Josien
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joscience.bsky.social
Josien
@joscience.bsky.social
#astrocytes fanatic. Studying the stars of the brain in sensory processing. Also SciCom, books, music and running.
Reposted by Josien
Does our very human ability to anticipate #musical structure exist at birth? @robertabianco.bsky.social @giacomonovembre.bsky.social &co show that #newborns encode #rhythmic (but not melodic) expectations based on statistical regularities in real #music @plosbiology.org plos.io/4kqKVWg
February 6, 2026 at 5:25 PM
Reposted by Josien
PSA for all #microglia lovers: certain Iba1 antibodies (see our new paper below for details) label not only microglia, but also vasopressin neurons, at least in mice. Brain region and species matter. A friendly reminder to always validate your antibodies! 🔬

www.eneuro.org/content/13/2...
A Common Iba1 Antibody Labels Vasopressin Neurons in Mice
There are a wide variety of commercially available antibodies for labeling microglial cells based on different protein targets, as well as antibodies for the same protein target made in different spec...
www.eneuro.org
February 3, 2026 at 9:36 PM
Reposted by Josien
Europe loves to lecture the world about values, but morals without power is just vibes. We regulate AI we don’t build, sell handbags instead of hardware, and rely on others for our security and energy.

If we really believe in liberal democracy, we’d better be willing to back it up.
February 3, 2026 at 1:17 PM
Reposted by Josien
What's the relation between voltage and calcium in dendrites? Xiang Wu studied this in CA2 hippocampal pyramidal cells in behaving mice. www.biorxiv.org/content/10.6...
January 21, 2026 at 7:51 PM
Reposted by Josien
Reposted by Josien
I’m very happy to share the latest from my lab published in @Nature

Hippocampal neurons that initially encode reward shift their tuning over the course of days to precede or predict reward.

Full text here:
rdcu.be/eY5nh
January 14, 2026 at 9:32 PM
Reposted by Josien
Excited to be giving the van Vreeswijk Theoretical Neuroscience Seminar this Wednesday, Jan 14, where I'll talk about "Computation Through Neuronal-Synaptic Dynamics"!
www.wwtns.online
Home | Neuroscience | World Wide Theoretical Neuroscience Seminar
WWTNS is a weekly digital seminar on Zoom targeting the theoretical neuroscience community. Its aim is to be a platform to exchange ideas among theoreticians.
www.wwtns.online
January 10, 2026 at 7:45 PM
Reposted by Josien
Distinct endocannabinoids specifically signal to astrocytes or neurons in the adult mouse hippocampus
www.nature.com/articles/s41...
Distinct endocannabinoids specifically signal to astrocytes or neurons in the adult mouse hippocampus - Nature Neuroscience
Distinct endocannabinoids signal to either astrocytes or neurons, evoking contrasting regulation of synaptic function. This works reveals the high degree of complexity of neuronal and astrocytic signa...
www.nature.com
January 1, 2026 at 7:46 PM
Reposted by Josien
For decades, imaging has forced the same trade-off:
Set a frame rate → sacrifice resolution or field of view to go fast.

We break that rule

Using an EVENT-BASED CAMERA, we record neural activity without frames. Signals are captured only where and when they occur:

www.biorxiv.org/content/10.6...
Ultrafast Frame-Free Imaging of Neural Activity with Event Cameras
Frame-based fluorescence imaging has long defined how neural activity is optically measured. This approach requires acquiring all pixels within an image, regardless of whether they carry meaningful ne...
www.biorxiv.org
January 10, 2026 at 1:41 PM
Reposted by Josien
Astrocytes control oxytocin-based maternal behavior via connexin 30 https://www.biorxiv.org/content/10.64898/2026.01.09.698569v1
January 10, 2026 at 7:15 AM
Reposted by Josien
Violence, death and stolen land: people need to know the true cost of an avocado | Claudia Ignacio Álvarez
Violence, death and stolen land: people need to know the true cost of an avocado | Claudia Ignacio Álvarez
Behind the west’s huge appetite for the fruit lies the dark reality of environmental destruction and Indigenous exploitation in Mexico
www.theguardian.com
January 6, 2026 at 7:19 AM
Reposted by Josien
this is my Oy Division t-shirt
2025 goes down as the ~3rd-warmest year on record (based on ERA5).

Like in 2024, every single day this past year was warmer than the average of even the most recent reference period (1991-2020).
January 5, 2026 at 3:50 AM
Reposted by Josien
iGluSnFR4 is now available @natmethods.nature.com

www.nature.com/articles/s41...

