Oh. My. God. I did not realize this article cited “ai” use in science in its reasoning.
These tools are incredible, it’s true. AlphaFold is straight up an example of how AI can actually work for us. But even that starts with a scientist with an idea!
These tools are incredible, it’s true. AlphaFold is straight up an example of how AI can actually work for us. But even that starts with a scientist with an idea!
None of the examples in this article are “restarting the world’s idea machine.” They are AI tools helping scientists automate rote or routine tasks.
December 16, 2025 at 4:02 AM
Oh. My. God. I did not realize this article cited “ai” use in science in its reasoning.
These tools are incredible, it’s true. AlphaFold is straight up an example of how AI can actually work for us. But even that starts with a scientist with an idea!
These tools are incredible, it’s true. AlphaFold is straight up an example of how AI can actually work for us. But even that starts with a scientist with an idea!
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I understand that a lot of folks have been misled by fear-mongering and powerful regressive voices but it’s still astonishing to me that so many have fallen for the idea that oppressively policing other people’s gender identity and expression could in any way be part of an enlightened future.
December 13, 2025 at 5:49 PM
I understand that a lot of folks have been misled by fear-mongering and powerful regressive voices but it’s still astonishing to me that so many have fallen for the idea that oppressively policing other people’s gender identity and expression could in any way be part of an enlightened future.
No Children but it’s me singing to my manuscript
December 12, 2025 at 7:59 PM
No Children but it’s me singing to my manuscript
As someone who has lost a beloved mentor to pancreatic cancer, the idea we could be so close to a cure and then lose it is gutting.
A tiny trial in New York has shown that personalized mRNA vaccines can provoke massive, lasting immune responses against pancreatic cancer, even as sweeping federal cuts now threaten the fragile labs required to produce them.
theintellectualistofficial.substack.com/p/a-breakthr...
theintellectualistofficial.substack.com/p/a-breakthr...
December 12, 2025 at 5:53 PM
As someone who has lost a beloved mentor to pancreatic cancer, the idea we could be so close to a cure and then lose it is gutting.
The Dispossessed.
omg. Kat Abughazaleh just posted that if she's elected, she'll swear in on a copy of Octavia Butler's Parable of the Sower.
If you were elected to public office (never mind whether you'd ever actually run), what book would you swear in on?
If you were elected to public office (never mind whether you'd ever actually run), what book would you swear in on?
December 11, 2025 at 12:23 AM
The Dispossessed.
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It’s also plainly absurd that someone just happened to discover the true meaning of the common law that just evaded everyone else for 800 years in a few weeks of work. I don’t even know what to do with that.
the idea that a handful of conservative legal scholars have an understanding that should supersede a settlement affirmed my generations of american is astoundingly arrogant, and the idea that trump — or any president — can unilaterally overturn that settlement is just despotism
December 7, 2025 at 7:38 PM
It’s also plainly absurd that someone just happened to discover the true meaning of the common law that just evaded everyone else for 800 years in a few weeks of work. I don’t even know what to do with that.
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It starts with knowing the truth. Don’t allow yourselves to be gaslit into believing this is a real question.
December 6, 2025 at 2:44 PM
It starts with knowing the truth. Don’t allow yourselves to be gaslit into believing this is a real question.
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Hey, hey, RFK
How many kids did you kill today?
How many kids did you kill today?
December 5, 2025 at 6:35 PM
Hey, hey, RFK
How many kids did you kill today?
How many kids did you kill today?
“Overwhelming” an immune system through too many vaccines is a ridiculous idea. We have millions of immune cells and adaptive responses are by definition specific. AND do you know how many antigens we’re naturally exposed to on a daily basis???
Show me data that demonstrates more vaccines = "bad" for someone. Current research shows multiple vaccines given at once are safe and don't "overwhelm" a child's immune system.
December 5, 2025 at 5:18 PM
“Overwhelming” an immune system through too many vaccines is a ridiculous idea. We have millions of immune cells and adaptive responses are by definition specific. AND do you know how many antigens we’re naturally exposed to on a daily basis???
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Also, Bill Cassidy owns this and should never be taken seriously again.
December 5, 2025 at 4:36 PM
Also, Bill Cassidy owns this and should never be taken seriously again.
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The sheer ability of the majority of this ACIP to misinterpret and fail to explain basic scientific data is stunning. The sky is blue and they would say its gold everytime.
December 5, 2025 at 3:51 PM
The sheer ability of the majority of this ACIP to misinterpret and fail to explain basic scientific data is stunning. The sky is blue and they would say its gold everytime.
