José Costa Pereira
@josetiago.bsky.social
Neuroscience| Neurobiology of pain | University of Porto
📍Porto, Portugal
📍Porto, Portugal
Pinned
José Costa Pereira
@josetiago.bsky.social
· May 23
www.mdpi.com
🔬Excited to share our new review: “The Power of Movement: How Exercise Influences Chemotherapy-Induced Peripheral Neuropathy” just published in Biomedicines!
Exercise as medicine for CIPN? Maybe… 🏋🏽
Full read here: www.mdpi.com/2227-9059/13...
Exercise as medicine for CIPN? Maybe… 🏋🏽
Full read here: www.mdpi.com/2227-9059/13...
🔬Excited to share our new review: “The Power of Movement: How Exercise Influences Chemotherapy-Induced Peripheral Neuropathy” just published in Biomedicines!
Exercise as medicine for CIPN? Maybe… 🏋🏽
Full read here: www.mdpi.com/2227-9059/13...
Exercise as medicine for CIPN? Maybe… 🏋🏽
Full read here: www.mdpi.com/2227-9059/13...
www.mdpi.com
May 23, 2025 at 7:16 AM
🔬Excited to share our new review: “The Power of Movement: How Exercise Influences Chemotherapy-Induced Peripheral Neuropathy” just published in Biomedicines!
Exercise as medicine for CIPN? Maybe… 🏋🏽
Full read here: www.mdpi.com/2227-9059/13...
Exercise as medicine for CIPN? Maybe… 🏋🏽
Full read here: www.mdpi.com/2227-9059/13...
Reposted by José Costa Pereira
Breathing isn’t just for life—it’s a brain pacemaker!
This excellent review reveals how each breath sends sensory waves that globally synchronize neural networks (with implications for "functional connectivity")
Must‑read 👉 doi.org/10.1038/s415...
www.nature.com/articles/s41...
This excellent review reveals how each breath sends sensory waves that globally synchronize neural networks (with implications for "functional connectivity")
Must‑read 👉 doi.org/10.1038/s415...
www.nature.com/articles/s41...
Global coordination of brain activity by the breathing cycle - Nature Reviews Neuroscience
Synchrony between neuronal activity and the respiratory cycle has been observed in numerous brain regions and across many species. Tort et al. discuss the mechanisms by which brain activity is modulat...
www.nature.com
April 17, 2025 at 8:10 AM
Breathing isn’t just for life—it’s a brain pacemaker!
This excellent review reveals how each breath sends sensory waves that globally synchronize neural networks (with implications for "functional connectivity")
Must‑read 👉 doi.org/10.1038/s415...
www.nature.com/articles/s41...
This excellent review reveals how each breath sends sensory waves that globally synchronize neural networks (with implications for "functional connectivity")
Must‑read 👉 doi.org/10.1038/s415...
www.nature.com/articles/s41...
Reposted by José Costa Pereira
Pain-related input from the ventrolateral periaqueductal gray recruits BarCrh, reduces ascending nociceptive transmission.activates spinal dynorphin neurons to mediate analgesia.. a pontine inhibitory descending pathway powerfully controls nocifensive sensory input to the brain.
tinyurl.com/bdht38hy
tinyurl.com/bdht38hy
A pontine center in descending pain control
The pain experience is modulated by descending pathways. Using an intersectional strategy,
Li et al. map anatomical and molecular-spatial features of nociceptive descending
pathways. Their findings un...
www.cell.com
March 28, 2025 at 2:49 PM
Pain-related input from the ventrolateral periaqueductal gray recruits BarCrh, reduces ascending nociceptive transmission.activates spinal dynorphin neurons to mediate analgesia.. a pontine inhibitory descending pathway powerfully controls nocifensive sensory input to the brain.
tinyurl.com/bdht38hy
tinyurl.com/bdht38hy
Reposted by José Costa Pereira
New @science.org
Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading to weight loss
www.science.org/doi/10.1126/...
Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading to weight loss
www.science.org/doi/10.1126/...
Hedonic eating is controlled by dopamine neurons that oppose GLP-1R satiety
Hedonic eating is defined as food consumption driven by palatability without physiological need. However, neural control of palatable food intake is poorly understood. We discovered that hedonic eatin...
www.science.org
March 27, 2025 at 6:17 PM
New @science.org
Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading to weight loss
www.science.org/doi/10.1126/...
Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading to weight loss
www.science.org/doi/10.1126/...
Reposted by José Costa Pereira
Can we use brain scans to identify biologically distinct "autisms"? And If so, how?
In our latest cross-species study 🐭👨 with @iitalk.bsky.social we dive into these questions!
Find out more here 👇👇
www.biorxiv.org/content/10.1...
Thread below 🧵 1/n
In our latest cross-species study 🐭👨 with @iitalk.bsky.social we dive into these questions!
Find out more here 👇👇
www.biorxiv.org/content/10.1...
Thread below 🧵 1/n
March 6, 2025 at 11:18 AM
Can we use brain scans to identify biologically distinct "autisms"? And If so, how?
In our latest cross-species study 🐭👨 with @iitalk.bsky.social we dive into these questions!
Find out more here 👇👇
www.biorxiv.org/content/10.1...
Thread below 🧵 1/n
In our latest cross-species study 🐭👨 with @iitalk.bsky.social we dive into these questions!
Find out more here 👇👇
www.biorxiv.org/content/10.1...
Thread below 🧵 1/n
Reposted by José Costa Pereira
A 5 de janeiro de 1932 nascia Umberto Eco
👉 Recorda este artigo sobre o escritor, filósofo e linguista italiano:https://comunidadeculturaearte.com/umberto-eco-o-academico-sabio/
👉 Recorda este artigo sobre o escritor, filósofo e linguista italiano:https://comunidadeculturaearte.com/umberto-eco-o-academico-sabio/
January 5, 2025 at 10:48 AM
A 5 de janeiro de 1932 nascia Umberto Eco
👉 Recorda este artigo sobre o escritor, filósofo e linguista italiano:https://comunidadeculturaearte.com/umberto-eco-o-academico-sabio/
👉 Recorda este artigo sobre o escritor, filósofo e linguista italiano:https://comunidadeculturaearte.com/umberto-eco-o-academico-sabio/
Reposted by José Costa Pereira
"Odeio festas de Ano novo. Estão todos desesperados para se divertirem. Tentam comemorar de algum modo patético. Comemorar o quê? Um passo mais perto da sepultura?"
Filme "Whatever Works" (2009)
Filme "Whatever Works" (2009)
December 30, 2024 at 8:29 AM
"Odeio festas de Ano novo. Estão todos desesperados para se divertirem. Tentam comemorar de algum modo patético. Comemorar o quê? Um passo mais perto da sepultura?"
Filme "Whatever Works" (2009)
Filme "Whatever Works" (2009)
Reposted by José Costa Pereira
Para o jantar de família👇
December 24, 2024 at 9:40 AM
Para o jantar de família👇
Isto devia arrepiar as pessoas!
Repito o que tenho dito: a extrema-direita não é perigosa quando chega ao poder, é quando consegue que o poder se chegue a ela. É quando as coisas que defende deixam de parecer extremistas.
Hoje, na Mouraria, durante o debate sobre o acesso dos estrangeiros ao SNS.
O resultado do espetáculo que a foto mostra está na TSF: uma detenção, "várias armas", 4600 euros e artigos contrafeitos. Vamos fingir que não percebemos o que se está a passar?
O resultado do espetáculo que a foto mostra está na TSF: uma detenção, "várias armas", 4600 euros e artigos contrafeitos. Vamos fingir que não percebemos o que se está a passar?
December 20, 2024 at 9:15 AM
Isto devia arrepiar as pessoas!
“Ser cientista é uma função de quão intensa e profunda é a sua curiosidade sobre o mundo que o rodeia”
Entrevista. Nuno Maulide: “Ser cientista é uma função de quão intensa e profunda é a sua curiosidade sobre o mundo que o rodeia”
comunidadeculturaearte.com/entrevista-n...
comunidadeculturaearte.com/entrevista-n...
Entrevista. Nuno Maulide: “Ser cientista é uma função de quão intensa e profunda é a sua curiosidade sobre o mundo que o rodeia”
Nuno Maulide é um químico e divulgador de ciência português. Nasceu em Lisboa e licenciou-se em Química pelo Instituto Superior […]
comunidadeculturaearte.com
December 16, 2024 at 9:58 PM
“Ser cientista é uma função de quão intensa e profunda é a sua curiosidade sobre o mundo que o rodeia”
Reposted by José Costa Pereira
Early-life adversity mediates a thalamo-amgydalar circuit dysfunction underlying chronic pain and anxiety https://www.biorxiv.org/content/10.1101/2024.12.13.628438v1
December 16, 2024 at 9:15 AM
Early-life adversity mediates a thalamo-amgydalar circuit dysfunction underlying chronic pain and anxiety https://www.biorxiv.org/content/10.1101/2024.12.13.628438v1
Nunca esquecer!
