Gul Muneer
@gulmuneer.bsky.social
Postdoctoral Research Associate
#SingleCellPhosphoProteomics #Phosphoproteomics
#SingleCellProteomics #Proteomics
#MassSpec #DigitalArtist
#SingleCellPhosphoProteomics #Phosphoproteomics
#SingleCellProteomics #Proteomics
#MassSpec #DigitalArtist
Reposted by Gul Muneer
News in Proteomics Research blog post | Lessons learned migrating proteomics to HPC (high performance computing) environments! proteomicsnews.blogs...
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#proteomics #prot-other
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#proteomics #prot-other
Lessons learned migrating proteomics to HPC (high performance computing) environments!
Sometimes this blog is just what I learn as I'm going through learning something for myself - and this is clearly one of those posts. One...
proteomicsnews.blogspot.com
May 7, 2025 at 2:00 PM
News in Proteomics Research blog post | Lessons learned migrating proteomics to HPC (high performance computing) environments! proteomicsnews.blogs...
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#proteomics #prot-other
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#proteomics #prot-other
Reposted by Gul Muneer
Mass Spectrometry-Based Proteomics for Next-Generation Precision Oncology #MassSpectromRev analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10....
Mass Spectrometry‐Based Proteomics for Next‐Generation Precision Oncology
Cancer is the leading cause of death worldwide characterized by patient heterogeneity and complex tumor microenvironment. While the genomics-based testing has transformed modern medicine, the challen...
analyticalsciencejournals.onlinelibrary.wiley.com
April 24, 2025 at 8:19 AM
Mass Spectrometry-Based Proteomics for Next-Generation Precision Oncology #MassSpectromRev analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10....
Reposted by Gul Muneer
Ok this is just insane. Such an amazing application of DVP. Having collaborated on some mitosis related projects I had dreamed of doing exactly this kind of experiment. AI/ML segmentation + laser capture has so many unique applications. This is the tip of the iceberg.
A Morpho-Proteomic Atlas of Mitosis at Sub-Minute Resolution www.biorxiv.org/cont...
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#proteomics #prot-preprint
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#proteomics #prot-preprint
April 11, 2025 at 11:26 AM
Ok this is just insane. Such an amazing application of DVP. Having collaborated on some mitosis related projects I had dreamed of doing exactly this kind of experiment. AI/ML segmentation + laser capture has so many unique applications. This is the tip of the iceberg.
Reposted by Gul Muneer
I wrote a very long blog post about AI writing. I hope you'll read it.
meresophistry.substack.com/p/the-mental...
meresophistry.substack.com/p/the-mental...
The mental tyranny of AI writing
An arduously long blog post
meresophistry.substack.com
March 29, 2025 at 7:10 PM
I wrote a very long blog post about AI writing. I hope you'll read it.
meresophistry.substack.com/p/the-mental...
meresophistry.substack.com/p/the-mental...
I rebooted my brain by not reading a proteomics paper this afternoon. It is not a proteomics paper, is it?
March 28, 2025 at 8:42 AM
I rebooted my brain by not reading a proteomics paper this afternoon. It is not a proteomics paper, is it?
Reposted by Gul Muneer
Thinking about “what if’s”… if I had to move on, I think a good next job would be one where I get to tackle the really big questions, like why does that first batch of pancakes not brown the same as the ensuing batches? People need to know!
March 17, 2025 at 10:34 AM
Thinking about “what if’s”… if I had to move on, I think a good next job would be one where I get to tackle the really big questions, like why does that first batch of pancakes not brown the same as the ensuing batches? People need to know!
Reposted by Gul Muneer
Interested in using proteomics in your ECM research? Come hear from 2 excellent researchers on how you can apply this to your work!
March 18th, the link the register is below ☺️
March 18th, the link the register is below ☺️
Are you ready to delve into the mass-spec of it all??? Join us to learn more on how to incorporate proteomics in your ECM research from Cassandra Clift and @rachelcahalane.bsky.social !!! March 18, 5pm CET (12pm New York) !!! Register now: forms.gle/9wAguRkZu4Ru...
March 10, 2025 at 12:35 PM
Interested in using proteomics in your ECM research? Come hear from 2 excellent researchers on how you can apply this to your work!
March 18th, the link the register is below ☺️
March 18th, the link the register is below ☺️
Reposted by Gul Muneer
I keep hearing from people who have either listened to or watched this podcast.
They often tell me that my perspective was new to them as they did not realize the fundamental differences between proteomics and transcriptomics.
youtu.be/sGW4cFee1IY?...
