Grocott Lab
@grocottlab.bsky.social
Dr Tim Grocott's research group, University of East Anglia UK. 🐣 embryology & new adventures in human development via stem cells. Modelling in silico/vitro. Fascinated by signalling networks, patterning, all things early development and the eye.
Pinned
Grocott Lab
@grocottlab.bsky.social
· Mar 6
Need to electroporate and/or live image avian embryos? We hope our new preprint will help you get started:
www.biorxiv.org/content/10.1...
Open EGGbox: an open-source 3D-printed embryonic Gallus gallus toolbox for electroporation and culture/live imaging of avian embryos ex ovo
🧪🐣 #devbio
www.biorxiv.org/content/10.1...
Open EGGbox: an open-source 3D-printed embryonic Gallus gallus toolbox for electroporation and culture/live imaging of avian embryos ex ovo
🧪🐣 #devbio
Reposted by Grocott Lab
mSumireF a Monomeric Violet Fluorescent Protein:
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
January 8, 2026 at 6:15 PM
mSumireF a Monomeric Violet Fluorescent Protein:
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
Reposted by Grocott Lab
There is still over a week left to apply.
Please send your documents to maik.bischoff@uni-muenster.de
Please send your documents to maik.bischoff@uni-muenster.de
Join us to study developmental cell biology with a focus on cell migration and morphogenesis.
More info about our research:
www.bischofflab.com
Job posting and application details:
focalplane.biologists.com/cell-biology...
#Science #CellBio #DevBio #AcademicJobs #PhDJobs #PhDPosition #Drosophila
More info about our research:
www.bischofflab.com
Job posting and application details:
focalplane.biologists.com/cell-biology...
#Science #CellBio #DevBio #AcademicJobs #PhDJobs #PhDPosition #Drosophila
January 6, 2026 at 12:43 PM
There is still over a week left to apply.
Please send your documents to maik.bischoff@uni-muenster.de
Please send your documents to maik.bischoff@uni-muenster.de
Reposted by Grocott Lab
Throughout this work, we found it really helpful to organize our thinking along 'Marr's three levels of analysis':
1. the computational problem
2. the algorithmic solution
3. biophysical implementation
Check out our review laying out this conceptual framework here: buff.ly/NE4JEOA
1. the computational problem
2. the algorithmic solution
3. biophysical implementation
Check out our review laying out this conceptual framework here: buff.ly/NE4JEOA
Marr's three levels for embryonic development: information, dynamical systems, gene networks
Developmental patterning comprises processes that range from purely instructed, where external signals specify cell fates, to fully self-organized, where spatial patterns emerge autonomously through…
arxiv.org
January 5, 2026 at 8:00 AM
Throughout this work, we found it really helpful to organize our thinking along 'Marr's three levels of analysis':
1. the computational problem
2. the algorithmic solution
3. biophysical implementation
Check out our review laying out this conceptual framework here: buff.ly/NE4JEOA
1. the computational problem
2. the algorithmic solution
3. biophysical implementation
Check out our review laying out this conceptual framework here: buff.ly/NE4JEOA
Reposted by Grocott Lab
How can cells use information from neighboring cells to improve the spatial precision of morphogen patterns? 🤔
We show that cells can gain positional information by "talking" to their neighbors - how much depends critically on spatial correlations of the patterns.
buff.ly/w56OUJT
We show that cells can gain positional information by "talking" to their neighbors - how much depends critically on spatial correlations of the patterns.
buff.ly/w56OUJT
January 5, 2026 at 8:00 AM
How can cells use information from neighboring cells to improve the spatial precision of morphogen patterns? 🤔
We show that cells can gain positional information by "talking" to their neighbors - how much depends critically on spatial correlations of the patterns.
buff.ly/w56OUJT
We show that cells can gain positional information by "talking" to their neighbors - how much depends critically on spatial correlations of the patterns.
buff.ly/w56OUJT
Reposted by Grocott Lab
@devdynamics.bsky.social Welcome to Bluesky Developmental Dynamics, added to the Developmental Biology starter pack II.
You can also patch in to more #DevBio folks by checking out the first Developmental Biology start pack here:
go.bsky.app/M5AgJhn
You can also patch in to more #DevBio folks by checking out the first Developmental Biology start pack here:
go.bsky.app/M5AgJhn
November 16, 2024 at 11:20 PM
@devdynamics.bsky.social Welcome to Bluesky Developmental Dynamics, added to the Developmental Biology starter pack II.
You can also patch in to more #DevBio folks by checking out the first Developmental Biology start pack here:
go.bsky.app/M5AgJhn
You can also patch in to more #DevBio folks by checking out the first Developmental Biology start pack here:
go.bsky.app/M5AgJhn
Reposted by Grocott Lab
Morphogenesis & Organogenesis!
