aspneph.bsky.social
@aspneph.bsky.social
Association between intellectual disability and autism spectrum disorder with kidney failure
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Association between intellectual disability and autism spectrum disorder with kidney failure - Pediatric Nephrology
Background Evidence regarding the risk of incident kidney failure based on developmental disabilities remains scarce. Accordingly, we examined the risk of kidney failure in individuals with…
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February 6, 2026 at 2:00 AM
Potential implications of subclinical hypervolemia, identified by a multiparametric approach, in causing left ventricular hypertrophy in clinically euvolemic children on dialysis: a prospective longitudinal pilot study
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Potential implications of subclinical hypervolemia, identified by a multiparametric approach, in causing left ventricular hypertrophy in clinically euvolemic children on dialysis: a prospective longitudinal pilot study - Pediatric Nephrology
Background Fluid overload in children undergoing dialysis can lead to serious cardiac complications, i.e., left ventricular hypertrophy (LVH) and cardiac dysfunction. Studies investigating the…
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February 5, 2026 at 11:00 PM
Incidence and outcomes of stage 3 acute kidney injury in the setting of pediatric trauma: a trauma quality improvement program analysis
Incidence and outcomes of stage 3 acute kidney injury in the setting of pediatric trauma: a trauma quality improvement program analysis - Pediatric Nephrology
Background Acute Kidney Injury (AKI) increases morbidity and mortality risk, yet data in pediatric trauma are limited. This study evaluated the incidence of Kidney Disease: Improving Global Outcomes…
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February 1, 2026 at 9:00 PM
Early postnatal changes in serum creatinine from birth to peak and subsequent decline in preterm neonates
Early postnatal changes in serum creatinine from birth to peak and subsequent decline in preterm neonates - Pediatric Nephrology
Background In preterm neonates, the postnatal course of serum creatinine (sCr) is influenced by maternal sCr levels and physiological changes. While transient postnatal increases have been reported,…
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February 1, 2026 at 8:15 PM
Consanguinity-linked genetic variants in Algerian patients with steroid-resistant nephrotic syndrome: a familial study
Consanguinity-linked genetic variants in Algerian patients with steroid-resistant nephrotic syndrome: a familial study - Pediatric Nephrology
Background Steroid-resistant nephrotic syndrome (SRNS) is a severe glomerular disorder frequently progressing to kidney failure, particularly in children. Data on the genetic landscape of SRNS in…
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February 1, 2026 at 7:00 PM
Fibrocystin/polyductin (FPC): new functional insights into ARPKD pathogenesis revealed by informatics, comparative genomics, and model systems
Fibrocystin/polyductin (FPC): new functional insights into ARPKD pathogenesis revealed by informatics, comparative genomics, and model systems - Pediatric Nephrology
Autosomal recessive polycystic kidney disease (ARPKD) is the prototype of the hepato-renal fibrocystic diseases, a subset of the broader ciliopathy disorders. As a severe form of PKD, ARPKD typically…
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February 1, 2026 at 3:12 PM
T-cell lymphoblastic lymphoma presenting with type B lactic acidosis and acute kidney injury in an adolescent
T-cell lymphoblastic lymphoma presenting with type B lactic acidosis and acute kidney injury in an adolescent - Pediatric Nephrology
Acute kidney injury (AKI) in children is a major cause of morbidity and mortality and is most commonly associated with dehydration, sepsis, or nephrotoxic exposures. In rare instances, however,…
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January 31, 2026 at 4:00 PM
Comparison of creatinine- and cystatin C–based definitions of acute kidney injury in neonates with congenital diaphragmatic hernia
Comparison of creatinine- and cystatin C–based definitions of acute kidney injury in neonates with congenital diaphragmatic hernia - Pediatric Nephrology
Background Acute kidney injury (AKI) is a frequent complication in critically ill neonates and is associated with adverse outcomes. Infants with congenital diaphragmatic hernia (CDH) are particularly…
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January 31, 2026 at 2:49 PM
Arterial stiffening in children with early chronic kidney disease is associated with blood pressure but not decline in kidney function: a longitudinal study from the HOT-KID cohort
Arterial stiffening in children with early chronic kidney disease is associated with blood pressure but not decline in kidney function: a longitudinal study from the HOT-KID cohort - Pediatric Nephrology
Background Children with chronic kidney disease (CKD) are at risk of hypertension and increased arterial stiffness. We examined the roles of blood pressure (BP) and kidney function in development of…
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January 30, 2026 at 11:00 PM
Clinical phenotypes and severity stratification in pediatric diethylene glycol poisoning: a latent class analysis of the Gambia acute kidney injury outbreak.