They often tell me that my perspective was new to them as they did not realize the fundamental differences between proteomics and transcriptomics.
youtu.be/sGW4cFee1IY?...
Unveiling Proteins: The Future Of Single-Cell Proteomics With Professor Nikolai Slavov
YouTube video by ARK Invest
youtu.be
March 1, 2025 at 3:00 PM
I keep hearing from people who have either listened to or watched this podcast.
They often tell me that my perspective was new to them as they did not realize the fundamental differences between proteomics and transcriptomics.
youtu.be/sGW4cFee1IY?...
They often tell me that my perspective was new to them as they did not realize the fundamental differences between proteomics and transcriptomics.
youtu.be/sGW4cFee1IY?...
Reposted by Gul Muneer
Comprehensive coverage of spatial proteomics in The Scientist, highlighting how deep visual proteomics is advancing our understanding of disease. Great to share our perspective alongside another pioneer in the field!
www.the-scientist.com/spatial-prot...
www.the-scientist.com/spatial-prot...
Spatial Proteomics and Deep Visual Proteomics: A Revolution in Cell Biology
Spatial proteomics creates detailed protein profiles of cells. This article covers spatial proteomics methods, deep visual proteomics, and their applications.
www.the-scientist.com
February 24, 2025 at 1:30 PM
Comprehensive coverage of spatial proteomics in The Scientist, highlighting how deep visual proteomics is advancing our understanding of disease. Great to share our perspective alongside another pioneer in the field!
www.the-scientist.com/spatial-prot...
www.the-scientist.com/spatial-prot...
Reposted by Gul Muneer
Insights from the #Proteome are becoming increasingly powerful and predictive. Expect low cost #Proteomics to be leveraged in our multimodal future of optimized health, early disease detection, and more targeted, precision medicine.
My latest segment on TechNation Health
My latest segment on TechNation Health
BioTech Nation ... with Dr. Moira Gunn | The Mystery of "Dark" Proteins... Dr. Daniel Kraft, Tech Nation Health Chief Correspondent
This week on BioTech Nation, Dr. Daniel Kraft explores the discovery of
www.biotechnation.com
February 21, 2025 at 2:51 PM
Insights from the #Proteome are becoming increasingly powerful and predictive. Expect low cost #Proteomics to be leveraged in our multimodal future of optimized health, early disease detection, and more targeted, precision medicine.
My latest segment on TechNation Health
My latest segment on TechNation Health
Reposted by Gul Muneer
🚀 Orbitraps on the move! The #MassSpec community rarely talks about moving Orbitraps, but a new study shows they can collect high-res data while in motion. Have you used an #Orbitrap outside the lab? Let’s start the conversation—share your experience! 🔬⚡ Read more: www.karsa.fi/resources/mo...
Mobile Orbitrap Mass Spectrometry: Stability and Performance in Motion – Karsa
Historically, Orbitrap mass spectrometers have been considered large, power-intensive, and lab-bound instruments -- but times have changed!
www.karsa.fi
February 21, 2025 at 2:49 PM
🚀 Orbitraps on the move! The #MassSpec community rarely talks about moving Orbitraps, but a new study shows they can collect high-res data while in motion. Have you used an #Orbitrap outside the lab? Let’s start the conversation—share your experience! 🔬⚡ Read more: www.karsa.fi/resources/mo...
Reposted by Gul Muneer
First time I’ve transported a mass spec in the boot of the car. Pumped down almost ready for a collaborative project. Now just need to find an Agilent 5973/5/7 inert source (G2591B) if anyone has a spare they could donate to a collaborative project.
February 20, 2025 at 3:53 AM
Reposted by Gul Muneer
Illumina will enter the Spatial-Omics market in 2026 with Connected Multiomics (ICM) open.substack.com/pub/albertvi...
Illumina will enter the Spatial-Omics market in 2026 with Connected Multiomics (ICM)
Illumina announced two hours ago that they have a new spatial technology program aiming at mapping complex tissues and understand cellular behaviour at a high-throughput scale.
open.substack.com
February 19, 2025 at 4:55 PM
Illumina will enter the Spatial-Omics market in 2026 with Connected Multiomics (ICM) open.substack.com/pub/albertvi...
Reposted by Gul Muneer
🚨Amidst all the uncertainty at NIH Welcome Leap just launched an important new $50M program in Women’s Health👩🏻🔬🧠
CARE focuses on the link between Alzheimer’s and perimenopausal hormonal changes wellcomeleap.org/care/
Note: full indirects!
