Abhi Aggarwal
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abhiaggarwal.bsky.social
Abhi Aggarwal
@abhiaggarwal.bsky.social
Medical Student at University of Calgary
Former researcher at the Allen Institute, Seattle

Medicine | Protein Engineering | Biosensors | Fluorescent Proteins | iGluSnFR | Imaging

Views are my own. Posts are not medical advice.
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🚨iGluSnFR4 is finally out!🚨🧪

We present iGluSnFR4f and 4s, a novel pair of genetically-encoded glutamate indicators designed for high-fidelity imaging of synaptic activity in the living brain. ⬇️

www.biorxiv.org/content/10.1...

🎥 Below: iGluSnFR4s detecting minis in cultures w/ TTX

#Neuroscience
#OCaMP is now on bioRxiv and reagents are available on #Addgene! 🧪

A sensitive orange fluorescent calcium ion indicator for imaging neural activity

www.biorxiv.org/content/10.1...
A sensitive orange fluorescent calcium ion indicator for imaging neural activity
Genetically encoded calcium indicators (GECIs) are vital tools for fluorescence-based visualization of neuronal activity with high spatial and temporal resolution. However, current highest-performance...
www.biorxiv.org
July 31, 2025 at 7:34 PM
🚨iGluSnFR4 is finally out!🚨🧪

We present iGluSnFR4f and 4s, a novel pair of genetically-encoded glutamate indicators designed for high-fidelity imaging of synaptic activity in the living brain. ⬇️

www.biorxiv.org/content/10.1...

🎥 Below: iGluSnFR4s detecting minis in cultures w/ TTX

#Neuroscience
March 25, 2025 at 12:10 PM
Reposted by Abhi Aggarwal
High-speed video showing glutamate lighting up as it’s released in synapses, visualizing the neurotransmitters of the brain with the fluorescent indicator protein iGluSnFR3.

Credit: Allen Institute, Aggarwal et al.
February 1, 2025 at 11:14 PM
First sky post 🦋 Sharing some vibrant iGluSnFR3 minis in cultured neurons!
November 12, 2024 at 10:36 PM