one-center experience
#nephsky
Frontiers | Prevalence of skin cancers in kidney transplant recipients - one-center experience
IntroductionNon-melanoma skin cancers (NMSCs) are the most common neoplasms that occur in solid organ transplant recipients (SOTRs). Squamous cell carcinoma ...
buff.ly
October 30, 2025 at 12:02 PM
Incidence and predictors of hyperkalemia after subtotal parathyroidectomy in pediatric chronic dialysis patients with secondary hyperparathyroidism: a retrospective cohort study
#openaccess
#nephsky
Incidence and predictors of hyperkalemia after subtotal parathyroidectomy in pediatric chronic dialysis patients with secondary hyperparathyroidism: a retrospective cohort study - BMC Nephrology
Background Hyperkalemia is a life-threatening electrolyte complication reported sporadically in adults on chronic dialysis and secondary hyperparathyroidism (SHPT) after parathyroidectomy (PTX), but…
buff.ly
October 30, 2025 at 12:01 AM