Please share widely to support women’s health 🙏🏼
CARE focuses on the link between Alzheimer’s and perimenopausal hormonal changes wellcomeleap.org/care/
Note: full indirects!
Please share widely to support women’s health 🙏🏼
CARE Program Details | Wellcome Leap: Unconventional Projects. Funded at Scale.
NEW $50M Program in Women's Health care Cutting Alzheimer's Risk through EndocrinologyWe are pleased to announce the selected performers.Sabine Vollstädt-Klein, Central Institute of Mental Health ...
wellcomeleap.org
February 14, 2025 at 12:11 AM
🚨Amidst all the uncertainty at NIH Welcome Leap just launched an important new $50M program in Women’s Health👩🏻🔬🧠
CARE focuses on the link between Alzheimer’s and perimenopausal hormonal changes wellcomeleap.org/care/
Note: full indirects!
Please share widely to support women’s health 🙏🏼
CARE focuses on the link between Alzheimer’s and perimenopausal hormonal changes wellcomeleap.org/care/
Note: full indirects!
Please share widely to support women’s health 🙏🏼
Reposted by Gul Muneer
📣📣 first update on our BSPR2025 meeting takingnplace 7-9th july. We reveal our amazing plenary speakers.
@slavov-n.bsky.social will talk about single cell proteomics
@vadim-demichev.bsky.social talking about DIA-NN
@epetsalaki.bsky.social on computational biology focus
@slavov-n.bsky.social will talk about single cell proteomics
@vadim-demichev.bsky.social talking about DIA-NN
@epetsalaki.bsky.social on computational biology focus
February 13, 2025 at 12:05 PM
📣📣 first update on our BSPR2025 meeting takingnplace 7-9th july. We reveal our amazing plenary speakers.
@slavov-n.bsky.social will talk about single cell proteomics
@vadim-demichev.bsky.social talking about DIA-NN
@epetsalaki.bsky.social on computational biology focus
@slavov-n.bsky.social will talk about single cell proteomics
@vadim-demichev.bsky.social talking about DIA-NN
@epetsalaki.bsky.social on computational biology focus
Reposted by Gul Muneer
Our Deep Visual Proteomics workflow maps protein networks in bladder, prostate, seminal vesicle & lymph node Signet Ring Cell Carcinoma, revealing DNA damage response alterations & immune signatures that could guide therapy choice. Out now in NPJ Precision Oncology! rdcu.be/d8KyK
Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma
npj Precision Oncology - Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma
rdcu.be
February 6, 2025 at 8:06 AM
Our Deep Visual Proteomics workflow maps protein networks in bladder, prostate, seminal vesicle & lymph node Signet Ring Cell Carcinoma, revealing DNA damage response alterations & immune signatures that could guide therapy choice. Out now in NPJ Precision Oncology! rdcu.be/d8KyK
Reposted by Gul Muneer
Hi Skeeps, if you are in the London area and would like me to speak at your university or company, I will be in London on Thursday April 10 and Friday April 11.
Looking for talks that can offer some travel/lodging reimbursement.
Looking for talks that can offer some travel/lodging reimbursement.
February 4, 2025 at 7:04 PM
Hi Skeeps, if you are in the London area and would like me to speak at your university or company, I will be in London on Thursday April 10 and Friday April 11.
Looking for talks that can offer some travel/lodging reimbursement.
Looking for talks that can offer some travel/lodging reimbursement.
Reposted by Gul Muneer
DIA-NN 2.0 is released! We consider it the biggest step forward in the history of DIA-NN. On modern LC-MS almost all identifications are now peptidoform-confident, with major improvements e.g. for phospho. Some other cool things too: github.com/vdemichev/Di...
Release DIA-NN 2.0 · vdemichev/DiaNN
We are excited to announce DIA-NN 2.0, the most significant milestone in the history of DIA-NN development.
Key Breakthroughs
Proteoform Confidence mode: DIA-NN 2.0 solves the long-standing chall...
github.com
January 29, 2025 at 9:04 AM
DIA-NN 2.0 is released! We consider it the biggest step forward in the history of DIA-NN. On modern LC-MS almost all identifications are now peptidoform-confident, with major improvements e.g. for phospho. Some other cool things too: github.com/vdemichev/Di...
Reposted by Gul Muneer
To the amazing government scientists and employees out there who protect our country and people - please hang in there - and thank you. You are appreciated and missed. We can’t wait to see and hear from you!! 🇺🇸
January 25, 2025 at 2:01 AM
To the amazing government scientists and employees out there who protect our country and people - please hang in there - and thank you. You are appreciated and missed. We can’t wait to see and hear from you!! 🇺🇸
Reposted by Gul Muneer
The Mann lab is here now, be sure to follow them.