Glutamate indicators with increased sensitivity and tailored deactivation rates 🧪
Glutamate indicators with increased sensitivity and tailored deactivation rates - Nature Methods
iGluSnFR4f and iGluSnFR4s are the latest generation of genetically encoded glutamate sensors. They are advantageous for detecting rapid dynamics and large population activity, respectively, as demonst...
www.nature.com
December 23, 2025 at 1:21 PM
Reposted by Josien
Members of WarsawGliaComm Publish 🔬🧬🧪
Proud to highlight the new study from Anna Malik Lab in NatComm! Brilliant insights into how astrocyte distress triggers brain pathology via δ-secretase. Check it out!
👉 www.nature.com/articles/s41...
#neuroscience #glia #Warsaw
Astrocytes distress triggers brain pathology through induction of δ secretase in a murine model of Alzheimer’s disease - Nature Communications
The role of astrocytes in Alzheimer’s disease pathology remains insufficiently characterized. Here, the authors show that aggravated astrocyte response to Aβ causes brain inflammation, and amyloid and...
www.nature.com
December 18, 2025 at 8:29 AM
Reposted by Josien
New episode alert!
Discover episode 5 of Qrieux: #Sleep better thanks to #astrocytes.
Featuring Félix Bellier, Léana Razaghi & Armelle Rancillac.

Available in FR with FR/GB subtitles.
Watch now 👉 youtu.be/nHTbSGvEpGM?...

#Neuroscience #Qrieux @psl-univ.bsky.social @inserm.fr @cirbcdf.bsky.social
Qrieux, la série - Épisode 5 - Mieux dormir grâce aux astrocytes
YouTube video by PSL-Qlife
youtu.be
November 5, 2025 at 8:08 AM
Reposted by Josien
The fruit fly visual system gets a glow-up during pupal development. A new study reveals how non-neuronal calcium activity fine-tunes the boundaries between each portion of the compound eye.

By @lauren-schneider.com

#neuroskyence

www.thetransmitter.org/developmenta...
December 12, 2025 at 4:43 PM
Reposted by Josien
In 2017, a lawsuit uncovered emails from Monsanto that suggested its employees helped ghostwrite an influential paper that claimed to find no evidence the company’s widely used herbicide, Roundup, caused cancer.

Now, the paper has been retracted. https://scim.ag/4iG55KO
Journal retracts weed killer study backed by Monsanto, citing ‘serious ethical concerns’
Highly cited paper was used as evidence that the widely used herbicide Roundup is safe
scim.ag
December 8, 2025 at 5:11 PM
Reposted by Josien
The temperature in central the Netherlands over the past 320 years. Clearly shows that we're already well over 2 degrees of warming here. This year is heading for 11.5°C again.
This coming Monday and Tuesday, we'll even have that average, in December...
Gemiddelde temperatuur centraal Nederland vanaf 1706, 3, 11 en 30 jaars gemiddelde op maandgemiddelde.
December 6, 2025 at 4:20 PM
Reposted by Josien
Nature Sci Rep publishes incoherent AI slop. eLife publishes a paper which the reviewers didn't agree with, making all the comments and responses public with thoughtful commentary. One of these journals got delisted by Web of Science for quality concerns from not doing peer review. Guess which one?
November 27, 2025 at 1:35 PM
Reposted by Josien
Il y a près de trois ans, Libération révélait qu’un agent du CNRS était suspecté d’avoir harcelé une neurobiologiste et d’avoir dissimulé une caméra dans les toilettes pour femmes. Les victimes dénoncent depuis l’extrême lenteur de l’enquête malgré les nombreuses preuves matérielles.
Le «corbeau» du Collège de France, sa caméra dans les toilettes et l’enquête qui patine
Il y a près de trois ans, «Libération» révélait qu’un agent du CNRS était suspecté d’avoir harcelé une neurobiologiste et dissimulé une caméra dans les toilettes pour femmes. Les victimes dénoncent depuis l’extrême lenteur de l’enquête.
www.liberation.fr
November 25, 2025 at 7:17 PM
Reposted by Josien
We look forward to seeing you Tomorrow Nov 26 at 2PM for the 2nd IGN SYMPOSIUM. A time for Glia related Science, with open and live discussion with the Italian glia community. See you Tomorrow!!! 
unipd.zoom.us/j/83647074227?…

Italianglianetwork.c
om
Home | Italian Glia Network
Italian Glia Network (IGN) was founded in 2023 by a group of passionate scientists dedicated to glia research. IGN has the MISSION of creating a community of scientists interested in glial biology. IG...
Italianglianetwork.com
November 25, 2025 at 12:59 PM
Reposted by Josien
Schiphol heeft enorme groeiplannen tot 2050. Deze petitie is een reactie erop, want een pas op de plaats is gepast: de planeet warmt op, de overlast groeit steeds verder en de natuur is toe aan herstel. Zeg daarom NEE tegen de groei van Schiphol.

toekomstschiphol.petities.nl
Verander de toekomstplannen van Schiphol
Schiphol heeft enorme groeiplannen tot 2050 (https://nieuws.schiphol.nl/schiphol-kiest-in-toekomstplannen-voor-kwaliteit-en-balans/). Deze petitie is een reactie erop, want een pas op de plaats is gep...
toekomstschiphol.petities.nl
November 25, 2025 at 9:09 AM
Reposted by Josien
Image screening is going to fail. We need audit trails for data provenance.
I tried an even harder example on Gemini Pro image generation and this is quite scary/amazing. I asked for a microscopy image of around 20 HeLa cells, GFP tagged 20% nuclear, 10% membrane, +1 nuclear staining, + overlap. Image below and prompt in the following post.
November 22, 2025 at 4:21 PM