Clinical phenotypes and severity stratification in pediatric diethylene glycol poisoning: a latent class analysis of the Gambia acute kidney injury outbreak - Pediatric Nephrology
Background Between June and September 2022, an outbreak of acute kidney injury (AKI) among children in The Gambia caused 66 deaths among 82 cases, linked to medicines contaminated with diethylene…
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January 30, 2026 at 7:15 PM
Identification of monogenic variants in steroid-resistant and steroid-sensitive nephrotic syndrome
Identification of monogenic variants in steroid-resistant and steroid-sensitive nephrotic syndrome - Pediatric Nephrology
Background Steroid-resistant nephrotic syndrome (SRNS) constitutes the second most common cause of chronic kidney disease (CKD) in children. A monogenic cause can be identified in approximately 25%…
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January 30, 2026 at 5:00 PM
Plasma-saliva correlations for total and unbound mycophenolic acid and its glucuronide in children with nephrotic syndrome
Plasma-saliva correlations for total and unbound mycophenolic acid and its glucuronide in children with nephrotic syndrome - Pediatric Nephrology
Background For mycophenolic acid (MPA), therapeutic drug monitoring (TDM) is recommended due to its complex pharmacokinetics. A non-invasive TDM approach using saliva is promising due to its…
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January 30, 2026 at 2:36 PM
Beyond genetics: how environmental stressors drive pediatric hypertension risk (review)
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Beyond genetics: how environmental stressors drive pediatric hypertension risk - Pediatric Nephrology
Abstract Pediatric hypertension is increasing in prevalence and is associated with cardiovascular and kidney outcomes in adulthood. Beyond traditional contributors such as obesity and kidney disease,…
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January 30, 2026 at 11:35 AM
Kidney and blood pressure sequelae after pediatric extracorporeal membrane oxygenation: a secondary analysis of the Kidney Injury During Membrane Oxygenation pediatric ECMO cohort
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Kidney and blood pressure sequelae after pediatric extracorporeal membrane oxygenation: a secondary analysis of the Kidney Injury During Membrane Oxygenation pediatric ECMO cohort - Pediatric Nephrology
Background Acute kidney injury (AKI) is common in children treated with extracorporeal membrane oxygenation (ECMO) and is associated with increased morbidity and mortality. AKI may also increase the…
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January 26, 2026 at 7:02 PM
Corticosteroids augment cyclosporine nephrotoxicity in pediatric nephrotic syndrome: potential role of alternatively activated macrophages
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Corticosteroids augment cyclosporine nephrotoxicity in pediatric nephrotic syndrome: potential role of alternatively activated macrophages - Pediatric Nephrology
Background Cyclosporine A (CsA) is an effective steroid-sparing agent for steroid-dependent nephrotic syndrome (SDNS); however, long-term use can cause chronic kidney injury (CsA nephropathy). We…
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January 26, 2026 at 1:02 PM
Case report: Successful treatment of severe, refractory polyomavirus disease with partially HLA-matched donor-derived BKPyV-specific T cells in a pediatric kidney recipient
Successful treatment of severe, refractory polyomavirus disease with partially HLA-matched donor-derived BKPyV-specific T cells in a pediatric kidney recipient - Pediatric Nephrology
BK polyomavirus–associated nephropathy is a significant therapeutic challenge in kidney transplant recipients, often leading to allograft dysfunction. We report on a 12-year-old male kidney…
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January 25, 2026 at 10:01 PM
Hospitalization burden in children on dialysis: insights from the Italian Registry of Pediatric Chronic Dialysis (IRPCD)
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Hospitalization burden in children on dialysis: insights from the Italian Registry of Pediatric Chronic Dialysis (IRPCD) - Pediatric Nephrology
Background Children receiving kidney replacement therapy frequently face complications resulting in recurrent hospitalizations. This nationwide retrospective observational study, conducted using data…
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January 25, 2026 at 12:01 AM
Neuraminidase activity in pediatric nephrotic syndrome
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Neuraminidase activity in pediatric nephrotic syndrome - Pediatric Nephrology
Pediatric Nephrology -
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January 24, 2026 at 7:00 PM
Exergaming as a promising approach to promote physical activity in children and adolescents during hemodialysis?
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#nephsky
Exergaming as a promising approach to promote physical activity in children and adolescents during hemodialysis? - Pediatric Nephrology
Pediatric Nephrology -
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January 24, 2026 at 2:01 PM
Oral liposomal iron vs. oral iron polymaltose in children with chronic kidney disease iron deficiency anemia: a cross-over study
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#anemiaofckd
Oral liposomal iron vs. oral iron polymaltose in children with chronic kidney disease iron deficiency anemia: a cross-over study - Pediatric Nephrology
Background Limited data exist on the use of novel iron therapies in children with chronic kidney disease (CKD). We conducted a cross-over study to compare iron polymaltose complex (IPC) and liposomal…
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January 24, 2026 at 12:00 AM
APOL1 kidney risk variants and outcomes in children with congenital anomalies of the kidney and urinary tract
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APOL1 kidney risk variants and outcomes in children with congenital anomalies of the kidney and urinary tract - Pediatric Nephrology
Background APOL1 high-risk variants predispose to chronic kidney disease (CKD) in individuals of African genetic ancestry due to podocyte toxicity. As congenital anomalies of the kidney and urinary…
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January 23, 2026 at 3:01 PM
Dialysis modality and mortality of the Contemporary Infant and Neonatal Dialysis (COINED) Cohort: a Pediatric Nephrology Research Consortium (PNRC) study
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Dialysis modality and mortality of the Contemporary Infant and Neonatal Dialysis (COINED) Cohort: a Pediatric Nephrology Research Consortium (PNRC) study - Pediatric Nephrology
Background Recent technologic advances in neonatal dialysis have changed current dialysis practices. The goal of this study was to define demographics, diagnoses, initial dialysis modality, modality…
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January 23, 2026 at 1:00 AM