From an immunologist perspective, I also worry that fewer doses will not generate the memory B cell response needed for longterm protection. HebB titers can become undetectable, but Bmems are known to respond quickly to challenge and still confer protection.
It is NOT a large assumption that the HepB vaccine needs 3 doses. The clinical trial showed that over 90% of children achieved the 10-unit titre of HepBsAg AFTER 3 DOSES. The data shows this.
December 5, 2025 at 3:55 PM
From an immunologist perspective, I also worry that fewer doses will not generate the memory B cell response needed for longterm protection. HebB titers can become undetectable, but Bmems are known to respond quickly to challenge and still confer protection.
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I would rather have a world where we all trust each other and accept that a few people will take advantage of it than a world where folks have to perform disability constantly in order to get the help they need. Let kids have an extra 30 minutes on the test, jesus fucking christ
December 2, 2025 at 8:32 PM
I would rather have a world where we all trust each other and accept that a few people will take advantage of it than a world where folks have to perform disability constantly in order to get the help they need. Let kids have an extra 30 minutes on the test, jesus fucking christ
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This is my poorly-drawn meme pitch for you all to read Asunder by @kerstinhall.bsky.social aka My Favorite Book I Read This Year And It's Not Even Close. I actually NEED more people to read this book so we can yap about it together!!!!!!
November 23, 2025 at 10:07 PM
This is my poorly-drawn meme pitch for you all to read Asunder by @kerstinhall.bsky.social aka My Favorite Book I Read This Year And It's Not Even Close. I actually NEED more people to read this book so we can yap about it together!!!!!!
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who is following you dorks that you feel the need to repeatedly post that mtg is not on the side of the angels. it feels like spending a lot of time telling people not to eat hams they find on the ground
November 22, 2025 at 2:16 AM
who is following you dorks that you feel the need to repeatedly post that mtg is not on the side of the angels. it feels like spending a lot of time telling people not to eat hams they find on the ground
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Happy men day to the trans dudes, the kind dudes, the dudes who are doing their best, the dudes who love and support their friends, the dudes who kiss the homies goodnight, and zohran mamdani
November 19, 2025 at 11:55 PM
Happy men day to the trans dudes, the kind dudes, the dudes who are doing their best, the dudes who love and support their friends, the dudes who kiss the homies goodnight, and zohran mamdani
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Setting aside the obvious reality that many people develop medical conditions unrelated to behaviors (eg, type 1 diabetes), 80-90% of our health is shaped by non-medical factors like poverty, housing, education, transportation & access to healthy food. The personal responsibility frame is unhelpful.
Markwayne Mullin: "Reward people for being healthy. Think about this. Healthcare is the only industry that you're not rewarded for taking care of your responsibility. If you think about homeowners insurance, if you're within 500 feet of a fire hydrant, your insurance goes down."
November 19, 2025 at 6:30 PM
Setting aside the obvious reality that many people develop medical conditions unrelated to behaviors (eg, type 1 diabetes), 80-90% of our health is shaped by non-medical factors like poverty, housing, education, transportation & access to healthy food. The personal responsibility frame is unhelpful.
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NEW:
In 2024, Tierra Walker was sick and getting sicker. She was also pregnant.
She knew abortion was illegal in Texas, but thought there was an exception for women like her, whose health was at risk. Doctors told her there was no emergency.
Then she died.
www.propublica.org/article/texa...
In 2024, Tierra Walker was sick and getting sicker. She was also pregnant.
She knew abortion was illegal in Texas, but thought there was an exception for women like her, whose health was at risk. Doctors told her there was no emergency.
Then she died.
www.propublica.org/article/texa...
“Ticking Time Bomb”: A Pregnant Mother Kept Getting Sicker. She Died After She Couldn’t Get an Abortion in Texas.
Walker is one of several women ProPublica found with underlying health conditions who died when they couldn’t access abortions.
www.propublica.org
November 19, 2025 at 11:08 AM
NEW:
In 2024, Tierra Walker was sick and getting sicker. She was also pregnant.
She knew abortion was illegal in Texas, but thought there was an exception for women like her, whose health was at risk. Doctors told her there was no emergency.
Then she died.
www.propublica.org/article/texa...
In 2024, Tierra Walker was sick and getting sicker. She was also pregnant.
She knew abortion was illegal in Texas, but thought there was an exception for women like her, whose health was at risk. Doctors told her there was no emergency.
Then she died.
www.propublica.org/article/texa...
