Guy Leonard
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guyleonard.bsky.social
Guy Leonard
@guyleonard.bsky.social
Bioinformatician w/ Tom Richards & Team at @oxfordbiology.bsky.social

Homebrewer. WSET Beer Level 2.

Rejoiner πŸ‡ͺπŸ‡ΊπŸ€πŸ‡¬πŸ‡§

AI is not 'inevitable', resist its uncritical adoption.

Constant politics-doom ruined the other place.
Pinned
De novo genome sequence assembly of the model algal endosymbiont Micractinium conductrix derived from its host Paramecium bursaria 186b.

Guy Leonard, Irma Vitonyte, Fiona R Savory, Erika M Hansson, Duncan D Cameron, Michael Brockhurst, Thomas A Richards
bioRxiv doi: doi.org/10.64898/202...
De novo genome sequence assembly of the model algal endosymbiont Micractinium conductrix derived from its host Paramecium bursaria 186b
Endosymbiosis is a major driver of evolutionary innovation and underpins the function of diverse ecosystems. The origins and evolution of endosymbiosis are challenging to study experimentally due to t...
doi.org
Reposted by Guy Leonard
This Saturday morning we have Chris Wheat (@chriswheat.bsky.social) on stage, with Lies, damn lies... and genomics! πŸ“ŠπŸ“‰β‰οΈ Can we trust the results we are generating? Always good to doubt yourself and be aware of your biases and possible errors 🧐
January 17, 2026 at 10:08 AM
Reposted by Guy Leonard
I have a PhD in Microbiology. I work on understanding fungal and protist pathogens, their function, how the environment they live in shapes them especially under stress.
Also I like to communicate science and train the nex gen of experts. πŸ§ͺ🧫
How many good mothers on Bluesky ARE the expert??

I’ll start: I have a PhD in ecology. I’m a science communicator: an award-winning creator, strategist, and impact producer. I make stuff for the internet that brings people together πŸ§ͺ

Your turn! GO OFF, GOOD MOMS OF BLUESKY
HHS Secretary RFK Jr: "This idea that you should trust the experts, a good mother doesn't do that"
January 16, 2026 at 6:25 PM
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From theory to practice, we move on to the lab on Genome Annotation with Katharina Hoff (@katharinahoff.bsky.social) πŸ‘©πŸ»β€πŸ’»πŸ™ŒπŸ½ #evomics2026
January 16, 2026 at 6:34 PM
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We continue the day in the Town Theatre with Genome Annotation, a lecture by Katharina Hoff (@katharinahoff.bsky.social) πŸ™ŒπŸ½πŸ§¬πŸ™†πŸ»β€β™€οΈ #evomics2026
January 16, 2026 at 2:40 PM
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Olga Vinnere Pettersson giving a lecture on everything one has to take into account when planning a sequencing project πŸ§ͺπŸ§¬πŸ—’πŸ“¦ #evomics2026
January 16, 2026 at 2:38 PM
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We finish the day with another practical session by Petr Daněček (@petrdanecek.bsky.social) on Variant Calling πŸ§¬πŸ’»πŸ™†πŸ»β€β™€οΈ #evomics2026
January 15, 2026 at 6:11 PM
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Morning lecture by Marcela Uliano-Silva (@marcelauliano.bsky.social) on Wonders of Genome Assembly! How does a de novo genome sequencing project looks like? What are the steps to follow to get the best genome assembly possible? She covers it all! πŸ™†πŸ»β€β™€οΈπŸ§¬πŸ’» #evomics2026
January 15, 2026 at 1:15 PM
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Camilla Santos takes over after the genome assembly sessions, to cover Genome Assembly Curation, the session includes a live demo on how to manually curate a genome assembly πŸ§¬πŸ’»πŸ–±lots of cool Hi-C map plots! πŸ“‰ #evomics2026
January 15, 2026 at 1:21 PM
The great regurgitation engine is only a paradox if you haven't stopped to actually think for more than 20 seconds.
January 15, 2026 at 9:23 AM
Reposted by Guy Leonard
Analyses of hundreds of thousands of papers in the natural sciences reveal a paradox: scientists who use AI tools produce more research but on a more confined set of topics