Part 1 (full) in the comments 👇
Comment if you'd like to be added (regardless of age or career stage!)
Please post your own biology-related starter packs using #BioStarterPacks
🧬🔬🪰🐟🐁🌱
Part 1 (full) in the comments 👇
Comment if you'd like to be added (regardless of age or career stage!)
Please post your own biology-related starter packs using #BioStarterPacks
🧬🔬🪰🐟🐁🌱
June 26, 2025 at 9:40 PM
Morphogenesis & Organogenesis!
Part 1 (full) in the comments 👇
Comment if you'd like to be added (regardless of age or career stage!)
Please post your own biology-related starter packs using #BioStarterPacks
🧬🔬🪰🐟🐁🌱
Part 1 (full) in the comments 👇
Comment if you'd like to be added (regardless of age or career stage!)
Please post your own biology-related starter packs using #BioStarterPacks
🧬🔬🪰🐟🐁🌱
Reposted by Grocott Lab
“This work highlights how dynamical systems theory and nonequilibrium thermodynamics provide powerful analytical techniques to study biological complexity.”
iopscience.iop.org/article/10.1...
iopscience.iop.org/article/10.1...
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iopscience.iop.org
December 21, 2025 at 3:40 AM
“This work highlights how dynamical systems theory and nonequilibrium thermodynamics provide powerful analytical techniques to study biological complexity.”
iopscience.iop.org/article/10.1...
iopscience.iop.org/article/10.1...
Reposted by Grocott Lab
This is now a published peer-reviewed paper, in which we show, for the first time (to my knowledge) an interaction and co-operation between SALL4 and BAF (SWI/SNF). Together, they induce neural crest fate early on, by priming thousands of enhancers in the neuroectoderm.
doi.org/10.1242/dev....
doi.org/10.1242/dev....
December 19, 2025 at 12:48 PM
This is now a published peer-reviewed paper, in which we show, for the first time (to my knowledge) an interaction and co-operation between SALL4 and BAF (SWI/SNF). Together, they induce neural crest fate early on, by priming thousands of enhancers in the neuroectoderm.
doi.org/10.1242/dev....
doi.org/10.1242/dev....
Reposted by Grocott Lab
#DBfeature 🐣
Unravelling early hematoendothelial development through the chick model: Insights and future perspectives
by Lydia Pouncey, Gi Fay Mok @gifaymok.bsky.social
www.sciencedirect.com/science/arti...
Unravelling early hematoendothelial development through the chick model: Insights and future perspectives
by Lydia Pouncey, Gi Fay Mok @gifaymok.bsky.social
www.sciencedirect.com/science/arti...
December 18, 2025 at 2:53 PM
#DBfeature 🐣
Unravelling early hematoendothelial development through the chick model: Insights and future perspectives
by Lydia Pouncey, Gi Fay Mok @gifaymok.bsky.social
www.sciencedirect.com/science/arti...
Unravelling early hematoendothelial development through the chick model: Insights and future perspectives
by Lydia Pouncey, Gi Fay Mok @gifaymok.bsky.social
www.sciencedirect.com/science/arti...
Reposted by Grocott Lab
I've spent all day struggling to write a single page of a popular science article. I bang away at a word processor; give up; start diagramming on paper. Take some notes; draft a few sentences in pen; return to the computer...and very slowly I figure out what I was trying to say in the first place.
December 16, 2025 at 11:41 PM
I've spent all day struggling to write a single page of a popular science article. I bang away at a word processor; give up; start diagramming on paper. Take some notes; draft a few sentences in pen; return to the computer...and very slowly I figure out what I was trying to say in the first place.
Reposted by Grocott Lab
Thank goodness for that. Something that shouldn’t have happened, happened. And now it’s set to unhappen. Great for students, great for research in general and great for Britain.
www.theguardian.com/world/2025/d...
www.theguardian.com/world/2025/d...
UK to rejoin EU’s Erasmus student exchange programme
Exclusive: British students will be able to participate in EU-wide scheme from January 2027, sources say
www.theguardian.com
December 17, 2025 at 8:19 AM
Thank goodness for that. Something that shouldn’t have happened, happened. And now it’s set to unhappen. Great for students, great for research in general and great for Britain.
www.theguardian.com/world/2025/d...
www.theguardian.com/world/2025/d...
Reposted by Grocott Lab
Please share 📢
We have a Postdoc position available here @uniofeastanglia.bsky.social to develop innovative genetic control strategies for insect agricultural pests in collaboration with @imperialcollegeldn.bsky.social
vacancies.uea.ac.uk/vacancies/19...
We have a Postdoc position available here @uniofeastanglia.bsky.social to develop innovative genetic control strategies for insect agricultural pests in collaboration with @imperialcollegeldn.bsky.social
vacancies.uea.ac.uk/vacancies/19...