Celebram-se hoje os 76 anos da Declaração Universal dos Direitos do Homem
December 10, 2024 at 7:46 AM
Nunca esquecer!
Reposted by José Costa Pereira
"É preciso criar histórias em que o vencedor não é o mais poderoso.”
December 3, 2024 at 8:55 AM
"É preciso criar histórias em que o vencedor não é o mais poderoso.”
Reposted by José Costa Pereira
When you switch the order of the co-firsts
December 1, 2024 at 7:07 AM
When you switch the order of the co-firsts
Reposted by José Costa Pereira
BOOM! Re-upping our Pain Research Starter Pack since so many people have joined this glorious place in the past week. If you are not on the list and want to be added, let me know and I will add you... I have been doing my best to keep this updated.
#painresearch
go.bsky.app/KboKNhg
#painresearch
go.bsky.app/KboKNhg
November 26, 2024 at 7:11 PM
BOOM! Re-upping our Pain Research Starter Pack since so many people have joined this glorious place in the past week. If you are not on the list and want to be added, let me know and I will add you... I have been doing my best to keep this updated.
#painresearch
go.bsky.app/KboKNhg
#painresearch
go.bsky.app/KboKNhg
Reposted by José Costa Pereira
Cool new paper from Camilla Svensson’s team and a reminder to not give up understanding NGF signsling for pain treatment! journals.lww.com/pain/fulltex...
Sex-dependent effects of the targeted nerve growth factor... : PAIN
inflammation-induced pain-related behaviors and bone loss. The hNGF-R100E mutation did not alter the nerve fiber density in the sciatic nerve, ankle joint synovium, and skin of naïve mice. Withdrawal ...
journals.lww.com
November 19, 2024 at 11:31 AM
Cool new paper from Camilla Svensson’s team and a reminder to not give up understanding NGF signsling for pain treatment! journals.lww.com/pain/fulltex...
Reposted by José Costa Pereira
Let's unleash the axonal growth cones for this #Fluorescencefriday ! #neuroscience #Liveimaging #microscopy #Axonguidance
November 15, 2024 at 7:19 AM
Let's unleash the axonal growth cones for this #Fluorescencefriday ! #neuroscience #Liveimaging #microscopy #Axonguidance
Reposted by José Costa Pereira
Two BOOM!s in one day: www.nature.com/articles/s41... This flies totally in the face of what I think I know about visceral pain, but when evidence challenges your preconceived notions, maybe it is time to consider changing my gastric pain view.
A vagus nerve dominant tetra-synaptic ascending pathway for gastric pain processing - Nature Communications
Gastric pain has limited treatment options and the nociceptive ascending pathway remains largely unclear. Here, the authors identify a glutamatergic tetra-synaptic NTS–LPB–PVT–PL circuit that provides...
www.nature.com
November 14, 2024 at 2:54 PM
Two BOOM!s in one day: www.nature.com/articles/s41... This flies totally in the face of what I think I know about visceral pain, but when evidence challenges your preconceived notions, maybe it is time to consider changing my gastric pain view.
Reposted by José Costa Pereira
My students convincing me to use google docs instead of word
November 11, 2024 at 12:04 PM
My students convincing me to use google docs instead of word
Reposted by José Costa Pereira
Hard to overstate how pleased I am that the FlyWire consortium converted our FAFB ("Full Adult Fly Brain") EM volume into a connectome, and that the resulting science has been (and will be) so impactful. Thanks to everyone involved. #neuroscience www.nature.com/immersive/d4...
The FlyWire connectome: neuronal wiring diagram of a complete fly brain
Artificial intelligence and human expertise meet to generate a map of all the connections in the fly brain. The resource is already being used by experimentalists and theoreticians to further our unde...
www.nature.com
October 2, 2024 at 7:08 PM
Hard to overstate how pleased I am that the FlyWire consortium converted our FAFB ("Full Adult Fly Brain") EM volume into a connectome, and that the resulting science has been (and will be) so impactful. Thanks to everyone involved. #neuroscience www.nature.com/immersive/d4...