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i’d be more comfortable with the olivia nuzzi coverage if every story was headlined something like “seduced by a guy who eats roadkill: the story of an extremely stupid lady”
November 14, 2025 at 7:02 PM
i’d be more comfortable with the olivia nuzzi coverage if every story was headlined something like “seduced by a guy who eats roadkill: the story of an extremely stupid lady”
Food, healthcare, and shelter are basic human rights (this shouldn’t be “woke”).
We should have universal basic income. I want creatives to be able to thrive in the world and not just survive.
We should have universal basic income. I want creatives to be able to thrive in the world and not just survive.
"my least woke opinion is---"
That's enough. We've had enough people indulging in the "thrill of a little conservatism", as a treat. Of considering reactionary thought to be a salacious and taboo in a world descending into reactionary mania.
Give me your MOST woke opinions. We're bringing it back.
That's enough. We've had enough people indulging in the "thrill of a little conservatism", as a treat. Of considering reactionary thought to be a salacious and taboo in a world descending into reactionary mania.
Give me your MOST woke opinions. We're bringing it back.
November 14, 2025 at 3:29 PM
Food, healthcare, and shelter are basic human rights (this shouldn’t be “woke”).
We should have universal basic income. I want creatives to be able to thrive in the world and not just survive.
We should have universal basic income. I want creatives to be able to thrive in the world and not just survive.
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Yooo! Someone You Can Build A Nest In was picked as a Kindle Gold Box Deal! For today only, get it for just $4.99.
A shapeshifting monster *accidentally* falls in love with the woman who's hunting her. We've all been there, right?
A shapeshifting monster *accidentally* falls in love with the woman who's hunting her. We've all been there, right?
Someone You Can Build a Nest In
Amazon.com: Someone You Can Build a Nest In eBook : Wiswell, John: Kindle Store
www.amazon.com
November 13, 2025 at 10:21 AM
Yooo! Someone You Can Build A Nest In was picked as a Kindle Gold Box Deal! For today only, get it for just $4.99.
A shapeshifting monster *accidentally* falls in love with the woman who's hunting her. We've all been there, right?
A shapeshifting monster *accidentally* falls in love with the woman who's hunting her. We've all been there, right?
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I think there is little scientific value in the genomes of famous people, and in this case, obvious and preventable harms. No one needed to look at polygenic scores for different diseases. They are, as Adam rightly claims in this 🧵, not how the diseases are diagnosed, not indicated by historical…
Right. Hitler's DNA. Brace yourselves for a deluge of misinformation and bad science.
I'm in Australia, so do get in touch if you want some expert debunking.
I'm in Australia, so do get in touch if you want some expert debunking.
November 13, 2025 at 6:17 PM
I think there is little scientific value in the genomes of famous people, and in this case, obvious and preventable harms. No one needed to look at polygenic scores for different diseases. They are, as Adam rightly claims in this 🧵, not how the diseases are diagnosed, not indicated by historical…
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A reminder that this anti-trans panic is 100% bullshit and exactly none of our country’s problems are related to someone expressing their gender identity and everyone who isn’t a hate-filled weirdo knows it.
November 10, 2025 at 1:16 PM
A reminder that this anti-trans panic is 100% bullshit and exactly none of our country’s problems are related to someone expressing their gender identity and everyone who isn’t a hate-filled weirdo knows it.
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The average SNAP benefit per month is $177 a person.
The average ACA benefit per month is up to $550 a person.
People want us to hold the line for a reason. This is not a matter of appealing to a base. It’s about people’s lives.
And working people want leaders whose word means something to them.
The average ACA benefit per month is up to $550 a person.
People want us to hold the line for a reason. This is not a matter of appealing to a base. It’s about people’s lives.
And working people want leaders whose word means something to them.
November 10, 2025 at 1:49 AM
The average SNAP benefit per month is $177 a person.
The average ACA benefit per month is up to $550 a person.
People want us to hold the line for a reason. This is not a matter of appealing to a base. It’s about people’s lives.
And working people want leaders whose word means something to them.
The average ACA benefit per month is up to $550 a person.
People want us to hold the line for a reason. This is not a matter of appealing to a base. It’s about people’s lives.
And working people want leaders whose word means something to them.
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I finished reading the @kateelliottsff.bsky.social duology The Witch Roads / The Nameless Land, and if you've been sleeping on those books, put them on your TBR immediately.
SO. GOOD.
SO. GOOD.
November 7, 2025 at 9:10 PM
I finished reading the @kateelliottsff.bsky.social duology The Witch Roads / The Nameless Land, and if you've been sleeping on those books, put them on your TBR immediately.
SO. GOOD.
SO. GOOD.