December 15, 2025 at 9:35 AM
Please share 📢
We have a Postdoc position available here @uniofeastanglia.bsky.social to develop innovative genetic control strategies for insect agricultural pests in collaboration with @imperialcollegeldn.bsky.social
vacancies.uea.ac.uk/vacancies/19...
We have a Postdoc position available here @uniofeastanglia.bsky.social to develop innovative genetic control strategies for insect agricultural pests in collaboration with @imperialcollegeldn.bsky.social
vacancies.uea.ac.uk/vacancies/19...
Reposted by Grocott Lab
Hello, here is a review I wrote about how cells sometimes try to synchronise with surrounding cells so that they can do a good job of building tissues during development. It is called "Keeping up with the neighbours"
link.springer.com/article/10.1...
#DevBio 🧪
link.springer.com/article/10.1...
#DevBio 🧪
Keeping up with the neighbours: local synchronisation of cell fate decisions during development - EMBO Reports
Even before the advent of multicellular life, unicellular creatures would communicate with their neighbours to coordinate their behaviours. Multicellular organisms have the particular challenge of orc...
link.springer.com
December 11, 2025 at 3:19 PM
Hello, here is a review I wrote about how cells sometimes try to synchronise with surrounding cells so that they can do a good job of building tissues during development. It is called "Keeping up with the neighbours"
link.springer.com/article/10.1...
#DevBio 🧪
link.springer.com/article/10.1...
#DevBio 🧪
Reposted by Grocott Lab
At first glance, looks like a Gray–Scott reaction-diffusion
But it’s a fertilized starfish 🥚: proteins self-organizing into spiral waves across the membrane
Same dynamics seen in ❤️/🧠/🌊, even quantum fluids. Universality in action!
#ComplexSystems
news.mit.edu/2020/growth-...
But it’s a fertilized starfish 🥚: proteins self-organizing into spiral waves across the membrane
Same dynamics seen in ❤️/🧠/🌊, even quantum fluids. Universality in action!
#ComplexSystems
news.mit.edu/2020/growth-...
December 9, 2025 at 9:03 PM
At first glance, looks like a Gray–Scott reaction-diffusion
But it’s a fertilized starfish 🥚: proteins self-organizing into spiral waves across the membrane
Same dynamics seen in ❤️/🧠/🌊, even quantum fluids. Universality in action!
#ComplexSystems
news.mit.edu/2020/growth-...
But it’s a fertilized starfish 🥚: proteins self-organizing into spiral waves across the membrane
Same dynamics seen in ❤️/🧠/🌊, even quantum fluids. Universality in action!
#ComplexSystems
news.mit.edu/2020/growth-...
Reposted by Grocott Lab
Frog eye, frog eye. Can I have a confocal microscope to play on for 12 hrs a day again please? 👉👈🥺 🐸
December 9, 2025 at 7:58 PM
Frog eye, frog eye. Can I have a confocal microscope to play on for 12 hrs a day again please? 👉👈🥺 🐸
Reposted by Grocott Lab
Want to image cells protecting the embryo during early development? We're hiring! 1 Postdoc, 1 PhD student, and 1 Research Technician. Come to Barcelona! www.embryobioimaging.com
December 9, 2025 at 5:44 PM
Want to image cells protecting the embryo during early development? We're hiring! 1 Postdoc, 1 PhD student, and 1 Research Technician. Come to Barcelona! www.embryobioimaging.com
Reposted by Grocott Lab
Can we build a human?
Madeline Lancaster joined Brian Cox & a panel of experts for the @crick.ac.uk & BBC Studios podcast A Question of Science, to answer this question.
Find the episode here: www.lnk.to/AQOSBioengin...
#LMBintheNews
@cellbiol-mrclmb.bsky.social @lancasterlab.bsky.social
Madeline Lancaster joined Brian Cox & a panel of experts for the @crick.ac.uk & BBC Studios podcast A Question of Science, to answer this question.
Find the episode here: www.lnk.to/AQOSBioengin...
#LMBintheNews
@cellbiol-mrclmb.bsky.social @lancasterlab.bsky.social
December 4, 2025 at 2:41 PM
Can we build a human?
Madeline Lancaster joined Brian Cox & a panel of experts for the @crick.ac.uk & BBC Studios podcast A Question of Science, to answer this question.
Find the episode here: www.lnk.to/AQOSBioengin...
#LMBintheNews
@cellbiol-mrclmb.bsky.social @lancasterlab.bsky.social
Madeline Lancaster joined Brian Cox & a panel of experts for the @crick.ac.uk & BBC Studios podcast A Question of Science, to answer this question.
Find the episode here: www.lnk.to/AQOSBioengin...