Also the Bluesky proteomics migration is almost complete!
Also the Bluesky proteomics migration is almost complete!
Looking for rapid, deep & reproducible proteomics? Follow our @Nature protocol to get 7k proteins & 29k phosphosites in just 21 min! Complete #PASEF workflow using optimal dia-PASEF, synchro-PASEF & py_diAID. From method development to analysis. #TeamMassSpec @patiskowronek.bsky.social explains 👇
🚀 Robust and high sensitivity #proteomics: Our Nature protocol demystifies #PASEF workflows and provides ready-to-use dia-PASEF & synchro-PASEF methods. Find out how to achieve 7,000 protein groups or 29,000 phosphosites in 21min. Let's explore! #TeamMassSpec #Bruker doi.org/10.1038/s415... 1/🧵
January 22, 2025 at 12:00 PM
The Mann lab is here now, be sure to follow them.
Also the Bluesky proteomics migration is almost complete!
Also the Bluesky proteomics migration is almost complete!
Reposted by Gul Muneer
Do you want to explore the PTMs you identified in your last MS experiment in a fun, interactive way? Try it out on our PTMVision web server at ptmvision-tuevis.cs.uni-tuebingen.de and check out the new publication in JPR at doi.org/10.1021/acs....!
PTMVision
PTMVision: Interactive Visualization of Post Translational Modifications | Understanding the intricate landscape of post-translational
modifications (PTMs) is crucial for unraveling the co...
ptmvision-tuevis.cs.uni-tuebingen.de
January 21, 2025 at 4:02 PM
Do you want to explore the PTMs you identified in your last MS experiment in a fun, interactive way? Try it out on our PTMVision web server at ptmvision-tuevis.cs.uni-tuebingen.de and check out the new publication in JPR at doi.org/10.1021/acs....!
Reposted by Gul Muneer
You've heard of TIMS, but have you heard of TIMF?
Bruker's new patent describes a Trapped Ion Mobility Filter.
FAIMS selects a narrow range of ions (e.g. 2+ only), but TIMF allows you to exclude ions (1+), and keep ions below or above that mobility (2+ to 5+).
patentscope.wipo.int/search/en/de...
Bruker's new patent describes a Trapped Ion Mobility Filter.
FAIMS selects a narrow range of ions (e.g. 2+ only), but TIMF allows you to exclude ions (1+), and keep ions below or above that mobility (2+ to 5+).
patentscope.wipo.int/search/en/de...
January 20, 2025 at 11:15 AM
You've heard of TIMS, but have you heard of TIMF?
Bruker's new patent describes a Trapped Ion Mobility Filter.
FAIMS selects a narrow range of ions (e.g. 2+ only), but TIMF allows you to exclude ions (1+), and keep ions below or above that mobility (2+ to 5+).
patentscope.wipo.int/search/en/de...
Bruker's new patent describes a Trapped Ion Mobility Filter.
FAIMS selects a narrow range of ions (e.g. 2+ only), but TIMF allows you to exclude ions (1+), and keep ions below or above that mobility (2+ to 5+).
patentscope.wipo.int/search/en/de...
Reposted by Gul Muneer
We are here to announce that the British Society for Proteome Research is now fully on BlueSky. This will be our main social network, but we will also post on LinkedIn.
We are excited to interact with the proteomics community and we have lots of exciting news to share.
We are excited to interact with the proteomics community and we have lots of exciting news to share.
January 12, 2025 at 4:48 PM
We are here to announce that the British Society for Proteome Research is now fully on BlueSky. This will be our main social network, but we will also post on LinkedIn.
We are excited to interact with the proteomics community and we have lots of exciting news to share.
We are excited to interact with the proteomics community and we have lots of exciting news to share.
Reposted by Gul Muneer
Proteomics via NGS for UK Biobank will be conducted using the Olink® Explore HT proteomics platform and Ultima's UG 100™ sequencing platform, with the actual sequencing performed at the Regeneron Genetics Center (RGC), one of the world's largest human genetics sequencing and research facilities.
Ultima Genomics selected by UK Burbank Proteomics project
January 10, 2025 at 8:06 AM
Proteomics via NGS for UK Biobank will be conducted using the Olink® Explore HT proteomics platform and Ultima's UG 100™ sequencing platform, with the actual sequencing performed at the Regeneron Genetics Center (RGC), one of the world's largest human genetics sequencing and research facilities.