go.nature.com/458k7Ub
AI tools boost individual scientists but could limit research as a whole
Analyses of hundreds of thousands of papers in the natural sciences reveal a paradox: scientists who use AI tools produce more research but on a more confined set of topics.
go.nature.com
January 15, 2026 at 9:13 AM
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Exercise time! 🀩 Participants generating their own de Bruijn graph! πŸ“πŸ‘©πŸ»β€πŸ’»
January 14, 2026 at 1:56 PM
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A classic of the Workshop on Genomics, the Genome Assembly lecture by Camille Marchet (@camillemrcht.bsky.social) and Antoine Limasset (@npmalfoy.bsky.social), teaching us about overlapping sequences and genome assembly graphs πŸ§¬πŸ’» #evomics2026
January 14, 2026 at 1:40 PM
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Sequence alignment lecture at the Town Theatre this morning! πŸ§¬πŸ’»πŸ’Ž #evomics2026
January 14, 2026 at 1:21 PM
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We end day 2 with an evening session by Petr Daněček (@petrdanecek.bsky.social) on Essential File Types in Genomics. Very important to understand the format and structure of the files we will analyse! πŸ™ŒπŸ½πŸ’»πŸ‘€ #evomics2026
January 13, 2026 at 7:20 PM
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We continued with an Introduction to Unix, by MercΓ¨ Montoliu Nerin (@mmontonerin.bsky.social), to make sure all the participants get comfortable in the computer environment in which they will spend many hours in the coming days! πŸ‘©πŸ»β€πŸ’» #evomics2026
January 13, 2026 at 7:15 PM
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First sessions in our computer lab location, the House or Prelate of ČeskΓ½ Krumlov πŸ™†πŸ»β€β™€οΈ Starting with an introduction to the AMIs, the cloud, and computing, by Guy Leonard (@guyleonard.bsky.social) β˜οΈπŸ’» #evomics2026
January 13, 2026 at 7:08 PM
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Do you want to hear about our recent progress in training gene finder Tiberius and integrating extrinsic evidence into genome annotation? Don’t miss my talk today at 11:30 in Pacific A at #PAG33
January 13, 2026 at 2:23 PM
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Kick-off lecture with Olga Vinnere Pettersson, covering sequencing technologies 🧬πŸ§ͺπŸ’» #evomics2026
January 12, 2026 at 1:29 PM
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Our town coordinator, Daniel Kintzl, introducing everything one needs to know about ČeskΓ½ Krumlov, the wonderful location where we will spend the next two weeks πŸ€—β˜ƒοΈ #evomics2026
January 12, 2026 at 9:22 AM
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The workshop director, @josieparis.bsky.social introducing the 2026 Workshop on Genomics to our participants! πŸ™†πŸ»β€β™€οΈ #evomics2026
January 12, 2026 at 8:08 AM
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Our TAs are ready in the Zlaty Andel hotel reception to hand out badges and direct our participants to the dinner reception! Looking forward to meeting all of you!! πŸ€— #evomics2026
January 11, 2026 at 4:48 PM
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The workshop team is on site, testing labs and getting everything ready for the 2026 Workshop on Genomics! πŸ™ŒπŸ½πŸ‘©πŸ»β€πŸ’» #evomics2026
January 9, 2026 at 10:15 AM
Reposted by Guy Leonard
Four new entries in my collection of A.I.-generated images πŸ€–πŸŽ¨ in academic journals:

bit.ly/academic-slop, version 2.
Pulled From the Trough: Slop Images in Academic Journals
This project collects images created using generative artificial intelligence (gen AI) that have appeared in academic journals.If you run across examples of gen AI images in journals or books - whethe...
bit.ly
January 5, 2026 at 2:59 PM
Reposted by Guy Leonard
Cerveza Polar, Venezuela, c1950.
January 3, 2026 at 4:21 PM
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I rarely get this angry, but this pisses me off.

Just because a bunch of fools started calling what they do "cognitive science" when it isn't science, doesn't mean that what we do as cognitive scientists isn't.

Go read Von Eckhardt's "What is cognitive science?" if you doubt me.
December 31, 2025 at 9:36 PM