#LMBintheNews
@cellbiol-mrclmb.bsky.social @lancasterlab.bsky.social
Reposted by Grocott Lab
Reciprocal interactions between EMT and BMP signalling drive collective cell invasion. https://www.biorxiv.org/content/10.64898/2025.12.02.691808v1
December 4, 2025 at 6:30 PM
Reciprocal interactions between EMT and BMP signalling drive collective cell invasion. https://www.biorxiv.org/content/10.64898/2025.12.02.691808v1
Reposted by Grocott Lab
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Development's Pathway to Independence Programme
Our grants support and encourage the sharing of knowledge throughout the community by facilitating international collaboration, event attendance and the organisation of scientific meetings, conference...
www.biologists.com
December 3, 2025 at 6:56 AM
Applications are open for @dev-journal.bsky.social 2026 Pathway to Independence (PI) programme, supporting postdocs applying for group leader positions:
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Mentoring
Profile raising
Leadership training
Network building
Spread the word...
www.biologists.com/grants/devel...
Reposted by Grocott Lab
We are hiring! Please submit your application by Dec. 5! We are a basic science department housed in the school of vet med with potential to collab within the dept/school and with close ties to the medical school and the college of biological sciences. Please apply if you are a good fit! 🤩
Our department @ucdavisvetmed.bsky.social @ucdavis.bsky.social is hiring! We welcome research that diversifies or complements existing strengths in gastrointestinal, neuroimmune, musculoskeletal, cardiorespiratory
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
November 29, 2025 at 6:58 PM
We are hiring! Please submit your application by Dec. 5! We are a basic science department housed in the school of vet med with potential to collab within the dept/school and with close ties to the medical school and the college of biological sciences. Please apply if you are a good fit! 🤩
Reposted by Grocott Lab
We're excited to host Dr Meha Patel from @earlhaminst.bsky.social next week for our CDMB seminar series! All welcome #UEAScience
November 28, 2025 at 3:00 PM
We're excited to host Dr Meha Patel from @earlhaminst.bsky.social next week for our CDMB seminar series! All welcome #UEAScience
Reposted by Grocott Lab
Hi everyone! We are the Evolutionary Modelling Group!
We are interested in many topics, from the evolution of microbial mutational robustness to the evolution of language and culture in humans. We rely on a variety of methods, both computational (evolutionary simulations) and mathematical.
We are interested in many topics, from the evolution of microbial mutational robustness to the evolution of language and culture in humans. We rely on a variety of methods, both computational (evolutionary simulations) and mathematical.
November 28, 2025 at 11:07 AM
Hi everyone! We are the Evolutionary Modelling Group!
We are interested in many topics, from the evolution of microbial mutational robustness to the evolution of language and culture in humans. We rely on a variety of methods, both computational (evolutionary simulations) and mathematical.
We are interested in many topics, from the evolution of microbial mutational robustness to the evolution of language and culture in humans. We rely on a variety of methods, both computational (evolutionary simulations) and mathematical.
Reposted by Grocott Lab
I don’t know if anyone else notices or cares, but when I see a presentation in which the speaker uses obviously generated-AI images to illustrate their slides, it makes me immediately less confident in whatever other content they’re presenting.
November 28, 2025 at 3:07 PM
I don’t know if anyone else notices or cares, but when I see a presentation in which the speaker uses obviously generated-AI images to illustrate their slides, it makes me immediately less confident in whatever other content they’re presenting.
Reposted by Grocott Lab
I'm old.
If you're not, listen to this.
Get a guitar or some drums, or a trumpet. Pick up a brush, a pencil, some clay or a welder.
Just make shit. It doesn't have to be good (eventually it will be) just make music, art or write or whatever.
It's literally never been more important.
If you're not, listen to this.
Get a guitar or some drums, or a trumpet. Pick up a brush, a pencil, some clay or a welder.
Just make shit. It doesn't have to be good (eventually it will be) just make music, art or write or whatever.
It's literally never been more important.
November 27, 2025 at 4:21 AM
I'm old.
If you're not, listen to this.
Get a guitar or some drums, or a trumpet. Pick up a brush, a pencil, some clay or a welder.
Just make shit. It doesn't have to be good (eventually it will be) just make music, art or write or whatever.
It's literally never been more important.
If you're not, listen to this.
Get a guitar or some drums, or a trumpet. Pick up a brush, a pencil, some clay or a welder.
Just make shit. It doesn't have to be good (eventually it will be) just make music, art or write or whatever.
It's literally never been more important.
Reposted by Grocott Lab
Me leaving the lab after seeing bands the right size in my colony PCR gel
Father Ted GIF
ALT: Father Ted GIF
media.tenor.com
November 27, 2025 at 6:46 PM
Me leaving the lab after seeing bands the right size in my colony PCR gel